Gene 13784 (Tetrahymena)

13784

Species: Tetrahymena
Alias: PreTt13784, 1140, TTHERM_00204110, 13784, 17.m00391
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: ERK

Sequence

Name Sequence Type Origin Length Description Download
13784.AA Protein None 269 None Fasta, JSON
13784.kin_dom Protein Kinase Domain None 159 None Fasta, JSON
13784.NA RNA None 810 None Fasta, JSON

Protein domain

Protein domains of 13784.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13784.AA Ciliate-E7 12-186 57 2.4e-121 409.41 In-house 114-290 (290) Show / Hide 
Range on Protein: 12-186
Range on HMM: 114-290/290
Sequence Identity: 57% (102 aa)

FLHSQNVYLYVMKRDSILLNQNCELKISDFLG--AKFPNDFDKKYINTNSYLSPYYILGLPEDFSKTDIWNVGVIILELFQIKNIFSDFCCSASGGLLTN
..|||..|   .    |..||||..|||||..  ..||....|||||.|.|.|||||....|.|||||||.||.|.|||.|....||||||....|..|.
YIHSQKIYHTQLTPRFIQINQNCDIKISDFIWCIGNFPHEINKKYINKNYYMSPYYIVEQMETFSKTDIWHVGCIFLELIQRYKFFSDFCCHDYNGVITQ

YFYYIGSPSKEDLDLLLEKGYKQQYNELLSLPFYRKQPWQVVFRRENPLLYDLLDKMLVFNEDKRYTVKECLQHPYF
|||..||...|||||...|.|..|||.|.....|.||.|||.|...||||.||||||||||||||..||||||||||
YFYFCGSQNEEDLDLKYYKQYNRQYNQLKMPKQYCKQSWQVQFPNANPLLCDLLDKMLVFNEDKRFNVKECLQHPYF
Kinase 13784.AA ERK 28-186 33 1.7e-32 114.28 In-house 139-307 (307) Show / Hide 
Range on Protein: 28-186
Range on HMM: 139-307/307
Sequence Identity: 33% (59 aa)

ILLNQNCELKISDFLGAKFPN-DFDKK----------YINTNSYLSPYYILGLPEDFSKTDIWNVGVIILELFQIKNIFSDFCCSASGGLLTNYFYYIGS
||.| || |||.|| .| ... ....           |. |  | .|  .| ...  ...||| .|.|. |..  | .|.      . . ..  | .||.
ILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLGRKPLFP---GKDYVHQINRIFQIIGT

P-SKEDLDLLLEKGYKQQYNELLSLPF--YRKQPWQVVFRREN--PLLYDLLDKMLVFNEDKRYTVKECLQHPYF
| |.|||    ...... .. . .||.  . ..||. .| . |  |.  |||.|||||..|||.||.|||.||||
PHSEEDLQ---YICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase 13784.AA MAPK 111-186 42 3.6e-23 76.8 In-house 248-328 (328) Show / Hide 
Range on Protein: 111-186
Range on HMM: 248-328/328
Sequence Identity: 42% (35 aa)

FYYIGSPSKEDLDLLLEKGYKQQYNELLSL---PFYRKQPWQVVFRR----ENPLLYDLLDKMLVFNEDKRYTVKECLQHPYF
. ..|.||.|..  . .  ..  .| . ||   | | |.||. .|       ||.  |||.|||||. |||.||.|.||||||
MEVLGTPSEEFIQCICM--SEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 13784.AA CMGC 28-186 17 3.5e-21 65.53 In-house 215-513 (513) Show / Hide 
Range on Protein: 28-186
Range on HMM: 215-513/513
Sequence Identity: 17% (54 aa)

ILLNQNCEL--------------------KISDFLGAK--FPNDFD----------------------KKYINTNSYLSPYYILGL---------PEDFS
||.|.||||                    || ||  |.   |.. .                        |. |  | .|  .||           .  .
ILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTT

KTDIWNVGVIILELFQI--------KNIFS----------------DFCCSASGGLLTNYFYYIGSP----------------SKEDLDLLL--------
. |.| || |. |...         | .|                 |         |   |  .|.|                ..|. . .         
PIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHID--------QLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFP

------------EKGYKQQYNELLSLPFYRKQPWQVVFRR-----------------------------------ENPLLYDLLDKMLVFNEDKRYTVKE
             ...... .  ...| ....||. .| .                                   ..|.. |||.|||... ||| |...
KKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQ

CLQHPYF
.||||||
ALQHPYF
Kinase 13784.AA ERK1 12-186 35 6.2e-20 71.39 In-house 115-289 (289) Show / Hide 
Range on Protein: 12-186
Range on HMM: 115-289/289
Sequence Identity: 35% (65 aa)

FLHSQNVYLYVMKRDSILLNQNCELKISDFLGAKF--PND----FDKKYINTNSYLSPYYILGLPEDFSKTDIWNVGVIILELFQIKNIFSDFCCSASGG
..|| ||    .|   .|||. |.||| ||  |.   |.     |   |. |  |  |  .|         ||| || |. |.   . ||          
YIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLD---

LLTNYFYYIGSPSKEDLDLLLEKGYKQQYNELLSLPFYRKQPWQVVFRRENPLLYDLLDKMLVFNEDKRYTVKECLQHPYF
 |      .||||..||. ..    ..  | | |||.  |.||. .| .  .   ||||||| || .|| || | | ||| 
QLNHILGVLGSPSQDDLNCIIN---EKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase 13784.AA p38 139-186 45 1.2e-15 49.72 In-house 242-289 (289) Show / Hide 
Range on Protein: 139-186
Range on HMM: 242-289/289
Sequence Identity: 45% (22 aa)

SLPFYRKQPWQVVFRRENPLLYDLLDKMLVFNEDKRYTVKECLQHPYF
|.| . ..  . ||.. ||.  |||.|||.  .||| |..| .|||||
SYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase 13784.AA CDK 139-186 35 4.5e-13 38.0 In-house 254-284 (284) Show / Hide 
Range on Protein: 139-186
Range on HMM: 254-284/284
Sequence Identity: 35% (17 aa)

SLPFYRKQPWQVVFRRENPLLYDLLDKMLVFNEDKRYTVKECLQHPYF
.|| |                 |||.|||... .|| . ...||||||
KLPDY-----------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 13784.AA CRK7 161-186 61 8e-13 40.35 In-house 318-343 (343) Show / Hide 
Range on Protein: 161-186
Range on HMM: 318-343/343
Sequence Identity: 61% (16 aa)

DLLDKMLVFNEDKRYTVKECLQHPYF
|||||||. . .|| |..|||||..|
DLLDKMLCLDPKKRFTAEECLQHDWF
Kinase 13784.AA Ciliate-C4 158-186 48 4e-12 34.79 In-house 333-361 (361) Show / Hide 
Range on Protein: 158-186
Range on HMM: 333-361/361
Sequence Identity: 48% (14 aa)

LLYDLLDKMLVFNEDKRYTVKECLQHPYF
.|.||..|||.||. .| . |.|.|||..
QLKDLIKKMLKFNPRERISPKQCCQHPWI
Kinase 13784.AA nmo 161-186 50 3.7e-10 26.81 In-house 267-292 (292) Show / Hide 
Range on Protein: 161-186
Range on HMM: 267-292/292
Sequence Identity: 50% (13 aa)

DLLDKMLVFNEDKRYTVKECLQHPYF
.|| .||.|. |||  .|. |.||| 
HLLCRMLHFDPDKRISCKDALAHPYL
Kinase 13784.AA Pkinase 149-186 26 1.5e-08 31.33 Pfam 257-293 (293) Show / Hide 
Range on Protein: 149-186
Range on HMM: 257-293/293
Sequence Identity: 26% (10 aa)

QVVFRRENPLLYDLLDKMLVFNEDKRYTVKECLQHPYF
...  . .. . |.....| ..  ||.| ...||||.|
WTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 13784.AA nmo 12-95 34 7e-06 13.35 In-house 117-204 (292) Show / Hide 
Range on Protein: 12-95
Range on HMM: 117-204/292
Sequence Identity: 34% (30 aa)

FLHSQNVYLYVMKRDSILLNQNCELKISDFLGAKFPNDFDKKYIN----TNSYLSPYYILGLPEDFSKTDIWNVGVIILELFQIKNIF
.||| |.    .|   .|.| || ||| ||  |.  .  ..| .     |  |  |  ..|     |  ||| || |  || . . .|
YLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELLGRRILF
S_TKc 13784.AA S_TKc 2-186 13 4.1e-05 -102.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 2-186
Range on HMM: 1-231/231
Sequence Identity: 13% (39 aa)

Y-----------------------------------------------YLLNIKSSFF---------LHSQ---NVYLYVMKRDS---------------
|                                               .. ... .|          . ..   ... |  || .               
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

------------------------ILLNQNCELKISDF-LGAKFPNDFDKKYINTNSYLSPYYILGLPEDFS--KTDIWNVGVIILELFQIKNIFSDFCC
                        |||..  ..||.|| | ...     . .. |  |..|  .      ..  | |.| .|.|. |..  .  |.    
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP----

SASGGLLTNYFYYIGSPSKEDLDLLLEKGYKQQYNELLSLPFYRKQPWQVVFRRENPLLYDLLDKMLVFNEDKRYTVKECLQ-------HPYF
      .   |  ||                                         | . |...|.|... .||.|. |.||       ||.|
-----QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13784.AA MAPK 28-41 71 0.000152 11.38 In-house 148-161 (328) Show / Hide 
Range on Protein: 28-41
Range on HMM: 148-161/328
Sequence Identity: 71% (10 aa)

ILLNQNCELKISDF
||.|.||.||| ||
ILVNENCDLKICDF
Kinase 13784.AA Ciliate-C4 77-89 38 0.006128 4.87 In-house 254-266 (361) Show / Hide 
Range on Protein: 77-89
Range on HMM: 254-266/361
Sequence Identity: 38% (5 aa)

DIWNVGVIILELF
|||..|....|..
DIWSMGCVMMEII
Kinase 13784.AA CRK7 77-95 52 0.083382 1.77 In-house 235-253 (343) Show / Hide 
Range on Protein: 77-95
Range on HMM: 235-253/343
Sequence Identity: 52% (10 aa)

DIWNVGVIILELFQIKNIF
|.| .| |  |||  |.||
DMWSCGCILGELFTKKPIF
Kinase 13784.AA CDK 77-95 40 0.09204 1.23 In-house 204-225 (284) Show / Hide 
Range on Protein: 77-95
Range on HMM: 204-225/284
Sequence Identity: 40% (9 aa)

DIWNVGVIILELFQ---IKNIF
|.| || |. |.|.    | .|
DMWSVGCIFAEMFTDVTRKPLF
Kinase 13784.AA p38 30-95 34 0.176471 0.49 In-house 139-204 (289) Show / Hide 
Range on Protein: 30-95
Range on HMM: 139-204/289
Sequence Identity: 34% (23 aa)

LNQNCELKISDFLGAKFPNDFDKKYINTNSYLSPYYILGLPEDFSKTDIWNVGVIILELFQIKNIF
.| .|||.| ||  |    |    |. |  |..|  .|   .   . ||| || |. || . .  |
VNEDCELRILDFGLARHCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMAELITGRTLF
Kinase 13784.AA Pkinase 28-41 38 5.507682 1.03 Pfam 139-156 (293) Show / Hide 
Range on Protein: 28-41
Range on HMM: 139-156/293
Sequence Identity: 38% (7 aa)

ILLNQNCEL----KISDF
||...|...    ||.||
ILIDNNGHIDACVKICDF