Gene F41G3.5 (Nematode worm)
F41G3.5
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| F41G3.5.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 235 | Kinase domain by global Sugen HMM | Fasta, JSON |
| F41G3.5.AA | Protein | Genbank | 263 | None | Fasta, JSON |
Protein domains of F41G3.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | F41G3.5.AA | Worm6 | 1-219 | 48 | 3.5e-121 | 408.88 | In-house | 47-279 (279) | Show / Hide |
Range on Protein: 1-219 Range on HMM: 47-279/279 Sequence Identity: 48% (113 aa) MEAVVLRSLLPIRSPYFCRVFFCGKAEK--FNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCINL------D ||..|| . .....||... .|| .. ||...||||||||..||.|.|.|||| .|||.|.||...||..||..||||||.||.||||. . MECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDN NPHQLVMVDFGMCR-KYLNDGGTQLRHPRWSVHGFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTMEEHIHVE-HSKQVARTTG--LR . |.. |.|||||| |.... |..||.||| ..|||||||||||| |.|.. |||.|.|. ||..||..||.|||. |..| ||| | |. |.| .. EHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMM EFLSG-CPK-QLVHILLYIDNLRFYDAPDYALI ... | ||| ....|. |||.....|.|||. | RMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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| Kinase | F41G3.5.AA | CK1 | 1-219 | 31 | 4.2e-94 | 318.95 | In-house | 56-339 (339) | Show / Hide |
Range on Protein: 1-219 Range on HMM: 56-339/339 Sequence Identity: 31% (90 aa) MEAVVLRSLL------------------PIRSPYFCRVFFCGKAEK-FNFLIMTLVGKNLSELRA-NCP-NRKFSRRTGLQIGIQMINAIQQLHSIGFIH .|..... | . ..|..|.. ..|. .. .|...|||.|.||..||. |.. ||||| .|.|.|.|||..|....|..|||| EEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIH RDIKPANFCINL--------------DNPHQLVMVDFGMCR-KYLNDGGTQ----------LRHPRWS---VHGFRG-TVRYAPLATHYGRDSCRKEDLE |||||.|||. . .. .|..|.||||.| ||....|.. . |. . .|||| |.||.....| |.. .|. ||. RDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLW TIFYVLVELLVGT--LPWMTME------EHIHVEHSKQVARTTGLREFLS---------GCPKQLVHILLYIDNLRFYDAPDYALI . ||.|.|.|.|| |||. |. .| ||. |. ... . ... .||... |. ||..|..||.|||. | SWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQ-VEKMKYEFIDEKKMSTPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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| Kinase | F41G3.5.AA | TTBKL | 1-223 | 35 | 2.5e-66 | 222.95 | In-house | 46-288 (288) | Show / Hide |
Range on Protein: 1-223 Range on HMM: 46-288/288 Sequence Identity: 35% (87 aa) MEAVVLRSLLPIRSPYFCRVFFCGKAEKFNFLIMTLVGKNLSELRANCPNRK-FSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCINLD-----NP ||. || | | ||.|... ..|| ...||..|||.|.||. ||. ||.| ||..| . |||| . |..|.|..||||||.||.|.|. . . MEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERC HQLVMVDFGMCRKYLNDGGTQ----------LRHPRW--SVHGFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTMEEHIHVEHSKQVA . . .||||.|.|... | . .| || ..||||.||. .. | ... |. || .|...||..| ||| ||.. .|| |. RHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNM RTTGLREFL---SGCPKQLVHILLYIDNLRFYDAPDYALIRGLL .. | . .||... . .. .||.|| ||| |. .. KDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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| Kinase | F41G3.5.AA | TTBK | 1-219 | 40 | 7.4e-62 | 211.81 | In-house | 44-257 (257) | Show / Hide |
Range on Protein: 1-219 Range on HMM: 44-257/257 Sequence Identity: 40% (90 aa) MEAVVLRSLLPIRSPYFCRVFFCGKAEKFNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCI--NLDNPHQLV || ||. | .. || . || .|||...|.| ||||..|| . | .|| | |..|.|....|.. ||.|| |||||| || . | . . MEVAVLKKL--QGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCY MVDFGMCRKYLNDGGTQLRHPRWSVHGFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTMEEHIHVEHSKQVARTTGLREFLSGCPKQL |.|||. |.|.| | . | || .| ||||||||| | |. |. || .||.||| ..| ||| . | . |. . . | | ||... MLDFGLARQYTNACG-EVRPPR-EVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDH---RMLLKHCPHEF VHILLYIDNLRFYDAPDYALI . | | . | |||.|| HQFMDHIKSLNYEDRPDYQLI |
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| Kinase | F41G3.5.AA | Dual | 28-223 | 30 | 9.6e-36 | 117.59 | In-house | 85-282 (282) | Show / Hide |
Range on Protein: 28-223 Range on HMM: 85-282/282 Sequence Identity: 30% (60 aa) KFNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCINLDNP-HQLVMVDFGMCRKYLNDGGTQLRHPRWSVHGF | ....| ..| | | | . .| . ..|||. ||| |||||..||.|||||| . |. . | ||.. |||. . | .| | . KCKYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVK-M RGTVRYAPLATHYGRDSCRKEDLETIFYVLVELL-VGT-LPWMTMEEHIHVEHSKQVARTTGLREFLSGCPKQLVHILLYIDNLRFYDAPDYALIRGLL |. ||| | .| || |||. | . |. . ..| . . .|. .. . . | |..|. .. |.... . .|||. .| | YGCGRYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL |
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| Kinase | F41G3.5.AA | CK1-D | 19-219 | 33 | 7.9e-34 | 116.67 | In-house | 59-261 (261) | Show / Hide |
Range on Protein: 19-219 Range on HMM: 59-261/261 Sequence Identity: 33% (69 aa) RVFFCGKAEKFNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCINLDNPHQLV-MVDFGMCRKYLNDGGTQLR .. .||. .| ..| |.| | .| | .|||| .| | .. ||| |. .|. |||||||| || . | ..| ..|||. ..| | |. EIRWCGQEGDYNVMVMDLLGPSLEDLFNYC-HRKFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRY-RDARTHQH HPRWSVHGFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTMEEHIHVEHSKQVAR---TTGLREFLSGCPKQLVHILLYIDNLRFYDAP | || ||| . || | . |..||| . |||. |.||| . . ... | . . .| |.. .. . | ||.| | | IPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKP DYALI ||. . DYCYL |
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| Kinase | F41G3.5.AA | CK1 | 14-167 | 35 | 1.1e-32 | 109.92 | In-house | 62-217 (271) | Show / Hide |
Range on Protein: 14-167
Range on HMM: 62-217/271
Sequence Identity: 35% (58 aa)
SPYFCRVFFCGKA--EKFNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCINL--DNPHQLVMVDFGMCRKYL
.... .. ||. ...|...|.| |..| .| | ||||| .| | |. ||| |. .|. .|||||||| ||.. . . ||. ..|||. .|.
CHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFC-NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYR
NDGGTQLRHPRWSVH-------GFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWM
.. | .. ||.||| . ||.|. |. |.| . |||. .| |.|||.
--------DDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQ
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| Kinase | F41G3.5.AA | CK1-A | 13-219 | 30 | 1e-31 | 109.29 | In-house | 53-261 (261) | Show / Hide |
Range on Protein: 13-219 Range on HMM: 53-261/261 Sequence Identity: 30% (65 aa) RSPYFCRVFFCGKAEKFNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCINLD-NPHQLVMVDFGMCRKYLND . . . .. . |. .| ..| |.| | .| | .|.|. .| | . ||| | .| .|||||||| || . .. .| ..|||. .|| | GCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFC-KRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKY-RD GGTQLRHPRWSVHGFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPW---MTMEEHIHVEHSKQVARTTGLREFLSGCPKQLVHILLYIDNL |. | . ||.||| . | | . |..|.| . ||.. |.||| | . | .| . . | | .. .. |. || SRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNL RFYDAPDYALI || ..||| . RFEEQPDYMYL |
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| Kinase | F41G3.5.AA | CK1-G | 19-219 | 31 | 1.2e-26 | 87.26 | In-house | 60-266 (266) | Show / Hide |
Range on Protein: 19-219 Range on HMM: 60-266/266 Sequence Identity: 31% (66 aa) RVFFCGKAEKFNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCI---NLDNPHQLVMVDFGMCRKYLNDGGTQ .|.. | |.| ..| | | | | | .|||| .| ... ||||. ....|| | ||.|| || | ..| . ..|||| ..| | |. QVYYFGQCGKYNIMVMDLLGPSLEDLFDWC-DRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYI-DPETK LRHPRWSVHGFRGTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWMTMEEHIHVEHSKQVA---RTTGLREFLSG--CPKQLVHILLYIDNLRF | || || || || | |.| . . | | ||| . | . . | | . . |.|. | |. .| | QHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDF YDAPDYALI . ||| . FECPDYDYL |
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| Kinase | F41G3.5.AA | CK1-Unclassified | 16-112 | 40 | 2.5e-26 | 74.73 | In-house | 63-165 (244) | Show / Hide |
Range on Protein: 16-112 Range on HMM: 63-165/244 Sequence Identity: 40% (42 aa) YFCRVFFCGKAEK--FNFLIMTLVGKNLSELRANCPNRKFSRRTGLQIGIQMINAIQQLHSIGFIHRDIKPANFCIN-LDNPHQLV-MVDFGMCRKYL-- .. ... ||. |. .|...|.| |..| .| | ||||| .| | |. ||| |..||. .|||||||| ||.. | . |. | ..||| .|. GIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMC-NRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDM -NDG ..| DKTG |
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| Kinase | F41G3.5.AA | CK1-Unclassified | 128-167 | 47 | 2.8e-10 | 26.56 | In-house | 178-217 (244) | Show / Hide |
Range on Protein: 128-167 Range on HMM: 178-217/244 Sequence Identity: 47% (19 aa) GTVRYAPLATHYGRDSCRKEDLETIFYVLVELLVGTLPWM || ||| . .|.| |. ||| . |||. .| |.|||. GTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQ |
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| Kinase | F41G3.5.AA | S_TKc | 3-203 | 13 | 4.5e-08 | -58.46 | SMART | 13-231 (231) | Show / Hide |
Range on Protein: 3-203 Range on HMM: 13-231/231 Sequence Identity: 13% (35 aa) AVVLRSLLPI-----------------------RSPYFCRVFFCGKAEKFNFLIMTLVGK---NLSELRANCPNRK----FSRRTGLQIGIQMINAIQQL ..| . . |. .. . . .. ...| ... .| .. ... .. |. . . |...|.. . GKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYC HSIGFIHRDIKPANFCINLDNPHQLVMVDFGMCRKYLNDGGTQLRHPRWSVHGFRGTVRYAPLATHYGRDSCRKEDLETIFY----------VLVELLVG || |.||||.||.| .. .. |||..|.. . | || | . . .| |.|.| HSHGIIHRDLKPENILLDE----HIKICDFGLARQL---------------TTFCGTPWYMAPEVL------------GYGKCKCDWWSCGCILYEMLCG TLPWMTMEEHIHVEHSKQVARTTGLREFLSGCPKQ----------LV-------HILL |. .... | . . ...|...| . | | . YPPFP----QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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| Kinase | F41G3.5.AA | Pkinase | 64-115 | 33 | 2.9e-07 | 26.79 | Pfam | 116-169 (293) | Show / Hide |
Range on Protein: 64-115 Range on HMM: 116-169/293 Sequence Identity: 33% (19 aa) QMINAIQQLHSIGFIHRDIKPANFCINLDNPHQ---LVMVDFGMCRK--YLNDGGTQ |.. ... .|| |.||||.||.|. |. .|.| . ||| ... | |.. .. QILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MT |
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| Kinase | F41G3.5.AA | CK1 | 183-217 | 27 | 3e-06 | 17.52 | In-house | 236-271 (271) | Show / Hide |
Range on Protein: 183-217 Range on HMM: 236-271/271 Sequence Identity: 27% (10 aa) RTTGLREFLSG-CPKQLVHILLYIDNLRFYDAPDYA ..| . . .| .|.... | |. .|.|...|||. MSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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