Gene 22504 (Tetrahymena)

22504

Species: Tetrahymena
Alias: 22504, 628, PreTt22504, TTHERM_00470900, 56.m00208, 3686.m00051
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
22504.AA Protein None 420 None Fasta, JSON
22504.kin_dom Protein Kinase Domain None 262 None Fasta, JSON
22504.NA RNA None 1263 None Fasta, JSON

Protein domain

Protein domains of 22504.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 22504.AA Ciliate-E2-Unclassified 95-356 21 2e-86 293.45 In-house 1-352 (352) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-352/352
Sequence Identity: 21% (78 aa)

YEKLEKIGEGGNSCVHRCRRIND----------DSQHFAVKITKFSNEEIILSETDTSNR----------LLK---LSHPNVCKAYDLFVEKSFNTTYLI
|.....||.||...|..|.....          ..|....|. .... ||.....   |.          ...   |.||. .. ........ .. |..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYINGQTIEQWIQQKQT-----------------IEDNEIR-----FIMNGLLEGIDYLHQQG-FIHRDISSSNVIYDRDCK--KVKIIDLSTCK----
|||..|.. .|.|... .                 .......     |..  .|.|..|||... .|||||  .|...| ..|  ..||||.. .|    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----DNKFS-------PHRKLLTVIGNDIYR----APEMFEG-AYH----QEVDIWAAGLILFQLLFQKHPFF--ESGDDQVVLVQKVTQ-----QEIDW
    | ...       .. .. |..|. .|     |||...|  |      ..|||. | ||...||...||.   . ..|..  |.. .     | ...
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQN

DLLQKTN----------DKVSPCQIDLCQ----EMLKKNPSDRISAKQALRHPFL
 . ....          ...||...|...     ||||||. ||...|.| ||..
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 22504.AA Ciliate-E2 95-356 22 7.1e-78 265.03 In-house 1-365 (365) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YEKLEKIGEGGNSCVHRCRRIND----------------------DSQHFAVKITKFSNEEIILSETDTSN-------------RLLKLSHPNVCKAYDL
|....|||.|. ..| .|.....                      ... .|.|| | .. |.|..| .  .              | .|.|||..| |. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FVEKSFNTTYLIMEYINGQTIEQWIQQKQTIE-----------DNEIRFIMNGLLE---------------GIDYLHQQG-FIHRDISSSNVIYDRDCKK
| ||. |. ||.|||..|.. ...|..... .           ..||..||  .|.               .. |||...  |||||  .|...      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VKIIDLSTCKDNKFS-------PHRKLLTVIG------------------------NDIYRAPEMFEGA----------YHQEVDIWAAGLILFQLLFQK
.||||. ..|... .       ...|...  .                        .  | |||...|           |  ..|||..| ||...|| |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

HPFFESGDDQVVLVQKVTQQEIDWDLLQKT------------NDKVSPCQIDLCQE----MLKKNPSDRIS-AKQALRHPFL
.||           |.  |..|| .  ...            ..|.|.  .||..     ||.|.|. ||. ..|.| ||..
PPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 22504.AA S_TKc 95-356 26 2.7e-66 227.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-231/231
Sequence Identity: 26% (73 aa)

YEKLEKIGEGGNSCVHRCRRINDDSQHFAVKITKFSNEEIILSETDTSNRLLKLSHPNVCKAYDLFVEKSFNTTYLIMEYING--QTIEQWIQQKQT---
||.|.|||.|. ..|..|| .. . ...|.|| |    | |..| .   .     |||..| || |..   .  |..|||..|   .  . |.....   
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IEDNEIRFIMNGLLEGIDYLHQQGFIHRDISSSNVIYDRDCKKVKIIDLSTCKDNKFSPHRKLLTVIGNDIYRAPEMFEGAYHQ-EVDIWAAGLILF
   .   ..||.|  ......|.|..|.||||.  .|.  |.    .||.|   ..           |..|   |.|||..   |   ..|.|. | ||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

QLLFQKHPFFESGDDQVVLVQKVTQQEIDWDLLQKTNDKVSPCQIDLCQEMLKKNPSDRISAKQALR-------HPFL
 .|  . ||     .. .. .|.                 ||  .|. . .|.|.|..|..| .||.       ||..
EMLCGYPPFP----QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 22504.AA Pkinase 95-356 26 1e-52 186.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-293/293
Sequence Identity: 26% (78 aa)

YEKLEKIGEGGNSCVHRCRRINDDSQHFAVKITKFSNEEIILSETDTS----NRLLKLSHPNVCKAYDLFVEKSFNTTYLIMEYINGQ----TIEQWIQ-
|....|||.|. .|| .|.....    .|||| | ..|.    .|..       ...|.|||... || | .   .  |..||| .|         .|. 
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

-QKQTI--EDNEIRFIMNGLLEGIDYLHQQGFIHRDISSSNVIYDRDCKK---VKIID--LSTCKDNKFSPHRKLLTVIGNDIYRAPEM--FEGAYHQEV
 .. ..  ...|..|.|  .|.|..|.|..|.||||. ..|. .|...     |||.|  |. ..|    . . . |. |   |.|||   .   | ..|
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWAAGLILFQLLFQKHPFFES----GDDQVVLVQKVTQQEIDWDLLQKTN---------------DKVSPCQIDLCQEMLKKNPSDRISAKQALRHPFL
|.|..|.||...|. . || ..    ..|| ...... . ....|  .. .               ...|.  .|..  .|.|.|..|..|.|.| ||..
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 22504.AA CAMK 100-356 16 3.8e-51 162.68 In-house 1-425 (425) Show / Hide 
Range on Protein: 100-356
Range on HMM: 1-425/425
Sequence Identity: 16% (72 aa)

KIGEGGNSCVHRCRRINDDS-----------QHFAVKI-------------------TKFS------------NEEIILSETDTSNRLLK----LSHPNV
..|.|. . |..|...|.             |..|.||                    ..|            ... ...| .  ..| .    |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CKAYDLFVEKS--------------FNT----TYLIM---EYINGQ----TIEQWIQQK---------------QTIEDNEIRFIMNGLLEGIDYLHQQG
.| |. .  ..              | |     |..|   ||. |      . ..|...                 ..  | |...  ......|.|...
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

FIHRDISSSNVIYDRDC----------------KKVKIIDLSTCKDNKFSP----------------------HRKLLTVIGNDIYRA-PEMFEG-----
 .|||.   |. .| .                  ..||||    .  . .                         |. |. |   | | ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------AYH-QEVDIWAAGLILFQLLFQKHPFFES-----------GDDQVVLVQKVTQQEIDWDLLQKT----------NDKVSPC--------QI
          |. ...|.|..| ||. .|  . || ..           |...  | .|... . |..  . .           |..|           .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLCQEMLKKNPSDRISAKQALRHPFL
|| . ||...|..|....|.|.||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 22504.AA CMGC 95-356 16 5e-43 138.64 In-house 1-513 (513) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-513/513
Sequence Identity: 16% (87 aa)

YEKLEKIGEGGNSCVHRCRR-------------INDDSQHFAVKITK---FSNEEI-----------ILSETDTSNRLLKLS-----------------H
||...|||||  . | .||               ... .. |.|. |   . ...            .| |      | .|.                 |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKI---LKHLNKNHDPNWQRRDDPDNKHH

PNVCKAYDLFVEKS---------------FNTTYLIMEYINGQTIEQWIQQKQ---------TIEDNE------------IRFIM------NGLLEGID-
.|. | || |. |                ||  ||..||. ...  | |...|           .. .            |...|        .|.|.. 
NNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYM-DHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKL

-YLHQQG--FIHRDISSSNVIYDRDCKK-------------------VKIIDL-STCKDNKFSPH------------------RKLLT-VIGNDIYRAPE
 |.|...  .||||.  .|.  . .|.                    .||.|  . .. .. | |                  .. .|  .    |||||
KYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPE

MFEGA-----------YHQEVDIWAAGLILFQL-------LFQKHPFFE--SG-----------DDQVVLVQKVTQ------------------QE----
   |.           | ...|.|..| |.. .       .|...|.|   |.            ||  .  ||                    .|    
ILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPN

------------------------------------IDWDLLQKTNDK--------------------------------------VSPCQIDLCQEMLK
                                      |   .. ...                                       .|  ||| . ||.
MIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQ

KNPSDRISAKQALRHPFL
 .|..||.|.|||.||..
YDPDKRITAEQALQHPYF
Kinase 22504.AA STE 95-356 19 3.8e-39 135.9 In-house 1-359 (359) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-359/359
Sequence Identity: 19% (72 aa)

YEKLEKIGEGGNSCVHRCRRIN-----DDSQH---------FAVKITKFSN--------------------EEIILSETDTSNRLLKLSHPNVCKAYDLF
.|..||||.|.   |.......     .  .          .|.|. ...|                    .. || | .. ... .  |||. | |. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

V-----EKSFNTTYLIMEYINGQTIEQWIQQK--------------QTIEDNEIRFIMNGLLEG-IDYLHQQGFIHRDISSSNVIYDRDCKKVKIIDLST
.     .|. .. ...|||..| .... |..|              .... ..|..|   .|.|  .|||... ||||| ..|.        ||..|  .
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGV

CKDNKF---------------SPHRKLLTVIGNDIYRAPEMFEG-------AYHQEVDIWAAGLILFQLLFQKHPFFESGDDQV-VLVQ--KVTQQEIDW
|.                   .   |  |..|   . |||. ..        |   .|||  |. .  ..  |.|...  . ..  . .  .. ||  ..
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ--QF

DLLQKTND---------------------------KVSPCQIDLCQEMLKKNPSDRISAKQALR--HPFL
..| . ..                           |.||. .|  .  |.|.|..| .|.| |.  |||.
EQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 22504.AA ULK 95-356 24 1e-36 127.85 In-house 1-324 (324) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-324/324
Sequence Identity: 24% (79 aa)

YEKLEKIGEGGNSCVHRCRRINDDS----QHFAVKITK------FSNE-------EIILSETDTSNRLLKLSHPN--VCKAYDLFVEKSFNTTYLIMEYI
|.. ...|.|    |  .. .| ..    |..|.|.        ..||       . . .|  .   |  |.|||  ..| || | .. .| .|.|||| 
YCLNHCLGKGSFG-VKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYC

NGQTIEQWIQQKQT---------IEDNEIRFIMNGLLEGIDYLHQQGFIHRDISSSNVIYDRDCKK-----------VKIIDLSTCKDNKF--SPHRKLL
|| . || |.....         .. .|.. ..  ...|  .||... |||||  .|     .  |           .|| |   .|          .. 
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TVI------GNDIYRAPEMFEGA-----YH-QEVDIWAAGLILFQLLFQKHPFFESGDDQVV-----LVQK-------VTQQEIDWDLLQKTNDKVSPCQ
|        |  .| ||. ..|      |.  ..|||  | |....|. | |||..   . .     |...       . .| |....    ..|.||  
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPEC

IDLCQEMLKKNPSDRISAKQALRHPFL
.|| . ||.....||||  . . ||..
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 22504.AA ULK 95-356 22 1.5e-36 125.15 In-house 1-329 (329) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-329/329
Sequence Identity: 22% (75 aa)

YEKLEKIGEGGNSCVHRCRRINDD---SQHFAVKITK-------------------FSNEEIILSETD----TSNRLLKLSHPNVCKAYDLFVEKSFNTT
|.. ...|.|    |.. | ....    . .|.|.                     . ||  |. . .      |     .|||..| || | .. .| .
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKN-----HHPNIVKLYDWFETSNHNNI

YLIMEYINGQTIEQWIQQKQT----------IEDNEIRFIMNGLLEGIDYLHQQGFIHRDISSSNVIYDRDCKK-----------VKIIDLSTCKD-NKF
|.|||| || . || |.....          .. .|.. ..  .|.|  .||... |||||  .|.  . .  |           .|| |   .|  ...
YIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDND

-SPHRKLLTVI------GNDIYRAPEMFEGA-----YH-QEVDIWAAGLILFQLLFQKHPFFESGDDQVV------LVQK-------VTQQEIDWDLLQK
    . ..|        |  .| ||. ..|      |.  ..|||  | |....|. | ||...   . .      |...       . .| ....    
NMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDG-

TNDKVSPCQIDLCQEMLKKNPSDRISAKQALRHPFL
 ....||  .|| . ||.....||||  . . ||..
NDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 22504.AA CAMK-Unique 95-356 18 5.8e-36 116.06 In-house 1-363 (363) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-363/363
Sequence Identity: 18% (68 aa)

YEKLEKIGEGGNSCVHRCRRIN-DDSQHFAVKITKF-SNEEIILSE------------------TDTSNRLLK-LSHPNVCKAYDL----FVEKS-----
|.... ||.|. . | .|  ..      .|.|. |.   ..... .                  ..   ...| ..|||  | ||     |. .      
YKMHRIIGHGNFGHVYEC--MDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCD

--------FNTTYLIMEYINGQTIEQWIQQ--------------------KQTIED--NEIRFIMNGLLEGIDYLHQQGFIHRDISSSNVIYDRD-----
            |..|||..| .  .|||.                    ..  .   ....|||  ||. . |.|.|. .|||.   |. .        
LIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN

----------CKKVKIIDLSTCKDNKFSPHRK-LLTVIGNDIYRAP--------------EMFE-GAYHQEV----DIWAAGLILFQLLFQKHPFFESGD
          ....|..|   |..   .  .  . |..|  .| ||              |. .   | | .    |||. | |.. .|. ..|| ....
HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECE

DQ------VVLVQKVTQQEI-DWDLLQKTN-DKVSPCQIDLCQEMLKKNPSDRISAKQALRHPFL
|       . . .. .. .. . |  .    | .|.. .|. .  ..  |. |.|||..| |...
DRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 22504.AA CK2 95-306 28 2.9e-32 93.04 In-house 1-208 (288) Show / Hide 
Range on Protein: 95-306
Range on HMM: 1-208/288
Sequence Identity: 28% (62 aa)

YEKLEKIGEGGNSCVHRCRRINDDSQH-FAVKITKFSNEEIILSETDTSNRLLKLSHPNVCKAYDLFVEKSFNTTYLIMEYINGQTIEQWIQQKQTIEDN
||  .||| |  | |.  . |. . ..   .|| |    . |  |    . |   ..||. | ||  . ..  .. |. ||.|   . |     ||..| 
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLN--GGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLY---QTLTDY

EIRFIMNGLLEGIDYLHQQGFIHRDISSSNVIYDRDCKKVKIID--LSTCKDNKFSPHRKLLTVIGNDIYRAPEMF--EGAYHQEVDIWAAGLILFQLLF
.||. |  ||  .|| | .| .|||. ..|.. |   .| ..||  |.      . |  .    ..   |..||.      |   .|.|. | ......|
DIRYYMFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEF----YHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIF

QKHPFFESGDDQVVLVQ
.| |||.  | .  ||.
KKEPFFHGHDNYDQLVK
Kinase 22504.AA Ciliate-A9 95-219 24 2.9e-29 66.23 In-house 1-151 (392) Show / Hide 
Range on Protein: 95-219
Range on HMM: 1-151/392
Sequence Identity: 24% (38 aa)

YEKLEKIGEGGNSCVHRCRRIN-DDSQHFAVKITKFSNEEI--ILSETDTSNRLLKLSHPNVCKAYD---------------------LFVEKSFNTTYL
.|  ..||||   ||  || |. .| |  |||...  ...   |   .     |... |||. | .                       | | .  . . 
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKVIQKNKMKMDCIEFQDQEAKILQQHDHPNIVK-FKNIKNINTQKETKQLNYIFQISKFCESD-QNIHI

IMEYINGQTIEQWIQQKQTI----EDNEIRFIMNGLLEGIDYLHQQGFIHRDI
 |||. . |. | . ..        ..||. ||. .. ...|.||.. .|||.
VMEYMKCGTLQQLMKERKKNNQWFNEQEISQIMKCIMSAVMYMHQKNICHRDL
Kinase 22504.AA Ciliate-A9 260-356 25 1.7e-24 54.54 In-house 253-392 (392) Show / Hide 
Range on Protein: 260-356
Range on HMM: 253-392/392
Sequence Identity: 25% (37 aa)

IYRAPEMFEGA-YHQEVD-------------------------------------------IWAAGLILFQLL-FQKHPFFE---SGDDQVVLVQKVT--
|| ||| | .. | | ||                                           .|. | |...|| . |||| .   . ||.    .|    
IYMAPEFFINKQYSQPVDHAVSMKSRKRLIYLFLQLIILFLNSLKSQNQFILYRQFKQQVDMWSCGIIMYMLLCMGKHPFWCPYEKNDDEDYFKMKIQCN

QQEIDWDLLQKTNDKVSPCQIDLCQEMLKKNPSDRISAKQALRHPFL
.| . ||         |   ... |.|. .|||.| .| |.| ||. 
PQWEFWD-------NCSNNAKNFIQKMTNINPSNRYNAFQCLKHPWI
Kinase 22504.AA CK2 319-356 34 5.1e-09 22.28 In-house 251-288 (288) Show / Hide 
Range on Protein: 319-356
Range on HMM: 251-288/288
Sequence Identity: 34% (13 aa)

QKTNDKVSPCQIDLCQEMLKKNPSDRISAKQALRHPFL
| ... ..|  ||.   ||.  . .||.|| |. ||. 
QENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 22504.AA TyrKc 95-356 18 4.8e-08 -92.57 SMART 1-280 (280) Show / Hide 
Range on Protein: 95-356
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

YEKLEKIGEGGNSCVHRCRRINDDSQHFAVKITKFSNEEIILSETDTSNRLLKL--SHPNVCKAYDLFVEK-----SFNTTYLIMEYINGQTIEQWIQQK
 ....|.|||    |.... .    .  |||  | . .| ...|      . ||  .|||. . |   ...     .    ...|||  .    . .. .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARI---MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

QT-IEDNEIRFIMNGLLEGIDYLHQQGFIHRDISSSNVIYDRDCKKVKIIDLSTCKDNKFSPHR-------KLLTV----IGN--DIYR--APEMF-EGA
.  .   .   ..    .| .|||....||||.   |. ....   ||| |   ..| .   .        .  ..     |.    .|  ||| . .| 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIY---DDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YHQEVDIWAAGLILFQLL-FQKHPFFE---SGDDQVVLVQKVTQQEIDWDLLQKTNDKVSP-----CQIDLCQEMLK---KNPSDRISAKQALRHPFL
.  . |.|. |  .. .. . . |  .        ..  | | ..  . . . .  .   |     |  .. | |..    .|.|| . ..   | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----MMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF