Gene 14987 (Tetrahymena)

14987

Species: Tetrahymena
Alias: 155.m00107, PreTt14987, 1192, 14987, TTHERM_00875870
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
14987.AA Protein None 428 None Fasta, JSON
14987.kin_dom Protein Kinase Domain None 85 None Fasta, JSON
14987.NA RNA None 1287 None Fasta, JSON

Protein domain

Protein domains of 14987.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 14987.AA Ciliate-A8 30-114 45 8.8e-28 93.23 In-house 1-85 (151) Show / Hide 
Range on Protein: 30-114
Range on HMM: 1-85/151
Sequence Identity: 45% (39 aa)

YEYLKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEYNLGLLAIVMELCD
|.| | ||.|| |.||.| |...| |||.||||    .|..|    .|.||..|... | |.|.| |.|.  ..|. |||.|.||
YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCD
Kinase 14987.AA Ciliate-E1 36-127 26 1.9e-19 60.24 In-house 1-99 (202) Show / Hide 
Range on Protein: 36-127
Range on HMM: 1-99/202
Sequence Identity: 26% (26 aa)

LEQGDSSLVVVAFSQKLQ-YQVAVKIIKTRGAINQVNLLQVDKEIQ-ILQNLQSEMYVLKIFEKIE-EYNLGLLAIVMELCDYLFYINQ-----IIIQKL
...|..|.|. |..|. . .|||.|||......||...... ||.. |.. ...|.|...|.. |. ..|.. ..|....|. |.  .|     ...|..
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC
Kinase 14987.AA CAMK 35-114 14 2.5e-08 22.19 In-house 1-143 (425) Show / Hide 
Range on Protein: 35-114
Range on HMM: 1-143/425
Sequence Identity: 14% (21 aa)

MLEQGDSSLVVVAFSQKLQ------------YQVAVKIIKTRGAIN-------------------------QVNLLQVDKEIQILQNLQ------SEMYV
 | .|  . |  ..  . .             .||.|||... . .                         .... .| .||.|...||      .   .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKIFEKIEE-------YNLG-----------LLAIVM---ELCD
.|..| .|           .            . .||   |.|.
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCS
Kinase 14987.AA S_TKc 30-223 15 6e-08 -60.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-223
Range on HMM: 1-231/231
Sequence Identity: 15% (41 aa)

YEYLKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEYNLGLLAIVMELCDY-----LFYINQIII
|| |. . .|  . |  .   | . .||.||||           .. .|||||..     .. |... ...   . | .|||.||      . || .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

------QKLPSISDISSEMT-----------------------NEQRLK---------------------------SL-YSDVFSIGLILTEAFISRQLS
           .  .  ..                        .| ..|                           .   .|. |.| || | .  . . 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPF

PEELKNLKSQIIFNVFPFLNNYENIRFFDKILLKMIDQNQDLRLLPKDLLY------NLKAF
| ... .  .|               . | .. |. . . . |.   ..|       .   |
P-QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 14987.AA CAMKL 30-114 24 1.1e-07 20.39 In-house 1-104 (297) Show / Hide 
Range on Protein: 30-114
Range on HMM: 1-104/297
Sequence Identity: 24% (26 aa)

YEYLKMLEQGDSSLVVVAFSQKL-QYQVAVKIIKTRGAINQVNLLQ------------VDKEIQILQNLQ--SEMYVLKIFEKIE--EY---NLGLLAIV
|. .| | .|  . |  |  ... . .||.|||. ... |  . ..            . .||||.. |.      . |..| ||  |.   . . . .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

MELCD
||.|.
MEYCS
Kinase 14987.AA Ciliate-E5 34-126 26 4.9e-07 18.72 In-house 5-97 (271) Show / Hide 
Range on Protein: 34-126
Range on HMM: 5-97/271
Sequence Identity: 26% (26 aa)

KMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEY--NLGLLAIVMELCDY--LFYINQIIIQK
..| .| | .|. ..|  ... .| ||.|    .|| .. .  .| .||....|  ...| .. ....  |. .. |.||.| .    |.|.|| |.
QILGKGGSGMVMKGCSEWNDKPIAIKIMK---CKNQKQCEDNQREFNILKQFNSP-HIIKVYQIYQYQYENMNYQFIIMERCKCDLHTYLNKIIYQM
Kinase 14987.AA Ciliate-C7 33-99 32 2e-06 17.35 In-house 1-70 (164) Show / Hide 
Range on Protein: 33-99
Range on HMM: 1-70/164
Sequence Identity: 32% (23 aa)

LKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTR---GAINQVNLLQVDKEIQILQNLQSEMYVLKIFEKIE
.. | ||  .||..|  || .   |.| .. |   | |.|  . || .||.||.. .   ||.......|
FRFLGQGQQGLVLLAKDQKTNMRYAIKGVQVRDKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFE
Kinase 14987.AA CMGC 30-115 15 8e-06 14.1 In-house 1-139 (513) Show / Hide 
Range on Protein: 30-115
Range on HMM: 1-139/513
Sequence Identity: 15% (22 aa)

YEYLKMLEQGDSSLVVVAFSQKLQYQ--------------VAVKIIK----TRGAI----NQVNLLQVDKEIQILQNLQ----------------SEMYV
|| .| . .|  . |. .. .. . .              ||.|.||    ...|       .       ||.||..|.                 . ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

LKIFEKIEEYN---------------LGLLAIVMELCDY
.|... .   |               .  | .|.|..|.
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH
Kinase 14987.AA Ciliate-E3 30-113 24 5.5e-05 11.83 In-house 1-86 (202) Show / Hide 
Range on Protein: 30-113
Range on HMM: 1-86/202
Sequence Identity: 24% (21 aa)

YEYLKMLEQGDSSLVVVAFSQKLQYQVAVKIIKTRGAIN---QVNLLQVDKEIQILQNLQSEMYVLKIFEKIEEYNLGLLAIVMELC
|  .. | .|  ..|  ||.. .  .|| | | ..   |     ..  . .|.|  | . |. .|.|. . .   .. .. ||.|.|
YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAIICQNQQNEGVGEQFQKTQQEFQNCQQINSQ-NVVKCHDQYYDQQNKMIFIVQEYC
Kinase 14987.AA JNK 30-59 40 0.000116 13.37 In-house 1-30 (309) Show / Hide 
Range on Protein: 30-59
Range on HMM: 1-30/309
Sequence Identity: 40% (12 aa)

YEYLKMLEQGDSSLVVVAFSQKLQYQVAVK
|  ||.. ||.  .|. || | .. .||.|
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIK
Kinase 14987.AA STE 30-88 13 0.000388 10.65 In-house 1-90 (359) Show / Hide 
Range on Protein: 30-88
Range on HMM: 1-90/359
Sequence Identity: 13% (12 aa)

YEYLKMLEQGDSSLVVVA---------FSQKL------QYQVAVKIIKTRGA--------------INQVNLLQVDKEIQILQNLQ--SE
.| .... .| .  |. |          ....      .  .|.|... .                .|. .. |. |||.|.....  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHP