Gene CDK-Un_c (S.moellendorffii)

CDK-Un_c

Species: S.moellendorffii
Alias: CDK-Un_c
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
CDK-Un_c.AA Protein None 602 None Fasta, JSON
CDK-Un_c.NA RNA None 1809 None Fasta, JSON
CDK-Un_c.kin_dom Protein Kinase Domain None 197 None Fasta, JSON

Protein domain

Protein domains of CDK-Un_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc CDK-Un_c.AA S_TKc 148-487 14 1.1e-13 24.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 148-487
Range on HMM: 1-231/231
Sequence Identity: 14% (52 aa)

FVLEKKIGEGAFGSVYKGSFANPQKKVLGFLVVKKASEYGEVEAWMNQRVRRACPGKCADYLDGFKMRVNPKRKEFWLVWRYEGVATLADFMSSKDFPYN
. . .|||.||||.|||.   .          .|. .                                                               
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK------------------------------------------------------------EHI

VSEFSVHARMDLLKISNRDRQVE-----------KA--LSLKTTLLAKGAE-----RENQIIQSLLQELLKCLRGLHDTGIVHRDIKPQNIIFSDESKSF
 .| ... . .   | .     .                .|.. .  .| .          .......... |  .|. ||.|||.||.|| ...     
RREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HI

KIIDLGAATDLRVGINYIPQEFLLDPRYAAPEQYIMSTQTPSAPSPVIATALSPVLWQLNLPD-RFDIYSLGLMFLQMVF-SNLRSDSALIQFNRQLKRM
||.| | |. |          |   | | |||                                . |..|.| ..  |.    . .     | .. .|..
KICDFGLARQL--------TTFCGTPWYMAPEVL-------------------------GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKI

DHDLVAWRDLVDARPNADVQRGFEILDMDGGAGWELLQAMMQFKGRQRISAKAALG-------HPYF
                                ...... ..|.  ..|..|  ||        ||.|
G----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CDK-Un_c.AA Ciliate-E2-Unclassified 287-411 23 3.1e-13 42.28 In-house 136-268 (352) Show / Hide 
Range on Protein: 287-411
Range on HMM: 136-268/352
Sequence Identity: 23% (36 aa)

ENQIIQ-----SLLQELLKCLRGLHDTG-IVHRDIKPQNIIFSDESK--SFKIIDLGAATDLRVGINY-----------IPQEF---LLDPRYA----AP
. | ..      .. ..|..|  ||  . |.||||||.||.|... |    ||||.| .  .   .|.           ..|..      |.|     ||
TEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAP

EQYIM-STQTPSAPSPVIATALSPVLWQLNLPDRFDIYSLGLMFLQMVFSNL
| .      ...|                      ||.|||  . .|.| ..
EVLQGQNYDHSKA-------------------YKCDIWSLGVILYEMLFGYY
Kinase CDK-Un_c.AA Ciliate-E2a 291-347 36 3.1e-13 35.34 In-house 103-167 (275) Show / Hide 
Range on Protein: 291-347
Range on HMM: 103-167/275
Sequence Identity: 36% (24 aa)

IQSLLQELL-KCLRGLHDTGIVHRDIKPQNIIFS---DES---KSFKIIDLGAATDLRVGIN-YI
| ...| || . |  .|  .|.|||.||.||.|     .|   .  |||| | ||.    .. |.
ICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYM
Kinase CDK-Un_c.AA CK2 291-337 44 1.3e-12 33.19 In-house 97-143 (288) Show / Hide 
Range on Protein: 291-337
Range on HMM: 97-143/288
Sequence Identity: 44% (21 aa)

IQSLLQELLKCLRGLHDTGIVHRDIKPQNIIFSDESKSFKIIDLGAA
|.  . |||| |   |  ||.|||.||.||.   | .  ..|| | |
IRYYMFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLA
Kinase CDK-Un_c.AA CMGC 289-335 21 2.3e-12 36.02 In-house 174-249 (513) Show / Hide 
Range on Protein: 289-335
Range on HMM: 174-249/513
Sequence Identity: 21% (16 aa)

QIIQSLL------QELLKCLR--GLHDTG--IVHRDIKPQNIIFSDESKSF-------------------KIIDLG
. |....      . .|..|    .|  .  |.|||.||.|| .... ...                   ||.| |
HNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG
Kinase CDK-Un_c.AA Ciliate-E2 289-340 29 3.5e-12 38.09 In-house 145-206 (365) Show / Hide 
Range on Protein: 289-340
Range on HMM: 145-206/365
Sequence Identity: 29% (20 aa)

QIIQSLLQELLK---------------CLRGLHDTG-IVHRDIKPQNIIFSDESKSFKIIDLGAATDL
. |. . ...|.               .|. ||  . |.||||||.||.|       ||||.| ....
KEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGLSKKY
Kinase CDK-Un_c.AA CDK5 458-487 63 1.8e-11 32.04 In-house 258-287 (287) Show / Hide 
Range on Protein: 458-487
Range on HMM: 258-287/287
Sequence Identity: 63% (19 aa)

GAGWELLQAMMQFKGRQRISAKAALGHPYF
. | .||| |.|..  ||||||||| ||||
EKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase CDK-Un_c.AA ULK 289-340 30 2.4e-10 32.42 In-house 130-192 (329) Show / Hide 
Range on Protein: 289-340
Range on HMM: 130-192/329
Sequence Identity: 30% (19 aa)

QIIQSLLQELLKCLRGLHDTGIVHRDIKPQNIIFSDESKS-----------FKIIDLGAATDL
|.... .. .|  .. ||. .|.|||||||||  ..   .           .|| | | |  .
QEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHV
Kinase CDK-Un_c.AA ULK 289-340 28 2.5e-10 32.89 In-house 126-188 (324) Show / Hide 
Range on Protein: 289-340
Range on HMM: 126-188/324
Sequence Identity: 28% (18 aa)

QIIQSLLQELLKCLRGLHDTGIVHRDIKPQNIIFSDESKS-----------FKIIDLGAATDL
|.... .. ..  .. ||. .|.|||||||||  ..   .           .|| | | |  .
QEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHV
Kinase CDK-Un_c.AA CDC2 460-487 57 4.3e-10 26.66 In-house 274-301 (301) Show / Hide 
Range on Protein: 460-487
Range on HMM: 274-301/301
Sequence Identity: 57% (16 aa)

GWELLQAMMQFKGRQRISAKAALGHPYF
| .||. | |    .|||||.|| ||||
GIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CDK-Un_c.AA Pkinase 305-408 24 7e-10 36.02 Pfam 124-207 (293) Show / Hide 
Range on Protein: 305-408
Range on HMM: 124-207/293
Sequence Identity: 24% (26 aa)

LHDTGIVHRDIKPQNIIFSDESKSF----KIIDLGAATDLRVGINYIPQEFLLDPRYAAPEQYIMSTQTPSAPSPVIATALSPVLWQLNLPDRFDIYSLG
.|. ||.|||.||.|| .. .        ||.| | |  ..   |  .. |   |.|.|||                         .   . . |..|.|
CHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---------------------GGQYYGPKVDMWSCG

LMFLQMVF
... .|..
CILYEMLC
Kinase CDK-Un_c.AA CDK 462-487 50 1.1e-09 26.94 In-house 259-284 (284) Show / Hide 
Range on Protein: 462-487
Range on HMM: 259-284/284
Sequence Identity: 50% (13 aa)

ELLQAMMQFKGRQRISAKAALGHPYF
.||. |...   .||||..|| ||||
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CDK-Un_c.AA CMGC 462-487 50 6.6e-09 24.43 In-house 488-513 (513) Show / Hide 
Range on Protein: 462-487
Range on HMM: 488-513/513
Sequence Identity: 50% (13 aa)

ELLQAMMQFKGRQRISAKAALGHPYF
.||. |.|.   .||.|. || ||||
DLLKKMLQYDPDKRITAEQALQHPYF
Kinase CDK-Un_c.AA CDK 291-335 36 9.5e-09 23.94 In-house 110-158 (284) Show / Hide 
Range on Protein: 291-335
Range on HMM: 110-158/284
Sequence Identity: 36% (18 aa)

IQSLLQELLKCLRGLHDTGIVHRDIKPQNIIFSDESK----SFKIIDLG
|..... ||. |  .|. .|.|||.|||||  ..  .    . || | |
IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFG
Kinase CDK-Un_c.AA CDC2 289-335 36 1.6e-08 21.73 In-house 103-148 (301) Show / Hide 
Range on Protein: 289-335
Range on HMM: 103-148/301
Sequence Identity: 36% (17 aa)

QIIQSLLQELLKCLRGLHDTGIVHRDIKPQNIIFSDESKSFKIIDLG
|...|..  .|. .  .|  .|.|||.|||||  ... .  || | |
QLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFG
Kinase CDK-Un_c.AA CK2 463-487 44 2.9e-08 19.96 In-house 264-288 (288) Show / Hide 
Range on Protein: 463-487
Range on HMM: 264-288/288
Sequence Identity: 44% (11 aa)

LLQAMMQFKGRQRISAKAALGHPYF
.|  |...   .||.|| |..||||
FLDKMLRYDHQERITAKEAMEHPYF
Kinase CDK-Un_c.AA CDK5 287-319 45 8.3e-07 17.02 In-house 96-128 (287) Show / Hide 
Range on Protein: 287-319
Range on HMM: 96-128/287
Sequence Identity: 45% (15 aa)

ENQIIQSLLQELLKCLRGLHDTGIVHRDIKPQN
. .||.|..  ||| |   |.  . ||| ||||
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQN
Kinase CDK-Un_c.AA ULK 148-165 50 1e-06 19.21 In-house 1-18 (329) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-18/329
Sequence Identity: 50% (9 aa)

FVLEKKIGEGAFGSVYKG
..| ...|.|.|| ||||
YCLNHCLGKGSFGKVYKG
Kinase CDK-Un_c.AA ULK 148-165 47 2e-06 19.3 In-house 1-19 (324) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-19/324
Sequence Identity: 47% (9 aa)

FVLEKKIGEGAFG-SVYKG
..| ...|.|.||  ||||
YCLNHCLGKGSFGVKVYKG
Kinase CDK-Un_c.AA Ciliate-E2a 148-164 58 2e-06 14.95 In-house 1-17 (275) Show / Hide 
Range on Protein: 148-164
Range on HMM: 1-17/275
Sequence Identity: 58% (10 aa)

FVLEKKIGEGAFGSVYK
. ..||||.|.|||||.
YKFIKKIGKGNFGSVYL
Kinase CDK-Un_c.AA CDK 148-165 50 3e-06 15.93 In-house 1-18 (284) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-18/284
Sequence Identity: 50% (9 aa)

FVLEKKIGEGAFGSVYKG
.   .|||||..| |||.
YEKLEKIGEGTYGVVYKA
Kinase CDK-Un_c.AA Ciliate-E2 148-166 57 9e-06 15.79 In-house 1-19 (365) Show / Hide 
Range on Protein: 148-166
Range on HMM: 1-19/365
Sequence Identity: 57% (11 aa)

FVLEKKIGEGAFGSVYKGS
. . ||||.|.||||||..
YKFIKKIGQGNFGSVYKCK
Kinase CDK-Un_c.AA CMGC 148-165 55 1e-05 13.8 In-house 1-18 (513) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-18/513
Sequence Identity: 55% (10 aa)

FVLEKKIGEGAFGSVYKG
.   ||||||..| |||.
YEIIKKIGEGTYGVVYKC
Pkinase_Tyr CDK-Un_c.AA Pkinase_Tyr 148-165 66 1.2e-05 19.72 Pfam 1-18 (270) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-18/270
Sequence Identity: 66% (12 aa)

FVLEKKIGEGAFGSVYKG
 .. ||.||||||.||||
ITFGKKLGEGAFGEVYKG
Kinase CDK-Un_c.AA Ciliate-E2-Unclassified 148-164 52 3.2e-05 14.08 In-house 1-17 (352) Show / Hide 
Range on Protein: 148-164
Range on HMM: 1-17/352
Sequence Identity: 52% (9 aa)

FVLEKKIGEGAFGSVYK
. . |.||.|.||.|||
YKIIKQIGQGGFGKVYK
Kinase CDK-Un_c.AA CDC2 148-165 50 6.7e-05 10.43 In-house 1-18 (301) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-18/301
Sequence Identity: 50% (9 aa)

FVLEKKIGEGAFGSVYKG
.   .||||| .| |||.
YQKIEKIGEGTYGVVYKC
Kinase CDK-Un_c.AA Pkinase 148-165 50 7.6e-05 18.22 Pfam 1-18 (293) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-18/293
Sequence Identity: 50% (9 aa)

FVLEKKIGEGAFGSVYKG
.....|||.|.||.|||.
YHIGRKIGSGSFGCVYKC
Kinase CDK-Un_c.AA Ciliate-E2a 474-487 57 0.000176 9.13 In-house 262-275 (275) Show / Hide 
Range on Protein: 474-487
Range on HMM: 262-275/275
Sequence Identity: 57% (8 aa)

QRISAKAALGHPYF
.||.|. || ||.|
KRITAQQALNHPWF
Kinase CDK-Un_c.AA Ciliate-E2 463-487 30 0.000404 10.02 In-house 336-365 (365) Show / Hide 
Range on Protein: 463-487
Range on HMM: 336-365/365
Sequence Identity: 30% (9 aa)

LLQA----MMQFKGRQRIS-AKAALGHPYF
|..     |.| .  .||. .. .| ||.|
LIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CDK-Un_c.AA Ciliate-E2-Unclassified 462-487 38 0.00566 6.18 In-house 327-352 (352) Show / Hide 
Range on Protein: 462-487
Range on HMM: 327-352/352
Sequence Identity: 38% (10 aa)

ELLQAMMQFKGRQRISAKAALGHPYF
.||| |.. .  .||... .| ||.|
DLLQKMLKKNPNKRITFEQILNHPWF
Kinase CDK-Un_c.AA Pkinase 462-487 23 0.006863 11.3 Pfam 268-293 (293) Show / Hide 
Range on Protein: 462-487
Range on HMM: 268-293/293
Sequence Identity: 23% (6 aa)

ELLQAMMQFKGRQRISAKAALGHPYF
...  . ...  .|..|. .| ||.|
DFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CDK-Un_c.AA CDK5 148-165 50 0.011606 3.69 In-house 1-18 (287) Show / Hide 
Range on Protein: 148-165
Range on HMM: 1-18/287
Sequence Identity: 50% (9 aa)

FVLEKKIGEGAFGSVYKG
.    ||||| .| |||.
YEKMEKIGEGTYGTVYKA
Kinase CDK-Un_c.AA CK2 148-181 26 0.012053 2.87 In-house 1-32 (288) Show / Hide 
Range on Protein: 148-181
Range on HMM: 1-32/288
Sequence Identity: 26% (9 aa)

FVLEKKIGEGAFGSVYKGSFANPQKKVLGFLVVK
. ...||| | .  |..|   . ..|.   .|.|
YEVIRKIGRGKYSEVFEGINIKNNEKC--KIVIK
Kinase CDK-Un_c.AA ULK 462-487 34 0.143819 1.35 In-house 304-329 (329) Show / Hide 
Range on Protein: 462-487
Range on HMM: 304-329/329
Sequence Identity: 34% (9 aa)

ELLQAMMQFKGRQRISAKAALGHPYF
.|.. |.|.. ..|||    . || |
DLIRRMLQYDEKDRISWEELFNHPWF
Kinase CDK-Un_c.AA ULK 462-487 34 0.278008 0.38 In-house 299-324 (324) Show / Hide 
Range on Protein: 462-487
Range on HMM: 299-324/324
Sequence Identity: 34% (9 aa)

ELLQAMMQFKGRQRISAKAALGHPYF
.|.. |.|.. ..|||    . || |
DLIRRMLQYDEKDRISWEEIFNHPWF