Protein (view, download) , Domain (view, download)
PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  KRPQSRGKEKALSFLKFGKRSPKSPPTKDASWDSAVPPLPSNGDDGISTPFNFQHNIHVN
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  EGLVGLPPTWSAALSQAGFSDEEIIAIHNRRAAGSRSPNSQYVLNARPPSPRIPHPYQQS
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  ASNVPIIAQPGPRTTSLPRQVSDASLRSTSTRQRHPIPFGSPASASTASLHSSNAGSISN
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  IKAVRQGASQDHSSRNHTPQLSISYSSDSNHSGVSGEDVYQQSRNGNFPKDVSTPPGKPA
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  HAANPSIAQSFMSQASSLLNGHSHNRNESNASSTSKRLFGSQPSLWSSPSSSSTASRPQT
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  AANTSTSSNHSNAAVTQPTDNNASPEASPPQPKRTNALPPRLSLHQASGSGDLSAWAGML
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  LSGLSSDLDDKLTLGPSPLGPTPLTPQSAPASAATQGPSSFTVSNRPTHTSHSRSLGGES
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  SKARPEPLSELEEPIDNDAQYANLSPPWTGDAGSSSPLWSEIEGILSQGRSPTASEDRHE
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  PGPYSAALAETFSPTLPFSPEEDRMAQERRLRNEASRERLEREEDLNRLSVNTARPNRDS
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  SRSIPPTPIVPPPRQLPNRPAPIDAGHSPSPPNSSFDSEESSASSSQSQDRYPTPTTANS
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  TSSPLRYYLEPSPSPSQASFSPVVARHKEYPNVPPAYDIDEDLDEDDEEGTNLIIPHQII
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ------------------------------------------------------------
PAK2_Hsap        ------------------------------------------------------------
PAK1_Hsap        ------------------------------------------------------------
PAK3_Mmus        ------------------------------------------------------------
PAK2_Mmus        ------------------------------------------------------------
PAK1_Mmus        ------------------------------------------------------------
pak-1_Cele       ------------------------------------------------------------
STE20_Scer       ------------------------------------------------------------
SKM1_Scer        ------------------------------------------------------------
CLA4_Scer        ------------------------------------------------------------
Pak3_Dmel        ------------------------------------------------------------
Pak_Dmel         ------------------------------------------------------------
Y38F1A.10_Cele   ------------------------------------------------------------
PakA_Ddis        ------------------------------------------------------------
PakB_Ddis        ------------------------------------------------------------
PakC_Ddis        ------------------------------------------------------------
PakD_Ddis        ------------------------------------------------------------
19075_Tthe       ------------------------------------------------------------
25909_Tthe       ------------------------------------------------------------
PAK1_Spur        ------------------------------------------------------------
CC1G_15304_Ccin  TAPSPQANRPTIVIENVSPGGALSTALPTGTPASPFQRYRGWLSEVVQPLEEYIDEGVDP
CC1G_00840_Ccin  ------------------------------------------------------------
CC1G_02087_Ccin  ------------------------------------------------------------
AqueK235_Aque    ------------------------------------------------------------
GK081_Glam       ------------------------------------------------------------


PAK3_Hsap        ---YTRFEKIGQGASGTVYTALDI---------------------AT-GQ--EVAIKQMN
PAK2_Hsap        ---YTRYEKIGQGASGTVFTATDV---------------------AL-GQ--EVAIKQIN
PAK1_Hsap        ---YTRFEKIGQGASGTVYTAMDV---------------------AT-GQ--EVAIKQMN
PAK3_Mmus        ---YTRFEKIGQGASGTVYTALDI---------------------AT-GQ--EVAIKQMN
PAK2_Mmus        ---YTRYEKIGQGASGTVFTATDV---------------------AL-GQ--EVAIKQIN
PAK1_Mmus        ---YTRFEKIGQGASGTVYTAMDV---------------------AT-GQ--EVAIKQMN
pak-1_Cele       ---YRKVDKIGSGASGSVYTAIEI---------------------ST-EA--EVAIKQMN
STE20_Scer       ---YANLVKIGQGASGGVYTAYEI---------------------GT-NV--SVAIKQMN
SKM1_Scer        ---FQLVEKAGQGASGAVYLSKRIKLPQEN-DPRF-LK-SHCHR-VV-GE--RVAIKQIR
CLA4_Scer        ---FKVIEKAGQGASGSVYLAERTHIPTES-NMIELINNDIDEP-HV-GD--KVAIKQMV
Pak3_Dmel        ---YKTTQEVGKGASGIVFIAADL---------------------QN-ES--QVAVKTID
Pak_Dmel         ---YTKMEKIGQGASGTVYTAIES---------------------ST-GM--EVAIKQMN
Y38F1A.10_Cele   ---YEMKKQIGVGASGTVFVANVA---------------------GS-TD--VVAVKRMA
PakA_Ddis        ---YYNINKIGEGGAGEVFEAINS---------------------RT-NQ--TIAIKKMK
PakB_Ddis        --------KIGEGAAGEVFVVTQL---------------------KT-NN--KVAIKKMP
PakC_Ddis        ---YKNMTKIGEGAAGEVFVATSS---------------------KN-NK--RVAIKKIE
PakD_Ddis        ---YKVREVVGGGSTGKVYVGENS---------------------IT-GE--KVAIKKMK
19075_Tthe       ---YDFLSQIGKGATCKVYRCKNK---------------------QT-GQ--ECAMRVIR
25909_Tthe       ---YNFGDKLGKGAMCQVFKATKR---------------------KTKNE--EFAVRVMK
PAK1_Spur        ---YSKFEKIGQGASGVVYTAIEV---------------------AT-GQ--EVAIKQMN
CC1G_15304_Ccin  RDHYLDLKEIAEGESGSVFSARLIQKDADKLRLPAHVKAQDADDFAN-NREVLVAIKSVA
CC1G_00840_Ccin  ---YRNLVKIGQGASGGVYTAYQV---------------------GT-NM--SVAIKQMD
CC1G_02087_Ccin  ---YSKIKKVGQGASGHVYVAKEL---------------------AT-GK--KVAIKEMD
AqueK235_Aque    ---YTKMEKIGQGASGVVYTASEI---------------------AT-GN--EVAIKQMN
GK081_Glam       ---YSNPQEVGHGSSGHVYRATEIK---------------------T-GN--VVAIKSIS
                           . *    *:                                   *:: :

PAK3_Hsap        L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
PAK2_Hsap        L----------------QKQPKKELIINEILVMKELKN-PNIVNFLDSYLVG--DELFVV
PAK1_Hsap        L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
PAK3_Mmus        L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
PAK2_Mmus        L----------------QKQPKKELIINEILVMKELKN-PNIVNFLDSYLVG--DELFVV
PAK1_Mmus        L----------------QQQPKKELIINEILVMRENKN-PNIVNYLDSYLVG--DELWVV
pak-1_Cele       L----------------KDQPKKELIINEILVMRENKH-ANIVNYLDSYLVC--DELWVV
STE20_Scer       L----------------EKQPKKELIINEILVMKGSKH-PNIVNFIDSYVLK--GDLWVI
SKM1_Scer        L----------------SEQPKKQLIMNELLVMNDSRQ-ENIVNFLEAYIID-DEELWVI
CLA4_Scer        L----------------SKQPRKELIVNEILVMKDSRH-KNIVNFLEAYLRT-DDDLWVV
Pak3_Dmel        M----------------KNQSSKDLILTEIRVLKDFNH-KNLVNFLDAYLLEPEDQLWVV
Pak_Dmel         L----------------SQQPKKELIINEILVMRENKH-PNVVNYLDSYLVS--EELWVV
Y38F1A.10_Cele   F----------------KTQPKKEMLLTEIKVMKQYRH-PNLVNYIESYLVD-ADDLWVV
PakA_Ddis        L----------------KAQNLK-TVINEIGMMKNSNH-ENIVQYIDSYIVA-D-ELWVA
PakB_Ddis        L----------------NQQNMK-LIVTEIGIMKSCRH-QNIIDYIDSYLVG-D-SLWVA
PakC_Ddis        I----------------NNDNAK-LLVTEIAIMKTSHH-DNIVNYIDSYIVN-DRELWVA
PakD_Ddis        V----------------DNNNIK-NIINEISTMKNSKH-KNVIKYVSSHLVI-N-HIWLI
19075_Tthe       M----------------LNPDQIEKTKMEILLMNESKN-NNIVQYYKSYIYM--DVIFMA
25909_Tthe       L----------------GDEGSMNKIKIEMAIMKICQH-KNIVRYYETFKFM--SCLFMV
PAK1_Spur        L----------------QQQPKKELIINEILVMRENKH-QNIVNYLDSYLVS--DELWVV
CC1G_15304_Ccin  IV--------------PSGSPKLKDLQHELGLMKGLHH-ENVIGLDSLYVDFLEDTLWIR
CC1G_00840_Ccin  L----------------DKQPKKDLIINEILVMRSSRH-PNIVNYIDSFLYK--NDLWVV
CC1G_02087_Ccin  L----------------SHQPRKELIVNEILVMKESQH-PNIVNFLNSYLVK-NNELWVV
AqueK235_Aque    L----------------QQQPKKELIINEIIVMKEIKQ-PNIVNFLDSYLVG-ESELWVV
GK081_Glam       AINFLTDDGKKVRDIKSAEAATLMALKNEVALMYLSKECEYIVKLHKVYFSKAAKEFYMI
                                             *:  :   ..   ::   . .       :::

PAK3_Hsap        MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALDFLHS
PAK2_Hsap        MEYLAGGSLTDVVTE---------------------TCMDEAQIAAVCRECLQALEFLHA
PAK1_Hsap        MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALEFLHS
PAK3_Mmus        MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALDFLHS
PAK2_Mmus        MEYLAGGSLTDVVTE---------------------TCMDEAQIAAVCRECLQALEFLHA
PAK1_Mmus        MEYLAGGSLTDVVTE---------------------TCMDEGQIAAVCRECLQALEFLHS
pak-1_Cele       MEYLAGGSLTDVVTE---------------------CQMEDGIIAAVCREVLQALEFLHS
STE20_Scer       MEYMEGGSLTDVVTH---------------------CILTEGQIGAVCRETLSGLEFLHS
SKM1_Scer        MEYMEGGCLTDILDAVARSN----T-------GEHSSPLNENQMAYIVKETCQGLKFLHN
CLA4_Scer        MEFMEGGSLTDIIENSPTND-------------NSHSPLTEPQIAYIVRETCQGLKFLHD
Pak3_Dmel        MEYMDGGPLTDVVTE---------------------TVMKERQIACVCRETLYAISFLHA
Pak_Dmel         MEYLPGGSLTDVVTE---------------------TCMDEGQIAAVCREVLQALEFLHA
Y38F1A.10_Cele   MDYLEGGNLTDVVVK---------------------TELDEGQIAAVLQECLKALHFLHR
PakA_Ddis        MEFMSGGCLTEVLDQYR------------------DIQLNESQIAFVCQEVLRGLEYIHK
PakB_Ddis        MEFMGGGCLTEILEQFN------------------SVKLVEAQIAYVCAETLKGLAYIHS
PakC_Ddis        MEFMGGGCLTDILEAFD------------------NIKMSEIQIAYVVKETLKALQYIHS
PakD_Ddis        MEYMSYGSLTDLISNCINIQCNGNNQQQQQQQQQQQTYFIESHIAYICQQVLQGMDYIHK
19075_Tthe       IEYMNAGSLTELIYGN-------------------FSFLSEQMASYICEQILFGLFFIHR
25909_Tthe       IEYMNGGSLTEIIYQN-------------------FKTIPEDIIAYILREIIQGLNFIHL
PAK1_Spur        MEFLAGGSLTDVVTE---------------------TCMDEGQIASVCRECLQALQFLHQ
CC1G_15304_Ccin  MELME-RSLADIIGLVD-----------------AGLMLPDRMMARFASDILSGLDYLQR
CC1G_00840_Ccin  MEYMEGGSLTDVVTA---------------------NLMTEGQIAAVSRETCQGLEHLHR
CC1G_02087_Ccin  MEYMEGGALTDVIEN---------------------NTLEEDQISSICLETCKGLQHLHS
AqueK235_Aque    MEYLAGGSLTDVVTE---------------------TCMNEGQIAAVCRECLQALKFLHD
GK081_Glam       MDYCNANCLTNILSRH-------------------GYIKNERVSCMIIRDILKALNHLHE
                 ::      *::::                           :     .  :   .: .::

PAK3_Hsap        NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK2_Hsap        NQVIHRDIKSDNVLLGME----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK1_Hsap        NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK3_Mmus        NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK2_Mmus        NQVIHRDIKSDNVLLGME----------------GSVKLTDFGFCAQITPEQSKRSTMVG
PAK1_Mmus        NQVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQITPEQSKRSTMVG
pak-1_Cele       RHVIHRDIKSDNILLGMD----------------GSVKLTDFGFCAQLSPEQRKRTTMVG
STE20_Scer       KGVLHRDIKSDNILLSME----------------GDIKLTDFGFCAQINELNLKRTTMVG
SKM1_Scer        KKIIHRDIKSDNILLNSQ----------------GLVKITDFGFCVELTEKRSKRATMVG
CLA4_Scer        KHIIHRDIKSDNVLLDTR----------------ARVKITDFGFCARLTDKRSKRATMVG
Pak3_Dmel        KGIIHRDIKSDNVLLGMD----------------GSVKVTDFGFCANIEG-DEKRQTMVG
Pak_Dmel         NQVIHRDIKSDNILLGLD----------------GSVKLTDFGFCAQISPEQSKRTTMVG
Y38F1A.10_Cele   HSIVHRDIKSDNVLLGMN----------------GEVKLTDMGFCAQIQP-GSKRDTVVG
PakA_Ddis        FNRIHRDIKSDNILIGAN----------------GEIKLADFGYAAQLTQIRQERNSVVG
PakB_Ddis        QHRIHRDIKSDNILLGSD----------------GSVKLADFGYAAQLTKSKQKRVTIVG
PakC_Ddis        LHRIHRDIKSDNILLGSE----------------GSVKIADFGYAAQLTQKQQKRNTVVG
PakD_Ddis        GHRTHRDIKSDNILLGKD----------------GSVKIADFGFVANLTRKKLQRNSVVG
19075_Tthe       TNQIHRDLKSDNILLNQN----------------GDVKIADFGFATQLTREHFSKKSQVG
25909_Tthe       QNQAHRDLKSDNILVNKN----------------GEVKVADFGFATQLTQEKQRRKSVVG
PAK1_Spur        RHVIHRDIKSDNILLGMD----------------GNVKLTDFGFCAQITPEQSKRTTMVG
CC1G_15304_Ccin  HHIAHRDVRSDNLLINKH----------------GVLKLTDFANAVQVSAQNPMRTEPAG
CC1G_00840_Ccin  HGVIHRDIKSDNVLLSMV----------------GDIKLTDFGFCAQISEGHAKRTTMVG
CC1G_02087_Ccin  QSIIHRDIKSDNVLLDAQ----------------GRVKITDFGFCAKLTDQKSKRATMVG
AqueK235_Aque    NHVIHRDIKSDNILLGMD----------------GQVKLTDFGFCAQITPEQSKRSTMVG
GK081_Glam       NHRIYRDLKSDNVLLNAELINSLAQDGAITKKKKFSLKLSDFGFAVQLNTKQPTRKSVVG
                     :**::***:*:.                    :*::*:.  ..:      :   .*

PAK3_Hsap        TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK2_Hsap        TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK1_Hsap        TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQN
PAK3_Mmus        TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK2_Mmus        TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
PAK1_Mmus        TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQN
pak-1_Cele       TPYWMAPEVVTRKQYGPKVDVWSLGIMAIEMVEGEPPYLNENPLRAIYLIATNGKPDFPG
STE20_Scer       TPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKE
SKM1_Scer        TPYWMAPEIVNQKGYDEKVDVWSLGIMLIEMIEGEPPYLNEDPLKALYLIANNGSPKLRH
CLA4_Scer        TPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKH
Pak3_Dmel        TPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKS
Pak_Dmel         TPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKE
Y38F1A.10_Cele   TPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQNGKPEIKQ
PakA_Ddis        TPYWMAPELIRGNNYDFKVDVWSLGIMTREMAEGEPPYLEFPPLRALFLLTTQGLPPIRD
PakB_Ddis        TPYWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYMSFPPLRALFLITTKGIPDLKD
PakC_Ddis        TPYWMAPELIRGHDYGVKVDIWSLGIMMMEMAEGEPPYMDFPPLRALFLITTKGIPPLKE
PakD_Ddis        TPYFMAPELIRGNQYNHKVDIWSLGILARELSEGEPPYAKYPPVRALFLLTLEGVPDFKE
19075_Tthe       TPAWMAPELILRKDYSQKVDIWSLGVICIEILEGEPPYIRDKPAKAMYYITKK-KPHKLD
25909_Tthe       TPAWMAPELILKKEYNEKVDVWSTGIIAIELAMGEPPHLRMPPLKAMYTISSKAPPRL-D
PAK1_Spur        TPYWMAPEVVTRKQYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPDIHN
CC1G_15304_Ccin  VLYWQAPEVRSPPYNAMKVDVWSLGATVWEMAETQPPFADTNEFG-------DRWPPLSR
CC1G_00840_Ccin  TPYWMAPEVVTRKEYGPKVDIWSLGIMAIEMIEGEPPYLNQNPLKALYLIATNGTPTIAN
CC1G_02087_Ccin  TPYWMAPEVVKQKEYGAKVDIWSLGIMAIEMIENEPPYLDEEPLKALYLIATNGTPTLKK
AqueK235_Aque    TPYWMAPEVVTRKQYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN
GK081_Glam       TPFWMAPELIRGTEYNTKVDCWSLGIVVLELCESLPPHMEMQPLKAVFKIVTSPAPSFKK
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PAK3_Hsap        PERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL
PAK2_Hsap        PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL
PAK1_Hsap        PEKLSAIFRDFLNRCLEMDVEKRGSAKELL----Q
PAK3_Mmus        PERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL
PAK2_Mmus        PEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFL
PAK1_Mmus        PEKLSAIFRDFLNRCLEMDVEKRGSAKELL----Q
pak-1_Cele       RDSMTLLFKDFVDSALEVQVENRWSASQLLTHPFL
STE20_Scer       PENLSSSLKKFLDWCLCVEPEDRASATELLHDEYI
SKM1_Scer        PESVSKQTKQFLDACLQVNVESRASVRKLLTFEFL
CLA4_Scer        PESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFF
Pak3_Dmel        WDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFL
Pak_Dmel         KDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFL
Y38F1A.10_Cele   RDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPFL
PakA_Ddis        AHKWSKEFNDFLALCLEKDTEKRASSSSLLHHPFL
PakB_Ddis        QNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFL
PakC_Ddis        TTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM
PakD_Ddis        PNKWSSDFIEFVNLCLNLDDKRRPDAHYLLRHPFL
19075_Tthe       ATKFSQEACDFVSTCLNIDPQERPTAQQLISHPFI
25909_Tthe       PANFTQNFCNFVEQCLQKNPDERASFQTLLEHPFL
PAK1_Spur        PDRLSPVFRNFLAKCLETDVDKRADGEMLLKHPFL
CC1G_15304_Ccin  PQLVSPAFHEFLRLCSEP-AASRPTAGELLKTPFV
CC1G_00840_Ccin  PENLSPVFTDYLAKTLEVDAEKRPSATELLQHPFF
CC1G_02087_Ccin  PEALSKELKSFLAVCLCVDVASRATAIELLDHEFL
AqueK235_Aque    PENLSRVFRDFLDRCLEMEVDKRGSASELLTHVFL
GK081_Glam       PSQWTPELNDFLARCLDKDPDSRWSCAQLLEHPWI
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