Gene CDC7 (Mouse)

CDC7

Species: Mouse
Alias: Cdc7l1, CDC7
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Other
Family: CDC7

Sequence

Name Sequence Type Origin Length Description Download
CDC7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 508 Kinase domain by global Sugen HMM Fasta, JSON
CDC7.NA RNA Sugen 2960 None Fasta, JSON
CDC7.AA Protein Sugen 564 None Fasta, JSON

Protein domain

Protein domains of CDC7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDC7.AA CDC7 52-559 57 0.0 1163.63 In-house 1-522 (522) Show / Hide 
Range on Protein: 52-559
Range on HMM: 1-522/522
Sequence Identity: 57% (300 aa)

FKIKDKIGEGTFSSVYLATAQLQEG-----------HEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHESFLDIL
.|..||||||||||||.||.|.|..           ...|.|.||.||||||.||..||||||..||..||||...|||.||||.|.|||..|.||.|..
YKVHDKIGEGTFSSVYKATCQRQPHVNKFASHFWNYCRRKFAIKHHIPTSHPERIMNELQCLTRMGGHHNVMGMCCCFRYNDHVHIVMPYFPHCSFQDFY

NSLS--FQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKYHGVVGHKGLLSRPAPK
....  ..|...||||||.||...|||||.||||||||||||||.||..||||||||...|.........||..|||.|..||||...|.|.||.||.||
FHMNRDMEEIKHYMYNLFYALRHVHQFGIIHRDVKPSNFLYNRRTKKFLLVDFGLAQHMMDYNECSRSHQQSKMQQERCNQNKYHSISGNKALLRRPPPK

TVDQQCTPKTSVKRSYT--QVHIKQGKDGKERSVGLSVQRSVFGERNFNIHSSISHESPAEKLIKQSKTVDIISRKLATKKTAISTKAMNSVMRETARSC
|.|||...|..|||.|.  |.|||||||.|......||.|.|||.||||.||..||..|..|..||...||...||..|.|...||||||..||..|.||
TQDQQHSNKNNVKRNYNNNQHHIKQGKDDKNDHNNFSVMRNVFGNRNFNMHSNNSHNNPNNKNMKQNNNVDNNNRKNNTQKRICSTKAMNGTMRKNAMSC

PAVLTCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGK
.....|.||.||..|..|....||.|.|||||||||||||.||||||||||.||.||||||||||||||..|.||.|||||||||.||.|.|..|..|||
DPQCCCCCYKSDKCCNCCMCPKQQHANRAGTPGFRAPEVLLKCPDQTTAIDIWSCGVIFLSLLSGRYPFFMAPDDMTALAQIMTIFGSEEIIKMAHFFGK

SVLCSKEVPAQDLRALCERLRGLDSTTPRSASGPPGNASYDPAASKNTDHKASRVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLL
...||.|.||||.|.||......||...| .|...|.|...||.||.|||||||||..|.|||.||.||||.|..|.....|......|...||||||||
KIECSHEFPAQDWRELCRCYWYMDSLPNR-TSDIQGHAQHQPAKSKQTDHKASRVQRSQNQHSPDSFYKRDSDECWHCGPICSKHMWKWEEFPDEAYDLL

DKLLDLNPASRITAEAALLHAFF
|..|..||..|||||.||.|.||
DRCLEMNPHKRITAEEALKHPFF
Kinase CDC7.AA S_TKc 52-559 13 9.2e-59 202.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 52-559
Range on HMM: 1-231/231
Sequence Identity: 13% (73 aa)

FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEH--ESFLDILNS-------
..| .|||.|.|..||...        .. |.| .       .|  |.|.|    . .|.  |...|.  ||. . | |...   . .|.. .       
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLAQGTRDTKIELLKFVQSEAQQEDCSRNKYHGVVGHKGLLSRPAPKTV
  ..  ..| ||| .. ||. .|. ||.|||.||.| | ..      . |||||                                              
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------------------------------------------

DQQCTPKTSVKRSYTQVHIKQGKDGKERSVGLSVQRSVFGERNFNIHSSISHESPAEKLIKQSKTVDIISRKLATKKTAISTKAMNSVMRETARSCPAVL
                                                                                                    
----------------------------------------------------------------------------------------------------

TCDCYGSDRVCSVCLSRRQQVAPRAGTPGFRAPEVLTKCPDQTT-AIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVL
                         ||| ..|||||      .. ..|.|| |.|.  .|.|. ||.    .. .. ...                    
---------------------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------------

CSKEVPAQDLRALCERLRGLDSTTPRSASGPPGNASYDPAASKNTDHKASRVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLLDKL
                                                                                         ..|| |...|.
-----------------------------------------------------------------------------------------SPEAKDFIRKC

LDLNPASRITAEAALL-------HAFF
|. .|. |.||  ||        | .|
LQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDC7.AA CMGC 371-559 14 8.2e-25 77.68 In-house 292-513 (513) Show / Hide 
Range on Protein: 371-559
Range on HMM: 292-513/513
Sequence Identity: 14% (41 aa)

RAPEVLTKCPDQT---------TAIDMWSAGVIFLSLLSG-------RYPFYK-----------ASDDLTALAQIMTIRG------------------SR
||||.|  ... |         |.|||||.| ||  .. |       ..|. .            ....  |..|. . |                  ..
RAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEE

ETIQ-------------------------AAKAFGKSVLCSKEVPAQDLRALCERLRG---------LDSTTPRSASGPPGNASYDPAASKNTDHKASRV
| ..                          |. . .| .  ...| .... |. ...           . ..  . .                       
EWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVF-NW-IY-E-----------------------

QAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVP--------------DEAYDLLDKLLDLNPASRITAEAALLHAFF
                                    ..              ..| |||.|.| ..|. ||||| || | .|
----------------------------------EKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDC7.AA CAMK 366-559 16 5e-23 70.41 In-house 281-425 (425) Show / Hide 
Range on Protein: 366-559
Range on HMM: 281-425/425
Sequence Identity: 16% (38 aa)

GTPGFRA-PEVLTK-------------CPDQTTAIDMWSAGVIFLSLLSGRYPFYKAS--DDLTALAQIMTIRGSRETIQAAKAFGKSVLCSKEVPAQDL
|||.. | |||| .              |  . ..||||.|||   .|.|..|||  .  ...  . .                                
GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E-W------------------------------

RALCERLRGLDSTTPRSASGPPGNASYDPAASKNTDHKASRVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSN-----SEGWDS---------VPDEAYDL
                                              .  ..  |...   | .. | .  |.     .. |..         | .|. ||
----------------------------------------------IGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDL

LDKLLDLNPASRITAEAALLHAFF
. |.|  .|  |.|.| .| | ..
IRKMLQVDPEKRMTIEQCLNHPWM
Kinase CDC7.AA CK2 52-194 29 6.5e-23 64.58 In-house 1-143 (288) Show / Hide 
Range on Protein: 52-194
Range on HMM: 1-143/288
Sequence Identity: 29% (43 aa)

FKIKDKIGEGTFSSVYLATAQLQEGHEEKI--ALKHLIPTSHPMRIAAELQCLTVAGGQDNVMGLKYCFRKNDHVVI--AMPYLEHESFLDILNSLSFQE
...  ||| | .| |. .        .||.    | | |     .|  |.. |.   |  |.. |    .  .  |     .| .   |  .   |.  .
YEVIRKIGRGKYSEVFEGINIKN---NEKCKIVIKILKPVKK-KKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYD

VREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLA
.| ||..|  ||   |  ||.||||||.| . . . .|  |.| |||
IRYYMFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLA
Kinase CDC7.AA Ciliate-E2 52-195 17 2e-22 73.76 In-house 1-204 (365) Show / Hide 
Range on Protein: 52-195
Range on HMM: 1-204/365
Sequence Identity: 17% (38 aa)

FKIKDKIGEGTFSSVYLATAQLQEGHE----------------------------EKIALKHLIPTSHPM--------RIAAELQCLTVAGGQDNVMGLK
.|.  |||.|.|.|||...  ..   .                            .|  ....    | |        .|  |.. |      .|.. ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLN-HPNIIKMY

YCFR--KNDHVVIAMPYLEHESFLDILN--------------SLSFQEVREYMYNLFV---------------ALKRIHQFG-IVHRDVKPSNFLYNRRL
.||   ..... . | |... . .|...              ... .|....|. ..                ||. .|. . |.||| ||.| |.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

KKYALVDFGLAQ
    ..||||..
--IKIIDFGLSK
Kinase CDC7.AA Ciliate-E2 365-559 16 6.4e-22 72.01 In-house 248-365 (365) Show / Hide 
Range on Protein: 365-559
Range on HMM: 248-365/365
Sequence Identity: 16% (36 aa)

AGTPGFRAPEVLTKCPD--------QTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKAFGKSVLCSKEVPAQDLRALCERL
.||||. |||.| . ..         ....|.||.|||.  .|.|..||                                                   
CGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------------------------------------------------

RGLDSTTPRSASGPPGNASYDPAASKNTDHKASRVQAAQAQHSEDSLYKRDNDGYWSHP-----KDCTSNSE-----GWDSVPDEAYDLLDK----LLDL
                                               ..   .. .. |     || |   .      |.....|. ||. |    .|. 
-----------------------------------------------QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQK

NPASRIT-AEAALLHAFF
.|  ||| .| .| | .|
DPEKRITGWEQILNHPWF
Kinase CDC7.AA CMGC 52-194 16 4.4e-21 65.19 In-house 1-251 (513) Show / Hide 
Range on Protein: 52-194
Range on HMM: 1-251/513
Sequence Identity: 16% (43 aa)

FKIKDKIGEGTFSSVYLATAQLQEGH-----------EEKIALK-----HLIPTS---------HPMRIAAELQCLTVAG----------------GQDN
..| .||||||.. || .. .. ..            .|..|.|     .  ..           |.|.  |...|                       |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VMGLKYCFRKND-----------------HVVIAMPYLEH--ESFLDI----------------------------LNSLSFQEVREYMYNLFVALK--R
. .|...|. ..                 |. . . |..|    ...                               ...   .| ||| .. .||   
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

IHQFG--IVHRDVKPSNFLYNRRLKKY-------------------ALVDFGLA
.|. .  |.||| ||.| | | . . .                    . |||||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase CDC7.AA Pkinase 52-194 25 3.7e-20 72.35 Pfam 1-159 (293) Show / Hide 
Range on Protein: 52-194
Range on HMM: 1-159/293
Sequence Identity: 25% (42 aa)

FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPM--RIAA----ELQCLTVAGGQDNVMGLKYCFRKNDHVVIAMPYLEHE----SFLDILN
..|. |||.|.|..||... .  .    . |.| .   .  .  ....    |.| .    . .|.  |...|. .||. . |.|.|.     .  |.. 
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

-----SL--SFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKK---YALVDFGLA
     ..  | .|.. ||| .. .|. .|. ||.|||.||.|.|....        . |||||
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA
Kinase CDC7.AA Ciliate-E2-Unclassified 364-559 16 5.9e-19 62.4 In-house 222-352 (352) Show / Hide 
Range on Protein: 364-559
Range on HMM: 222-352/352
Sequence Identity: 16% (37 aa)

RAGTPGFR----APEVLTKCPDQT---TAIDMWSAGVIFLSLLSGRYPFYKASDDL---------------TALAQIMT--IRGSRETIQAAKAFGKSVL
..|||..     ||||| ..   .    ..|.|| |||.  .| |.||||  ...                  . .|.   |  . .  |          
FCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQ---------

CSKEVPAQDLRALCERLRGLDSTTPRSASGPPGNASYDPAASKNTDHKASRVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLLD--
                                                                                      . ...|| |..   
------------------------------------------------------------------------------------IPKHWSPEAKDFINDL

--KLLDLNPASRITAEAALLHAFF
  |.|. || .|||.| .| | .|
LQKMLKKNPNKRITFEQILNHPWF
Kinase CDC7.AA Ciliate-E2-Unclassified 52-194 18 3.7e-18 59.61 In-house 1-194 (352) Show / Hide 
Range on Protein: 52-194
Range on HMM: 1-194/352
Sequence Identity: 18% (36 aa)

FKIKDKIGEGTFSSVYLATAQLQ-------EGHEEKIALKHLIPTSHPMRIAA--ELQCLTVAGGQD----------------NVMGLKYCFRKNDHVVI
.||  .||.| |..||..    |       . .  .|  ...| ...   .    |....     |.                ... . |||.. ... |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

AMPYLEHESFLDILNS--------------------LSFQEVR-----EYMYNLFVALKRIHQFG-IVHRDVKPSNFLYNRRLK--KYALVDFGLA
 | |.|. . ......                    .. |...      |.. . ..|. .|. . |.||| ||.| |..   |  .  . |||..
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS
Kinase CDC7.AA CAMK 57-195 14 1.4e-16 49.27 In-house 1-244 (425) Show / Hide 
Range on Protein: 57-195
Range on HMM: 1-244/425
Sequence Identity: 14% (36 aa)

KIGEGTFSSVYLATAQLQEGHE---------EKIALKHLIPTSHP------------------------------MRIAAELQCLTVAGG------QDNV
..|.|.|. |.|..  .  | |         .| | | .  . ..                               ..  |....    |        |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

MGLKYCFRK-------------------NDHVVIAM---PYLEHE----SFLDILNS------------------LSFQEVREYMYNLFVALKRIHQFGI
  |   .                     ..|... |    | .        .| . .                  .. .|.| |.  .  |.. .|. .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDVKPSNFLYNRRL----------------KKYALVDFGLAQ
|||| || | |.. .                  .  ..|||.|.
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFAN
Kinase CDC7.AA Pkinase 364-419 33 6e-14 50.4 Pfam 171-231 (293) Show / Hide 
Range on Protein: 364-419
Range on HMM: 171-231/293
Sequence Identity: 33% (21 aa)

RAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKAS------DDLTALAQIM
..|||...||||. .... ....||||.|.|.  .|.|| ||.  .      |..  ...||
FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDNHDQMQMICRIM
Kinase CDC7.AA Ciliate-E2a 525-559 42 1.6e-13 36.23 In-house 241-275 (275) Show / Hide 
Range on Protein: 525-559
Range on HMM: 241-275/275
Sequence Identity: 42% (15 aa)

WDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFF
|  ...|..||. |.|. .|  ||||. || | .|
WEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CDC7.AA Ciliate-E2a 363-406 46 2.2e-13 35.78 In-house 169-217 (275) Show / Hide 
Range on Protein: 363-406
Range on HMM: 169-217/275
Sequence Identity: 46% (23 aa)

PRAGTPGFRAPEVLTKCPD---Q---TTAIDMWSAGVIFLSLLSGRYPFY
.. ||||. ||||| . ..   .   .|  ||||.||||  ||.|. ||.
QKCGTPGYVAPEVL-NNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFK
Kinase CDC7.AA CDK 478-559 20 3.2e-13 38.48 In-house 250-284 (284) Show / Hide 
Range on Protein: 478-559
Range on HMM: 250-284/284
Sequence Identity: 20% (17 aa)

PAASKNTDHKASRVQAAQAQHSEDSLYKRDNDGYWSHPKDCTSNSEGWDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFF
|  .|  |.                                               |||.|.| ..|. ||.||.|| | .|
PGVTKLPDY-----------------------------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDC7.AA GSK 146-182 40 6.9e-12 32.0 In-house 116-152 (328) Show / Hide 
Range on Protein: 146-182
Range on HMM: 116-152/328
Sequence Identity: 40% (15 aa)

QEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRR
.... ||| .| .|. .| .||.|||.||.| |....
IHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPD
Kinase CDC7.AA CK2 521-559 38 1.5e-11 29.96 In-house 250-288 (288) Show / Hide 
Range on Protein: 521-559
Range on HMM: 250-288/288
Sequence Identity: 38% (15 aa)

NSEGWDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFF
..|  . . .|| |.|||.|   .. ||||  |. |..|
HQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase CDC7.AA CAMK1 525-559 33 3.1e-11 28.84 In-house 241-276 (276) Show / Hide 
Range on Protein: 525-559
Range on HMM: 241-276/276
Sequence Identity: 33% (12 aa)

WDSVPDE-AYDLLDKLLDLNPASRITAEAALLHAFF
||.. |. | |.. ..|...|  |.|.| .| | ..
WDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CDC7.AA Ciliate-E2a 146-195 35 3.4e-11 29.22 In-house 101-157 (275) Show / Hide 
Range on Protein: 146-195
Range on HMM: 101-157/275
Sequence Identity: 35% (20 aa)

QEVREYMYNLF-VALKRIHQFGIVHRDVKPSNFLYN---RR---LKKYALVDFGLAQ
||....| .|.  .|  .|| .|.||| || |.|..        ...  ..|||||.
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLAT
Kinase CDC7.AA CAMK1 364-406 51 4.1e-11 28.48 In-house 173-217 (276) Show / Hide 
Range on Protein: 364-406
Range on HMM: 173-217/276
Sequence Identity: 51% (23 aa)

RAGTPGFRAPEVLTK--CPDQTTAIDMWSAGVIFLSLLSGRYPFY
. ||||. |||||.         |.||||.|||.  || |  |||
ACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFY
Kinase CDC7.AA CK2 364-426 26 2.3e-10 26.37 In-house 155-217 (288) Show / Hide 
Range on Protein: 364-426
Range on HMM: 155-217/288
Sequence Identity: 26% (17 aa)

RAGTPGFRAPEVLTKCPDQTTAIDMWSAGVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRE
| ..  ...|| |    .   ..|||| |..| |..  . ||.. .|  ..| .|... |  .
RVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGHDNYDQLVKIVKVLGTED
Kinase CDC7.AA Pkinase 513-559 25 1.4e-09 34.96 Pfam 251-293 (293) Show / Hide 
Range on Protein: 513-559
Range on HMM: 251-293/293
Sequence Identity: 25% (12 aa)

SHPKDCTSNSEGWDSVPDEAYDLLDKLLDLNPASRITAEAALLHAFF
.| . .. ...  . ...|. |.....|...|..|.||| .| | .|
RH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CDC7.AA GSK 519-559 28 2.6e-09 23.96 In-house 287-328 (328) Show / Hide 
Range on Protein: 519-559
Range on HMM: 287-328/328
Sequence Identity: 28% (12 aa)

TSNSEGWDSVPDE-AYDLLDKLLDLNPASRITAEAALLHAFF
| .   |   ... ..||. |.|  .| .|...  |..| ||
TVYMFKWCHTDMQDWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase CDC7.AA CDK 124-194 30 2.6e-08 22.51 In-house 93-160 (284) Show / Hide 
Range on Protein: 124-194
Range on HMM: 93-160/284
Sequence Identity: 30% (24 aa)

VVIAMPYLEHE--SFLDILNSLSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRR-------LKKYALVDFGLA
... ..|..|   ...|         .. ||. |  .|  .|. .|.||| ||.| |.|..       ||   . |||||
LYMVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLK---IADFGLA
Kinase CDC7.AA CAMK1 52-70 47 3.1e-08 19.99 In-house 1-19 (276) Show / Hide 
Range on Protein: 52-70
Range on HMM: 1-19/276
Sequence Identity: 47% (9 aa)

FKIKDKIGEGTFSSVYLAT
......||.|.|| |||.|
YEFGKEIGRGAFSEVYLCT
Kinase CDC7.AA Ciliate-E2a 52-70 57 3.8e-08 20.1 In-house 1-19 (275) Show / Hide 
Range on Protein: 52-70
Range on HMM: 1-19/275
Sequence Identity: 57% (11 aa)

FKIKDKIGEGTFSSVYLAT
.|...|||.|.| |||||.
YKFIKKIGKGNFGSVYLAQ
Kinase CDC7.AA CDK 371-405 37 3.2e-07 18.97 In-house 186-225 (284) Show / Hide 
Range on Protein: 371-405
Range on HMM: 186-225/284
Sequence Identity: 37% (15 aa)

RAPEVLTKCPDQT--TAIDMWSAGVIFLSLLS---GRYPF
||||.|  . . .  |.|||||.| ||  ..    ... |
RAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF
Kinase CDC7.AA TyrKc 52-261 14 4.8e-07 -108.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 52-261
Range on HMM: 1-280/280
Sequence Identity: 14% (42 aa)

FKIKDKIGEGTFSSVYLATAQLQEGHEEKIALKHLIPTSHPMRIAAELQCLTVAG-GQDNVMGLKYCFRKN-------DHVVIAMPYLEHESFLDIL--N
 . ..|.||| |  ||..|.       .. | | | . .  . .  |.. ..  |   .|.  |  . ..        . . | | | .| . .| |  .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

S--LSFQEVREYMYNLFVALKRIHQFGIVHRDVKPSNFLYNRRLKKYALV---DFGLAQGTRDT---------KIE----LLK------------FVQS-
   |. ..  ....        .|. ...|||    | |.....     |   ||||.    |          .        |            .  . 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

---------------------EAQQED-----CSRNKYHGVVGHKGLLSRPAP--------KTVD-----QQCTPKTSVKR-SYTQVHIKQ
                     .   ..     .|    .  | . . . .|.          . .     .||      .| . ...| . 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CDC7.AA GSK 52-84 26 2e-06 14.86 In-house 1-38 (328) Show / Hide 
Range on Protein: 52-84
Range on HMM: 1-38/328
Sequence Identity: 26% (10 aa)

FKIKDKIGEGTFSSVYLATAQLQEGHEEKI-----ALK
......|| |.|. || |...    ....|     | |
YEEMKVIGHGSFGVVYQAYMNSPSNETKEIWLGPVAIK
Kinase CDC7.AA CDK 52-84 34 3e-06 15.63 In-house 1-35 (284) Show / Hide 
Range on Protein: 52-84
Range on HMM: 1-35/284
Sequence Identity: 34% (12 aa)

FKIKDKIGEGTFSSVYLATAQLQEG--HEEKIALK
... .||||||.  || |  ... .   .. .|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALK
Kinase CDC7.AA CAMK1 162-195 43 4e-06 13.8 In-house 124-161 (276) Show / Hide 
Range on Protein: 162-195
Range on HMM: 124-161/276
Sequence Identity: 43% (17 aa)

IHQFGIVHRDVKPSNFLYNRR-----LKKYALVDFGLAQ
.|. |||||| || | ||        .|.  . ||||..
MHSKGIVHRDLKPENLLYYDKDEDSKIKR-SIADFGLSK
Kinase CDC7.AA GSK 371-392 50 2.3e-05 11.7 In-house 185-206 (328) Show / Hide 
Range on Protein: 371-392
Range on HMM: 185-206/328
Sequence Identity: 50% (11 aa)

RAPEVLTKCPDQTTAIDMWSAG
|||| . .| . |..||.||.|
RAPELIFGCTNYTCQIDVWSCG
Kinase CDC7.AA Pkinase_Tyr 52-84 29 0.000104 16.57 Pfam 1-34 (270) Show / Hide 
Range on Protein: 52-84
Range on HMM: 1-34/270
Sequence Identity: 29% (10 aa)

FKIKDKIGEGTFSSVYLATAQ-LQEGHEEKIALK
 ..  |.||| | .||..|.  ...... . | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK