Gene F38E1.3 (Nematode worm)

F38E1.3

Species: Nematode worm
Alias: CE04522, aSWK136, F38E1.3
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 8378738-8380487, WormBase Genetic Map location: V:1.41,

Classification

Group: CK1
Family: Worm6

Sequence

Name Sequence Type Origin Length Description Download
F38E1.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 266 Kinase domain by global Sugen HMM Fasta, JSON
F38E1.3.AA Protein Genbank 310 None Fasta, JSON

Protein domain

Protein domains of F38E1.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F38E1.3.AA Worm6 25-288 47 1.6e-149 503.01 In-house 1-279 (279) Show / Hide 
Range on Protein: 25-288
Range on HMM: 1-279/279
Sequence Identity: 47% (133 aa)

YVIDKLLGEGGFGAVYKVKDSKTGN--FYAMKVEKKQEK-KPSKLKMEIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELAGSSLADLKRNR-GK
. ..|..|||||||||||.|.....  ..|||.||..|. | ..||||.|.||.|.... . ||.||.||||.|..||...||.| | .|.||..|| ..
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHK-CRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDR

AFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGA-----DDKQHTIYILDFGISR--RIINNQNKLKTPR-VTIRFKGTLKFASLSCHKGIEMG
.|...|||....|||||.||||..||||||.||.||..|      |...||||.||||..|  . .|..|.|.|||  .. |.||...|.|.||||.|..
KFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQC

WKDDCESWFYMLLDLIVPFGLVWRGANDKDTVCKLKEEARGKK-----EMFQGIKCGVELNKIIVYIDKLQYQDHVDYQYI
.||||||||||....||. .| ||. .|.| |.|.|...| ..     .|| |. . .|.|.|  |||...|.|..||..|
RKDDCESWFYMMVEMIVG-CLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase F38E1.3.AA CK1 25-288 28 3.2e-103 349.21 In-house 1-339 (339) Show / Hide 
Range on Protein: 25-288
Range on HMM: 1-339/339
Sequence Identity: 28% (97 aa)

YVIDKLLGEGGFG-AVYKV-----KDSKTG-----NFYAMKVEKKQEK--KPSKLKMEIMILKLVCN---------------ERQTSHFTKIIDRGKKDK
. . |..|||||| ..|||     ||.|..      .||||||.|...  .|.......|..|| ..               . . ... .... .....
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

EGFFFLVMELAGSSLADLKR---NRGKAFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGA-------------DDKQHTIYILDFGISR-RII
... ..||.| | .| ||..   . .. |. .|.| . .|.|||.|..| .||||||.||.||..|.             ... ...|..|||..| . .
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

NNQN------------KLKTPRV---TIRFKG-TLKFASLSCHKGIEMGWKDDCESWFYMLLDLIVPF-GLVWRGANDKDT-----VCKLKEEARGKKEM
....            ....||    .  | | |....|..||.|.|.| .||..||||||......  || |.. .|..      | | |.| . .|.|
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

FQGIK---------CGVELNKIIVYIDKLQYQDHVDYQYI
 . ..         |  |. ||. ||..|.|.|  ||..|
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase F38E1.3.AA TTBKL 25-292 31 2.1e-72 243.72 In-house 1-288 (288) Show / Hide 
Range on Protein: 25-292
Range on HMM: 1-288/288
Sequence Identity: 31% (92 aa)

YVIDKLLGEGGFGAVYKVKDSKT-GNFYAMKVEKKQ-EKKPSKLKMEIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELAGSSLADLK--RNRGK
..| |..||||||.||.|.|.|. . ..|||.||.. |...|..|||. .|..  ...  .|| |... ||...  . |.||.| | .| ||.   ...|
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKL-QPNGSPHFPKCHCSGKRKD--YNFMVMTLCGPNLQDLRKMMPNKK

AFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADDK----QHTIYILDFGISRRIINNQN-----------KLKTPRV---TIRFKGTLKFAS
.|.  | . .. |||.|  ..| .||||||.||.|.. |. |.    ....|..|||..|.......           ....||    .  | ||....|
RFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCS

LSCHKGIEMGWKDDCESWFYMLLDLIVPFGLVWRGANDKDTVCKLKEEARGKKEMFQG---IKCGVELNKIIVYIDKLQYQDHVDYQYIYKTL
.  | . | | .||  ||.||.  | ..  | |.. .||. . ..|..  ... .       .|  |. |.  ..  |.|.|  ||..||. .
PNMHDRKEQGRHDDLWSWMYMIIELHCG--LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase F38E1.3.AA Dual 26-292 29 1.1e-52 175.51 In-house 3-282 (282) Show / Hide 
Range on Protein: 26-292
Range on HMM: 3-282/282
Sequence Identity: 29% (83 aa)

VIDKLLGEGGFGAVYKVKDSKT----GNFYAMKVEKKQEKKPS-KLKMEIMILKLVCNERQTSH------FTKIIDRGKKDKEGFFFLVMELAGSSLADL
|. .||| |||. ||.| ...        |..|.|   ..|    || |  . ...   |. .       |   .|.||  .    ..|| . |.|| . 
VV-NLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQEI

KR-NRGKAFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADDKQHTIYILDFGISRRIIN-NQNKLKTPRVTIRFKGTLKFASLSCHKGIEMG
 |    .... ..   |  | |.|  |||  |..||. |||||.|| ...  |.| .||.| |  |     | .|.| .. . |.. .|.  | .  . |
RRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQG

WKDDCESWFYMLLDLIVPFG-LVWRGANDKDTVCKLKEEARGKKEMFQGIKCGVELNKIIVYIDKLQYQDHVDYQYIYKTL
 ||| |.| ||. ||. |   . ||  .|   . | |..    .  .|  .   .| ....|.. .||.   || |.   |
RKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase F38E1.3.AA CK1-Unique 25-236 30 3.2e-49 168.77 In-house 1-233 (337) Show / Hide 
Range on Protein: 25-236
Range on HMM: 1-233/337
Sequence Identity: 30% (72 aa)

YVIDKLLGEGGFGAVYKVKDSKTG------NFYAMKVEKKQEKKP-SKLKMEIMILKLVCNER----QTSHFTKIIDRGKKDKEGFFFLVMELAGSSLAD
. . |..| ||.| |..| ....|        |.|| | .  .|. . |. |  ..|  |       .  || ...| .  .     ..|| . | |.  
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRD--WWWIVMTMHGPSMEE

LKRNRGK-AFTCP------TGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADD--KQHTIYILDFGISRR--IINNQNKLKTPRVTIRFKGTLKFAS
...  .  .||        . .  . |||.. |  |.|||.||..||.|.  .|    .||..|.||.||.||  .. | . .. || .. | |......
CCMMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCP

LSCHKGIEMGWKDDCESWFYMLLDLIVP-FGLVWR
 |||.  | | .|| |||||||..|.    || |.
CSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWK
Kinase F38E1.3.AA TTBK 25-288 36 2e-47 163.86 In-house 1-257 (257) Show / Hide 
Range on Protein: 25-288
Range on HMM: 1-257/257
Sequence Identity: 36% (98 aa)

YVIDKLLGEGGFGAVYKVKDSKTG-NFYAMKVEKKQEKKPSKLKMEIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELAGSSLADLKRNRGK-AF
  . |  | |||| .|  ||  .     |.|||. | .|   ||||. .||         |  . |  |  ||  | ..||.| | .|||| |.  . .|
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPK-QVLKMEVAVLKKL---QGCDHVCRFIGCGRNDK--FNYMVMQLQGKNLADLRRKQPRGCF

TCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACG-ADDKQHTIYILDFGISRRIINNQNKLKTPRVTIRFKGTLKFASLSCHKGIEMGWKDDCESWF
.  | | .  | |.. |  |  || ||| || ||| | .  .   .|.||||  |. .| .    .||    | ||  .||   |.  ||| .||  | |
SLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLF

YMLLDLIVPFGLVWRGANDKDTVCKLKEEARGKKEMFQGIKCGVELNKIIVYIDKLQYQDHVDYQYI
|||   ..   | ||   ||| | ..||..   . . .   |  |.   .  |  |.|.|  ||| |
YMLVEFVQGQ-LPWRKIKDKDQVGEMKEKYD-HRMLLK--HCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase F38E1.3.AA CK1-Unclassified 25-177 33 1.5e-39 114.38 In-house 1-157 (244) Show / Hide 
Range on Protein: 25-177
Range on HMM: 1-157/244
Sequence Identity: 33% (53 aa)

YVIDKLLGEGGFGAVYKVKDSKTGNFYAMKVEKKQEKKPSKLKMEIMILKLVCNER-----QTSHFTKIIDRGKKDKEGFFFLVMELAGSSLADLKRNRG
| . . .| | || .||.....|. ..|.|.|||  |  . |. |. |.. . |.         ...|..  |. ..... ..||.| |.|| ||.   .
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFI-KGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCN

KAFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACG-ADDKQHTIYILDFGISRR
. |.  | |    | ..  | ||...|||||.|| ||  |    ..|..|| |||.| |
RKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKR
Kinase F38E1.3.AA CK1 25-177 31 2.8e-33 112.03 In-house 1-158 (271) Show / Hide 
Range on Protein: 25-177
Range on HMM: 1-158/271
Sequence Identity: 31% (50 aa)

YVIDKLLGEGGFGAVYKVKDSKTGNF--YAMKVEKKQEKKPSKLKMEIMILKLVCN---ERQTSHFTKIIDRGKKDKEGFFFLVMELAGSSLADLKRNRG
| . . .|.| || .|.... ..|..  .|.|.||.  | |  |. |. |.|   .   . |  .. ...  |. ... . ..||.| | || ||.   .
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHP-QLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCN

KAFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGA-DDKQHTIYILDFGISRR
. |.  | | .  | ..  | .|...|||||.|| ||  |    ..|..|| |||.. |
RKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKR
Kinase F38E1.3.AA CK1-A 25-288 27 1.5e-25 87.11 In-house 1-261 (261) Show / Hide 
Range on Protein: 25-288
Range on HMM: 1-261/261
Sequence Identity: 27% (73 aa)

YVIDKLLGEGGFGAVYKVKDSKTGNFYAMKVEKKQEKKPSKLKMEIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELAGSSLADLKRNRGKAFTC
| . . .| | || .|     . |.  |.|.|... . | .|  |  . ...   .    . ..   |.     .  .||.| | || ||     . || 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHP-QLIYEAKVYRIL---QGCVGIPHMRWYGCEKD--YNVMVMDLLGPSLEDLFNFCKRRFTM

PTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADDKQHTIYILDFGISRRIINNQNKLKTP-RVTIRFKGTLKFASLSCHKGIEMGWKDDCESWFYM
 | | .  | .   | .|...|||||.|| ||  | .     ....|||....   .. .   | |      || ..||.  | |||   .|| ||  |.
KTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYV

LLDLIVPFGLVWRGANDKDTVCKLKEEARGKKEMFQGIK-----CGVELNKIIVYIDKLQYQDHVDYQYI
..       | | |   |    | | |    | |   |.        |.  .. |. .|..... || |.
MMYFNRGK-LPWQGM--KAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase F38E1.3.AA CK1-D 25-288 29 1.4e-24 83.56 In-house 1-261 (261) Show / Hide 
Range on Protein: 25-288
Range on HMM: 1-261/261
Sequence Identity: 29% (79 aa)

YVIDKLLGEGGFGAVYKVKDSKTGNFYAMKVEKKQEKKPSKLKMEIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELAGSSLADLKRNRGKAFTC
| | . .| | || .|  .. .|.   |.|.|  . | | .|..|  . |..       .   .   |      .  .||.| | || ||    .. |  
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHP-QLHIESKFYKMMQGGIGIPEIRWCGQEGD-----YNVMVMDLLGPSLEDLFNYCHRKFSL

PTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADDKQHTIYILDFGISRRIINNQNKLKTP-RVTIRFKGTLKFASLSCHKGIEMGWKDDCESWFYM
 | | ...| .   | .| . |||||.|| ||  |   . ...||.|||...|    . .   | |      || ..||.  |.|||   .|| ||  |.
KTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYV

LLDLIVPFGLVWRGANDKDTVCKLKEEARGKKEMFQGIKC-----GVELNKIIVYIDKLQYQDHVDYQYI
|.       | | |   | .  . | |    | |   |.        |  . . |  .|...|. || |.
LM-YFNRGSLPWQGL--KAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase F38E1.3.AA Pkinase 25-194 27 2.9e-24 86.88 Pfam 1-177 (293) Show / Hide 
Range on Protein: 25-194
Range on HMM: 1-177/293
Sequence Identity: 27% (51 aa)

YVIDKLLGEGGFGAVYKVKDSKTGNFYAMKVEKKQEKKPSKLKM-----EIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELA--G-SSLADLK-
|.| . .|.|.|| ||| .. .||  .|.|. ||...|..|..      || |.| ..      .  ...|      ..   .|||..  | . ..||. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFD

---RNRGKAF--TCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADDKQHT---IYILDFGISRRI-INNQNKLKTPRVTIRF
   . |...|  .  .  ..  | |.. | .|..|.|||||||.|. .   .. |.   . | |||... . . |.  ..|. .|...
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWY
Kinase F38E1.3.AA S_TKc 25-308 21 2.5e-15 47.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-308
Range on HMM: 1-231/231
Sequence Identity: 21% (67 aa)

YVIDKLLGEGGFGAVYKVKDSKTGNFYAMKVEKKQEKKPSKLKMEIMILKLVCNERQTSHFTKIIDRGKKDKEGFFFLVMELAGS---SLADLKRNRGKA
| | ...|.|.|| |||... |||  .|.|. |       ... || |||      .  .  |..|       .....|||...    .| |. ..||. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----FTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADDKQHTIYILDFGISRRIINNQNKLKTPRVTIRFKGTLKFASLSCHKGIEMGWKD-
     |.  .  .. .| ..| | .|.||.|||||||.|  .       .| | |||..|..               | ||. . .         |.   
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL-----GYGKC

DCESW-----FYMLLDLIVPFGLVWRGANDKDTVCKLKEEARGKKEMFQGIKCGVELNKIIVYIDKLQYQDHVDYQYIYKTLV-DACD--TCGGNMD---
 |  |     .| .|    ||       ... .  |..                                ..   . | | |. |  .  |.   .    
KCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

----APYD
     |. 
DIKCHPWF
Kinase F38E1.3.AA TyrKc 25-228 18 6.1e-05 -142.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-228
Range on HMM: 1-280/280
Sequence Identity: 18% (53 aa)

YVIDKLLGEGGFGAVYKVKDSKTGNFYAMKVEKKQEKKPSKLKMEIMILKLV--CNERQTSHFTKIIDRGKKDKEGF-----FFLVMELA--GSSLADLK
 . .| |||| || ||| . .      | |. |.       .  |. |.. .   ..     .  ... | .    |      ..|||..  |. .  |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLKDYLR

RNRGKAFTCPTGLSVSQQCLEACEDLHKHGFIHRDLKPANFACGADDKQHTIYILDFGISRRIINN-------QNKLK----TPR--VTIR---------
..|.| .. .. || . |  . .| ||....|||||   |   |..    |. | ||| || | .        . . |      .  . ||         
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

--------------------------FKG--------------TLKFASLSCHKG----------------IEMGWKDDCES--WFYMLLDLI
                            |                .   . . .                 ... |. | |.   |  . ...
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF