Protein (view, download) , Domain (view, download)
PKG2_Hsap       MGNGSVKP------------------------------------------KHSKHPDGHS
PKG1_Hsap       MGTLR-------------------------------------------------------
for_Dmel        MKIKHYPG---------------------------------------------K------
CG4839_Dmel     MACFPRLFHNR--------------------------------SKNKFTPAEDENTDTIL
Pkg21D_Dmel     MAAGMLTD------------------------------------------RER---EAIV
PKG2_Mmus       MGNGSVKP------------------------------------------KHAKHPDGHS
PKG1_Mmus       MGTLR-------------------------------------------------------
egl-4_Cele      MSSGSRPS--SGGGGGGGGASGGAGGGAPGGGGGGIRGFFSKLR------KPSDQPNGNQ
C09G4.2_Cele    MDFTR-------------------------------------------------------
PKG2_Spur       MLCL--------------------------------------------------------
PKG1_Spur       MKW---------------------------------------------------------
AqueK021_Aque   MSANNEQK----------------------------------------------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       ---GNLT--TDALRN-------------KV-TE---L------ER---------------
PKG1_Hsap       --------------------------------D---L------QY---------------
for_Dmel        ------------AVDASLSLEGSSAMG-AL-YE---A------NWLRAANQPAAPATTGT
CG4839_Dmel     ---NTQDSNVQ--------------IGKYIRREEKPLYSPIVTPS---------------
Pkg21D_Dmel     ---SNLTKDVQALRE---------------------------------------------
PKG2_Mmus       ---GNLS--NEALRS-------------KV-LE---L------ER---------------
PKG1_Mmus       --------------------------------D---L------QY---------------
egl-4_Cele      VQVGTRTFEAHELQK-------------LI-PQ---L------EE---------------
C09G4.2_Cele    ------------------------------------------------------------
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ------------LRD-------------LL-LQ---R------AM---------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       ------------ELRRKDAEIQERE-----------------------------------
PKG1_Hsap       ------------ALQEKIEELRQRD-----------------------------------
for_Dmel        KLSRQSSSAGSSFLIEGISALSKYQ-----------------------------------
CG4839_Dmel     ------------ASEAKLQRLRQQQQPPGSPPAPARWTLHSVAENGSANNGVQERKFRTN
Pkg21D_Dmel     -------------------MVRSRE-----------------------------------
PKG2_Mmus       ------------ELRRKDAELQERE-----------------------------------
PKG1_Mmus       ------------ALQEKIEELRQRD-----------------------------------
egl-4_Cele      ------------AISRKDAQLRQQQ-----------------------------------
C09G4.2_Cele    ------------------------E-----------------------------------
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ------------ELQKFKSDLERVT-----------------------------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       ------------------------------------------------------------
PKG1_Hsap       ------------------------------------------------------------
for_Dmel        ------------------------------------------------------------
CG4839_Dmel     KDKLQAQDACPSGGSAINVIRSSSKLKPVKERRPTALPTEVPSIEIEDVRDAKDTGDGMD
Pkg21D_Dmel     ------------------------------------------------------------
PKG2_Mmus       ------------------------------------------------------------
PKG1_Mmus       ------------------------------------------------------------
egl-4_Cele      ------------------------------------------------------------
C09G4.2_Cele    ------------------------------------------------------------
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ------------------------------------------------------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       ------------------------------YHLKE-------------------------
PKG1_Hsap       ------------------------------ALIDE-------------------------
for_Dmel        ------------------------------MTLENI------------------------
CG4839_Dmel     SLGERVQPGANAHVDVVDGGGKSKLKVNVNGIIDESVAHDDDYDTPSSNSIATTPVTEGP
Pkg21D_Dmel     ------------------------------------------------------------
PKG2_Mmus       ------------------------------YHLKE-------------------------
PKG1_Mmus       ------------------------------ALIDE-------------------------
egl-4_Cele      ------------------------------TIVEG-------------------------
C09G4.2_Cele    ------------------------------ALLA--------------------------
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ------------------------------KINKE-------------------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       --------LREQLSKQTVA--------------------IAELT--E-------------
PKG1_Hsap       --------LELELDQKDEL--------------------IQKLQ--N-------------
for_Dmel        --------RQLELQSRDKR--------------------IASTI--K-------------
CG4839_Dmel     VKFFIGHTQELSAQQTDDTLSCQSSDANNNSAAKLTNGVVPQEQPEREMGKQQALQAPPR
Pkg21D_Dmel     -----------------SE--------------------LVKLH--R-------------
PKG2_Mmus       --------LREQLAKQTVA--------------------IAELT--E-------------
PKG1_Mmus       --------LELELDQKDEL--------------------IQKLQ--N-------------
egl-4_Cele      --------HIKRISELEGE--------------------VTTLQ--R-------------
C09G4.2_Cele    -----------ELELKDDI--------------------IEQLR--K-------------
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   --------QQNEIAAKNEQ--------------------ISTLE--G-------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       --------------------------------------------------ELQNKCIQLN
PKG1_Hsap       --------------------------------------------------ELDKYRSVIR
for_Dmel        --------------------------------------------------ELSGYRPSAL
CG4839_Dmel     AKSSSNVSLNYLAKSQTDSQRRRRVSTMPDINIPPAPPLPPELLVPGTPLHLRKKRSMER
Pkg21D_Dmel     --------------------------------------------------EIHKLKSVLQ
PKG2_Mmus       --------------------------------------------------ELQSKCIQLN
PKG1_Mmus       --------------------------------------------------ELDKYRSVIR
egl-4_Cele      --------------------------------------------------ECDKLRSVLE
C09G4.2_Cele    --------------------------------------------------ELDEYRMM--
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   --------------------------------------------------ELKKKQKELE
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       KL----------------------------------------------------------
PKG1_Hsap       PA----------------------------------------------------------
for_Dmel        QH--------------HQQQQMHNVWVAEDQDQEHEELEDASEGKEKLASIQEPPAVNHY
CG4839_Dmel     QQQ---------------------------------------------------------
Pkg21D_Dmel     QTTNNLNVTRNEKAKKK------------------------------LYSLPEQCGEQES
PKG2_Mmus       KL----------------------------------------------------------
PKG1_Mmus       PA----------------------------------------------------------
egl-4_Cele      QK----------------------------------------------------------
C09G4.2_Cele    ------------------------------------------------------------
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   IQ----------------------------------------------------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       -------------------------------QDVVHMQGGSPLQASPDK-----------
PKG1_Hsap       -------------------------------TQQAQKQSASTLQG---------------
for_Dmel        VLDPTERPRVPRPRQQFSVKPPSLRRS----QTMSQPPSYATLRSPPKIKENLSKSSSAY
CG4839_Dmel     --------------------------------QKQQE-----------------------
Pkg21D_Dmel     RNQNPHLCSSCGMVLPTSPEFALEALSLGPLSPLASTSSASPS-----G-----------
PKG2_Mmus       -------------------------------QDVIHVQGGSPLQASPDK-----------
PKG1_Mmus       -------------------------------TQQAQKQSASTLQG---------------
egl-4_Cele      -------------------------------AQSAASPGGQPPSPSPRT-----------
C09G4.2_Cele    ------------------------------------------------------------
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   -------------------------------KQRV-----TELT----------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       ----V--PLE--------------VHR-KTSGLV---SLHSRRG-AKAGVSAEPTTRTYD
PKG1_Hsap       ----------------------------------------EPRT-KRQAISAEPTAFDI-
for_Dmel        STFSS--AAEDSQDQVVICQQPQRLMAPPPREPP---PE-PPKRVSKPLSRSQT---SV-
CG4839_Dmel     ----QQQQQE--------------IQQ--DATNSQDQMAGAEES-HKSSDSSTPKTHRVE
Pkg21D_Dmel     ----RTSADE--------------V---RPKA-------MPAAI-KKQGVSAESCVQSM-
PKG2_Mmus       ----V--PLD--------------VHR-KTSGLV---SLHSRRG-AKAGVSAEPTTRTYD
PKG1_Mmus       ----------------------------------------EPRT-KRQAISAEPTAFDI-
egl-4_Cele      ----DQLGND--------------LQQ-K-AVLP---ADGVQRA-KKIAVSAEPTNF--E
C09G4.2_Cele    -----------------------------------------NTT-RKTAISSEPDI----
PKG2_Spur       ------------------------------------------------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ----E--IMD--------------RQV-RDKS--------RPVE-HRQGISAEPTKA-L-
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       -------LNKPPEFSFEKARVRKDSS------------EKK-------------------
PKG1_Hsap       --------QDL--SHVTLPFYPKSPQ------------SKD-------------------
for_Dmel        --------QRY--ATVRMPNQTTSFSRSVVRSRDSTASQRRLSLEQAIEGLKLEGEKAVR
CG4839_Dmel     GGLIYVRPNFPIQSDIEIESIAKDEG------------TRN-------------------
Pkg21D_Dmel     --------QQS--YSIPIPKYEKDFS------------DKQ-------------------
PKG2_Mmus       -------LNKPPEFSFEKARVRKDSS------------EKK-------------------
PKG1_Mmus       --------QDL--SHVTLPFYPKSPQ------------SKD-------------------
egl-4_Cele      -------N-----KPATLQHYNKTVG------------AKQ-------------------
C09G4.2_Cele    --------------QVKRPIIGKSDA------------AFE-------------------
PKG2_Spur       -----------------------GIV------------SKQ-------------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   -------------KITQLPRYEKDQR------------SKE-------------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       ----LITDALNKNQFLKRLDPQQ-----IKD-MVE-CMYGRNYQQGS-------------
PKG1_Hsap       ----LIKEAILDNDFMKNLELSQ-----IQE-IVD-CMYPVEYGKDS-------------
for_Dmel        QKSPQISPAASSNGSSKDLNGEGFCIPRPRL-IVPVHTYARRRRTGNLKEQSSGGQEEEA
CG4839_Dmel     ----LIRTAIERNDFLNNLMDKE-----RKEMVIN-AMAPASYRKHS-------------
Pkg21D_Dmel     ----QIKDAIMDNDFLKNIDASQ-----VRE-LVD-SMYSKSIAAGE-------------
PKG2_Mmus       ----LITDALNKNQFLKRLDPQQ-----IKD-MVE-CMYGRNYQQGS-------------
PKG1_Mmus       ----LIKEAILDNDFMKNLELSQ-----IQE-IVD-CMYPVEYGKDS-------------
egl-4_Cele      ----MIRDAVQKNDFLKQLAKEQ-----IIE-LVN-CMYEMRARAGQ-------------
C09G4.2_Cele    ----TIGNALRLNSFLRNLDATQ-----IEK-ISS-AMYPVEVPAGA-------------
PKG2_Spur       ----VIRDAILLNDFTKNFDSSQ-----TRE-IVE-CMFPIDYKKGQ-------------
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ----LIFRAITANDFLKNLEKVQ-----TTE-IVE-CMFPLDFKQDQ-------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       ---------YIIKQGEPG------------------NHIFVLAEGRLEVFQGEKLLSSIP
PKG1_Hsap       ---------CIIKEGDVG------------------SLVYVMEDGKVEVTKEGVKLCTMG
for_Dmel        EKGKGWKDFYVLSQ-DRHSSFYINRIGQNYDYDYPINFNIFSPDGRVEVSREGKYLSTLS
CG4839_Dmel     ---------LIIREHEEG------------------SEIYVSAEGQYDVIRGGQLVASFG
Pkg21D_Dmel     ---------FVIREGEVG------------------AHLYVSAAGEFAVMQQGKVLDKMG
PKG2_Mmus       ---------YVIKQGEPG------------------NHIFVLAEGRLEVFQGEKLLSSIP
PKG1_Mmus       ---------CIIKEGDVG------------------SLVYVMEDGKVEVTKEGVKLCTMG
egl-4_Cele      ---------WVIQEGEPG------------------DRLFVVAEGELQVSREGALLGKMR
C09G4.2_Cele    ---------IIIRQGDLG------------------SIMYVIQEGKVQVVKDNRFVRTME
PKG2_Spur       ---------IVINEGDSG------------------AHFYVGATGTLEVSQGDRVLATMG
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ---------FICREGAVG------------------TELYVIAEGEVQVTKGGQVRTEMG
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       MWTTFGELAILYNCTRTASVKAITN-VKTWALDREVFQNIMRRTAQARDEQYRNFLRSVS
PKG1_Hsap       PGKVFGELAILYNCTRTATVKTLVN-VKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVP
for_Dmel        GAKVLGELAILYNCQRTATITAITE-CNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVP
CG4839_Dmel     PATVFGELAILYNAPRQASIEAATD-ARVWKIARETFRAIMQISGSREREENLQFLRSAP
Pkg21D_Dmel     AGKAFGELAILYNCTRTASIRVLSEAARVWVLDRRVFQQIMMCTGLQRIENSVNFLRSVP
PKG2_Mmus       MWTTFGELAILYNCTRTASVKAITN-VKTWALDREVFQNIMRRTAQARDEEYRNFLRSVS
PKG1_Mmus       PGKVFGELAILYNCTRTATVKTLVN-VKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVP
egl-4_Cele      AGTVMGELAILYNCTRTASVQALTD-VQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVS
C09G4.2_Cele    DGALFGELAILHHCERTATVRAIES-CHLWAIERNVFHAIMMESAREKTMSFKRHLKYSA
PKG2_Spur       PGKVFGELAILYNCTRTATITAVTD-AQVWAIDRKVFQLIMMKTGMQRHEEYFNFLKSVP
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   PGKLFGELAILYNCTRTATIKAKVD-TKVWALDRSCFQTIMMNHGIIRQSEYLSFLRSVP
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       LLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH----D
PKG1_Hsap       TFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPS----E
for_Dmel        IFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDT----Q
CG4839_Dmel     FLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVTIKKLDE-Q----Q
Pkg21D_Dmel     LLMNLSEELLAKIADVLELEFYAAGTYIIRQGTAGDSFFLISQGNVRVTQKLTPT---SP
PKG2_Mmus       LLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGH----D
PKG1_Mmus       TFQSLPDEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGQVNVTREDSPS----E
egl-4_Cele      IFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGE----T
C09G4.2_Cele    RFGGYPEEVLLRIAEFCTEMRYDAREELVVKP---QYVYLVCRGSVLCDDQGEVSKIVAG
PKG2_Spur       LLKDLSSDNLFKLANSLEVDFFHEGEYIIVEGSRGDTFYIISKGEVRITQSVQGQ----R
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   ELRMLNERDLMKLADVLQEDFYPQGEYIIRQRQTGETFFIISDGTVKITKQASPD----A
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       QPQLIKTLQKGEYFGEKALISDDVRSANIIAE-ENDVACLVIDRETFNQTVGTFEELQKY
PKG1_Hsap       DPVFLRTLGKGDWFGEKALQGEDVRTANVIAA-E-AVTCLVIDRDSFKHLIGGLDDVSNK
for_Dmel        EEKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHR
CG4839_Dmel     QEQIVANRKRGDYFGEQALLNADVRQASVYAD-APGTEVLMLDREAFISYLGTIKQLREK
Pkg21D_Dmel     EETELRTLSRGDYFGEQALINEDKRTANIIAL-SPGVECLTLDRDSFKRLIGDLCELKEK
PKG2_Mmus       QPQLIKTLQKGEYFGEKALISDDVRSANIIAE-ENDVACLVIDRETFNQTVGTFDELQKY
PKG1_Mmus       DPVFLRTLGKGDWFGEKALQGEDVRTANVIAA-E-AVTCLVIDRDSFKHLIGGLDDVSNK
egl-4_Cele      EPREIRVLNQGDFFGERALLGEEVRTANIIAQ-APGVEVLTLDRESFGKLIGDLESLKK-
C09G4.2_Cele    QDFELRCGRKGRFERFFVLEG----PAHLIKM-HVEQLCKALD-----------------
PKG2_Spur       EPQEVRSLQKGDFFGEKALLGEDVRTANVLAS-KGGCECLAVDRQSFNELIGNMQALQDK
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   PEETIRELGRGDYFGEKALLGDKYRTASVIAT-S-NVCCLCVDRDHFTQLIGNLVERTYK
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       LEGYVANLNRDDEKRHAKRSMSNW------------------------------------
PKG1_Hsap       A--------YEDAEAKA-------------------------------------------
for_Dmel        ---------YDDEGAME-------------------------------------------
CG4839_Dmel     PSS-----QRNDTSGRSST-----------------------------------------
Pkg21D_Dmel     D--------YGDESRKLAMKQA--------------------------------------
PKG2_Mmus       LEGYVATLNRDDEKRHAKRSMSSW------------------------------------
PKG1_Mmus       A--------YEDAEAKA-------------------------------------------
egl-4_Cele      D--------YGDKERLAQVVRE--------------------------------------
C09G4.2_Cele    ------TTDLDDEI-RP-------------------------------------------
PKG2_Spur       N--------YGDKERGATRALRGVDSTDFDPIKGLVKWISKVTKRWYNLTINTLQEDDNK
PKG1_Spur       ------------------------------------------------------------
AqueK021_Aque   D--------SEEKKLEG-V-----------------------------------------
PKG_Smoe        ------------------------------------------------------------


PKG2_Hsap       -KLSKALSLE--MIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNE--NVAF
PKG1_Hsap       ---------------KYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSE-ESKTF
for_Dmel        ---------------RRKI-NEEFRDINLTDLRVIATLGVGGFGRVELVQTNGD-SSRSF
CG4839_Dmel     ---------------KSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVAYN--Q--QAL
Pkg21D_Dmel     ----QES--C--RDEPKEQLQQEFPDLKLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIF
PKG2_Mmus       -KLSKALSLE--MIQLKEKVARFSSTSPFQNLEIIATLGVGGFGRVELVKVKNE--NVAF
PKG1_Mmus       ---------------KYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSE-ESKTF
egl-4_Cele      ----PP---S--PVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGD-KAKTF
C09G4.2_Cele    ----------------RASSTIEEADVELEDLQRVSTLGMGGFGRVELVRSA---SSRTY
PKG2_Spur       FKKSSSSEMDNTEIARIKPIQDELAAIHLNDLDIIATLGVGGFGRVELVQLAGD--KRTF
PKG1_Spur       ----------------------------------------------NWVRLDG--SNQTY
AqueK021_Aque   --------------LIEDEDTKEYSMMTLDDLVRVETLGMGGFGRVELVQLKTD-STRTF
PKG_Smoe        ----------------------------------------GLFGKVKLVFCRRT--REYY
                                                              . *

PKG2_Hsap       AMKCIRKKHIVDTKQQEHVYSEKRILEEL-CSPFIVKLYRTFKDNKYVYMLLEACLGGEL
PKG1_Hsap       AMKILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGEL
for_Dmel        ALKQMKKSQIVETRQQQHIMSEKEIMGEA-NCQFIVKLFKTFKDKKYLYMLMESCLGGEL
CG4839_Dmel     ALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDV
Pkg21D_Dmel     ALKCLKKRHIVDTKQEEHIFSERHIMLSS-RSPFICRLYRTFRDEKYVYMLLEACMGGEI
PKG2_Mmus       AMKCIRKKHIVDTKQQEHVYSEKRILEEL-CSPFIVKLYRTFKDNKYVYMLLEACLGGEL
PKG1_Mmus       AMKILKKRHIVDTRQQEHIRSEKQIMQGA-HSDFIVRLYRTFKDSKYLYMLMEACLGGEL
egl-4_Cele      ALKALKKKHIVDTRQQEHIFAERNIMMET-STDWIVKLYKTFRDQKFVYMLLEVCLGGEL
C09G4.2_Cele    ALKIMNKAHIVETKQESHVVSERRILMQC-DNDYIVRMYKTYRDSEKIYMLMEPCLGGEI
PKG2_Spur       ALKCLKKHHIVETRQQEHIFSEKKIMMES-SSPFIVKLFKTFRDQKYIYMLMEVCLGGEL
PKG1_Spur       ALKQLKKRHIVETRQQEHIMSEKNIMLEA-RCDFIVRLYCTFKDNKYLYMLLEACLGGEL
AqueK021_Aque   ALKCLRKKHIVDTRQQEHIFSEKSIMLSG-RSPFITRLYKTFRCPKYLYMLLEVCLGGEL
PKG_Smoe        ALKCVSKAKVIRLQEEEHLRNEKLFMTEM-DHPFITKLIRTYKDDKNIYLLQELTTGGEL
                *:* : * .::   : .*:  *: .:       :* ::  *::  : :*:* *   **::

PKG2_Hsap       WSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFA
PKG1_Hsap       WTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFA
for_Dmel        WTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFA
CG4839_Dmel     WTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFA
Pkg21D_Dmel     WTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENLMLDERGYVKIVDFGFA
PKG2_Mmus       WSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDADGYLKLVDFGFA
PKG1_Mmus       WTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFA
egl-4_Cele      WTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFA
C09G4.2_Cele    WTILRKKGRFDNDLTRFYCAGAMEALEYLHRKNIVYRDLKPENMLLDRNGWPKLVDFGFA
PKG2_Spur       WTILRDKGHFDDRTARFSTACVVEAFHYLHSRGIVYRDLKPENLLLDNKGYVKLVDFGFA
PKG1_Spur       -------GSFDDSTTRFYTACVTEALAYLHNKGIVYRDLKPENILLDNKGYGKLVDFGFA
AqueK021_Aque   WTILRDRGSFDDATTRFCTACVVEAFQYLHSREIVYRDLKPENLLLDNAGYVKLVDFGFA
PKG_Smoe        FFHMEKVGPLREAEASFYAGAVLLVLEYMHGKGIVYRDLKPENTLIGDNGYPKLIDMGFA
                         : :  : *  . .   : *:*   ::******** ::   *: *::*:***

PKG2_Hsap       KKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFS-GVDQM-
PKG1_Hsap       KKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFS-GPDPM-
for_Dmel        KKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFT-GSDPM-
CG4839_Dmel     KFVRQNEKTNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFR-GVNQI-
Pkg21D_Dmel     KQIGTSSKTWTFCGTPEYVAPEIILNKGHDRAVDYWALGILIHELLNGTPPFS-APDPM-
PKG2_Mmus       KKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFS-GIDQM-
PKG1_Mmus       KKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFS-GPDPM-
egl-4_Cele      KKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQ-ASDPM-
C09G4.2_Cele    KKLKNGGRTWTFCGTAEYVAPEIVLNKGHDLSVDIWALGIFMCELLTGSPPFS-STDPM-
PKG2_Spur       KKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSCDYWSLGILIFELLTGNPPFT-ANDPM-
PKG1_Spur       KRIGHGRKTWTFCGTPEYVAPEIILNRGHDLSADYWSLGILMFELLTGSPPFT-GSDPM-
AqueK021_Aque   KYIGPGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFS-GADPM-
PKG_Smoe        KRIY-NRRTYSMCGTPDYMAPEIIRRQGHGKAVDYWALGCLIFELITNTSAFNRGEDPPQ
                * :  . :* ::.**.:*::**::  :**. : * *:**  : **: . ..*  . :

PKG2_Hsap       MTYNLILKGIEKMDFP-RKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLN-GF
PKG1_Hsap       KTYNIILRGIDMIEFP-KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFE-GF
for_Dmel        RTYNIILKGIDAIEFP-RNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFD-GF
CG4839_Dmel     KIYQQILSGIDVIHMP-SRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFE-SL
Pkg21D_Dmel     QTYNLILKGIDMIAFP-KHISRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFL-GF
PKG2_Mmus       MTYNLILKGIEKMDFP-RKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLN-GF
PKG1_Mmus       KTYNIILRGIDMIEFP-KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFE-GF
egl-4_Cele      KTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFM-GF
C09G4.2_Cele    VTYNAILKGLEKWAWP-RFVTKEAIDMMLSLCKYEPTERLGFG--DIGEIRHHIWFD-NF
PKG2_Spur       KTYNVILKGIDMVEFP-RKIPRSAGNLIKRLCRDNPGERIGYQKNGISDIKKHKWFQ-GF
PKG1_Spur       KTYNIILKGMDMIEFP-RKITRNAANMIKKLCKDNPTERLGYQKSGLKDIQKHKWFD-GF
AqueK021_Aque   RTYNIILKGIDVVDFP-KKITRSAQNLIKKLCRDNPAERLGYLRNGLNDIKGHRWFQ-GF
PKG_Smoe        LVFHRIIDG--RVKFP-PYVSSDCADIVRKLLDPNPETRLGCRKRGAADIKEHPFFAKSV
                  :  *: *      *   :      ::  *    *  *:*    .  :*: * ::  ..

PKG2_Hsap       NWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKG-M-----------------PPDELS
PKG1_Hsap       NWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEP-----------------PPDDNS
for_Dmel        YWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGP-----------------PPDDVT
CG4839_Dmel     DWQRLKLKQLPSPIKRPLKSWTDLQYFGPSGVENDYE-----------------PPEELS
Pkg21D_Dmel     DWDGLASQLLIPPFVRPIAHPTDVRYFDRFPCDLN-E-----------------PPDELS
PKG2_Mmus       NWEGLKARSLPSPLRRELSGPIDHSYFDKYPPEKG-V-----------------PPDEMS
PKG1_Mmus       NWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEP-----------------PPDDNS
egl-4_Cele      DWEGLRSRTLKPPILPKVSNPADVTNFDNYPPDND-V-----------------PPDEFS
C09G4.2_Cele    DFVGFRAHRIRPPFIPSVANDIDTSNFDTFPAFDNFASGSDESGWDIDFFDNFASGSDES
PKG2_Spur       DWEGLRKQEIAAPLPPKVKGSSDCSNFDSYPKDVD-I-----------------PADETS
PKG1_Spur       NWEGLRKRSLTPPIVPTVRSNSDASNFDDYPPDHEAA-----------------PEDDTS
AqueK021_Aque   DWEGLKKRVVVPPIVPNVRGATDTSNFDHFPASQEDI-----------------PPDDLS
PKG_Smoe        NFQLLIRQKEEPPVSFTELM----------QVTLH-FPSAD----------------DS-
                 :  :      .*.                                           :

PKG2_Hsap       GWDKD--------------F
PKG1_Hsap       GWDID--------------F
for_Dmel        GWDKD--------------F
CG4839_Dmel     GWDKD--------------F
Pkg21D_Dmel     GWDAD--------------F
PKG2_Mmus       GWDKD--------------F
PKG1_Mmus       GWDID--------------F
egl-4_Cele      GWDEG--------------F
C09G4.2_Cele    GWDID--------------F
PKG2_Spur       GWDEH--------------F
PKG1_Spur       GWDKD--------------F
AqueK021_Aque   GWDKDFGEIQRTPAWCLRGY
PKG_Smoe        --SKT--------------R
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