B0218.5

Species: Nematode worm
Alias: aSWK129, CE06688, B0218.5
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 8156434-8155241, WormBase Genetic Map location: IV:3.66,

Classification

Group: CK1
Family: Worm6

Sequence

Name Sequence Type Origin Length Description Download
B0218.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 289 Kinase domain by global Sugen HMM Fasta, JSON
B0218.5.AA Protein Genbank 367 None Fasta, JSON

Protein domain

Protein domains of B0218.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase B0218.5.AA Worm6 24-292 47 1.4e-160 539.72 In-house 1-279 (279) Show / Hide
Range on Protein: 24-292
Range on HMM: 1-279/279
Sequence Identity: 47% (132 aa)

YKVLALLGKGGYGAVYSVLRLSDME--KFAIKCEN--AAACRKALYMDCNVLKGAAKIQSRHFCTVIDQAAVKNR-FNFIVMKLIGKNLWDLRMDTAECR
.||....|.||.||||.|.. ||..  .||.|||.  . ..|. |.|.|.||| ......||||...|.. |.|| ||.|||.|.||||||||.......
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FTKGTSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGR---KESNEHHTIFMLDFGLCREFVKRGEGR-LRTQR-AKSQFRGTTRYAPINSMLEIDTGR
|. ||.|| |.|||..||.||..||.|||.|||||..||   ||.||||||.|||||.||.......|  |||.| .. .||||.||||....  .. .|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

KDDIESWLYMVAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEIMADLFYNCPLKEFERILKYVDELDFYSEPDYKFV
|||.|||.||..|...|.||||..|.. .....|.... ||....|...| .|| .||..|..|.|.......|||||.
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI

Kinase B0218.5.AA CK1 24-292 29 1.9e-109 369.89 In-house 1-339 (339) Show / Hide
Range on Protein: 24-292
Range on HMM: 1-339/339
Sequence Identity: 29% (100 aa)

YKVLALLGKGGYG-AVYSV-----LRLSDM-----EKFAIKCENA-AACRKALYMDCNVLKGAAKIQ---------SRHFCT----------VIDQAAVK
.||  ..|.||.| ..| |      ....      |..|.|.| . ..... . |.. ... . . .         ..|||.          ...   ..
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

NRFNFIVMKLIGKNLWDLRM-DTA-ECRFTKGTSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKES-----------NEHHTIFMLDFGLCR-EFV
...|..|| | |.||.|||. ..    .|...|.|. | |.| ..|..|. ||.||||||.||..||.||           |||....|.|||..|  ..
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

KRGEGR-----------LRTQRA---KSQFRG-TTRYAPINSMLEIDTGRKDDIESWLYMVAEWTSGG--LPWRKFKATER----EKVLKYKKDVRTD-K
......           .|..|    | .||| |.||..||..| .. ||.||..||.||..||. |.  |||.. |. ..    . | | |.. ... |
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQ-VEKMKYEFIDEKK

EIMADLFYNCPLK------EFERILKYVDELDFYSEPDYKFV
  . .. ..||.|      ||  |.||...|..|..|||...
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI

Kinase B0218.5.AA TTBKL 24-296 30 5.2e-66 221.85 In-house 1-288 (288) Show / Hide
Range on Protein: 24-296
Range on HMM: 1-288/288
Sequence Identity: 30% (91 aa)

YKVLALLGKGGYGAVYSVLRLSDMEKFAIKCE--NA-AACRKALYMDCNVLKGAAKIQSRHFCTVIDQAAVKNRFNFIVMKLIGKNLWDLRMDTAECR-F
...  ..|.||.|.|| |  ..| ...|.. |  |  .   . . |  .||.  ..  |.||......   . ..||.|| | |.|| |||..    . |
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGK-RKDYNFMVMTLCGPNLQDLRKMMPNKKRF

TKGTSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESN--EHHTIFMLDFGLCREFV-KRGEG---------RLRTQRA---KSQFRGTTRYAPIN
..||..  . ||| .. ..|. ||.|||.||.|...| ....  . .... .|||..| .. | ||.         ..|..|    |..|||||||. .|
SDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPN

SMLEIDTGRKDDIESWLYMVAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEIMADLFYNCP-----LKEFERILKYVDELDFYSEPDYKFVYCCL
  .  . ||.||. ||.||..|   | |||.  .  ..... . ||.      .. |||...|      .||. . |.. .|..|..|||  .| |.
MHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNME--DKMEIEHMKKNM-----KDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF

Kinase B0218.5.AA TTBK 24-292 39 1.8e-64 220.52 In-house 1-257 (257) Show / Hide
Range on Protein: 24-292
Range on HMM: 1-257/257
Sequence Identity: 39% (106 aa)

YKVLALLGKGGYGAVYSVLRLSDM-EKFAIKCENAAACRKALYMDCNVLKGAAKIQSR-HFCTVIDQAAVKNRFNFIVMKLIGKNLWDLRMDTAECRFTK
 ||..  | ||.| .|. . .    |. ||| | | . .  | |   |||   | | . | |  |      ..||..||.| |||| |||    .  |. 
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLK---KLQGCDHVCRFI-GCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSL

GTSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRYAPINSMLEIDTGRKDDIESWL
.| |.   | | |||. |  ||||||||| |||.||  |.   . .|||||| | ..  ..|  |. |.   |||| ||| ||. .  . ||.||  |  
STTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKC-YMLDFGLARQYTN-ACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLF

YMVAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEIMADLFYNCPLKEFERILKYVDELDFYSEPDYKFV
||  |   | ||||| |  .    .| | | |       .|  .|| .||.  .. .  |..   |||...
YMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHR-------MLLKHCP-HEFHQFMDHIKSLNYEDRPDYQLI

Kinase B0218.5.AA Dual 24-296 28 1.6e-41 137.34 In-house 1-282 (282) Show / Hide
Range on Protein: 24-296
Range on HMM: 1-282/282
Sequence Identity: 28% (81 aa)

YKVLALLGKGGYGAVYSVLRLSD----MEKFAIKCENAAACRKALYMD--CNVLKGAAK-------IQSRHFCTVIDQ-AAVKNRFNFIVMKLIGKNLWD
 ||  ||| || . || | | |      .....| |     .  |  .    | . .|           ..|   .|    .. . ...|| . |  | .
WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQE

LRMDTAECRFTKGTSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRYAPINSMLEI
 |  .    ... .|   | | | .|  ||  |.|||.||| ||..|  .  .  |..|.||.. | ..    .  || | |  . |. ||| .  |.. 
IRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGM--DETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQK

DTGRKDDIESWLYMVAEW--TSGGLPWRKFKATEREKVLKYKKDVRTDKEIMADLFYNCPLKEFERILKYVDELDFYSEPDYKFVYCCL
| |||||.|.| |||      . |..||  |  .. ...| |    . .       |   ....  .. ||. . . | |||     ||
DQGRKDDLECWIYMVFDLMDPEHGMSWR--KECDCNMMIKQKDNFMYHFDKHQ---YSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL

Kinase B0218.5.AA CK1-Unique 24-223 29 4.8e-39 132.99 In-house 1-219 (337) Show / Hide
Range on Protein: 24-223
Range on HMM: 1-219/337
Sequence Identity: 29% (66 aa)

YKVLALLGKGGYGAVYSVLRLSDM------EKFAIKCENAAACRK--ALYMDCNVLKGAAKIQ-----SRHFCTVIDQAAVKNRFNFIVMKLIGKNLWDL
..| ...|.|||| |. |  . .        ... | |  .. .    |    ||.|.  |       .|||| |.|   .     .||| ..|...  .
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHD-FHQHRDWWWIVMTMHGPSMEEC

RMDTAECRFTKG------TSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCRE--FVKRGEGRLRTQRAKSQFRGTTRYAP
.|  .   ||..      . .. . |||  ||  |  ||.||..||.|.  .     . |...|||.| ||   ||    . .|  | .  |||. .|.|
CMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNN-HQIRQPRPITPFRGCKDYCP

INSMLEIDTGRKDDIESWLYM
. . .. . ||.|| |||.||
CSCHQCREHGRRDDMESWFYM

Kinase B0218.5.AA CK1-A 24-292 30 3.7e-34 118.02 In-house 1-261 (261) Show / Hide
Range on Protein: 24-292
Range on HMM: 1-261/261
Sequence Identity: 30% (81 aa)

YKVLALLGKGGYGAVYSVLRLSDMEKFAIKCENAAACRKALYMDCNVLKGAAKIQSRHFCTVIDQAAVKNRFNFIVMKLIGKNLWDLRMDTAECRFTKGT
|...  .| | .| .|  . . . |  ||| | . |    |  .  | .    .|       .        .| .|| |.|  | ||     . |||  |
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYR---ILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDL-FNFCKRRFTMKT

SLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRYAPINSMLEIDTGRKDDIESWLYM
 |  | | .  || .|  .|.|||||| || .|      .  .|..|||| . .      .    |   .  || ||| ||  | |.  |.||.||  |.
VLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNK--LFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYV

VAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEIMADLFYNCPLKEFERILKYVDELDFYSEPDYKFV
.  .  | |||  .||    |  || |       .  .        ||  ...|. .| |  .||| ..
MMYFNRGKLPWQGMKAM--TKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL

Kinase B0218.5.AA CK1-D 24-292 28 4.4e-30 103.26 In-house 1-261 (261) Show / Hide
Range on Protein: 24-292
Range on HMM: 1-261/261
Sequence Identity: 28% (77 aa)

YKVLALLGKGGYGAVYSVLRLSDMEKFAIKCENAAACRKALYMDCNVLKGAAKIQSRHFCTVIDQAAVKNRFNFIVMKLIGKNLWDLRMDTAECRFTKGT
|..   .| | .| .|    ..  |  ||| | . .    | ..  . |    .|       |        .| .|| |.|  | ||     . .|   |
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYK---MMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDL-FNYCHRKFSLKT

SLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRYAPINSMLEIDTGRKDDIESWLYM
 |  | | .  || .|   |.|||||| || .|       ......|||| . .      .    | . .  || ||| ||  . |.  |.||.||  |.
VLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGL--GKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYV

VAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEIMADLFYNCPLKEFERILKYVDELDFYSEPDYKFV
.  .  | |||   ||.   |  || . .    ..  |   .   .||.. . |. .| |   ||| ..
LMYFNRGSLPWQGLKAA--TKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL

Kinase B0218.5.AA CK1-G 95-292 31 8.9e-27 87.71 In-house 70-266 (266) Show / Hide
Range on Protein: 95-292
Range on HMM: 70-266/266
Sequence Identity: 31% (64 aa)

FNFIVMKLIGKNLWDLRMDTAECRFTKGTSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQF
.| .|| | |  | ||  |  . .|.  | .  | | .  .|..|    . ||.|| || .||. ....|.|.. |||. ....    ..    | .   
YNIMVMDLLGPSLEDL-FDWCDRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSL

RGTTRYAPINSMLEIDTGRKDDIESWLYMVAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEI-MADLFYN--CPLKEFERILKYVDELDFYSEPDYKF
 || ||  ||  |     | ||.|.   |      | |||   ||      ..|.|   | ... . ||  |   | ..| . |.|| .|||  .||| .
TGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNK--ERYQKIGDTKRKTNIEDLCQNNAFP-EQFATYLRYVRRLDFFECPDYDY

V
.
L

Kinase B0218.5.AA CK1 135-219 40 2.5e-18 59.84 In-house 118-201 (271) Show / Hide
Range on Protein: 135-219
Range on HMM: 118-201/271
Sequence Identity: 40% (34 aa)

IEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRYAPINSMLEIDTGRKDDIES
|| .|  .|.|||||| || .||   ...|.... ||||  ....  ...   .| .  . ||.||| ||. | |  .|.|| ||
IEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMES

Kinase B0218.5.AA S_TKc 24-311 15 2.3e-12 4.38 SMART 1-231 (231) Show / Hide
Range on Protein: 24-311
Range on HMM: 1-231/231
Sequence Identity: 15% (49 aa)

YKVLALLGKGGYGAVYSVLRLSDMEKFAIKCENAAACRKALYMDCNVLKGAAKIQSRHFCTVIDQAAVKNRFNFIVMKLIGK---NLWDLRMDTAE----
|..| ..|||..| || .   .. ...|||. .     . ..   ..||     .  . .. .|       . ..|| ...    .| |.  .       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

CRFTKGTSLKAASQCLISIEELHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRYAPINSMLEIDTGRKDD
..|.  .  . . | .  .| .|. |..|||.|| |  . .       .|   ||||.|..              . | ||  | .   .          
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL--------------TTFCGTPWYMAPEVL----------

IESWLY----------MVAEWTSGGLPWRKFKATEREKVLKYKKDVRTDKEIMADLFYNCPLKEFERILKYVDELDFYSEPDYKFVYCCLQHAAA----A
  .. .          ...|  .|  |..     . ....|  .                                  |..   |.  |||   .    |
--GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA

SKIKD-------TDPL
 ..            .
-EALQDEWDIKCHPWF

Kinase B0218.5.AA Pkinase 24-54 25 6e-06 22.03 Pfam 1-31 (293) Show / Hide
Range on Protein: 24-54
Range on HMM: 1-31/293
Sequence Identity: 25% (8 aa)

YKVLALLGKGGYGAVYSVLRLSDMEKFAIKC
|...  .|.|..| ||   . .. ...|.|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI

Kinase B0218.5.AA CK1 269-290 40 0.000356 10.5 In-house 250-271 (271) Show / Hide
Range on Protein: 269-290
Range on HMM: 250-271/271
Sequence Identity: 40% (9 aa)

KEFERILKYVDELDFYSEPDYK
.|| . |.|.  |.|. .|||.
NEFAMYLNYCRQLHFEEKPDYM

Kinase B0218.5.AA CK1 24-59 28 0.001208 8.65 In-house 1-38 (271) Show / Hide
Range on Protein: 24-59
Range on HMM: 1-38/271
Sequence Identity: 28% (11 aa)

YKVLALLGKGGYGAVYSVLRLSDMEK--FAIKCENAAA
|.|   .| |  | .| . .....|.   ||| | . .
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKS

Kinase B0218.5.AA Pkinase 138-202 26 0.002057 13.15 Pfam 124-179 (293) Show / Hide
Range on Protein: 138-202
Range on HMM: 124-179/293
Sequence Identity: 26% (17 aa)

LHRFGFLHRDIKPGNFAVGRKESNEHHTIFMLDFGLCREFVKRGEGRLRTQRAKSQFRGTTRYAP
.|. |..|||.|| |. . ..  ..  ..   ||||.. |       .  ..  . | || .|..
CHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMA