24905

Species: Tetrahymena
Alias: TTHERM_00390090, 70, 41.m00312, PreTt24905, 24905
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
24905.AA Protein None 494 None Fasta, JSON
24905.kin_dom Protein Kinase Domain None 83 None Fasta, JSON
24905.NA RNA None 1485 None Fasta, JSON

Protein domain

Protein domains of 24905.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 24905.AA Ciliate-E1 40-123 30 1e-18 57.84 In-house 1-88 (202) Show / Hide
Range on Protein: 40-123
Range on HMM: 1-88/202
Sequence Identity: 30% (27 aa)

IGHGCYTETFTAFQANNNQIVVIKVLIDMN---NKEYIDAFTKEKN-LLKTIKNNKYSLQIIDDLE-DKNLDFAAIVVEHCDSDFRQSQ
||.|..   | |.| |||...|....| ..   |.....  .|| . ..| .|...|..|||| .. |.|. ...|. ..|.|.... |
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQ

Kinase 24905.AA Ciliate-A8 34-119 35 3.4e-18 59.91 In-house 1-89 (151) Show / Hide
Range on Protein: 34-119
Range on HMM: 1-89/151
Sequence Identity: 35% (32 aa)

YVILQKIGHGCYTETFTAFQANNNQIVVIKVLIDMNNKEYIDA--FTKEKNLLKTIKNNKYSLQIIDDLEDKNLDFAAIVVEHCDS-DF
|..  ... |   . . | . | ...|.||....||.   | .  | |... .  ||| || ||||....||.. | ||| | ||. ||
YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDF

Kinase 24905.AA CK2 34-65 41 2.2e-09 23.41 In-house 1-34 (288) Show / Hide
Range on Protein: 34-65
Range on HMM: 1-34/288
Sequence Identity: 41% (14 aa)

YVILQKIGHGCYTETFTAFQANNNQIV--VIKVL
| . .||| | | | | ... .||. .  |||.|
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKIL

Kinase 24905.AA S_TKc 34-239 15 2.6e-09 -40.48 SMART 1-231 (231) Show / Hide
Range on Protein: 34-239
Range on HMM: 1-231/231
Sequence Identity: 15% (43 aa)

YVILQKIGHGCYTETFTAFQANNNQIVVIKVLIDMNNKEYIDAFTKEKNLLKTIKNNKYSLQIIDDLEDKNLDFAAIVVEHCDS------DFRQSQ----
| ||.|||.| . . . .   . ..|| ||..         . . .| ..||   . ..  ...|  .|   |.  .| |.||       |. ...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--------------------------------------------------ISSQNQKQSSGNDQYFYGDQCYRSPEVLNQQKPPYTFKKADVFSIGQLLV
                                                  .. |           | |   |..||||     .|...|.|. |.| .| 
LRFPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILY

EVFLQRKLSVNESMNLKQKSLFEAIPDLKNYQNNTFINDILINMANPNQDQRLEPFELLQ-----NMQKFT
| .  ..          .. .|. |          ... .. .. . . ..|.   |.||     ..  . 
EMLC-GYPPFP-----QMQMMFKKIG------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 24905.AA ULK 34-121 17 3.8e-08 24.62 In-house 1-109 (329) Show / Hide
Range on Protein: 34-121
Range on HMM: 1-109/329
Sequence Identity: 17% (20 aa)

YVILQKIGHGCYTETFTAFQA----NN---NQIVVIKVLI----DMNNKEY-----IDAFTKEKNLLKTIK---NNKY----SLQIIDDLEDKNLDFAAI
|.. ...|.| .    . ...    ..   |..|..|..     ...|.|.     .. ...|  ..|..|   ..|.      . .| .|..| .   |
YCLNHCLGKGSFG---KVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYI

VVEHCDS-DFRQ
..| |.  |..|
IMEYCNGGDLEQ

Kinase 24905.AA PASK 34-63 30 9.3e-08 19.94 In-house 1-30 (260) Show / Hide
Range on Protein: 34-63
Range on HMM: 1-30/260
Sequence Identity: 30% (9 aa)

YVILQKIGHGCYTETFTAFQANNNQIVVIK
|...|..| | |    ....  .. |||.|
YTSIQQMGEGAYGYVWMCIHNECRYIVVVK

Kinase 24905.AA ULK 34-116 19 3.3e-07 21.69 In-house 1-100 (324) Show / Hide
Range on Protein: 34-116
Range on HMM: 1-100/324
Sequence Identity: 19% (20 aa)

YVILQKIGHGCYTETFTAFQA----NN--NQIVVIKVLI--DMNNKEY-------IDAFTKEKNLLKTIK--NNKY--SLQIIDDLEDKNLDFAAIVVEH
|.. ...|.| .   .. ...    .|  ||.| .|.     ||.|..       .. . .| ...|..|  ....    . .| .|..| ..  |..| 
YCLNHCLGKGSFG--VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEY

CD
|.
CN

Kinase 24905.AA KHS 34-88 23 1.6e-05 14.43 In-house 1-54 (258) Show / Hide
Range on Protein: 34-88
Range on HMM: 1-54/258
Sequence Identity: 23% (13 aa)

YVILQKIGHGCYTETFTAFQANNNQIVVIKVLIDMNNKEYIDAFTKEKNLLKTIK
| .||..| | | . . | . . .... .|| | |.  . .    .|  ..|. .
YELLQRVGSGTYGDVYKARDIQSDELAAVKV-IKMEPGDDFAVIQQEIMMMKDCR

Kinase 24905.AA MAPK 34-63 30 2.1e-05 14.37 In-house 1-36 (328) Show / Hide
Range on Protein: 34-63
Range on HMM: 1-36/328
Sequence Identity: 30% (11 aa)

YVILQKIGHGCYTETFTAFQAN------NNQIVVIK
|.||..||.| |   . |..        ....|.||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK

Kinase 24905.AA CMGC 34-65 26 2.7e-05 12.35 In-house 1-46 (513) Show / Hide
Range on Protein: 34-65
Range on HMM: 1-46/513
Sequence Identity: 26% (12 aa)

YVILQKIGHGCYTETFTAFQ--------------ANNNQIVVIKVL
| |..|||.| | . . ..                ..|.|| || .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKI

Kinase 24905.AA Ciliate-C8 115-172 28 3.4e-05 14.93 In-house 165-238 (238) Show / Hide
Range on Protein: 115-172
Range on HMM: 165-238/238
Sequence Identity: 28% (21 aa)

CD----SDFRQSQISSQNQK-----QSSGNDQY----FYGDQCYRSPEVLNQ----QKPPYTFKKADVFSIGQLL
||     || ..   ..|.      .  | |||    |.|   |  |||...    |   ...|  |..| | .|
CDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKK-SDSYSVGLVL

Kinase 24905.AA ULK 147-169 36 0.000385 10.66 In-house 215-239 (324) Show / Hide
Range on Protein: 147-169
Range on HMM: 215-239/324
Sequence Identity: 36% (9 aa)

SPEVLNQQ--KPPYTFKKADVFSIG
.|..|..|  . ||. .|.|..|.|
APQILQGQGEQKPYYDYKCDIWSLG

Kinase 24905.AA ULK 147-169 36 0.000396 10.41 In-house 219-243 (329) Show / Hide
Range on Protein: 147-169
Range on HMM: 219-243/329
Sequence Identity: 36% (9 aa)

SPEVLNQQ--KPPYTFKKADVFSIG
.|..|..|  . ||. .|.|..|.|
APQILQGQGEQKPYYDYKCDIWSLG

Kinase 24905.AA Ciliate-E1 125-166 26 0.004033 6.56 In-house 162-202 (202) Show / Hide
Range on Protein: 125-166
Range on HMM: 162-202/202
Sequence Identity: 26% (11 aa)

SSQNQKQSSGNDQYFYGDQCYRSPEVLNQQKPPYTFKKADVF
....|.| .|  .|.|  ..| .||. . .|.    .| |..
NQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY

LRR_RI 24905.AA LRR_RI 323-350 25 0.365912 1.62 SMART 1-28 (28) Show / Hide
Range on Protein: 323-350
Range on HMM: 1-28/28
Sequence Identity: 25% (7 aa)

DCQEVELKYRSNQINEEGAKAIGISLEE
 |   ||  ..| . .||....  .|..
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 24905.AA LRR_RI 353-380 39 0.003965 15.49 SMART 1-28 (28) Show / Hide
Range on Protein: 353-380
Range on HMM: 1-28/28
Sequence Identity: 39% (11 aa)

NISLLNLILKNNNFSAEGVKILGTHLEQ
| ||. | | ||.. .||.. |   |..
NCSLRELWLSNNKLGDEGCRQLCEGLKH

LRR_RI 24905.AA LRR_RI 383-410 32 0.000301 21.36 SMART 1-28 (28) Show / Hide
Range on Protein: 383-410
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NISFLDLNLGNNNIGERGVKAIGTSLEQ
| | . |.|.||..|. |....  .|..
NCSLRELWLSNNKLGDEGCRQLCEGLKH