C09B9.4

Species: Nematode worm
Alias: C09B9.4, aSWK145, CE06796
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: IV: 5033364-5031617, WormBase Genetic Map location: IV:1.47,

Classification

Group: CK1
Family: Worm6

Sequence

Name Sequence Type Origin Length Description Download
C09B9.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
C09B9.4.AA Protein Genbank 359 None Fasta, JSON

Protein domain

Protein domains of C09B9.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C09B9.4.AA Worm6 29-289 34 3.5e-133 448.74 In-house 1-279 (279) Show / Hide
Range on Protein: 29-289
Range on HMM: 1-279/279
Sequence Identity: 34% (95 aa)

YKMCDSIATGPFSSVFLVEK--DGI--PYAMKVESQ-SKCLRPVLKLDHAVLRALGHQS--GFPSLTSAGRTEN--FKYVVMQLVGPDLSMLLEFAPQQR
.|..  |..|.|..|..||.  |.   ..|||.|.|  .. |..||....|| |..|.   .|.... .|...|  |.|.||.|||..|..| ...|...
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVGL-----GEESSIVYMLDFGLTR--KYLEHNGSRSLLR-PHGPSVGTFPYAPLASLGFCDQSP
|. .| .|||.|.|.....|| .|...||||..||..|       .|....||||||..|  ||.......   | .. ...||..|||||.  ...|..
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

IDDIEGWLYMIVHLLKGGLPWHNSKRALNLPKVREWKMYCRRPGGKHYLFAGIPK-GWADIFDVIVNTAPHETPDYNKI
 ||.|.|.||.|....|.|||...|.  .  |...|.....|.......|...|| .. ||.|.| ... ...|||..|
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI

Kinase C09B9.4.AA CK1 29-289 22 2.6e-83 283.06 In-house 1-339 (339) Show / Hide
Range on Protein: 29-289
Range on HMM: 1-339/339
Sequence Identity: 22% (76 aa)

YKMCDSIATGPFS-SVFLV------EKDG------IPYAMKVESQSKCLRPVLKLDHAVLRALGHQS-----------GFPS----------LTSAGRTE
.|    |..| |   ...|       ...        ||||||. .   .. .... ... .. ..            .|..          .  .|...
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

N-FKYVVMQLVGPDLSMLLE--FAPQQRFTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVGL-------------GEESSIVYMLDFGLTR-KYL
. ..|.||.|.||.|. |..  . ....|. .|...||.|.|..|...|..|.. ||.|..||..|.             ..|. .|||.|||. | ||.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

EHNGSR------------SLLRP---HGPSVG-TFPYAPLASLGFCDQSPIDDIEGWLYMIVHLLKGG--LPWHNSKRALNLPK---VREWKMYCRRPGG
. .|..               |.   . . .| |. |.....   ..|.. ||.. |.||....|||.  |||.| |.  .  |   |...|. ...   
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKP-KDHQVEKMKYEFIDEKK

KHYLF--------AGIPKGWADIFDVIVNTAPHETPDYNKI
....|        ...|. . .|...| .  ....||| .|
MSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI

Kinase C09B9.4.AA TTBKL 29-182 28 1.5e-38 127.78 In-house 1-165 (288) Show / Hide
Range on Protein: 29-182
Range on HMM: 1-165/288
Sequence Identity: 28% (47 aa)

YKMCDSIATGPFSSVF--LVEKD-GIPYAMKVESQS-KCLRPVLKLDHAVLRALG--HQSGFPSLTSAGRTENFKYVVMQLVGPDLSMLLEFAPQQR-FT
..   .|. | | .|.   . || .  .|||.|...      ..|. . || .|   ... || .  .|..... ..||.|.||.|. |    |... |.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

SSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVGLGEE----SSIVYMLDFGLTRKYLEHNGS
 .|.. |. |.|. |. .|..|.. |||| .|...|. ..    . .|| .|||..|.|....|.
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGE

Kinase C09B9.4.AA Dual 97-293 28 7.9e-33 107.63 In-house 87-282 (282) Show / Hide
Range on Protein: 97-293
Range on HMM: 87-282/282
Sequence Identity: 28% (56 aa)

KYVVMQLVGPDLSMLLEFAPQQRFTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVGLGEESSIVYMLDFGLTRKYLE-HNGSRSLLRPHGPSVGT
||.|| ..|| |   .  .    .. .. . .|.|.|. .. || .|.|.|..|  ||..|||.. . |||.||.. |||..  |.     |      |.
KYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGC

FPYAPLASLGFCDQSPIDDIEGWLYMIVHLL--KGGLPWHNSKRALNLPKVREWKMYCRRPGGKHYLFAGIPKGWADIFDVIVNTAPHETPDYNKIANMV
  ||  | ..  ||   ||.| | ||.  |.  . |..| .. . .   |  .  ||    .   . .. ||.. ... ... .     ||||  . |. 
GRYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMY----HFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL





Kinase C09B9.4.AA TTBK 54-232 35 1e-27 95.03 In-house 29-207 (257) Show / Hide
Range on Protein: 54-232
Range on HMM: 29-207/257
Sequence Identity: 35% (63 aa)

AMKVESQSKCLRPVLKLDHAVLRALGHQSGFPSLTSAGRTENFKYVVMQLVGPDLSMLLEFAPQQRFTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQN
|.|||| ..  . |||.  |||. |  .         || ..| |.|||| |  |. |   .|.. |. ||  .. .| |. ..  |. |.| ||.|  |
AIKVES-AQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSN

FAVG-LGEESSIVYMLDFGLTRKYLEHNGSRSLLRPHGPSVGTFPYAPLASLGFCDQSPIDDIEGWLYMIVHLLKGGLPW
||.| . ..  ..||||||| |.|.   |     |.     ||  ||   .    .    ||     || |  ..| |||
FAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPW

Kinase C09B9.4.AA CK1-A 29-289 28 2.8e-27 93.36 In-house 1-261 (261) Show / Hide
Range on Protein: 29-289
Range on HMM: 1-261/261
Sequence Identity: 28% (77 aa)

YKMCDSIATGPFSSVFLV--EKDGIPYAMKVESQSKCLRPVLKLDHAVLRALGHQSGFPSLTSAGRTENFKYVVMQLVGPDLSMLLEFAPQQRFTSSTVY
|..   |  | |  ..|    ..|   |.|.||. |   | |  .  | | |    |.| .   |.  ..  .||.|.|| |  |  |  . |||  || 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESN-KARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFC-KRRFTMKTVL

KIALQTLDRLRVLHEAGWLNRDVKAQNFAVGLGEESSIVYMLDFGLTRKYLEHNGSRSLL-RPHGPSVGTFPYAPLASLGFCDQSPIDDIEGWLYMIVHL
 .| | . |.  .|| ... ||.|  || .|.|     ....||||..|| ...  . .  |     .||  || .      .||  ||.|   |...  
MLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYF

LKGGLPW---HNSKRALNLPKVREWKMYCRRPGGKHYLFAGIPKGWADIFDVIVNTAPHETPDYNKI
 .| |||   .   .     |. | ||          |  | |  .. ..  . |   .|.|||  .
NRGKLPWQGMKAMTKKQKYEKISEKKMSTPI----EQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL

Kinase C09B9.4.AA CK1-D 29-289 26 2.1e-26 90.08 In-house 1-261 (261) Show / Hide
Range on Protein: 29-289
Range on HMM: 1-261/261
Sequence Identity: 26% (70 aa)

YKMCDSIATGPFSSVFLVE--KDGIPYAMKVESQSKCLRPVLKLDHAVLRALGHQSGFPSLTSAGRTENFKYVVMQLVGPDLSMLLEFAPQQRFTSSTVY
|..   |  | |  ... .  . .   |.|.|.  |   | |...  . . .    | |..   |.  ..  .||.|.|| |  |  .  . .|   || 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECI-KTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYC-HRKFSLKTVL

KIALQTLDRLRVLHEAGWLNRDVKAQNFAVGLGEESSIVYMLDFGLTRKYLEHNGSRSL-LRPHGPSVGTFPYAPLASLGFCDQSPIDDIEGWLYMIVHL
 .|.| . |.  .|   .. ||.|  || .|||   ..||..||||...| . .  . .  | .    ||  || .      .||  ||.|   |...  
MLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYF

LKGGLPWHNSKRALNLPK---VREWKMYCRRPGGKHYLFAGIPKGWADIFDVIVNTAPHETPDYNKI
 .| |||   | |    |   . | ||  .     . | .| |. ... ..   |    . |||  .
NRGSLPWQGLKAATKRQKYERICEKKMSTKI----DTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL

Kinase C09B9.4.AA CK1-Unique 29-232 20 5.3e-22 73.09 In-house 1-232 (337) Show / Hide
Range on Protein: 29-232
Range on HMM: 1-232/337
Sequence Identity: 20% (49 aa)

YKMCDSIATGPFSSVFLVEKDGIP--------YAMKVESQSKCLRP--VLKLDHAVLRALGHQS-------GFPSLTSAGRTENFKYVVMQLVGPDLSML
..    |  | .  |  | .   .        |.|| | |.   ..   |.   .|. ..   .        |. .   . .   .. ||...|| .   
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTE-QHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEE-

LEFAPQQ-RFTSS------TVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVGLGE--ESSIVYMLDFGLTRK--YLEHNGSRSLLRPHGPSVGTFPYAP
. ...    || .      .. . ..|.|. ... |..| ..|. |  |.  .     .    ||||.|  |.   .. |..    ||  |  |. .|.|
CCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCP

LASLGFCDQSPIDDIEGWLYMIVHLLKG--GLPW
 .. .  ...  || | |.||..||. .  || |
CSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSW

Kinase C09B9.4.AA CK1 29-177 26 4.7e-18 58.9 In-house 1-160 (271) Show / Hide
Range on Protein: 29-177
Range on HMM: 1-160/271
Sequence Identity: 26% (44 aa)

YKMCDSIATGPFSSVFLVEKDGI-----PYAMKVESQSKCLRPVLKLDHAVLRALGH------QSGFPSLTSAGRT--ENFKYVVMQLVGPDLSMLLEFA
|.    | .| |  ..|..         ..|.|.|.. .   | |.    ... | .        |.| .   |.   ... ..|| | ||.|  |. | 
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSK-HPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFC

PQQRFTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVGL-GEESSIVYMLDFGLTRKYL
 ...|.  ||  || | ..|. ..|. . . ||.|  || .|. | .. .||. ||||  .|.
-NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYR

Kinase C09B9.4.AA CK1-Unclassified 29-182 26 1.3e-16 45.58 In-house 1-166 (244) Show / Hide
Range on Protein: 29-182
Range on HMM: 1-166/244
Sequence Identity: 26% (45 aa)

YKMCDSIATGPFSSVFLVE--KDGIPYAMKVESQSKCLRPVLKLDHAVLRALGHQS-------GFPSLTSAGRT--ENFKYVVMQLVGPDLSMLLEFAPQ
|.  . | .| |  ....   ...  .|.|.|.  .   | |.    ....| . .       |.| .   |.   ... ..|| | ||.|  |. .  .
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMC-N

QRFTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVG-LGEESSIVYMLDFGLTRKYL--EHNGS
..|.  ||  || | ..|. .||. . . || |  || .| || .. .||. ||||  .|.    .|.
RKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGK

Kinase C09B9.4.AA S_TKc 29-316 13 7.4e-10 -32.36 SMART 1-231 (231) Show / Hide
Range on Protein: 29-316
Range on HMM: 1-231/231
Sequence Identity: 13% (41 aa)

YKMCDSIATGPFSSVFLVEK--DGIPYAMKVESQSKCLRPVLKLDHAVLRALGHQSGFPSLTSAGRTENFKYVVMQLVGP---DLSMLLEFAPQQR----
|.. . |  | |..|... .  .|  .|.|. .        ..   ..|.   |      |  . .. .. |.|| ...    ||  ...  . ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FTSSTVYKIALQTLDRLRVLHEAGWLNRDVKAQNFAVGLGEESSIVYMLDFGLTRKYLEHNGSRSLLRPHGPSVGTFPYAPLASLGFCDQSPIDDIEGWL
|.  .. ... |... |  .|. | . ||.| .|  .        .   |||| |..                .||  | .   |            |. 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL------------GYG

Y----------MIVHLLKGGLPWHNSKRALNLPKVREWKMYCRRPGGKHYLFAGIPKGWADIFDVIVNTAPHETPDYNKIANMVLSIARNELIDLTAPFD
.          ..  .| |  |..      .. .. .  .                                 .|.   . .  |    .. .     . 
KCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG---------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

----WQVNPVL
    .   | .
DEWDIKCHPWF

Kinase C09B9.4.AA TTBKL 207-293 21 6.8e-08 22.81 In-house 204-288 (288) Show / Hide
Range on Protein: 207-293
Range on HMM: 204-288/288
Sequence Identity: 21% (19 aa)

CDQSPIDDIEGWLYMIVHLLKGGLPWHNSK-RALNLPKVREWKMYCRRPGGKHYLF--AGIPKGWADIFDVIVNTAPHETPDYNKIANMV
..|.. ||.  |.|||. |..| |||.|.. .     .. . |. .       ...  ...|.  ....  . .  ....||| .| .  
KEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKM----EIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF