Gene C28A5.6 (Nematode worm)
C28A5.6
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| C28A5.6.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 235 | Kinase domain by global Sugen HMM | Fasta, JSON |
| C28A5.6.AA | Protein | Genbank | 1061 | None | Fasta, JSON |
Protein domains of C28A5.6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | C28A5.6.AA | S_TKc | 459-699 | 14 | 3e-07 | -70.52 | SMART | 16-231 (231) | Show / Hide |
Range on Protein: 459-699 Range on HMM: 16-231/231 Sequence Identity: 14% (39 aa) WLVQNIKSGCMCSAKLVSRKNPEHLQLQKNLDKERKILYDLLPELSNPSHIARLVDIGYDDDFKFLIFEDFGM---DLLTLFDEFGAV-----LNPTTMF ......|.| . | .. ... .|..|| . .| .| |. .| |. ....| . ||... .. | ... . YKCRHKKTGRIVAIKIIK----------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR LISYFTFNAIKELHSFDIVHLDIRPSSFSVNQHPFNIKITDY--SRCMTRNSCL--RIYLAPARLRTYIVPTCLLNTYFHSHLS-AY-------MLFLCT . | ...|.. .|| |.| |. |. ... .|||.| .| . ... . |.|| | .. . .|. . FYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--TTFCGTPWYMAPEVL---------------GYGKCKCDWWSCGCILYEML AEKLPWFGDAENMFKLKEVFFNDPLNYLYDGCADFVPLVACFIA-NKK--LTYETFME-----KMSKYL . . |. . . |||. .. .. . . .| .. |. .. CGYPPFP-QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | C28A5.6.AA | CK1 | 504-578 | 16 | 3e-06 | 17.79 | In-house | 84-163 (339) | Show / Hide |
Range on Protein: 504-578 Range on HMM: 84-163/339 Sequence Identity: 16% (13 aa) SNPSHIARLVDIGYDDD--FKFLIFEDFGMDLLTLFD--EF-GAVLNPTTMFLISYFTFNAIKELHSFDIVHLDIRPSSF ...... ...... .| ..... . .|..| |.. . . .. .| . | . . .|....|. ..| || |. | HCGCPHPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNF |
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| Kinase | C28A5.6.AA | Ciliate-C3 | 552-592 | 41 | 5.2e-05 | 14.32 | In-house | 101-140 (140) | Show / Hide |
Range on Protein: 552-592 Range on HMM: 101-140/140 Sequence Identity: 41% (17 aa) ISYFTFNAIKELHSFDIVHLDIRPSSFSVNQHPFNIKITDY || || || . ||| ||..| .| . .||| |. ISKQILQAIDYLHEHNIVHGDIKFSNILINSKD-EIKIIDF |
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| Kinase | C28A5.6.AA | Ciliate-B2 | 557-576 | 30 | 6.7e-05 | 7.35 | In-house | 114-133 (197) | Show / Hide |
Range on Protein: 557-576 Range on HMM: 114-133/197 Sequence Identity: 30% (6 aa) FNAIKELHSFDIVHLDIRPS ... .... .|.||||.|. IDGLIQFRMYNILHLDIKPQ |
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| Kinase | C28A5.6.AA | TKL-Unique | 563-591 | 37 | 7.5e-05 | 13.24 | In-house | 126-160 (290) | Show / Hide |
Range on Protein: 563-591 Range on HMM: 126-160/290 Sequence Identity: 37% (13 aa) LHSFD--IVHLDIRPSSFSVNQH----PFNIKITD ||. . | |.|...|.| |... ..|||| | LHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICD |
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| Kinase | C28A5.6.AA | Ciliate-E1 | 56-591 | 2 | 0.000269 | 10.43 | In-house | 74-152 (202) | Show / Hide |
Range on Protein: 56-591
Range on HMM: 74-152/202
Sequence Identity: 2% (15 aa)
IVIDEKEKALLKEIQ---KFELEVKKGTTNKYSSSSEFSSSNSDACDSDGETSDTDAVEAMFKNENDATDIAWKRLKIMRQCCCSGSDCFSDKDLDAVSA
|.... .. |....| .
IIFECCCCSLKDYLQNHNR---------------------------------------------------------------------------------
SSSSHLISEEDGEVGEKKESEQPTDMVEPSSAPTTEETETENEEEDDKEKTDKEKLDAEKEKALAEKRLEREQKLYKDLKSSSDDTSSSIDDKMNFDDEI
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EYLEEMLDNIEKQKDRKGSKDETEDTDATGDEEDSMFEEVKSASNKSGAEKSSAEQTSNAGVETSFSQSYSSTTDTSSAMLDSESIIITSSDPDADNADL
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DRNIEKFNWDSDDLYRSTDTDSEVENLLDYLSTAMNISDKVFSEFMVVGEETTPLLKEKLKTFQLPMPRFLKNTKYEMMEELDPDGPISEALGNNPESNS
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STSNQFWLVQNIKSGCMCSAKLVSRKNPEHLQLQKNLDKERKILYDLLPELSNPSHIARLVDIGYDDDFKFLIFEDFGMDLLTLFDEFGAVLNPTTMFLI
... .. . .. . . |
------------------------------------------------------------------------------LEYWQQCQQNQNQFTFQQKMQI
SYFTFNAIKELHSFDIVHLDIRPSSFSVNQHPFNIKITD
. . .. |||.. | |.|| |. .|. | ...|
IFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCD
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| Kinase | C28A5.6.AA | Worm2 | 556-580 | 60 | 0.000691 | 8.49 | In-house | 126-150 (242) | Show / Hide |
Range on Protein: 556-580 Range on HMM: 126-150/242 Sequence Identity: 60% (15 aa) TFNAIKELHSFDIVHLDIRPSSFSV || | .|| . ||||||||||. TFYCISDLHKICYHHLDIRPSSFSL |
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| Kinase | C28A5.6.AA | CDK-DD1 | 560-591 | 40 | 0.000727 | 7.14 | In-house | 111-141 (379) | Show / Hide |
Range on Protein: 560-591 Range on HMM: 111-141/379 Sequence Identity: 40% (13 aa) IKELHSFDIVHLDIRPSSFSVNQHPFNIKITD |.|.|. | |.|| |. .| . |||| INECHNQGIMHRDIKPANLLINNR-GDLKITD |
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| Kinase | C28A5.6.AA | CMGC | 502-576 | 15 | 0.00088 | 7.28 | In-house | 77-213 (513) | Show / Hide |
Range on Protein: 502-576 Range on HMM: 77-213/513 Sequence Identity: 15% (22 aa) ELS----------------NPSHIARLVDIGYDDDFK-----------------FLIFEDFGMDLLTLFDEFGA-----VLNPTTMFL------------ .|. .. .| .| || |... . .|.|| ..||. . .. .| . HLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHN ISYFT---------FNAIK--ELHSFD--IVHLDIRPS | ||. ....| .|| . |.| |. |. IKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPE |
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