Slob_Hsap MAFMEKPPA-------------GKVL-LDDT------------------------VPLTA
CG8726_Dmel MAVFASRYE-------------RKLP-IDDT------------------------QALSC
Slob_Dmel MFKFNKAAQ-------------QQ-R-IDNRNSAVTGHDPFVRPPVPEKKVRN----IMK
Slob_Mmus MAFMEKPPA-------------GKVL-LDDT------------------------VPLTA
SLOB1_Ddis MDSSTANSSGTAISKAEWKPDQSSLECNDCQ------------------------LPFTL
SLOB2_Ddis MEYYYYII----------------------------------------------------
Slob_Spur MAVFEKRKS-------------SKLT-LDDT------------------------ITLTC
AqueK206_Aque MVFECSSNS--------------T-C-WENCNLVCIGLTA----GGSLIVLVLCIVIITA
AqueK207_Aque MMAASASSKKDRSSV-LEKVD-RRLS-VDPT------------------------IPLTA
*
Slob_Hsap AIEAS-----------------QSL---QSHTEYIIRVQRGISVENSWQIVR--RYSDFD
CG8726_Dmel EITAV-----------------QEV---AGHTEYLLRVWRGASNKNYWTVLR--RYNDFD
Slob_Dmel KLHKA-----------------NGLKRSNSAIE--FDVS-ALTAANRRQIYSSNRSASSE
Slob_Mmus AVEAS-----------------QSL---QSHTEYIIRVQRGISAENSWQIVR--RYSDFD
SLOB1_Ddis IRRRHHCRKCGSIFCDSCSSFYSIL---PIEYGYTGQQRLCRSCNNSFEQKK--------
SLOB2_Ddis -IAAV-----------------GGF---AILTFIIIVVLR--------------------
Slob_Spur SIEAA-----------------QNL---ESHTDYVIRVQRGPNPENSWQINR--RYSDFV
AqueK206_Aque IVCCC-----------------CCL---YRRRS--RRLRYTPLRDPSGSVVT--TYNPAT
AqueK207_Aque TILTY-----------------KIV---QSHVEYVIRVQRGPNPDDSWDVER--RYSDFA
.
Slob_Hsap LLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNY---LNVITTNHILSNCELVKK
CG8726_Dmel RLDKSLRVSGIELPLPRKRIFGNMRPEFIAERKQALQEY---INAVLMNPILASSLPAKR
Slob_Dmel QDNSDLSEHSEKSPLVSARL-DNLARLFFSKSMPAETGSRDTIDSVLTTR--PNIKYQYS
Slob_Mmus LLNNSLQITGLSLPLPPKKLIGNMDREFIAERQRGLQNY---LNVIMANHVLSNCELLKK
SLOB1_Ddis ------------------------------------------------------------
SLOB2_Ddis -LKKSQ---KMREPLLPKE-KGN---VFVYKRDTQVQE----------------------
Slob_Spur TLHDGLKVSGMELGLPPKKVFGNMEREFIAERQQALQGY---LNRILSHQLLSSCFLVKR
AqueK206_Aque RRNQDIRSGSISDAVAEEGLYEAMQRQR--------------------------------
AqueK207_Aque ALNQALQISGVQVNLPPKRMFGNTDKQFVTERQQGLQEY---LNIIAKHPFIAASLDLKL
Slob_Hsap FLDPN-------NYSANYTEIALQQVSMFFR-SEPKWEVVEPLKDIGWR---IRKKYFLM
CG8726_Dmel FVDPE-------SYSQSFHDHAVQNAMLCLR-NDTTWSLGGSMGAIGWR---LRKHYFKV
Slob_Dmel ALDSGNGIVERSPRERAQREKALNATQEWIQGANGRYEVIAHLDEIGSR---HGKNWFLV
Slob_Mmus FLDPN-------NYSANYTEIALQQVSMFFR-SEPKWEVVEPLKDIGWR---IRKKYFLM
SLOB1_Ddis ----------------QYFETDALVAQFQLR-STAQFEYSKPLQDIGHTKHGLRKSYCMA
SLOB2_Ddis -----------------KEEQVMMNARLYLR-ST-IYSLQDKIPKFGSR---SDKVYFGV
Slob_Spur FLDPT-------NYAPNSVEDALQHVSMFFR-SEPHWDVVEPLRDIGWR---IRKTYFMV
AqueK206_Aque -----------KERESTRRETGLLNCQFYLR-SNQKYVLETHLPDIGSR---ISKSWFMV
AqueK207_Aque FLDPH-------NYSDKCHEIALRNVSMFFR-SNPEWAIVESKKNIGWR---INKHYYLI
: :: : :* * :
Slob_Hsap KIKNQ--PKERLVLS-------------------------------------WADLGPDK
CG8726_Dmel TTKPPEKSSNKQLVKSGSQTHQSKHFAAGSSNGSGHSIDAGTLDPGSEVVAEWLEYGPDK
Slob_Dmel TDASVRT---DRLQT---------------------------LLPLPPDCVAFEDLPPNE
Slob_Mmus KIKNQ--PKERLVLS-------------------------------------WADLGPDK
SLOB1_Ddis KNSMG--GGEECVVS-------------------------------------IITPTPSS
SLOB2_Ddis LGNSLNKLENDRIMA-------------------------------------MVPVSKHW
Slob_Spur RPKSQ--PKVKQVLA-------------------------------------WSYYGPDK
AqueK206_Aque RPISGGQFNPPFLLT---------------------------MSPISQQCRL-NLQGTDK
AqueK207_Aque GSKGDG-FKYKRILT-------------------------------------WIEPGPDF
:
Slob_Hsap ----YLSDKDFQCLIKLLPSC-LHPYIYRVTFAT----ANESSALLIRMFN-EKGTLKDL
CG8726_Dmel ----FIDEKEIGGIMKSLMGL-QHPHIEPVLLA----AHTENGCLVIRKFH-KHGTLKDV
Slob_Dmel ----CA----REILMELLGSL-HHPYIYPVLDLGFLRNSSYNYACLVTPFN-SRGSLKDL
Slob_Mmus ----YLSDKDFQCLIKLLPSC-VHPYIYRVTFAT----ASESSALLIRAFN-EKGTLKDL
SLOB1_Ddis CPWSMSNEKKKRKFEKTLLSL-KHPYILTPINVEV--SGANDKILVIRTFF-KQGSLRDQ
SLOB2_Ddis -PIPLNSEAGRTTFRTIIKSLEIHPFISVPLLVDF--IPEKHVAVSVRPFYADRGSLRDF
Slob_Spur ----DLDYKDLVPIMKLLPTI-QHPFIYPVTYVS----ASDSGGLAIRTFH-GTGTLKDF
AqueK206_Aque ----HV----MN-----------------------------------RLF---------R
AqueK207_Aque ----CVPERELEYLLKILVDL-KHPNILSPLSAT----YNGTGLLVTREFC-PKGSLRDY
*
Slob_Hsap IY-KAKPKDPFLKKYCNP----------------KKIQGLELQQIKTYGRQILEVLKFLH
CG8726_Dmel LCMAANPKNTFLSKYGNP----------------KGRTALSMKQVATYGKQILEALIFLH
Slob_Dmel IY-KAQWNEPWARKYTR------------------KPNGLPVSQVQRLGRQILEALLFLK
Slob_Mmus IY-KAKPKDPFLKKYCNP----------------KKTQGLELQQIKTYGRQILEALKFLH
SLOB1_Ddis VY-KSKPLSPYDTKYIYKQPKSSSSSSSSSSSSSQSQSVLPIKSIQKYCKQILESLLYLK
SLOB2_Ddis IH-KSKPKMPYADKYDT-------------------HLQLNEKIVSKFGRQILEALIFLK
Slob_Spur IC-KAKPKAHYLKKYCLP----------------KSYTAFNIMNIKSYGRMILEALKFLH
AqueK206_Aque IL-ETTPSLPWSTKYSV------------------RRSGLRTHQIQNFGRQILEAVLFVH
AqueK207_Aque MH-KSGPQH-YLKS-CCP------------------TSPLDLGLIKTYGYQVLCVMEYLL
: : : . : : :* : ::
Slob_Hsap DKGFP-YGHLHASNVML--DGDTCRLLDLENSLLGLPSFYRSYFSQFRKINT-LESVDVH
CG8726_Dmel SKGYA-YGHLHSGNIVI--VDDCVKLLDIENFLLGVPAFYRPFFMQHSKIHA-IETIDVY
Slob_Dmel ERGFPLHGHLHSGNVIL--QNGAARLSGLENGLLGLSSRINAVMW-SRSVTE-IENVDIV
Slob_Mmus DKGFP-YGHLHAANVML--DGNTCRLLDLENSLLGLPSFYRSYFTQFRKINT-LESVDVH
SLOB1_Ddis SKGIQ-FSHLHLSNILINQSNDTCQLVDIENCLLGMKPLFNDYIYGIGLPQSFKDNLEVI
SLOB2_Ddis NHNFP-YFHLNSANVLV--DDQICLISDYENSFLGLEPRFSDFIRQ---HNE-KIDPDVL
Slob_Spur EKGLP-YGHLHAGNVIL--EGNACRLLDIENTLLGLPFFYRGYLSHFRKINT-TEAVDVY
AqueK206_Aque ELGFKPFGQIQSGNIYL--EGGRCRVSGIDNAILGYKPRVSRNV----K-TY-KENIDSV
AqueK207_Aque SKGFV-LGHITSGNVMII-DYGLCKVSDLENCLAGLPVFHRTFLLELRKVQG-AEAEAVY
. . :: .*: : : . :* : * .
Slob_Hsap CFGHLLYEMTYGRPPDS-VPVD-------S-FPPAP--SMAVVAVLESTLSCEACKNGMP
CG8726_Dmel CFGHVLFEMAMGYPLQES-VVR-------Q-ITEC---PEALKCLLESILSKEACKAGLP
Slob_Dmel CFGHLLYEMCTGQELTTPKPSMRVLEMELQHYPQIGQTRKQILEILGLIFE--PPSGVCP
Slob_Mmus CFGHLLYEMTYGRPPDS-VPVD-------S-FPPAS--SLAVVAVLESTLSCEACKNGMP
SLOB1_Ddis CFGHCLFEMIIGIPLGDHSNIN-------S-FIPLF--PDKVFLLLQQIFS-----EKTP
SLOB2_Ddis SFGLVLFEMACGYEMENPHSVD-------ISIPAHC--YPEVRKVLEAIFKP--FYGTPI
Slob_Spur SFGHVLYEMTFGSPLNV-ASKD-------D-FPHTI--PPPIKSVLESILTTEACKTKLP
AqueK206_Aque MFGHLLFELGSGKELSNPAPIE-------SDYKNVK--NQQVVEVLQFIFQ----SRIPP
AqueK207_Aque SFGHLLYEMAYGRILET-ATIE-------A-LPPYPAVDSNLGTLLMSLLSVAG-VKALP
** *:*: * : :* :
Slob_Hsap TISRLLQMPLFSDVLL----------TTSEKPQFKIPTKLKEA-LRIAK------ECIEK
CG8726_Dmel TLEQLLGHRFFLQYASTESA---GAAANAEKPYFKLSLNAKEL-LKQAA------IKSEN
Slob_Dmel SVEDLVLCDLFRSIDLREL----------RGPCFST---IKP------------------
Slob_Mmus TVSRLLQMPLFSDVLL----------TTSEKPQFKIPTKLKEA-LRIAK------ECIEK
SLOB1_Ddis TLEELVKNPWFEVTTT----------IE--QQSLQN-GKLKKSQLTFIK------DNSN-
SLOB2_Ddis TLEELSKMDFFSYHKFKNLPLHRLTYTSRERDMMDAVIKLNKT-FLSTNSKPNSKDLSQP
Slob_Spur TVDDLLADPLFSDVTF----------PERDRPQFRIPSKLKEP-LKAAK------SEVEK
AqueK206_Aque TIDEILQLPFFQNAR-TSV----------DNPEGI-------------------------
AqueK207_Aque KISDLVSHLFFAGQ-L----------PLTEKPSLKVPSRLKEF-LVSMR------DKVDA
.:. : *
Slob_Hsap RLIEEQKQI------HQHRRLTRAQSHH------------------GSEEERKKRKILAR
CG8726_Dmel RLRDEQKSV------KNQKRIVRVQELM------------------SSEEEKRKSKQKAK
Slob_Dmel SLSRST---------------------L------------------NLLQAVKKR-QCAS
Slob_Mmus RLTEEQKQI------HQHRRLTRAQSHH------------------GSEEERKRRKILAR
SLOB1_Ddis KFESPKVSLSGSFSSSNISKLSSSSSNNNSNNNNNNNNNSNTFNNISSNDDKRKSMK---
SLOB2_Ddis KLKDLKKQ-------KKRKQLVFTQSFE------------------PIKMESQNGGGAAG
Slob_Spur RLQEDSRVV------SSFRRLSKAQAHH------------------NSDEEKRRRKKAHL
AqueK206_Aque RLDEDI---------------------I------------------ELIQKSRRYRSKGG
AqueK207_Aque RLQEDQRKL------SHFLRMSKAHDSL------------------MSEEEKKKRRKKMR
: :.
Slob_Hsap --------------------------------------------KKSKRS----------
CG8726_Dmel --------------------------------------------LEHKQSK---------
Slob_Dmel --------------------------------------------L---------------
Slob_Mmus --------------------------------------------KKSKRS----------
SLOB1_Ddis --------------------------------------------LPSSTSL---------
SLOB2_Ddis GEYGNEGGYAISTSSSLPSNFLANVKPANSTSYSLLSNTTTNTTNTSTSSSLNSSFN---
Slob_Spur ---------------------------------------------KKRMSE-QN------
AqueK206_Aque --------------------------------------------KGRKAS----------
AqueK207_Aque --------------------------------------------KQMTQEADQTLAEAYP
Slob_Hsap --------ALENSE----EHSAKYSNSNNSAGSGASSP------------LTSPSSPTPP
CG8726_Dmel ---------LKQQSSIQTN-NGRLSLVAATAAAASSSTTVVGELCGTDSFNRSDSTPEEP
Slob_Dmel ----------------------------GHSLSEA-------------------------
Slob_Mmus --------AVENSE----EQPVKHSNSNNSAGSGASSP------------LTSPSSPTPP
SLOB1_Ddis ---------LNNSF-NLS------NNNNPSSPSTSTIS------------PNSSLISSPP
SLOB2_Ddis --------S-NVST-SYS---NATTTTNTTSASSVSPP------------ISSPPPPPPP
Slob_Spur --------IGEANN----STPPAQTNG-NHAGNGAV------------------PTPPPP
AqueK206_Aque -------------SSTYSN-EG------YYRSSLFSTTPQ-----------VADSTV--T
AqueK207_Aque TSKLTKQLSVPSSS-APTNRPSSKASSKTSSASTASTA------------PKSPSTSKSP
Slob_Hsap STSGIS-ALPPPPPPPPPP---------AAPLPP-ASTEAPAQLSSQ----AVNGMSRGA
CG8726_Dmel TTLAGIKS-PPLTPGPHLGSIYQQELPSTTGAPVERQSSTPNMLSEDAEGGDGDEPTRSA
Slob_Dmel ------N-SPCTPPSTP--------HDRR--------T-----------------GVLP-
Slob_Mmus STAGLSSALPPPPPPPPPPP--PP----AGPSPT-SATEMPAPFLPQ----PVNGVNRGA
SLOB1_Ddis KTPILQTFTPP-PPPPPPK-SAPP------PPPPPSSSKLP-----------PSSSSRNS
SLOB2_Ddis PPPSKS-SGPPPPPPPPPKSSGPP------PPPPPKSSPP-----------PPADGSRKG
Slob_Spur STPAQPPPVPSAPAPPPPPS--------QGPAPPPVSSNQ--------------PPERGA
AqueK206_Aque SSAANESSLPP-PPPPP--------PPSN--------T-----------------NDKSA
AqueK207_Aque STTK-SPSTPSVPAPPTTQA--PE------PTPPPA-----------------KTGERGA
* .. .
Slob_Hsap LLSSIQNFQKG-TLRKAKTCDHSAPK------------IG
CG8726_Dmel LLESICKFNRG-SLRKVRSN-------------------D
Slob_Dmel --AP----------------YEVFR-------------MY
Slob_Mmus LLSSIQNFQKG-TLRKAQTCDHSAPK------------IG
SLOB1_Ddis LLESIRNADNAKKLKKTTPNTKPKSSIGPHSLKPSSTKKK
SLOB2_Ddis LLSSIESFSSS-KLKKTKTVDKSGPL----------LKKS
Slob_Spur LLSSISGFNKG-GLKKTQTADKSGP-------------KV
AqueK206_Aque LWSDIHK--GK-TLRPTVTDDRSAP-------------MI
AqueK207_Aque LLNSIESFAKG-KLKKTVTKDRSGP-------------FL