Gene 26360 (Tetrahymena)

26360

Species: Tetrahymena
Alias: 1147, TTHERM_01162050, n.26360, PreTt26360, 259.m00044, 26360
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
26360.AA Protein None 584 None Fasta, JSON
26360.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
26360.NA RNA None 1755 None Fasta, JSON

Protein domain

Protein domains of 26360.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26360.AA Ciliate-A2 31-154 33 4.2e-22 73.68 In-house 15-144 (272) Show / Hide 
Range on Protein: 31-154
Range on HMM: 15-144/272
Sequence Identity: 33% (43 aa)

D-DKNNEYNLKIINMFDGVNN-IDKTIYQNAQQEVKVMKTFNHKNVLKVVDYFEIGYYFLIVTERY-ESSLEQWLR--SRQTNQLFLPQIISFSDQLFQA
| ..| .|..||.. .|| .  |..   |... | ...|  ||.|. |. | | || |  |..| . |.||..|    . |.. .   |...|  |. .|
DNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIPDHQFVHFACQILDA

LEHIHSKKKEARDIDLSTIMIDKNNQ-LKV
.|..|.|    ||. |  | ||..|| .|.
IEYLHNKNYVLRDLSLRNILIDQDNQIIKL
Kinase 26360.AA Ciliate-E6 63-133 35 6.1e-15 44.28 In-house 1-73 (154) Show / Hide 
Range on Protein: 63-133
Range on HMM: 1-73/154
Sequence Identity: 35% (26 aa)

VKVMKTFNHKNVLKVVDYFEIGYYFLIVTERYESSLEQWLRSRQTNQLFLPQ--IISFSDQLFQALEHIHSKK
..  |  ||.| ||  | | |  |..|| || | .|..|.   . .. .      . |. |||.|.|..|||.
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKN
Kinase 26360.AA CMGC 62-133 15 5.7e-11 31.33 In-house 71-202 (513) Show / Hide 
Range on Protein: 62-133
Range on HMM: 71-202/513
Sequence Identity: 15% (21 aa)

EVKVMKTFN-----------------HKNVLKVVDYFEIGY-----------------YFLIVTERYESSLEQWLRSRQT-------NQLFLPQ------
|.| .| .|                 |.|..|  |.|                     .. .|.|  . .| | ... |.       . |   .      
EIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPH

------IISFS------DQLFQALE--HIHSKK
      | .|.       |....|.  ..||..
RRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHW
Kinase 26360.AA Ciliate-E2 32-133 17 8e-08 22.92 In-house 45-180 (365) Show / Hide 
Range on Protein: 32-133
Range on HMM: 45-180/365
Sequence Identity: 17% (24 aa)

DKNNEYNLKII--NMFDGVNNIDKTI------YQNAQQEVKVMKTFNHKNVLKVVDYFE--IGYYFLIVTERYES-SLEQWLRSRQTNQLFL--------
.|...|..||.  |.   ...... .      |    .| ..... ||.|..| ...|.     .. .|.| ..  .|.............         
VKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFT

-PQIISFSDQLFQ---------------ALEHIHSKK
  .|. .. |..|               |||..|||.
EKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN
Kinase 26360.AA PASK 62-92 38 1.3e-07 19.53 In-house 54-87 (260) Show / Hide 
Range on Protein: 62-92
Range on HMM: 54-87/260
Sequence Identity: 38% (13 aa)

EVKVMKTFN---HKNVLKVVDYFEIGYYFLIVTE
|...| | |   |.|..||.| ||   .. .|.|
EIHIMQTLNKNPHENIVKVLDFFENDDFYQLVME
Kinase 26360.AA Pkinase 61-133 22 2.4e-07 27.05 Pfam 49-128 (293) Show / Hide 
Range on Protein: 61-133
Range on HMM: 49-128/293
Sequence Identity: 22% (18 aa)

QEVKVMKTFNHKNVLKVVDYFEIGYYFLIVTERYES-----SLEQWLRSRQTNQL--FLPQIISFSDQLFQALEHIHSKK
.|...|| .||.|...  |.|| . .  .|.|  |      .|  ... .. . .     .....  |....||..||..
SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMG
S_TKc 26360.AA S_TKc 11-220 13 5.8e-07 -74.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-220
Range on HMM: 1-231/231
Sequence Identity: 13% (37 aa)

FFQIKDLAE------KLYHEQRAVVSDDKNNEYNLKIINMFDGVNNIDKTIYQNAQQEVKVMKTFNHKNVLKVVDYFEIGYYFLIVTERYES---SLEQW
.  .. . .      .. .. .       . .. .|||.             .....|....|  .|.|. |  |.|.   .. .|.|  .    .| . 
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

LRSRQT----NQLFLPQIISFSDQLFQALEHIHSKKKEARDIDLSTIMIDKNNQLKV----------------------VCNGYFNA-------------
...|..     ..   .. ..  |...|||..||..   ||.  . |..|.  ..|.                      |.   ..              
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

------NIFRRVQSLQIQNQKNKISLLYNVNQQISENEIDMTQNILKVDKTKLKQIDVLA-------SIQI
        |.     |.|   .||          |.  .|. ...|..| .|   ...|.          .
EMLCGYPPFP-----QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 26360.AA Ciliate-E2a 49-133 19 6.8e-07 16.35 In-house 36-122 (275) Show / Hide 
Range on Protein: 49-133
Range on HMM: 36-122/275
Sequence Identity: 19% (17 aa)

NNIDKTIYQNAQQEVKVMKTFNHKNVLKVVDYFEIGYYFLIVTERYES-SLEQWLRSRQTNQLFLPQIISFSDQLF-QALEHIHSKK
....|. ... ..|.. |.. .|.|..|  ...|   .. .|.| .|. .|.. ..  .... .  .| ..  ||. |.|...|...
MYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRN
Kinase 26360.AA Ciliate-C7 31-177 26 1e-06 17.55 In-house 17-164 (164) Show / Hide 
Range on Protein: 31-177
Range on HMM: 17-164/164
Sequence Identity: 26% (39 aa)

DDKNN-EYNLKIINMFDGVNNIDKTIYQNAQQEVKVMKT-FNHKNVLKVVDYFE-IGYYFLIVTERYESSLEQWLRSRQTNQLFLPQIISFSDQLFQALE
| |.|  |  | ..  |   |||. |.. .|||....|    . .|.. ...||   ...|. .|  . .|.| . . | . |     | ..    | | 
DQKTNMRYAIKGVQVRDKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLNEISAIKYAKDIAQGLY

HIHSKKKEARDIDLSTIMIDKNNQLKVVCNGYFNANIFRRVQSLQIQNQK
.||||.  ..|. .. | || |.  .|    .  |. ..  .  || .. 
YIHSKNCVVNDLKMDNILIDYNGNAVVC--DFGLADNLTQKSKYQINQYM
Kinase 26360.AA CAMK 40-133 14 9e-06 13.86 In-house 37-199 (425) Show / Hide 
Range on Protein: 40-133
Range on HMM: 37-199/425
Sequence Identity: 14% (23 aa)

KIINMFDGVNN----------IDKT------------IYQNAQQEVKVMKT-------FNHKNVLKVVDYFE---------IGY-----------YFLIV
|||.     ..          |||.              .| ..|...||.        .|.|..|  ...|         . |           .. .|
KIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMV

T---ERYESS-LEQWLRSRQTNQ-----------------LFLPQIISFSDQLFQALEHIHSKK
.   |  .   | . | .. . .                 .   .   .  |. .|....||..
MEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
Kinase 26360.AA CAMK-Unique 62-133 16 9e-06 14.82 In-house 66-177 (363) Show / Hide 
Range on Protein: 62-133
Range on HMM: 66-177/363
Sequence Identity: 16% (18 aa)

EVKVMKTFNHKNVLKVVDY----FEIGY---------------YFLIVTERYESS-LEQWLRSR-----------------QTNQLFLP---QIISFSDQ
|. ..|. .| | .|..|.    |.                  |. ||.|. .   | .|. ..                 . .. |     .... . .
EHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQC

LFQALEHIHSKK
| .|... ||..
LLSAVAYMHSQD
Kinase 26360.AA Ciliate-B2 57-132 30 1.1e-05 9.27 In-house 44-123 (197) Show / Hide 
Range on Protein: 57-132
Range on HMM: 44-123/197
Sequence Identity: 30% (25 aa)

QNAQQEVKVMKTFN-HKNVLKVVDYFEIGYYF-LIVTERYESSLEQWLR--SRQT---NQLFLPQIISFSDQLFQALEHIHSK
...|.|.|.|| |. . || |..|...|      ...|. | ||.| |    .|    |.  | |.|    ||. .|  ....
EEIQHEIKIMKMFEYNINVVKYIDHIQINETIDVLIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIF---QLIDGLIQFRMY
TPR_2 26360.AA TPR_2 290-323 23 0.011715 13.49 Pfam 1-34 (34) Show / Hide 
Range on Protein: 290-323
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

PQYYQAVGDFYKSIQKYDDSAQAYKKCLQEGKEN
. .. . |. |   ..||. ...|.|.|.   .|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 26360.AA TPR_2 469-502 38 0.000172 19.98 Pfam 1-34 (34) Show / Hide 
Range on Protein: 469-502
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

GFCYVHLANYYQHQFKYNEAIQIMDKCLKSLPNN
  ..  |.. | .| .| |||. ..|.||  |||
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN