Gene AqueK129 (A.queenslandica)

AqueK129

Species: A.queenslandica
Alias: AqueK129
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: p38

Sequence

Name Sequence Type Origin Length Description Download
AqueK129.AA Protein None 361 None Fasta, JSON
AqueK129.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of AqueK129.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK129.AA p38 28-313 68 7e-208 696.9 In-house 1-289 (289) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-289/289
Sequence Identity: 68% (198 aa)

YREIASIGTGAYGTVCSATDTHYNIK---VALKKLARPFQNHVHAKRTYRELRLLKHMKHENIIGLLDVFTP-AENYENFQDVYLVMHLMGSDINNILKQ
|...  .|.||||.||.| |.  . |   || |||.||||  .|||||||||||||||.|||.|.||||||| |.. ..|||||.|.|.||.| |||.|.
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRHENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMKC

QALTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARATDQEMTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGCIMAELLT
|.|.|.|.|||||||||||||.|||||.||||||||||||||||||||||||||..|.|||||||||  |||||||||||| .   |.||||||||||.|
QRLSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLARHCDDEMTGYVATRWYRAPEIMLNWMHYTQT-VDIWSVGCIMAELIT

GQVLFPGSDHIDQLTKILQIVGTPDQEFVTKITSDTARSYIESLPKYPKKDFHTFFQGANPLAIDLLQMLLTIDPDKRITAEQALLHPYM
|..||||.||||||..|....||||.||..|| |. ||.||.|.|..|..|||. |.||||.||||| ..| .|||||||||.|. |||.
GRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase AqueK129.AA MAPK 28-313 53 3.1e-192 644.92 In-house 1-328 (328) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-328/328
Sequence Identity: 53% (177 aa)

YREIASIGTGAYGTVCSATDTH------YNIKVALKKLARPFQNHVHAKRTYRELRLLKHM-KHENIIGLLDVFTP-----AENYENFQDVYLVMHLMGS
|. .  || ||||.||||.|.       .. |||.||. |||||..|.||||||..||.|. .|||||.|||.|||     ... |.|.|.|.||.||..
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DINNILK-QQALTDEHVQFLVYQILRG--LKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARATDQE-----------------MTGYVATRYWRAP
| ..|.| || |.|.|.|...||||||  ||| |||...|||||||||.|||.|.|.|.|||||| .|.|                 ||.|||||. |||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

EIMLN--WMHYGKEGFDMWSVGCIMAELLT-GQVLFPGSDHIDQLTKILQIVGTPDQEFVTKIT-SDTARSYIESL---PKYPKKDFHTFFQG----ANP
|||||  |||| ... ||||||||.||.|| ...||||.|.|||...|....|||..||. .|. |. ||.||.||   ||||||.... | .    |||
EIMLNWIWMHY-TKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANP

LAIDLLQMLLTIDPDKRITAEQALLHPYM
.|||||. .|..|||||||.|.|| |||.
QAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase AqueK129.AA ERK 28-313 49 6.2e-148 497.76 In-house 1-307 (307) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-307/307
Sequence Identity: 49% (153 aa)

YREIASIGTGAYGTVCSATDTH-----YNIKVALKKLARPFQNHVHAKRTYRELRLLKHMK-HENIIGLLDVFTPAENYENFQDVYLVMHLMGSDINNIL
|. |  || ||||.||||.|.       . ||| ||  ..| . . .|||.||..||.| | |||||.|.|.. |     .. |.|.|  || .|   | 
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII

K-QQALTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLAR---ATDQE--------MTGYVATRYWRAPEIMLNWMHYGKEGF
. ||.|.|.|.|...||||.||||.|||...||||||||| ||..| | | ||||||   |. ||        ||.|||||. |||||||.|  | |.  
NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKA-M

DMWSVGCIMAELLTGQVLFPGSDHIDQLTKILQIVGTP-DQEFVTKITSDTARSYIESLPK--YPKKDFHTFFQGAN--PLAIDLLQMLLTIDPDKRITA
|.||.|||.||.| .. |||| |...|.. |.|| ||| ..| . .|.|. |. || .||.  .|.|.. . |  ||  |.|||||. .|..|||||||.
DIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITV

EQALLHPYM
|..| ||| 
EECLEHPYF
Kinase AqueK129.AA CMGC 28-313 28 8.8e-139 459.15 In-house 1-513 (513) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-513/513
Sequence Identity: 28% (145 aa)

YREIASIGTGAYGTVCSATDTH--------------YNIKVALKKLARPFQNHVHAK----------RTYRELRLLKHMK-----------------HEN
|  |  || |.||.|....|..              .| .||.||. .|| .. .||          |..||...|||..                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IIGLLDVFTPAENYEN-----------FQDVYLVMHLMGSDINNILKQQA----------LTDEH------------VQFLV------YQILRGLK--YV
|..|.|.|.. ..  |           |...|||. .|. |  ...|..           |.. |            .....      ||||||||  | 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HSAG--IVHRDLKPSNIAVNEDCEL--------------------RILDFGLARATDQE------------------------MTGYVATRYWRAPEIML
||..  |.||||||.|| .|..|||                    .| ||||||.....                        .| ||.||. |||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

NWMHYG--------KEGFDMWSVGCIMAELLTG--------QVLFP-----------GSDHIDQLTKILQIVGTP----------------DQEFVTKIT
.| ||          .. ||||||||.||..||        . |||           |..||||| || .. |||                ..|. ..| 
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

--------------------SDTARSYIES---LPKYPKKDFHTFFQG-----------------------------------ANPLAIDLLQMLLTIDP
                    |. || ||.|   .|..|.|... .| .                                   ..|.|||||. .|..||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

DKRITAEQALLHPYM
|||||||||| ||| 
DKRITAEQALQHPYF
Kinase AqueK129.AA JNK 28-313 45 3.5e-125 422.16 In-house 1-309 (309) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-309/309
Sequence Identity: 45% (142 aa)

YREIASIGTGAYGTVCSATDTHYNIKVALKKLARP--FQNHVHAKRTYRELRLLKHMKHENIIGLLDVFTPAENYENFQDVYLVMHLMGSDINNILKQ--
|    .|| || |.||.| |.  | .|| ||. ||  |||  |.|| |||. ..|. .|.|||... .|||.|. | |||||.|| .|     ..     
YQNLKFIGQGAQGIVCMAFDQVTNQRVAIKKMMRPDNFQNWMHWKRAYREFICMKCINHKNIIKMYNCFTPQETLEEFQDVYIVMEYMDWNLCQVIHSTF

QALTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARATDQE--MTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGCIMAEL
  |  | . .|.||...| |. ||.|| ||||||||| ||.|| | |.|||.||  |    || || ||| ||||. .  |   ||  | |||||||||.
MELDHERMSYLFYQMCCGIKHLHSMGIIHRDLKPSNIVVNQDCTLKICDFGHARTEDPTFMMTPYVVTRYYRAPEVICGMMDNYKENVDIWSVGCIMAEM

LTGQVLFPGSDHIDQLTKILQIVGTPDQEFVTKITSDTARSYIESL---PKYPKKDFH-----TFFQG---ANPL-------AIDLLQMLLTIDPDKRIT
....|||||.||||| .|| .  ||||..|  .   ...| |.|..   |.|.   ||     | |..   ..|        | |||   | |.||.|| 
IRHHVLFPGKDHIDQWNKIIEFLGTPDPHFMMQMQ-PHVRNYVENRNMDPYYQPYNFHEHFPDTLFPDVMQSEPKDHLTCHMARDLLFRMLVINPDDRIS

AEQALLHPYM
 ..|| ||| 
VDDALQHPYI
Kinase AqueK129.AA ERK1 28-313 48 1.4e-110 373.7 In-house 1-289 (289) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-289/289
Sequence Identity: 48% (142 aa)

YREIASIGTGAYGTVCSATDTHYNIKVALKKLARPFQNHVHAKRTYRELRLLKHMKHENIIGLLDVFTPAENYENFQDVYLVMHLMGSDINNILKQQALT
| ... || |||| |||| ||  . .||.||.. ||    . .|| ||...|.  ||||||.. |.   |.  |...|||.|  ||  |.  .|| | | 
YTNLQYIGEGAYGMVCSAYDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFKHENIINIQDIIR-ADTIEQMRDVYIVQCLMETDLYKLLKTQHLS

DEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARATDQE------MTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGCIMAEL
 .|. . .|||||||||.||| ..||||||||. .|  |.|.| |||||| .| |      .| |||||..||||||||   | |   |.||||||.||.
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKS-IDIWSVGCILAEM

LTGQVLFPGSDHIDQLTKILQIVGTPDQEFVTKITSDTARSYIESLPKYPKKDFHTFFQGANPLAIDLLQMLLTIDPDKRITAEQALLHPYM
|    .|||   .||| .|| ..| | |. .  |  . ||.|..|||  ||  ..  | .| . |.|||. .||  |.|||| |.|| |||.
LSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL
Kinase AqueK129.AA ERK5 28-313 43 2.7e-106 359.45 In-house 1-295 (295) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-295/295
Sequence Identity: 43% (128 aa)

YREIASIGTGAYGTVCSATDTHYNIKVALKKLARPFQNHVHAKRTYRELRLLKHMKHENIIGLLDVFTPAENYENFQDVYLVMHLMGSDINNILK-QQAL
|. |  ||.|||| ||||       .||.||.   |     ||||.|||..|.| .|.||| . |.  | . |  ..||| |. || ||.  |.  .| .
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRHDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQPF

TDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLAR-----ATDQE---MTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGCIM
| ||. . .|||||||||.||| ..||||||||. ||| |||.| |||.||     ..|..   || |||||..||||.|.    | .   |.||||||.
TLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQ-AIDVWSVGCIF

AELLTGQVLFPGSDHIDQLTKILQIVGTPDQEFVTKITSDTARSYIES-LPKYPKKDFHTFFQGANPLAIDLLQMLLTIDPDKRITAEQALLHPYM
 |... . .|||   |.||  |....|.|    .  . .|  . |. . .|    ||. . . .| . |.|||  .|  .| .|||. .|| ||..
GEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL
Kinase AqueK129.AA ERK7 28-313 42 1e-104 354.16 In-house 1-292 (292) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-292/292
Sequence Identity: 42% (125 aa)

YREIASIGTGAYGTVCSATDTHYNIKVALKKLARPFQNHVHAKRTYRELRLLKHMK-HENIIGLLDVFTPAENYENFQDVYLVMHLMGSDINNILK-QQA
|  .  .| |||| |  |.|      |||||    |.|.. | ||.||  .|. .. |.||| |..|. .|.|    .|.|||   | .|.... .  . 
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVI-RADND---RDIYLVFEFMETDLHAVIRKGNI

LTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARA-TDQE--------MTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGC
| | |.|. .||.|| .||.||. ..||||||||| .. .| ... ||||||  ..||        .| ||||| .|||||.|   .| | | ||||.||
LKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTK-GVDMWSIGC

IMAELLTGQVLFPGSDHIDQLTKILQIVGTPDQEFVTKITSDTARSYIESLPKYPKKDFHTFFQGANPLAIDLLQMLLTIDPDKRITAEQALLHPYM
|..|.|.|. .|||.  ..|. |||.... | || .  | |. | . .|.... ..| .. ..... . |||||. ||   |.||.|||||| ||| 
ILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase AqueK129.AA nmo 29-313 43 4.7e-94 289.61 In-house 2-292 (292) Show / Hide 
Range on Protein: 29-313
Range on HMM: 2-292/292
Sequence Identity: 43% (127 aa)

REIASIGTGAYGTVCSATDTHYNIKVALKKLARPFQNHVHAKRTYRELRLLKHMKHENIIGLLDVFTPAENYENFQDVYLVMHLMGSDINNIL-KQQALT
.    || ||.| | | ||     .|||||.   ||| | .|| .|||..|   ||.|.. .||.  |. . . ||..| |  || ||.  |.   |.|.
QPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPP-HKDFFQEIYVVTELMQSDLHKIIVSPQHLS

DEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARATDQE----MTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGCIMAELLT
 .||.  .|||||||||.|||.|.|||.|| |. || .| |.| ||||||  .|.    ||  | | |.|||||..   ||  .  |.|||||| |||| 
SDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHY-TSAVDIWSVGCIFAELLG

GQVLFPGSDHIDQLTKILQIVGTPDQEFVTKITSDTARSYI-ESLPKYPKKDFHTFFQG---ANPLAIDLLQMLLTIDPDKRITAEQALLHPYM
 ..||     |.||  | ...||| .| . |   . |.. .    .| |. .          |.  |..||. .|  |||||| ...|| |||.
RRILFQAQSPIQQLQMITDLLGTPSMEDM-KYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL
Kinase AqueK129.AA S_TKc 28-313 29 4.4e-88 299.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-231/231
Sequence Identity: 29% (88 aa)

YREIASIGTGAYGTVCSATDTHYNIKVALKKLARPFQNHVHAKRTYRELRLLKHMKHENIIGLLDVFTPAENYENFQDVYLVMHLMGS---DINNILKQQ
|. .  || ||.|.|. ..... . .||.|..          ....||...||. .|.||. |.|||         ...|.|| ...    |   ..|..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKR

A-------LTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARATDQEMTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGCI
        ..  |..|..|||...|.| || ||.||||||.|| ..|  .. | ||||||      | .. |....|||..    .|||.  |.||.|||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

MAELLTGQVLFPGSDHIDQLTKILQIVGTPDQEFVTKITSDTARSYIESLPKYPKKDFHTFFQGANPLAIDLLQMLLTIDPDKRITAEQALL-------H
..|.|.|. .||      |. ......|                                      | |.|... .|. ||.||.|| .||        |
LYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCH

PYM
|..
PWF
Kinase AqueK129.AA Pkinase 28-313 30 1.4e-83 288.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-293/293
Sequence Identity: 30% (93 aa)

YREIASIGTGAYGTVCSATDTHYNIKVALKKLARPFQNHVHAKRTYR--ELRLLKHMKHENIIGLLDVFTPAENYENFQDVYLVMHLM-GS----DINNI
|. .  || |..|.|. ...  ....||.|.. .. ...   ..  |  |....|...|.||. |.|.|.        ...|.|| .. |     |   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY

LK---QQAL--TDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCEL----RILDFGLA----RATDQEMTGYVATRYWRAPEIMLNWMHYGKE
..   . ..  ......| .|||||||.| || ||.||||||.|| .......    .| |||||       .. ||... |....|||. .   .||..
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

GFDMWSVGCIMAELLTGQVLFPGS----DHIDQLTKILQIVGTPDQEFVTKITSDTARSYIESLPKYPKKDFHTFFQGANPLAIDLLQMLLTIDPDKRIT
  ||||.|||..|.|.|. .|||.    . .||. .| .| |.|  .   .  |   .. .   .    . . ||   ... ..|..  .|. || ||.|
V-DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPT

AEQALLHPYM
|||.| ||..
AEQILQHPWF
Kinase AqueK129.AA MAPK-Unclassified 28-177 46 8.5e-70 238.2 In-house 1-157 (575) Show / Hide 
Range on Protein: 28-177
Range on HMM: 1-157/575
Sequence Identity: 46% (74 aa)

YREIASIGTGAYGTVCSATDTHY-NIKVALKKLARPFQNHVHAKRTYRELRLLKHMKHENIIGLLDVFTPAENYEN--FQDVYLVMHLMGS---DINNIL
|  .  || |||| || |.|.   | .|| ||... |.||. .||. ||.|.| .. |.||| . |.|.. |  .|  |.|.|.|| .| .   |.  |.
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNHPNIIQIQDIFYNKEL-HNQEFDDIYIVMDYMQTSLFDLHQII

KQQA--LTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLAR
|.    . ..|.| . ||||||||| |||.|.||||||||. .|.|| .|| |||..|
KSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR
Kinase AqueK129.AA MAPK-Unclassified 179-313 34 1.1e-47 164.74 In-house 401-575 (575) Show / Hide 
Range on Protein: 179-313
Range on HMM: 401-575/575
Sequence Identity: 34% (60 aa)

TDQEMTGYVATRYWRAPEIMLNWMHYGKEGFDMWSVGCIMAELLTG-----------QVLFPGSD--------------------HIDQLTKILQIVGTP
.  .||.||.||. |||||||    |..   |.||.||| ||..             . ||||.|                    |.||.  |.   |.|
HCYHMTQYVVTRWYRAPEIMLSMHEYDTQ-VDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMP

DQEFVTKITSDTARSYIESLPKYPKKDFHTFFQGANP----------LAIDLLQMLLTIDPDKRITAEQALLHPYM
..|    ||.| || ||.|. . .  .|  ..  ..|          ..||..| .| ..| |||||.|||.|||.
PEEDCNFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase AqueK129.AA TyrKc 28-313 21 3e-13 -8.54 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-313
Range on HMM: 1-280/280
Sequence Identity: 21% (70 aa)

YREIASIGTGAYGTVCSATDTHYNIKVALKKLARPFQNHVHAKRTYRELRLLKHM--KHENIIGLLDVFTPA-ENYENF---QDVYLVMHLMGS-DINNI
 . .  .| ||.|.|. .| .   |.|| |.|          .  .||.|....   .|.||. |. | |   .|   |   . ...|| .|   | .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---FMYIEPLMIVMEYMPHGDLKDY

LKQQA--LTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARATDQE-------MTGYV----ATR-----YWRAPEIMLNWM
|.     |. ..     .|| .|  | || ...||||   |. |.|.   .| ||||.|. . .        .  .     ..      | ||| . |  
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

HYGKEGFDMWSVGCIMAELLT-GQVLFPGS----DHIDQLTKILQIVGTPDQEFV----TKITSDTARSYIESLPKYPKKDFHTFFQGANPLAIDLLQML
 .  .  | || |  | |..| ||   ||        ... . ..  . ..|                                |  .. .   .. .. 
KFTTKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------F-VCCPDEMYQIMKQC

LTIDPDKRITAEQALLHPYM
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WHEDPEDRPTFSEI--HECF
Kinase AqueK129.AA Pkinase_Tyr 28-178 30 5e-06 21.03 Pfam 1-160 (270) Show / Hide 
Range on Protein: 28-178
Range on HMM: 1-160/270
Sequence Identity: 30% (50 aa)

YREIASIGTGAYGTVCSATDT----HYNIKVALKKLARPFQNHVH--AKRTYRELRLLKHM-KHENIIGLLDVFT-PAE-NYENFQDVYLVMHLMGS-DI
 . .  .| ||.|.|. .| .      .|.|| |.| ..   | .   .   ||....|.. .|.||. |. | |   | |      .|.|| .|   | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-----QIYIVMEYMPHGDL

NNILKQQ-----ALTDEHVQFLVYQILRGLKYVHSAGIVHRDLKPSNIAVNEDCELRILDFGLARA
 . |...     .|| ..     .|| .|. | .| ...||||   |. |.|.   .| ||||||.
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD