Gene 86827.m00367 (T.vaginalis)

86827.m00367

Species: T.vaginalis
Alias: 86827.m00367, TvagK0919
External Links:
Annotation:

Classification

Group: Other
Family: CDC7

Sequence

Name Sequence Type Origin Length Description Download
86827.m00367.AA Protein None 326 None Fasta, JSON
86827.m00367.kin_dom Protein Kinase Domain None 309 None Fasta, JSON

Protein domain

Protein domains of 86827.m00367.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 86827.m00367.AA S_TKc 10-318 23 6.8e-65 222.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-318
Range on HMM: 1-231/231
Sequence Identity: 23% (77 aa)

FTIHELIGTGSFSTVFHATDKK-GRHYALKRLFWNNAPDRILKELQWICYLDHPNIVKCHACFRTVDQATLVMEYIPH--IPFRQLLSK---------MN
..|...|| |.|..|. ...|| ||..|.|..      ..|..|.|     .||||||.. .|.. |   .||||...     .... |         ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

NLTIQHYMYGLLSALAYMHSKKIIHRDVKPANFLFDPKTMRGVLIDFGLCEEDMSIKTATPQVADSSENDFDLQFPHLCQNRQKMMANRAGTRGFRSPEV
  ....||| ...||.|.||..|||||.||.| |.|    .  ..||||. .                                      ||. ...|||
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------------------------------TTFCGTPWYMAPEV

LFAAWNQTL-TIDIWSAGVVLLSILSQRYPFFKSPDDLTSLCEISVLVGTEKLYAAAKECGRKLRFPVEQKGYNMQELCTRLNSTIDDMNLDPSVFDLLE
|      .   .|.|| |..|   |. . ||     ..  . .. .                                             .|.. |...
L----GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---------------------------------------------SPEAKDFIR

KMLEPIPSLRITSEEALK-------HPFF
|.|.  |. |.|  |||.       ||.|
KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86827.m00367.AA CDC7 10-154 35 4.9e-58 171.35 In-house 1-163 (522) Show / Hide 
Range on Protein: 10-154
Range on HMM: 1-163/522
Sequence Identity: 35% (58 aa)

FTIHELIGTGSFSTVFHATDKKGR------------H---YALKRLFWNNAPDRILKELQWICYLD-HPNIVKCHACFRTVDQATLVMEYIPHIPFRQLL
...|. || | ||.|. ||.....            .    |.|...  . |.||..|||    .  |.|... . |||  |....||.| || .|. ..
YKVHDKIGEGTFSSVYKATCQRQPHVNKFASHFWNYCRRKFAIKHHIPTSHPERIMNELQCLTRMGGHHNVMGMCCCFRYNDHVHIVMPYFPHCSFQDFY

SKMN--NLTIQHYMYGLLSALAYMHSKKIIHRDVKPANFLFDPKTMRGVLIDFGLCEEDMSIK
  ||  .  |.|||| |. ||.. |.. |||||||| |||. ..| ...|.|||| ...|. .
FHMNRDMEEIKHYMYNLFYALRHVHQFGIIHRDVKPSNFLYNRRTKKFLLVDFGLAQHMMDYN
Kinase 86827.m00367.AA CDC7 175-318 31 1.7e-57 169.7 In-house 317-522 (522) Show / Hide 
Range on Protein: 175-318
Range on HMM: 317-522/522
Sequence Identity: 31% (65 aa)

LCQNRQKMMANRAGTRGFRSPEVLFAAWNQTLTIDIWSAGVVLLSILSQRYPFFKSPDDLTSLCEISVLVGTEKLYAAAKECGRKLRFPVEQKGYNMQEL
.|  .  . ||||||.|||.||||.   .||  |||||.||..||.|| |||||..|||.|.| .|  . |.|.   .|.  | |.   .|     . ||
CCMCPKQQHANRAGTPGFRAPEVLLKCPDQTTAIDIWSCGVIFLSLLSGRYPFFMAPDDMTALAQIMTIFGSEEIIKMAHFFGKKIECSHEFPAQDWREL

CTRLN--------------------------------------------------------------STIDDMNLDPSVFDLLEKMLEPIPSLRITSEEA
| ..                                                               . ..   .... .|||.. ||. |  ||| |||
CRCYWYMDSLPNRTSDIQGHAQHQPAKSKQTDHKASRVQRSQNQHSPDSFYKRDSDECWHCGPICSKHMWKWEEFPDEAYDLLDRCLEMNPHKRITAEEA

LKHPFF
||||||
LKHPFF
Kinase 86827.m00367.AA Ciliate-E2 10-318 19 1.5e-55 189.12 In-house 1-365 (365) Show / Hide 
Range on Protein: 10-318
Range on HMM: 1-365/365
Sequence Identity: 19% (84 aa)

FTIHELIGTGSFSTVFHATD-KKGRHYALKRLFWNN----------------------APDRILKELQWIC-----------------YLDHPNIVKCHA
. ....||.|.|..|. ... |... .|.|.   ..                         ...|  . |.                  |.||||.|.. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

CFR--TVDQATLVMEYIPHIPFRQLLS--------------KMNNLTIQHYMYGLLS---------------ALAYMHSKK-IIHRDVKPANFLFDPKTM
||   . .   |||||. .   ....               ...   |...|. .|.               || |.|||. ||||| || | ||     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

RGVLIDFGLCEE----------------------------DMSIKTATPQVADSSENDFDLQFPHLCQNRQKMMANRAGTRGFRSPEVLFAAWN------
   .|||||. .                            .|..                          | |  . .|| |. .||.|    .      
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQ-----------------------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ

--QTLTIDIWSAGVVLLSILSQRYPFFKSPDDLTSLCEISVLVGTEKLYAAAKECGRKLRFPVEQKGYNMQELCTRLNSTI-DDMNLDPSVFDLLEK---
   .  .||||.||.|   |. ..||                          . .  |..|| .... .    |  .   . .  ...... ||. |   
KGYDYKCDIWSLGVILYEMLFGKPPF------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKKWSQECKDLIKKFGK

-MLEPIPSLRIT-SEEALKHPFF
 ||.  |. |||  |..|.||.|
RMLQKDPEKRITGWEQILNHPWF
Kinase 86827.m00367.AA Pkinase 10-318 23 2.5e-53 188.27 Pfam 1-293 (293) Show / Hide 
Range on Protein: 10-318
Range on HMM: 1-293/293
Sequence Identity: 23% (79 aa)

FTIHELIGTGSFSTVFHATDKKGRH-YALKRLFWNNAPDRILK------ELQWICYLDHPNIVKCHACFRTVDQATLVMEYIPHI----PFRQLLS----
..|.. || |||..|.....|. .. .|.|..   .. .  ..      |.|    |.|||||... .|.. |   .|||| ..         ..|    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

-KM--NNLTIQHYMYGLLSALAYMHSKKIIHRDVKPANFLFDPKTMRG----VLIDFGLCEE-DMSIKTATPQVADSSENDFDLQFPHLCQNRQKMMANR
 ..     ....||| .|..|.|.||..|||||.||.|.|.| ...       ..||||..  |                            ..  |  .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD--------------------------Y-NNS-MTTF

AGTRGFRSPEVLFAAWNQTLTIDIWSAGVVLLSILSQRYPFFKS---PDDLTSLCEISVLVGTEKLYAAAKECGRKLRFPVEQKGYNMQELCTRLNSTID
.||.....|||.  .   .  .|.||.|..|   |. | ||  .   .. .. .  |    |..  .   ..| . ..| . .          . ..|  
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H------F-HWTF-

DMNLDPSVFDLLEKMLEPIPSLRITSEEALKHPFF
  |....  |.....|.. |. |.| |..|.||.|
-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 86827.m00367.AA CMGC 10-318 17 1.7e-52 170.35 In-house 1-513 (513) Show / Hide 
Range on Protein: 10-318
Range on HMM: 1-513/513
Sequence Identity: 17% (92 aa)

FTIHELIGTGSFSTVFHATDKK---------------GRHYALKRLF-------------WNNAPDRILKELQWICYL-----------------DHPNI
..| . || |....|. ..||.               ....|.|...              .. | |.| |..   .|                 .|.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VKCHACFRTVD-----------------QATLVMEYIPHIPFRQLLSKMNN-----------------------LTIQHYM------YGLLSALA--YMH
||.. .|.. .                 .  ||.||..|    |.. ....                        .|...|      | .| .|.  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SKK--IIHRDVKPANFLFDPKT-------------------MRGVLIDFGLCE--EDMSIKTATPQVADSSENDFDLQFPHLCQNR--------QKMMAN
|..  ||||| ||.| |.....                   .|  ..||||.   .. | .....|        |          .        .... .
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQS-----F----------KNVNKDDKPNRPYTH

RAGTRGFRSPEVLFAAWNQT---------LTIDIWSAGVVLLSILSQ-------RYPFFK-----------SPDDLTSLCEISVLVG-------------
.  ||  |.||.|. . . |          .||.||.| ..  ..         ..|.|.             ...  | .|  . |             
YVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHF

-----TEKLYAAAK---------------------ECGRKLRFP----VEQKGYNMQELCTRLNSTIDDM---------------------------NLD
     .|. .   |                     | .|. ...     .... . ..|. ... ..|                             ..|
NFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDD-NNKKAMVFNWIYEEKFKSHKFNHQFKRKCCD

PSVFDLLEKMLEPIPSLRITSEEALKHPFF
|  .|||.|||.  |. ||| |.||.||.|
PQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 86827.m00367.AA Ciliate-E2-Unclassified 10-318 20 7e-51 174.73 In-house 1-352 (352) Show / Hide 
Range on Protein: 10-318
Range on HMM: 1-352/352
Sequence Identity: 20% (82 aa)

FTIHELIGTGSFSTVFHATDKKGRHYA------------LKRLFWNNAPDRILKELQWICY------------------LDHPNIVKCHACFRTVDQATL
..|.. ||.|.|..|... .||   ..             ...  |.  . ....... .                   ..||.|||.. ||.. .   .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYIPHIPFRQLLSK------------MNNLT--------IQ-----HYMYGLLSALAYMHSKK-IIHRDVKPANFLFDPKTM--RGVLIDFGLCE--E
||||...   .| ..|            .|...        ..     .|.. .|..| |.|.|. ||||| || | ||| . .  .  .||||..   .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

DMSIKTATPQVADSSENDFDLQFPHLCQNRQKMMANRAGTRGFR----SPEVLFA-AWNQTLT--IDIWSAGVVLLSILSQRYPFF-KSPDD--------
... .. | |           | . . ...|.||  ..|| ..     .||||     ...    .|||| ||.|  .| ..|||. .. ..        
QNNNCD-TNQ-----------Q-QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQW

--------LTSLCEISVLVGTEKLYAAAKECGRKLRFPVEQKGYNMQELCTRLNSTIDDMNLDPSVFDLLE----KMLEPIPSLRITSEEALKHPFF
        | . .    .   .                                   ......|.. |...    |||.  |. ||| |..|.||.|
INNAYRKQLYQNIKQKNIQFPKFPWQQ------------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86827.m00367.AA CAMK 15-318 16 8.7e-41 128.68 In-house 1-425 (425) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-425/425
Sequence Identity: 16% (79 aa)

LIGTGSFSTVFHATDK-KG------------RHYALKRLF----------------------------W--NNAPDRILKELQ--WICY-----LDHPNI
 .|.|||..|. ...|  .            ...| | .                             |   .  .....|..  . .      ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKCHACFR------------TVDQ--------ATLVM---EYIPHI----P-FRQLLSK-----------------MNNLTIQHYMYGLLSALAYMHSKK
.|..  .             | ..          .||   ||..        |  . ..                 ..    ..|.  ..||..|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDVKPANFLFDPKT----------------MRGVLIDFGLC-----------------EEDMSIKTATPQVADSSENDFDLQFPHLCQNRQ------
|.||| || | |.| .                     .||||.                  .| |  .                         |      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN-------------------------QWTTPTE

-KMMANRAGTRGFRS-PEVLFA----AWN---------QTLTIDIWSAGVVLLSILSQRYPFFKSP--DDLTSLCEISVLVGTEKLYAAAKECGRKLRFP
 ..|  . || .. . ||||      ..           .  .|.||.||.|   |. ..||  .   ...  . |                        
GQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E-W----------------------

VEQKGYNMQELCTRLNSTIDDMNLDP--------------------------SVFDLLEKMLEPIPSLRITSEEALKHPFF
    |.|..||. .  .   |.  ..                          .. ||. |||.. |. |.| |..|.||..
---IGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 86827.m00367.AA STE 10-147 24 8.6e-28 95.28 In-house 1-194 (359) Show / Hide 
Range on Protein: 10-147
Range on HMM: 1-194/359
Sequence Identity: 24% (49 aa)

FTIHELIGTGSFSTVFHATDKK----------------GRHYALKRLFWNNA-------------------PDRILKELQWICYLD--HPNIVKCHACFR
... | || |.| ||. | ..|                |. .| |..  .|                     ..||||..    ..  ||||||.. |. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TV-------DQATLVMEYIPHIPFRQLLS-----------------KMNNLTIQHYMYGLLSA-LAYMHSKKIIHRDVKPANFLFDPKTMRGVLIDFGLC
         |.  ..|||..   .....                  ...   | .. . .| . |.| ||..|||||.|||| |.        |.|||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC
Kinase 86827.m00367.AA CK2 10-148 32 1.5e-26 75.62 In-house 1-144 (288) Show / Hide 
Range on Protein: 10-148
Range on HMM: 1-144/288
Sequence Identity: 32% (47 aa)

FTIHELIGTGSFSTVFHATDKKGRHYA--LKRLFWNNAPDRILKELQWICYLD-HPNIVKCHACFR-TVDQAT-LVMEYIPHIPFRQLLSKMNNLTIQHY
. . . || | .| ||.. ..|  .    . ..   .   .|  |.. .  |  .|||.|  .  .  . . . || ||.  . ||||  ... . |..|
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

MYGLLSALAYMHSKKIIHRDVKPANFLFDPKTMRGVLIDFGLCE
|. || || | ||. |.||||||.| . |..  .  ||| || |
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAE
Kinase 86827.m00367.AA AGC 60-217 21 5.4e-25 60.18 In-house 88-295 (395) Show / Hide 
Range on Protein: 60-217
Range on HMM: 88-295/395
Sequence Identity: 21% (51 aa)

DHPNIVK-CHACFRTVDQ--ATLVMEYIP----------H-IPFRQLLS-----KMNNLTIQHYMY-------GLLSALAYMHS-KKIIHRD-VKPANFL
.||.|||  | .| . |     .||||.|              | .|       ...  ....|.         ...|| |.|| ..||||| .|| | |
HHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENIL

FDPKTMRGVLIDFGLCEEDMSIK------------------------TATPQVADSSENDFDLQFPHLCQNRQKMMANR------------------AG-
.| .     | ||||| | |. .                        . | .                 .|......|.                   | 
LDED-GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMD-T-N---------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGP

-TRGFRSPEVLFAAWNQTLTIDIWS--AGVVL
 |  . .||.|      . . |.||   |...
CTPEYMAPEIL-----YGKACDWWSFGLGCLM
Kinase 86827.m00367.AA CAMKL 10-149 26 2e-23 71.51 In-house 1-178 (297) Show / Hide 
Range on Protein: 10-149
Range on HMM: 1-178/297
Sequence Identity: 26% (47 aa)

FTIHELIGTGSFSTVFHATD-KK-GRHYALKRLFWNNAPD-----------------RILKELQWICYLD---HPNIVKCHACFRTVDQ------ATLVM
..| . .|.|||..|  ||. .  |...| | .  . . .                 || .| |    |.   ||||.| . .. | .         |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYIPHIP--FRQLL-------SKMNNLTIQHYMYGLLSALAYMHSKKIIHRDVKPANFLFDPKTM-RGVLIDFGLCEE
||..       . .        .|     ..|   ..||..|.||..|.||| || | |.| . .    .||||.. .
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNM
Kinase 86827.m00367.AA CK2 186-318 28 5.6e-23 64.76 In-house 155-288 (288) Show / Hide 
Range on Protein: 186-318
Range on HMM: 155-288/288
Sequence Identity: 28% (38 aa)

RAGTRGFRSPEVLFAAWNQTLTIDIWSAGVVLLSILSQRYPFFKSPDDLTSLCEISVLVGTEKLYAAAKECGRKLRFPVEQ-KGYNMQELCTRLNSTIDD
| ..| .. || |         .|.|| |... |.. .. |||.  |  . | .|    ||| ||.  .  | .|   ...  . . .   .|.     .
RVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGHDNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENK

MNLDPSVFDLLEKMLEPIPSLRITSEEALKHPFF
   .| . |.|.|||   .  |||  ||..||.|
HLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 86827.m00367.AA CDK 10-146 29 4.7e-22 67.21 In-house 1-159 (284) Show / Hide 
Range on Protein: 10-146
Range on HMM: 1-159/284
Sequence Identity: 29% (51 aa)

FTIHELIGTGSFSTVFHATDKK-G-----RHYALKRLFWNN--------APD-------RILKELQWICYLDHPNIVKCHACFRTVDQA-----------
. . | || |.. .|. | ||. |     . .|||..   |                   .||||       |||||| | .. | . .           
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-------HPNIVKLHDVCHTKNMDRNNKDKHENKL

TLVMEYIPHIPFRQLLSKMNNLTIQHYMYGLLSALAYMHSKKIIHRDVKPANFLFDPKTM--RGV--LIDFGL
..|.||..|    ....      |..||. ||..|.|.||..|.||| ||.| | . .    .|.  . ||||
YMVFEYMDH-DLKKYMD------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGL
Kinase 86827.m00367.AA AGC 10-40 34 9.9e-11 22.45 In-house 1-38 (395) Show / Hide 
Range on Protein: 10-40
Range on HMM: 1-38/395
Sequence Identity: 34% (13 aa)

FTIHELIGTGSFSTVFHATDKK-------GRHYALKRL
| .. .||.|||..|. . .|.       |. ||.| |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVL
Kinase 86827.m00367.AA CDK 293-318 57 1.6e-10 29.75 In-house 259-284 (284) Show / Hide 
Range on Protein: 293-318
Range on HMM: 259-284/284
Sequence Identity: 57% (15 aa)

DLLEKMLEPIPSLRITSEEALKHPFF
|||.|||   |. ||..|.||.||.|
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 86827.m00367.AA AGC 283-318 28 1.1e-09 19.66 In-house 350-395 (395) Show / Hide 
Range on Protein: 283-318
Range on HMM: 350-395/395
Sequence Identity: 28% (13 aa)

DDMNLDPSVFDLLEKMLEPIPSLRIT----------SEEALKHPFF
.| ...|   ||..|.|.. |. |..           ||  .||.|
EDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 86827.m00367.AA TyrKc 10-221 16 7.5e-09 -79.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-221
Range on HMM: 1-280/280
Sequence Identity: 16% (47 aa)

FTIHELIGTGSFSTVFHATDKKGRHYALKRLFWNNAPDRILKELQWICYL--DHPNIVKCHACFRTV-------DQATLVMEYIPHIPFRQLLSKMNN--
 |  . .| | | .|...| |  .  | | |  .     ...|..  | |  .|||||..... ..        ..  .|||| ||   .. | |  .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

--LTIQHYMYGLLSALAYMHSKKIIHRDVKPANFLFDPKTMRGVLI-DFGLCEEDMSI-------KTATPQ---VAD--------SSENDFDL-------
   .  ....   .  .| |||..||||    | | . .    | | ||||. .  .        .. ...    ..        . |  ..        
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

---------------QFPHLCQ----NRQKMMANRAGTRGFRSPEVL---------FAAWNQTLTIDIWSA-------GVVLLSIL
               | |.  .       . . ..  ... . .             ..  | .  . | .          . ...
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase 86827.m00367.AA Pkinase_Tyr 10-125 25 1.1e-08 30.06 Pfam 1-137 (270) Show / Hide 
Range on Protein: 10-125
Range on HMM: 1-137/270
Sequence Identity: 25% (35 aa)

FTIHELIGTGSFSTVFHATDK-----KGRHYALKRLFWNNAPDR------ILKELQWICYL-DHPNIVKCHACFR-TVDQ--ATLVMEYIPHIPFRQLLS
 |. . .| |.| .|...| |     .. . | | |  ..| ..       ..|..  . | .|||||.....     ..    .|||| ||   .  | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KM----NNLTIQ---HYMYGLLSALAYMHSKKIIHRDV
|     ..||..   .. .   ....| .||..||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 86827.m00367.AA CAMKL 293-318 38 1.2e-07 20.34 In-house 272-297 (297) Show / Hide 
Range on Protein: 293-318
Range on HMM: 272-297/297
Sequence Identity: 38% (10 aa)

DLLEKMLEPIPSLRITSEEALKHPFF
||. |||.. |. |.| .. ..||..
DLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 86827.m00367.AA STE 293-318 39 8e-06 16.75 In-house 332-359 (359) Show / Hide 
Range on Protein: 293-318
Range on HMM: 332-359/359
Sequence Identity: 39% (11 aa)

DLLEKMLEPIPSLRITSEEALK--HPFF
| ..| |.  |. | |... ||  |||.
DFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 86827.m00367.AA CDK 193-228 30 6.7e-05 11.43 In-house 186-225 (284) Show / Hide 
Range on Protein: 193-228
Range on HMM: 186-225/284
Sequence Identity: 30% (12 aa)

RSPEVLFAAWNQT--LTIDIWSAGVVLLSILS--QRYPFF
|.||.|. . . .   .||.||.| ..  ..   .| |.|
RAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF
Kinase 86827.m00367.AA CAMKL 208-227 45 0.00013 10.47 In-house 217-236 (297) Show / Hide 
Range on Protein: 208-227
Range on HMM: 217-236/297
Sequence Identity: 45% (9 aa)

IDIWSAGVVLLSILSQRYPF
.||||.||.|  ..  ..||
VDIWSCGVILYAMVCGYLPF