Gene 13217 (Tetrahymena)

13217

Species: Tetrahymena
Alias: 448, 13217, 4.m00616, TTHERM_00069270, 3707.m00252, PreTt13217
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
13217.AA Protein None 1028 None Fasta, JSON
13217.kin_dom Protein Kinase Domain None 175 None Fasta, JSON
13217.NA RNA None 3087 None Fasta, JSON

Protein domain

Protein domains of 13217.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13217.AA Ciliate-A2 38-169 44 4.2e-24 80.72 In-house 9-145 (272) Show / Hide 
Range on Protein: 38-169
Range on HMM: 9-145/272
Sequence Identity: 44% (61 aa)

IFVEE-DNNTFIKYALKIQNIAVEGSGEIDQLKLLKCKNGVQFIKDCCHQSIGEVVDEFVIEKYHFTQFQDI-FCSLNDWVR--QNQGRKISDYKFVSFA
||||. ||.   |||.|||.|  .  . |.| ||  ||   || | | |. | .. |||.|  |.| |      |||.||.   |||...|.|  ||.||
IFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIPDHQFVHFA

GKILDGLEFIHEKQCFLKDISLDTLLINKDDE-VKIC
  |||..| .|.|.  | |.||   ||..|.. .| |
CQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLC
Kinase 13217.AA Ciliate-A2 194-282 30 1.2e-20 68.53 In-house 173-272 (272) Show / Hide 
Range on Protein: 194-282
Range on HMM: 173-272/272
Sequence Identity: 30% (30 aa)

YKPPEYIEK-------IYNKESYNYTKQGDIWSYGACLSFLGGGQIKQVQKNK---NESQFMITYCHNISKKSNEFVKFILNIDPLKRP-NLREIRDKLN
|.||| ...       . .|.    |..|||| .| ||. |||...... | .   ..  . . .  | ..| |   ..||| || ||| .  .||....
YYPPECHFQCFEMNGEQNKKQQIKQTFMGDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH
Kinase 13217.AA Ciliate-E6 77-221 26 6.6e-15 44.17 In-house 1-154 (154) Show / Hide 
Range on Protein: 77-221
Range on HMM: 1-154/154
Sequence Identity: 26% (42 aa)

VQFIKDCCHQSIGEVVDEFVIEKYHFTQFQDIFCSLNDWVRQNQGRKISDYK--FVSFAGKILDGLEFIHEKQCFLKDISLDTLLINKDDEVKICSVCQD
.|..| | |..|    |.| ||.|.| .. .   .| ||. |.. .|. . .  |. |.  .. ..| .| |  .|  |.|    . |.  .|||   . 
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICD-FGF

SSDLISLQNQSQNFIQ-----SLPYKPP-EYI---EKIYNKESYNYTKQGDIWSYG
..  |..| |.. |        ..| ||  ..   ...   .  | |. ||||| .
QQCIIPNQ-QTKEFMAQKNQNKYHYCPPEQFDYSKDQQSKHYKVNWTQEGDIWSVC
Kinase 13217.AA S_TKc 37-285 17 1.7e-09 -37.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 37-285
Range on HMM: 1-231/231
Sequence Identity: 17% (50 aa)

YIFVEE-------------DNNTFIKYALKIQNIAVEGSGEIDQLKLLKCKNGVQFIKDCCHQSIGEVVDEFVIEKYHFTQFQDI-FCSLNDWVRQNQGR
| ....             ...|  ..|.|| .       ||. ||  ...| |...  . .            . | .. . |    .| |  ......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDYIKKRGRH

K----ISDYKFVSFAGKILDGLEFIHEKQCFLKDISLDTLLINKDDEVKIC---SVCQDSSDLISLQNQSQNFIQSLPYKPPEYIEKIYNKESYNYTK-Q
.    ..     ...  |...||..|...    |.  . .|...  ..|||   . .|              |. .. | .|| .          |.|  
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---------GYGKCK

GDIWSYGACLSFLGGGQI----KQVQKNKNESQFMITYCHNISKKSNEFVKFILNIDPLKRPNLREIRD-----KLNSFF
 |.|| | .|  .  |.      |.  .|             |.   .|.. .|. || |||   |.       |.  .|
CDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13217.AA Ciliate-C8 136-224 18 1.7e-07 23.24 In-house 128-238 (238) Show / Hide 
Range on Protein: 136-224
Range on HMM: 128-238/238
Sequence Identity: 18% (20 aa)

ILDGLEFIHEKQCFLKDISLDTLLINKD----DEVKIC-----------SVCQDSSDLISLQN--QSQNFIQS-----LPYKPPEYIEKIYNKESYNYTK
..|.. ..| ..    || .. .| . |     ..|.|           |  ... . .. ..  ...  |..     . | .|| ..|.. ..|  ..|
MIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSK

QGDIWSYGACL
. |..| | .|
KSDSYSVGLVL
Kinase 13217.AA Ciliate-C7 35-160 22 7e-07 18.61 In-house 9-135 (164) Show / Hide 
Range on Protein: 35-160
Range on HMM: 9-135/164
Sequence Identity: 22% (29 aa)

QSYIFVEEDNNTFIKYALKIQNIAVEGSGEIDQLKLLKCKNGVQFIKDCCHQSIG-EVVDEFVIEKYHFTQFQDIFC-SLNDWVRQNQGRKISDYKFVSF
|.  .. .|..| . || |  ..    .|.|||  . .... .. .| |  .. .   ...|  ... . .   ..  .||. . .||  . . . .. .
QGLVLLAKDQKTNMRYAIKGVQVR-DKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLNEISAIKY

AGKILDGLEFIHEKQCFLKDISLDTLLI
|  |  || .||.|.| ..|...|  ||
AKDIAQGLYYIHSKNCVVNDLKMDNILI
Kinase 13217.AA Ciliate-E2-Unclassified 113-277 17 2e-06 18.6 In-house 123-346 (352) Show / Hide 
Range on Protein: 113-277
Range on HMM: 123-346/352
Sequence Identity: 17% (39 aa)

NDWVRQNQGRK-ISDYKFV-----SFAGKILDGLEFIHEKQ-CFLKDISLDTLLINKDD---EVKICS--VCQDSSDL------------ISLQNQSQNF
|| ..... || ..... .      ..  ||.|||..|.|. .   || .. .|....    ..||.    .  . .             |  |. .. |
NDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTF

IQSLPYK----PPEYIEK-IYNKESYNYTKQGDIWSYGACLSFLGGGQIKQVQKNKNE--------------SQFMITYC---------------HNISK
.... |.    .||....  |....    .. |||| | .| ..  |.    ..|...              .|.    .               ...|.
CGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSP

KSNEFVK----FILNIDPLKRPNLREI
.  .|..     .|. .| ||... .|
EAKDFINDLLQKMLKKNPNKRITFEQI
Kinase 13217.AA Ciliate-E2 132-285 17 8e-06 15.92 In-house 165-365 (365) Show / Hide 
Range on Protein: 132-285
Range on HMM: 165-365/365
Sequence Identity: 17% (36 aa)

FAGKILDGLEFIHEKQ-CFLKDISLDTLLINKDDEVKIC--SVCQDSSDL----------------------------ISLQNQSQNFIQSLPYKPPEYI
... |...||..|.|  ..  || .. .|.     .||.    ... .|                             |  ||. .... ...|..|| .
YIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEIL

EKIY---NKESYNYTKQGDIWSYGACLSFLGGGQIKQVQKNKNESQFMITYC------------------HNISKKSNEFVKF----ILNIDPLKRPN-L
..     ....  |... |||| | .| ..  |.       ..  |  | .                   ...|..   . |     .|. || ||..  
NGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGW

REIRDKLNSFF
 .|  . . .|
EQI--LNHPWF
Kinase 13217.AA ASK 135-221 32 5.9e-05 12.21 In-house 102-184 (254) Show / Hide 
Range on Protein: 135-221
Range on HMM: 102-184/254
Sequence Identity: 32% (28 aa)

KILDGLEFIHEKQCFLKDISLDTLLINKDDEVKICSVCQDSSDLISLQNQSQNFIQSLPYKPPEYIEKIYNKESYNYTKQGDIWSYG
.||.||...||.|   .||  |  |.|    |   |    .  |  ..  .. |   | |  || |.    .    | |  ||||.|
QILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTETFTGTLQYMAPEVID----QGQRGYGKPADIWSFG
Kinase 13217.AA C8 117-224 21 0.000102 12.43 In-house 113-226 (226) Show / Hide 
Range on Protein: 117-224
Range on HMM: 113-226/226
Sequence Identity: 21% (25 aa)

RQNQGRKISDYKFVSFAGKILDGLEFIHEKQCFLKDISLDTLLINKDDEVK-ICSVCQ-DSSDLISLQNQSQNFIQ-----SLPYKPPEYIEKIYNKESY
|.|.  ..|. .    | ...||...|| |.   .|| .. .|.  | .   .   |  . .. .|   ..   ..      . |  || ..|  ...  
RRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKK-QDNQYK

NYTKQGDIWSYGACL
 |..| |..| |  |
QYRIQSDLFSVGLVL
Kinase 13217.AA PLK-Unclassified 251-285 28 0.000121 13.62 In-house 232-264 (264) Show / Hide 
Range on Protein: 251-285
Range on HMM: 232-264/264
Sequence Identity: 28% (10 aa)

NISKKSNEFVKFILNIDPLKRPNLREIRDKLNSFF
.||..   ... |||..| .||.. .|  .  .|.
HISDNAKDLIQHILNWNPDQRPTIDQI--MMHPFY
Kinase 13217.AA Ciliate-C3 135-171 35 0.000137 12.81 In-house 104-140 (140) Show / Hide 
Range on Protein: 135-171
Range on HMM: 104-140/140
Sequence Identity: 35% (13 aa)

KILDGLEFIHEKQCFLKDISLDTLLINKDDEVKICSV
.||  ....||      || .  .|||  ||.||   
QILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase 13217.AA TyrKc 52-281 16 0.000253 -152.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 52-281
Range on HMM: 1-280/280
Sequence Identity: 16% (49 aa)

LKIQNIAVEGS-GEIDQLKLLKCKNGVQ-FIKDCCHQSIGEVVDEFVIEKYHFTQF------------------------QDIFC--------SLNDWVR
..   .  ||  ||. . ..      .|  .| . . .    . .|  |    ...                        . ..         .|.|  |
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QNQGRKISDYKFVSFAGKILDGLEFIHEKQCFLKDISLDTLLINKDDEVKIC----SVCQDSSDLISLQNQSQNFI----QS---LPYK--PPEYIEKIY
 .... ..  ...||.  | .| |..|.|.|   |.     |....  |||.    |   .. |     ...        ..   ||..  .|| |    
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWMAPECI----

NKESYN-YTKQGDIWSYGACL-------SFLGGGQIKQVQKNKNESQFMITY--CHNISK--------KSNEFVKFIL---NIDPLKRPNLREIRDKL
    |. .| . |.||.| |.            |.|.|. .|.   ..  .                  . |  . ..   . || .||. .||....
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF