Protein (view, download) , Domain (view, download)
TTK_Hsap         MESEDLSGRE-LTIDS-------------------------------IMNK---------
MPS1_Scer        MSTNSFH-DY-VDL-------------------------------KSRTN--TRQFSDDE
CG7643_Dmel      MTTPVPRR----------------------------------------------------
TTK_Mmus         MEAEELIGSS-VTIDS-------------------------------IMSK---------
TtkA_Ddis        MDTHQSFNEN-QHPNFNSG--------------------N-----HGGIN--MNRFQRFS
TTK_Spur         MTYHTECMSE-LARHGNKPCEWLAYLSLVESHTVHAEETSRYRFLSLAFNRATKQIPIDK
CC1G_03033_Ccin  MSTSPSISPP-RTPNDNRP--------------------T-----ASTSN--SP-SSDDS
TTK_a_Smoe       EELHSLRS----------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       MFGAPGSVPKDGDPPADR----------------------GYRPMRGYFNW---------


TTK_Hsap         --------------------VRDIKNKFK-NEDLT--DEL--S---LNKISADTTDN--S
MPS1_Scer        EFTTPP------------------------------------K---LSNFGSALLSHTEK
CG7643_Dmel      --------------------TKDMMALGL-DSDSE--DDF--NTPY--------------
TTK_Mmus         --------------------MRDIKNKI--NEDCT--DEL--S---LSKICA---DH--T
TtkA_Ddis        KPTISP----------IQQQQQPQP---------Q--QPS--S---IIQRQSIIMTQPQP
TTK_Spur         YCEDPAYARIIIKLAHLKA-SREEMAQMM-NGNTR--DNTTGNLTSLARFH-SMTDH--T
CC1G_03033_Ccin  SIIDDL------------------------------------S---FDYV----YDD--N
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       --------------------TRDIAKEVPTTPDATEGDQE--E---SSS---SLADT--K


TTK_Hsap         GTV-----NQIMMMANN---PE--DWLSLL-LKLEKN---SVPLSDALLNKLI-GRYSQA
MPS1_Scer        TSA-----SEILSSHNN----D--KIANRL-EEMDRSSSRSHP-PPSMGNLTS-GHTSTS
CG7643_Dmel      ----------------R---PR-----QAA-A---------------------GERKQQP
TTK_Mmus         ETV-----NQIMRVGNT---PE--NWLNFL-LKLEKN---SSPLNDDLLNKLI-GRYSQA
TtkA_Ddis        QPQ-----PQMIPIFRE---PN--EWYKLIDMEMNKFNNESRP-SPEYIKYLT-QLFQQA
TTK_Spur         ECM-----SELARHGNK---PC--EWLAYL-SLVESH---TVHAEETSRYRFLSLAFNRA
CC1G_03033_Ccin  GNV-----VRLSRKSNSTSPPT--DQESLP-DSALDN---DSPAGSPLNRQSL-SRSESA
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       ACVTPVGQNEVRGVAH---PPKPSHLQRQH-SSVQHV---VAPLKKEAENTVI-KKSPIF


TTK_Hsap         IEALPPD-KYGQNES---------------------------------------------
MPS1_Scer        SHST--------------------------------------------------------
CG7643_Dmel      VASFQVQTRGKENEPHPL-P----------------------------------------
TTK_Mmus         IEVLPPD-KYGQNES---------------------------------------------
TtkA_Ddis        LDSL--------------------------------------------------------
TTK_Spur         TKQIPID-KYCEDPA---------------------------------------------
CC1G_03033_Ccin  QSILQG-TSAAATDPKPARPFQRVASTPSYLLPTAAATSRAAVTRGGPRRIIEDSHNRER
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       LE-EPPQ-KKLNYAS---------------------------------------------


TTK_Hsap         ------------------------FARIQVRFAE-LKAIQEPDDARD-YFQMARANCKKF
MPS1_Scer        --------------L--------FG--------------------------RYLRNNHQT
CG7643_Dmel      ------------------------INMLPRRVSE-LTMMDSDSDEED-IKSNHNLNCAIL
TTK_Mmus         ------------------------FARIQVRLAE-LKAIQEPDDARD-YFQMARENCKKF
TtkA_Ddis        --------------EHKNT--PEFYLFLLN-RATFQSKIGENEDAKG-TLKYMKVLKMES
TTK_Spur         ------------------------YARIIIKLAH-LKATHDVDDGRM-MFKFARANVRKQ
CC1G_03033_Ccin  QEPIVRSRQTFDYATRDSYAHQEEKENI---LAEM-DERPQLVNRRNSPPLIARSTASRF
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       ------------------------YSTSSKRSS---------------------------


TTK_Hsap         AFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPL----EMLEIALRNLNLQKKQ-----
MPS1_Scer        SMTTMNTSDIEINVGN------SLDKSFE----R--------------------------
CG7643_Dmel      NDSFVLSPSQELTNSNSNIT-----TRRTPSAAP--------------------------
TTK_Mmus         AFVHVSFAQFELSQGNLKKSEQLLHKAVETGAVPL----QMLETAMRNLHLQKKQ-----
TtkA_Ddis        FEVFVLLSEIESKSFRFSKARSIINRGIQKIPSRS----KEFEGFLMVIDIQEDEFSRNG
TTK_Spur         AIVHLEAAKFEEIHGDMKKCLGILEKGFKVTSDPR-----LSEALHRV-KNGLPI-----
CC1G_03033_Ccin  SSARISYSTIGGSLNGRPLADVPVQRTARQPPTGLTRPGRLMKSSLTSL-----KYS---
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       -----------------------NDQSTKRSASPQ----TIDTAATKVLGLTQQ------


TTK_Hsap         --------------------------------LLSE--------EEKKNLSA-STVLTAQ
MPS1_Scer        ------------------------------IRNLRQNM-KEDITAK--------------
CG7643_Dmel      ---------------------------------LKQSD-SNLSF----------------
TTK_Mmus         --------------------------------LLPE--------EDKKSVSA-STVLSAQ
TtkA_Ddis        CIISNNNNISFNNGDVNNNSIIMNENDQPMVINLNPQQ-QQQQQQQPYEISSSSSL--MS
TTK_Spur         --------------------------------LLDSQE-PMESQDGPQTMSA-APA-PVQ
CC1G_03033_Ccin  --TSNQDRLSDVV-----------ESSDYE-----------HKQQGLPEPNPYAPPASDT
TTK_a_Smoe       ------------------------------------QQ-QEVKVAEGANV----------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       ---------M--------------------T-ILDNKEFQYNKTLGSTEVKSETKVVVAT


TTK_Hsap         ES-------FSG----------------------------------------------SL
MPS1_Scer        ------YAERRSKRFLI-SNR-----------------------TTKLGPAKRAMTLT--
CG7643_Dmel      -----------------------------------------------------------L
TTK_Mmus         EP-------FSS----------------------------------------------SL
TtkA_Ddis        TPASSRHLSNRSSIVPT-PNS-----------------------STKLSESIKTIGLRSV
TTK_Spur         PS----HNASEEKISPHVPSSMEYVDTTISFR------------------------RPEV
CC1G_03033_Ccin  EPED-------EPLE---PSA-IPLRSSLNPRQRKELNINAQAASLAQSGSNRPR--RSA
TTK_a_Smoe       ----------HDKVV---TES-----------------------K---------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       TP-------PSEVLTPLVPTSS-----------------------TPQSAAVQKK-----


TTK_Hsap         GHLQNRNNSCDSRGQTTKARFLYGE----NMP-PQDAEIGYRNSLRQ--TNKTKQSCPFG
MPS1_Scer        -----------------------NIF-DEDVPN---------------------------
CG7643_Dmel      GRFNDMGINCSSQGSP--------------------------------------------
TTK_Mmus         GNVQNRSISCESRGQAGAARVLYGE----NLP-PQDAEVRHQNPFKQ--THAAKRSCPFG
TtkA_Ddis        QPRRVIHKQTTTNFNTTTTTIPENSY-DDDADQPMDHDGNNNNNFRIHSNNNNNSSANSS
TTK_Spur         GSRISSHPKCDSDHESDTMPINAGS----RFSGLQTPDVANKFGVFG--SSRRKRSGNIG
CC1G_03033_Ccin  SLSDALYPHDDYQLQVAAPPTHGHSRPGTS------------LGLNAES--GPRR----V
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       -------------------------------------------------PSQSLRKGIFG


TTK_Hsap         ---RVPVNLLNSP-----------------DCDVKTDDSV------------------V-
MPS1_Scer        -----------SPNQPINARETVELPL--EDSHQTNFKERREN-----------------
CG7643_Dmel      ------------------------------------------------------------
TTK_Mmus         ---RVPVNLLNSP-----------------DFYVKTDSSA------------------V-
TtkA_Ddis        YNK----SENDEDDQDEED---EEEEDEDEDDDEEDEEEYEDNNNNNNNNNNNNNNNNNN
TTK_Spur         MPMRVSRTSLPQL---KKE---SKDDDDDDDDDDDDDDDI------------------RP
CC1G_03033_Ccin  YPEERERQELEAHKKLRRE---HEDDRQS-----------------PSPTHGHPQHQR--
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       ---QTDINYNTTI-----------------DFQ---------------------------


TTK_Hsap         ------------------------------------------------------------
MPS1_Scer        -TDYDSI-DFGDLNPIQYIK----KHNLPT------------------------------
CG7643_Dmel      ------------------------------------------------------------
TTK_Mmus         ------------------------------------------------------------
TtkA_Ddis        NNNNNNN-NYFKYNRQQYIL----NNDSDT------------------------------
TTK_Spur         LKCSPQETKPGPLAPI-----TEKTNESDSGVQTTPRDLTQTDRNPFTFKERTIEMGAES
CC1G_03033_Ccin  -----------------LVANGHRRRDSD-------------------------------
TTK_a_Smoe       --------------------------ESD-------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       ------------------------SGDAANT-----------------------------


TTK_Hsap         ------------------------------------------PCFMKRQTSRSECRDLVV
MPS1_Scer        ----------------------------------SDLPL---------------------
CG7643_Dmel      -----VANSEKQVAKKTAPTLQ-AAPSATERRPLQETETPLRNELPSTSKTK-PDADFIT
TTK_Mmus         ------------------------------------------TQLTTRKGSG-PDRDAIL
TtkA_Ddis        ----------------------------------STNPN---------------------
TTK_Spur         TVPGQLANSMQRH-DPLMSVQQMAHPQMPVQPQWQQQ--QPQHSVPQMSMPH-VDVQRMQ
CC1G_03033_Ccin  ------------------------------------------------------------
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       NIP--LPPVTGQVLEK-LPTKQVVYPCAPQVPDL--------------------------


TTK_Hsap         PGSKP-----SGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLA
MPS1_Scer        ------------------------------------------------------------
CG7643_Dmel      PQVRTIGSTLAGKSRSAVSNDFRAQKVLFQTPMTVS-RAAPV-ASDSISFS--LCDTI--
TTK_Mmus         PGSRP-----RGSDSYELRGLKPIQTIYLKDSLVSNEKSSEL-MSDLIALKSKTDSS-LT
TtkA_Ddis        ------------------------------SPASSNSSVNDIINSISITDDSKLDYENNV
TTK_Spur         PLQ----------------------QQL--------------------------------
CC1G_03033_Ccin  --------------------------------------------------TLR------G
TTK_a_Smoe       --------------------------------------------------SSR------G
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       ------------------------------------------------------------


TTK_Hsap         KL-EETKEYQEPEVPE------SNQKQWQSKRKSECIN--------QNP----AAS-SNH
MPS1_Scer        ---ISQIYFDKQRE-E-----NRQAAL-RKHSSRELLYKSRSSSSSLSS----NNLLANK
CG7643_Dmel      --------TESPDIPEPPKKAEPPKSQHPSKKSLDHVF--------RES----D-----K
TTK_Mmus         KL-EETK----PEIAE------RRPMQWQSTRKPECVF--------QNP----AAF-APL
TtkA_Ddis        KL-QQQQQQQQQQQ-Q-----QQQQQQ-QQQQQQQYIQQQQQQQPKIHP----QRF-SLQ
TTK_Spur         -------------------------------------F--------QQ------------
CC1G_03033_Ccin  -LAPPN----------------SA---------GTVGSPTVMDMPNGRPSPTGHRF-PHG
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       -----------------------------------------------QP----VNTGSQQ


TTK_Hsap         WQIPELARKVNTEQKHTTFEQPVFS---VSKQSPPISTSKWFDPKSICKTPSSNTLDDYM
MPS1_Scer        DN---------SITS----NNGSQP---RRKVSTGSSSS--------------KSSIEIR
CG7643_Dmel      DNVPD-----------------KVD---------------NVEPKE--------------
TTK_Mmus         RHVPDVTPK-------------------ADKESPPISVPKWLDPKSACETPSSSSLDDYM
TtkA_Ddis        NNTPTTTT---TTTAATNVQNPSSS---SSYISPPLSSQ--------------SSELQHQ
TTK_Spur         ---P------------------TPA---------------GMQPNY--------------
CC1G_03033_Ccin  RSSPAATV--------RGRQSPQTV---KGRVSPPATKGR-------------VSPANAG
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       YRIPMVSLTSQ-NVTYTTSNQPTMAGESRAAITAPSTRQ--------------NSDGTVA


TTK_Hsap         SC--FRTPVVKNDFPPACQ-LSTPYGQ---------------------------------
MPS1_Scer        RA--LKENIDTSNNSNFNS-PIHKIYKGISRNKDSDSEKRE------VLRN------ISI
CG7643_Dmel      ------------------------------------------------------------
TTK_Mmus         KC--FKTPVVKNDFPPACP-SSTPYSQ---------------------------------
TtkA_Ddis        RR--HSIQAQRANKPPVIP-PPSKLHQNNLQQQQQQQQQQQQQQQQQQQQQLLLQQQALL
TTK_Spur         ------------------------------------------------------------
CC1G_03033_Ccin  NRLGVSRDAGKHRRSPTAPEPPTTSGQIGGHEQPPGSKTWGGSEREDEFDPASSGEK-DR
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       RV--HDIDD--PDYTKAL------------------------------------------


TTK_Hsap         ----------------PACFQQQQHQI----------------------LATPLQNLQ--
MPS1_Scer        -NANHADNLLQQENKRLKRSL--------DDAITNENINSKNL-EVFYHR--PAPKPPVT
CG7643_Dmel      --------------------------L----------------------VSIPAVAVP--
TTK_Mmus         ----------------LARLQQQQQQG----------------------LSTPLQSLQ--
TtkA_Ddis        QQQQQQQILLQQQQQQQQQQQ--------QQQQQQKQ-QEQQLKKTNMQP--PPPKQPQP
TTK_Spur         --------------------------Q----------------------LPAPQMVAP--
CC1G_03033_Ccin  EKERERQ-LEAQRERRERREQQQQQQPPPQPPPQQLQ-PYAQVPQAIAQPAAPAPQPP--
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       -------------------------KF----------------------LEKYMSSLA--


TTK_Hsap         --------------------VLA--SSSANECISVKGRIYSILKQIGSGGSSKVFQVLNE
MPS1_Scer        KK-----------VEIVEPAKSA-SLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGS
CG7643_Dmel      --------------------PEQ-PSHKTSNILKIKNHEYTIDKKLGCGGSSSVFLARRS
TTK_Mmus         --------------------ISG--SSSINECISVNGRIYSILKQIGSGGSSKVFQVLNE
TtkA_Ddis        QTQTQQQQKNINNSEIVDKEKSFEVAKSWSEVAMVNGKPYLRIEFIGKGGSGKVYKVLSG
TTK_Spur         --------------------V---PQPKSKNLIQVNGKGYSIIRLIGKGGSSKVFQVLSE
CC1G_03033_Ccin  --------------------IPA--PNQLNRHIVVNKKAYARIDIIGKGGSSRVFRVLNH
TTK_a_Smoe       ------------------------KTRENANFVWVNNKRYQKLGKIGSGGSSHVFKVIAQ
TTK_b_Smoe       -------------------------------FVWVNNKRYQKLGKIGSGGSSHVFKVIAQ
GK068_Glam       --------------------LLF--RKIPVQILYINKKVHLVIEQIGAGGYGHVYKALQP
                                                   ::   :     :* ** . *: .

TTK_Hsap         K-KQIYAIKYVNLEEA-------DNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEIT---
MPS1_Scer        G-NRVYALKRVSFDAF-------DDSSIDGFKGEIELLEKLKDQ-KRVIQLLDYEMGD--
CG7643_Dmel      DSGNEFALKVVDLQ-A-------DPQVVQGYLNETKLLAKLQGN-VCVVALYDYQLVRE-
TTK_Mmus         K-KQINAIKYVNLEDA-------DSQTIESYRNEIAFLNKLQQHSDKIIRLYDYEIT---
TtkA_Ddis        D-LKIYALKYVCLS---------DPNEIEAQLNEIEMLKRLRKQ-VNIIQLIDYEVNMA-
TTK_Spur         DSKKLWALKYVKLDFA-------DEMAMQSYMNEITLLARLKTF-KRIIHLHDYELT---
CC1G_03033_Ccin  A-NELYAIKRVSLDKT-------DAETMSGYMNEIALLKRLEGN-SRIIRLIDSEVKPGP
TTK_a_Smoe       D-CTIYALKRIILKGR-------DHQTACGFHQEIEYLERLKGK-NHIIQLIDYEVTDKT
TTK_b_Smoe       D-CTIYGLKRIILKGR-------DHQTACGFHQEIEYLERLKGK-NHIIQLIDYEVTDKT
GK068_Glam       S-GKLCAIKLLWSQKGNNYNEKEEKTNYKAMIDEIEIMKRLKGK-GICLDLVDCQVVTKH
                       .:* :  .         :     .   *   : :*.      : * * ::

TTK_Hsap         ---------------DQYIYMVMECGNIDLNSWLKKKKS---------------IDPWER
MPS1_Scer        ----------------GLLYLIMECGDHDLSQILNQRSGM-P------------LDFNFV
CG7643_Dmel      ---------------ESKLYMVMEKGDCDLNKILQSYTTN--------------LPLYSL
TTK_Mmus         ---------------EQYIYMVMECGNIDLNSWLKKKKS---------------INPWER
TtkA_Ddis        ---------------KNYILLVLEFGEIDLSKLLQRLQTPNG------------TNVNFI
TTK_Spur         ---------------EDYIYLVMECGSIDLATFLKKNKDN--------------LSPHHM
CC1G_03033_Ccin  ------------GGSKGHLLLVMECGEIDLAKLLQEQMKE-P------------LNMVWV
TTK_a_Smoe       IFRSDSAAAHGEILNDVRIYMVLEYGEIDLARILERKKSEDGQ-----------LDENWL
TTK_b_Smoe       IFRSDSAATHGEILNDVRIYMVLEYGEIDLARILERKKSEDGQ-----------LDENWL
GK068_Glam       N----------P-FLRRYALIVMELGDTDLRSFMKEFKSVKRDRVVGPLHPCNLLPESKI
                                     :::* *. **   ::

TTK_Hsap         KSYW-----------------KNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGI
MPS1_Scer        RFYT-----------------KEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGI
CG7643_Dmel      MNIL-----------------YQMLQAVNYIHQHGVIHSDLKPANFLMVSGRLKLIDFGI
TTK_Mmus         KSYW-----------------KNMLEAVHIIHQHGIVHSDLKPANFVIVDGMLKLIDFGI
TtkA_Ddis        RIYW-----------------QQMLQAVHTIHEEKIIHGDLKPANFVSVQGSLKLIDFGI
TTK_Spur         WCYW-----------------QEMLEAVDVIHKEGIVHSDLKPANFIFVEASLKLIDFGI
CC1G_03033_Ccin  SYYW-----------------QQMLQAVHVIHEEKIVHSDLKPANFVLVKGQLKLIDFGI
TTK_a_Smoe       RLHW-----------------EHILKAVNTIHEERIVHADLKPANFLLVQGALKLIDFGI
TTK_b_Smoe       RLHWEVKHSSSSSSFKLVFHSQHILKAVNTIHEERIVHADLKPANFLLVQGALKLIDFGI
GK068_Glam       LSLL-----------------YDMITVLHRMHMQGYIHCDLKPQNFMFYKGRLRLIDFGI
                                       .::  :. :*    :* **** **:  .. *::*****

TTK_Hsap         ANQMQP-DTTSVVKDSQVGTVNYMPPEAIKDMSSSR-----ENGKSKSKISPKSDVWSLG
MPS1_Scer        ANAVPE-HTVNIYRETQIGTPNYMAPEALVAMNYTQN-SENQHEGNKWKVGRPSDMWSCG
CG7643_Dmel      ASNIAV-DSTSIIKFSQAGTFNYISPEALTDTSTGNSP-MRRADQPKIKISTKSDVWSLG
TTK_Mmus         ANQMQP-DTTSIVKDSQVGTVNYMAPEAIRDMSSSR-----ENSKIRTKVSPRSDVWSLG
TtkA_Ddis        AKAIQSDDTTNIVRESQIGTINYISPEALIDTSQG-------GPKQCMKLGRASDIWSLG
TTK_Spur         ANAIQN-DHTSVVKESQVGTLNYMSPEAIQDTSPVNEVNEYGHKKPRLKINCKSDVWSLG
CC1G_03033_Ccin  ANAIAN-DTTNIQRDHQIGTVNYMSPEAIELPD----------GMRRLKVGRPSDVWSLG
TTK_a_Smoe       AKAIQN-DTTNIVRESQVGTLNYMSPEAFLMNSR--------DEQGTVKCGRASDIWSLG
TTK_b_Smoe       AKAIQN-DTTNIVRESQVGTLNYMSPEAFLMNSR--------DEQGTVKCGRASDIWSLG
GK068_Glam       SKAMQQ-DTTCAVTDTIAGTPKYMAPEIMLTIGRT-------MDNKKTELHRVADVWSIG
                 :. :   . .        ** :*:.** :   .               :    :*:** *

TTK_Hsap         CILYYMTYGKTPFQQI--------------------------------------------
MPS1_Scer        CIIYQMIYGKPPYGSF--------------------------------------------
CG7643_Dmel      CILYLLLYQKTPFGHI--------------------------------------------
TTK_Mmus         CILYYMTYGRTPFQHI--------------------------------------------
TtkA_Ddis        CILYEMAFGYPPFKSF--------------------------------------------
TTK_Spur         CILYSMVYGRTPFQHIVHRLLKMQAICNPDHFIDFQPIENELLLDVMKINCKSDVWSLGC
CC1G_03033_Ccin  IILYQMVYGHPPFQHL--------------------------------------------
TTK_a_Smoe       CILYQMVYGRTPFSHL--------------------------------------------
TTK_b_Smoe       CILYQMVYGRTPFSHL--------------------------------------------
GK068_Glam       CILFEMAAGYHPLDRYVDN-----------------------------------------
                  *:: :     *

TTK_Hsap         ---------------INQISKLHAIIDPNHEIEFPDIP----------------------
MPS1_Scer        ---------------Q-GQNRLLAIMNPDVKIPFPEHTSNNE------------------
CG7643_Dmel      ---------------RNVYAKMSAITTPGTSIEYPAIPPY--------------------
TTK_Mmus         ---------------INQVSKLHAIINPAHEIEFPEIS----------------------
TtkA_Ddis        ---------------SNIISKYQAIINPHHKIEFPVHP----------------------
TTK_Spur         ILYSMVYGRTPFQHIVHRLLKMQAICNPDHFIDFQPIE----------------------
CC1G_03033_Ccin  ---------------S-VYQKMKAIPDLSHVIEYPEYTVPSIPAKTSSNGTVEPPKRLEH
TTK_a_Smoe       ---------------S-FYQKIREITNENHVINFPPVS----------------------
TTK_b_Smoe       ---------------S-FYQKIREITNENHVINFPPVS----------------------
GK068_Glam       ----------------HPLALLNTVAEKRYVIEADDLH----------------------
                                         :      *

TTK_Hsap         -----EKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPV---N---QMAKGTTEEM
MPS1_Scer        ---KIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGS------I---------
CG7643_Dmel      ----YPIMLVHMAKNCLQLNPKKRPSCTELLQYPFHMIIPLQN---L---QI--------
TTK_Mmus         -----EKDLRDVLKCCLVRNPKERISIPELLTHPYVQIQPHPG---S---QMARGATDEM
TtkA_Ddis        -----NENLLKVLKLCLIRNPHERPTIPTLLNHDFLK-----------------------
TTK_Spur         -----NELLLDVMKKCLTRDVKRRPSIEELLNHPYVKKPFPAAE--K---STASLTTEHI
CC1G_03033_Ccin  LKRRVRADVIRGIKSCLCRNPKERATIPELLEQPWLGLTGNEPEPVRPRIEDMLGEKETL
TTK_a_Smoe       -----NPLIVDVMKSCLMWDKDKRPRIPQLLEHAFLKPRPPPPP------DDHHYLREAL
TTK_b_Smoe       -----NPLIVDVMKSCLMWDKDKRPRIPQLLEHAFLKPRPPPPS------DDHHYLREAL
GK068_Glam       ----VSPELRELILLCLEHSPKDRITMEGIFAHACLKNQFSQN-------E---------
                                **  . . *     ::

TTK_Hsap         KYVLGQLV--GLNSPNSILK-------AAKTLYEHYSGGESHNSSS--------------
MPS1_Scer        ------------------------MEDLIRNAVRYGSEKPHISQDDLNDVVD--------
CG7643_Dmel      ------------------------------------------------------------
TTK_Mmus         KYVLGQLV--GLNSPNSILK-------TAKTLYERYNCGEGQDSSS--------------
TtkA_Ddis        ------------------------------------------------------------
TTK_Spur         SALVSQLSQSQINSPRSIAR-------LAQGVVEQISRGQQIDISS-----AVKGNAQQQ
CC1G_03033_Ccin  ---IN---------PYYMAQ-------LMQYCVKLAREDKPMDAET-L-QKD--------
TTK_a_Smoe       ---LESF------QAYVSARGSMELTELIRKAIK-----PPLDG--GHEMLD--------
TTK_b_Smoe       ---LESF------QAYVLARGSMELTELIRKAIK-----PPLDG--GHEKLD--------
GK068_Glam       ------------------------------------------------------------


TTK_Hsap         ------------------------------------------------------------
MPS1_Scer        ------------------------------------------------------------
CG7643_Dmel      ------------------------------------------------------------
TTK_Mmus         ------------------------------------------------------------
TtkA_Ddis        ------------------------------------------------------------
TTK_Spur         QIPQAPSQYQYPHQPHPQPHAHQHQHHHQQGQVSGHDGGYRSQQRAPLRVINSSDMASHH
CC1G_03033_Ccin  ------------------------------------------------------------
TTK_a_Smoe       ------------------------------------------------------------
TTK_b_Smoe       ------------------------------------------------------------
GK068_Glam       ------------------------------------------------------------


TTK_Hsap         --------------SKTF-----------EKKRGKK
MPS1_Scer        TVLRKF-------------------------ADYKI
CG7643_Dmel      -----------------P-----------SRTANSN
TTK_Mmus         --------------SKTF-----------DKKRERK
TtkA_Ddis        -----------------------------------I
TTK_Spur         SLLKPLSLAPKYDISSSQ-----------ENGQMNT
CC1G_03033_Ccin  AEV-----------RELV-----------VPMLADN
TTK_a_Smoe       EVLLPF--------ARLYVKRAGKAALCELLTSVTM
TTK_b_Smoe       EVLLPF--------ARLYVKRVGKAALCELLTSVTM
GK068_Glam       -----------------------------VSEFQRS