C38C3.4

Species: Nematode worm
Alias: C38C3.4, CE30257, aSWK149
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: V:-18.84, WormBase Physical Map location: V: 1481871-1482413,

Classification

Group: CK1
Family: Worm6

Sequence

Name Sequence Type Origin Length Description Download
C38C3.4.AA Protein Genbank 307 None Fasta, JSON
C38C3.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 248 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of C38C3.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase C38C3.4.AA Worm6 36-283 37 9.20000000001e-129 434.07 In-house 1-261 (279) Show / Hide
Range on Protein: 36-283
Range on HMM: 1-261/279
Sequence Identity: 37% (99 aa)

YAVGKKVAQGRYGAVYEVLRRSDGK--PFACKLEI--CEAHSHGLDQDYSVMTKAAKRGAENLVRMIDRGKIEEH-FKFIIMPLLGENLMNLRFLFEDGR
. |.||...|..||||.|...||.|  .||.|.|   ...... |.....|................||||.... |..|.|.|.|.||..||. ..|..
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICR--SFKDKSGELKTPR-TDIKFRGTNRYASLAAHYGDEQS
||..|||..|.. ...|. ||. |..|||.|..|||| ..|| ... |  .....|.|.||   ...| .||.||| |...||||.|||.||.|.|.||.
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQM-KEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQC

AKDDMESWFYMMIELISGNLPWSFMHRDQHKEVEFHR----IQAYLMGLKYQNTV--DYTFI
.|||.|||||||.|.|.|.||| .|....|.|.....    ..|..| . ....   ....|
RKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDI

Kinase C38C3.4.AA CK1 36-283 25 9.3e-90 304.5 In-house 1-339 (339) Show / Hide
Range on Protein: 36-283
Range on HMM: 1-339/339
Sequence Identity: 25% (86 aa)

YAVGKKVAQGRYG-AVYEV-----LRRSDG-----KPFACKLEIC-EAHSHGLDQDYSVMTKAAKRG-------------------AENLVRMIDRGKIE
. |.|| ..| .| ..|.|      . ...     . .|.|.|   ....| . .. ..| |. ..|                       ..... |. .
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

EHFKFIIMPLLGENLMNLRF--LFEDGRFSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQML------HQ-NPEALKLCLIDYGICR-SFK
.......|.|||.||. ||    . ...||..|.|..|.  .. .. .|  |..|||||..|||.   ...      |. |.|. .. .||.|..|  ..
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

DKSG------------ELKTPRT---DIKFRG-TNRYASLAAHYGDEQSAKDDMESWFYMMIELISGN--LPWSFMHR----------DQHKE---V---
||.|            ....||.     .||| | ||.|...| | ||. .||..|||||.||.. |.  |||. | .          ....|       
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

-----------------EFHRIQAYLMGLKYQNTVDYTFI
                 ||  |  |...|||. . || .|
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI

Kinase C38C3.4.AA TTBKL 36-250 28 8.3e-51 169.79 In-house 1-229 (288) Show / Hide
Range on Protein: 36-250
Range on HMM: 1-229/288
Sequence Identity: 28% (69 aa)

YAVGKKVAQGRYGAVYEVLRRSD-GKPFACKLEICEAHSHGLDQDY--S--------VMTKAAKRGAENLVRMIDRGKIEEHFKFIIMPLLGENLMNLRF
. . |....| .|.||.|  ..| .. .|.| |        ... .  .        |..| ...|.    .... ||..  . |..| |.|.||. || 
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEE--------KNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKD-YNFMVMTLCGPNLQDLRK

LFEDGR-FSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQ--NPEALKLCLIDYGICRSFKDKSGEL-----------KTPRT---DI
    .. || .| .|..   .  .. .|  |..|||.| .|.|.     .|.  ....  . |||.|..| ...|.||.           ..||.     
MMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWG----YHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKA

KFRGTNRYASLAAHYGDEQSAKDDMESWFYMMIELISGNLPWS
 |||| ||.|...| . ||. .||. ||.||.|||  | |||.
PFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWT

Kinase C38C3.4.AA TTBK 105-249 42 4.2e-38 132.27 In-house 68-207 (257) Show / Hide
Range on Protein: 105-249
Range on HMM: 68-207/257
Sequence Identity: 42% (62 aa)

EHFKFIIMPLLGENLMNLRFLFEDGRFSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQNPEALKLC-LIDYGICRSFKDKSGELKTP
..| ...| |.|.|| .||    .| ||||| ||| .  .| |.| |..|. ||||| ||| .       .||.  . | ..|.|  | .   .||  .|
DKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMG------RNPSTCRKCYMLDFGLARQYTNACGEVRPP

RTDIKFRGTNRYASLAAHYGDEQSAKDDMESWFYMMIELISGNLPW
|    |||| ||||  ||   |   .||. | |||..| . | |||
REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPW

Kinase C38C3.4.AA CK1-Unique 36-283 25 1.7e-32 109.99 In-house 1-263 (337) Show / Hide
Range on Protein: 36-283
Range on HMM: 1-263/337
Sequence Identity: 25% (70 aa)

YAVGKKVAQGRYGAVYEVLRRSDG------KPFACKLEICEAHSH--GLDQDYSVMTKAAKRG-----AENLVRMIDRGKIEEHFKFIIMPLLGENLMNL
. | |.   | || |..|    .|      . .. | |   .  |   |    .||    |        . .   .| .      ..|.| ..| ..  .
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFH-QHRDWWWIVMTMHGPSMEEC

RFLFEDGRFSLS------TGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICRS--FKDKSGELKTPRTDIKFRGTNR
...     | |.      . .....     |   |. |. ||..|  |.|  .|   ||      .  .||||||.  | ....... ||  ..|||. .
CMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQH----CYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKD

YASLAAHYGDEQSAKDDMESWFYMMIELISGN--LPWSFMHRDQHKEVEFHRIQAYLMGLKYQNTVDYTFI
|.. . |   |....|||||||||.. |. .   | |     |.        |  || |||.   |||  |
YCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWKL---DKIIPSGIDNIIVYLRGLKFEDPVDYRQI

Kinase C38C3.4.AA Dual 75-249 27 1.4e-30 100.01 In-house 46-225 (282) Show / Hide
Range on Protein: 75-249
Range on HMM: 46-225/282
Sequence Identity: 27% (52 aa)

GLDQDYSVMTKAAK-------RGAENLVRMIDRGKIEE-HFKFIIMPLLGENLMNLRFLFEDGRFSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFC
.|.    || |.|         | .. . ..|.||.|. . |...| . |  |   |  .  | .| ..    |.  .. || ||..||.||.|| .|| 
RLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFH

IADPQMLHQNPEALKLCLIDYGICRSFKD-KSGELKTPRTDIKFRGTNRYASLAAHYGDEQSAKDDMESWFYMMIELI-SGN-LPW
.        . .  .. . |..| |.. | . .. .|.|. .|. |. |||. |     .|  |||.|.| ||   |.  .. ..|
CG------LGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHGMSW

Kinase C38C3.4.AA CK1-A 36-249 34 1.1e-29 101.96 In-house 1-205 (261) Show / Hide
Range on Protein: 36-249
Range on HMM: 1-205/261
Sequence Identity: 34% (75 aa)

YAVGKKVAQGRYGAVYEVLRRSDGKPFACKLEICEAHSHGLDQDYSVMTKAAKRGAENLVRMIDRGKIEEHFKFIIMPLLGENLMNLRFLFEDGRFSLST
| . .|.  | .| .|  .   .|.  | |.|  .|.   |  .  | .  .  |.  . .|   |. |  .  ..| |||  | .| | | . ||.. |
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQ--GCVGIPHMRWYGC-EKDYNVMVMDLLGPSLEDL-FNFCKRRFTMKT

GLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICRSFKDKSGELKTP-RTDIKFRGTNRYASLAAHYGDEQSAKDDMES
 | ||   |  |  .|. ...|||||  || .      | |    || |||.|. . ..|.  .   | |.| .  || ||||. || | ||| .|||||
VLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMG--IGRHCN----KLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMES

WFYMMIELISGNLPW
  |.|.    | |||
MGYVMMYFNRGKLPW

Kinase C38C3.4.AA CK1-D 36-249 30 7e-24 81.03 In-house 1-205 (261) Show / Hide
Range on Protein: 36-249
Range on HMM: 1-205/261
Sequence Identity: 30% (66 aa)

YAVGKKVAQGRYGAVYEVLRRSDGKPFACKLEICEAHSHGLDQDYSVMTKAAKRGAENLVRMIDRGKIEEHFKFIIMPLLGENLMNLRFLFEDGRFSLST
| .|.|.  | .| .|     . .   | |||   ..   |. . | . |  . |    . .|     |  .  ..| |||  |  | | . . .||| |
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIE-SKFYKMMQGGIG--IPEIRWCGQEGDYNVMVMDLLGPSLEDL-FNYCHRKFSLKT

GLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICRSFKDKSGELKTP-RTDIKFRGTNRYASLAAHYGDEQSAKDDMES
 | ||.  |. |. .|   ..|||||  || .   .  .         .||.|. . ..|   .   | | .    || ||||.  | | ||| .||.||
VLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNM------VYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLES

WFYMMIELISGNLPW
  |...    | |||
LGYVLMYFNRGSLPW

Kinase C38C3.4.AA CK1-Unclassified 36-249 32 1.6e-23 66.34 In-house 1-216 (244) Show / Hide
Range on Protein: 36-249
Range on HMM: 1-216/244
Sequence Identity: 32% (73 aa)

YAVGKKVAQGRYGAVYEVLRRSDGKPFACKLEICEAHSHGLDQDYSVMTKAAKRGA------ENLVRMIDRGKIEE-HFKFIIMPLLGENLMNLRFLFED
| |..|. ||  | .|..    ... .|.|||   . .  |.    .| .. ..|.       .. .|.  |. |. .. ...| |||..|  | | .  
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIM-QYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDL-FNMCN

GRFSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIA-DPQMLHQNPEALKLCLIDYGICRSFK--DKSGELKTPRTDIKFRGTNRYASLAAHYGDE
..||| | | .|   || |. ||  ...|||||  ||..    .. ||      . .||.|.   ..  || |.  . | . .. || ||||. ||.| |
RKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQ------VYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIE

QSAKDDMESWFYMMIELISGNLPW
|| .||.||  | .| .. | |||
QSRRDDLESLGYVLIYFLKGSLPW

Kinase C38C3.4.AA CK1 36-249 31 1.1e-22 75.11 In-house 1-216 (271) Show / Hide
Range on Protein: 36-249
Range on HMM: 1-216/271
Sequence Identity: 31% (69 aa)

YAVGKKVAQGRYGAVYEVLRRSDGKP--FACKLEICEAHSHGLDQDYSVMTKAAK---RG-AENLVRMIDRGKIEE-HFKFIIMPLLGENLMNLRFLFED
| ||.|. ||  | .|.. . ..|.    |.|||   .    |.  . ...   .    . .... .|.  |. |. .. ...| |||..|  | | | .
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDL-FNFCN

GRFSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICRSFKD-KSGELKTPRTDIKFRGTNRYASLAAHYGDEQS
..||| | | .|   || |. .|  ...|||||  ||..       .. .. .. .||.|.   ..| |...    |.. .. || ||||. .|.| |||
RKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-----YGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQS

AKDDMESWFYMMIELISGNLPW
 .|||||  |... .. | |||
RRDDMESLGYVLMYFLRGSLPW

Kinase C38C3.4.AA S_TKc 36-305 12 9.9e-11 -19.55 SMART 1-231 (231) Show / Hide
Range on Protein: 36-305
Range on HMM: 1-231/231
Sequence Identity: 12% (37 aa)

YAVGKKVAQGRYGAVYEVLRRSDGKPFACKLEICEAHSHGLDQDYSVMTKAAKRGAENLVRMIDRGKIEEHFKFIIMPLLGENLMNLRFLFEDGR-----
| ...|. .| .| || .  ...|. .|.|          . .  ... |    . .|.|...|      .. ...| ... .| .|. . .. .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FSLSTGLRLALFAIQPIQSLHQLGYVHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICRSFKDKSGELKTPRTDIKFRGTNRYASLAAHYGDEQSA
  |.  .  ...   .. .. .|..| .|||.| .|  . .            . ..| |..| .               | ||  | .           
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------HIKICDFGLARQL-------------TTFCGTPWYMAPEVL-------

KDDMESWFY----------MMIELISGNLPWSFMHRDQHKEVEFHRIQAYLMGLKYQNTVDYTFISEMVQLAMRNN-----GVRMNEK-------FDWQ
     .. .          ...|...|  |..      . .. |..|             .  ... ...  .. .     ..    .         | 
-----GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase C38C3.4.AA Pkinase 36-65 36 1.1e-05 21.14 Pfam 1-30 (293) Show / Hide
Range on Protein: 36-65
Range on HMM: 1-30/293
Sequence Identity: 36% (11 aa)

YAVGKKVAQGRYGAVYEVLRRSDGKPFACK
| .|.|. .| .| ||.  ....|| .|.|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVK

Kinase C38C3.4.AA Pkinase 150-250 19 0.006953 11.28 Pfam 124-213 (293) Show / Hide
Range on Protein: 150-250
Range on HMM: 124-213/293
Sequence Identity: 19% (20 aa)

LHQLGYVHRDIKASNFCIADPQMLHQNPEALKLCLIDYGICRSF-KDKSGELKTPRTDIKFRGTNRYASLAAHYGDEQSAKDDMESWFYMMIELISGNLP
.|. | .|||.| .|. | .   .       .....| |... |   ... ..|.   . ..            | . . | || |   ...|...|..|
CHSMGIIHRDLKPENILIDNNGHIDA-----CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQYYGPKVDMWSCGCILYEMLCGRPP

WS
..
FP