Protein (view, download) , Domain (view, download)
SNF1A_Dmel       MPQM-----------RAAAAE---------------------------------------
AMPKa2_Mmus      MAEK--------------------------------------------------------
AMPKa1_Mmus      MRRL-----------SSWRKM---------------------------------------
SNF1_Scer        MSSN-----------NNTNTA---------------------------------------
AMPKa2_Hsap      MAEK--------------------------------------------------------
AMPKa1_Hsap      MRRL-----------SSWRKM---------------------------------------
T01C8.1_Cele     MFSH-----------QDRDRDRKEDGGGDGTEMKSKSRSQPSGLNRVKNLSRKLSAKSRK
Snf1_Ddis        MSSY-----------QQNPIG---------------------------------------
1110_Tthe        MVQQ-----------NESATE---------------------------------------
11543_Tthe       MAEP-----------DAPKAA---------------------------------------
20428_Tthe       MTST-----------NSG------------------------------------------
21336_Tthe       MSNK-----------QNIDKH---------------------------------------
26498_Tthe       MNQA-----------PE-------------------------------------------
4451_Tthe        MSQV-----------RQNMQG---------------------------------------
7432_Tthe        MQQT-----------EQQHKQ---------------------------------------
27742_Tthe       MSQV-----------QQQAQS---------------------------------------
AMPK_Spur        MTTI--------------------------------------------------------
aak-1_Cele       MPPS-----------GRFDRT---------------------------------------
CC1G_10117_Ccin  MDES--------------------------------------------------------
AqueK057_Aque    MDSI-----------ME-------------------------------------------
AMPK_f_Smoe      MRFNLILTWGGFSSGMDRPIV---------------------------------------
AMPK_e_Smoe      MSSR-----------G--------------------------------------------
AMPK_a_Smoe      MDGK--------------------------------------------------------
AMPK_d_Smoe      MDGK-----------A--------------------------------------------
AMPK_b-1_Smoe    MDQQ-----------QEQQ-----------------------------------------
AMPK_b-2_Smoe    MDQQ-----------QQQQ-----------------------------------------
AMPK_c_Smoe      FSSG-----------MDRPIV---------------------------------------
GK014_Glam       MSDQ--------------------------------------------------------
GK013_Glam       MSST-----------TTG------------------------------------------
GK015_Glam       MPKT-----------DKVADR---------------------------------------
                 :

SNF1A_Dmel       --------------------A----------------------VA---------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      --------------------A----------------------T----------------
SNF1_Scer        --------------------P----------------------ANANSSHHHHHHHHHHH
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      --------------------A----------------------T----------------
T01C8.1_Cele     ERKDRDSTDNSSKMSSPGGET----------------------ST---------------
Snf1_Ddis        --------------------S----------------------FGGLY------------
1110_Tthe        --------------------K----------------------STN--------------
11543_Tthe       --------------------S-EQQNQNGAKGESNAAVRGQSNSQH--------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       --------------------D-DQR------------VPS--QQDS--------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        ------------------------------------------------------------
7432_Tthe        --------------------N-QQRH-----------QLS--LSNS--------------
27742_Tthe       --------------------Q----------------------SNS--------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       --------------------I---------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      --------------------A---------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      --------------------A---------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       --------------------AVDDA------------CPPD-ASRE--------------


SNF1A_Dmel       ------------AG--------------------------------------------SA
AMPKa2_Mmus      -----------------------------------------------------------Q
AMPKa1_Mmus      ------------AE--------------------------------------------KQ
SNF1_Scer        HHGHGGSNSTLNNP--------------------------------------------KS
AMPKa2_Hsap      -----------------------------------------------------------Q
AMPKa1_Hsap      ------------AE--------------------------------------------KQ
T01C8.1_Cele     ------------KQ--------------------------------------------QQ
Snf1_Ddis        ------------GS--------------------------------------------GG
1110_Tthe        ------------NNNVVLPLEENRERQNQTTQSTKNNESINANGIKIENPLIKNGIPVVP
11543_Tthe       ------------NN--------------------------------------------HH
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------QQ---------------------------------------------H
26498_Tthe       ------------------------------------------------------------
4451_Tthe        -----------------------------------------------------------S
7432_Tthe        ------------PT--------------------------------------------NR
27742_Tthe       ------------QQ--------------------------------------------LN
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ----------------------------------------------------------AL
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    -----------------------------------------------------------G
AMPK_f_Smoe      ----------------------------------------------------------RN
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ----------------------------------------------------------RN
GK014_Glam       ------------------------------------------------------------
GK013_Glam       -------------S--------------------------------------------ST
GK015_Glam       ------------DQ--------------------------------------------DT


SNF1A_Dmel       NGQPLVKIGHYLL-----------------------------------------------
AMPKa2_Mmus      KHDGRVKIGHYVL-----------------------------------------------
AMPKa1_Mmus      KHDGRVKIGHYIL-----------------------------------------------
SNF1_Scer        SLADGAHIGNYQI-----------------------------------------------
AMPKa2_Hsap      KHDGRVKIGHYVL-----------------------------------------------
AMPKa1_Hsap      KHDGRVKIGHYIL-----------------------------------------------
T01C8.1_Cele     ELKAQIKIGHYIL-----------------------------------------------
Snf1_Ddis        IEKSSQIIGNYRL-----------------------------------------------
1110_Tthe        EDKKSKSIGHYIL-----------------------------------------------
11543_Tthe       QAHSIVTVGNFEI-----------------------------------------------
20428_Tthe       ---NTLKIEHYLV-----------------------------------------------
21336_Tthe       QKNQDQKTPAQIT-----------------------------------------------
26498_Tthe       --GYFAIIGNYYV-----------------------------------------------
4451_Tthe        QVEKEKTVGHYII-----------------------------------------------
7432_Tthe        DSQQIKQIGNYILSKFLVKFQLSQNTNTNYLYQCKLQSIHRSIDIFYRIFYQMHFTHKFQ
27742_Tthe       SIKKSKQLGNYVL-----------------------------------------------
AMPK_Spur        --NSGVKIGHYVL-----------------------------------------------
aak-1_Cele       AGTGHLKIGNFVI-----------------------------------------------
CC1G_10117_Ccin  QMFPPSKLGEYTV-----------------------------------------------
AqueK057_Aque    KTPQKLKIGRYIL-----------------------------------------------
AMPK_f_Smoe      FAARADLELRYRT-----------------------------------------------
AMPK_e_Smoe      -----SCSI---------------------------------------------------
AMPK_a_Smoe      ----ANDFLNYKM-----------------------------------------------
AMPK_d_Smoe      -----NDFLNYKM-----------------------------------------------
AMPK_b-1_Smoe    -SARRTEFLHYKL-----------------------------------------------
AMPK_b-2_Smoe    -SARRTEFLHYKL-----------------------------------------------
AMPK_c_Smoe      FAARADLELRYRT-----------------------------------------------
GK014_Glam       -----EIIGDYLL-----------------------------------------------
GK013_Glam       VRVRVKRVSNYIT-----------------------------------------------
GK015_Glam       KKIRVKRVGNYII-----------------------------------------------


SNF1A_Dmel       ----GATLGTGTFGKVK-------------------------------------------
AMPKa2_Mmus      ----GDTLGVGTFGKVK-------------------------------------------
AMPKa1_Mmus      ----GDTLGVGTFGKVK-------------------------------------------
SNF1_Scer        ----VKTLGEGSFGKVK-------------------------------------------
AMPKa2_Hsap      ----GDTLGVGTFGKVK-------------------------------------------
AMPKa1_Hsap      ----GDTLGVGTFGKVK-------------------------------------------
T01C8.1_Cele     ----KETLGVGTFGKVK-------------------------------------------
Snf1_Ddis        ----DKTLGIGSFGKVK-------------------------------------------
1110_Tthe        ----GKKLGEGTFGKVK-------------------------------------------
11543_Tthe       ----GQTIGRGTFGKVK-------------------------------------------
20428_Tthe       ----GKTLGCGASGKVKREQFRLFKLTFFRGVQFTLLINQSSLSSENAKIFSKKSEFKNI
21336_Tthe       ----SETLGEGTFGKVK-------------------------------------------
26498_Tthe       ----GKTIGRGTFGKVK-------------------------------------------
4451_Tthe        ----GQNIGEGTFGKVK-------------------------------------------
7432_Tthe        KNISDKTIGRGTFGKVK-------------------------------------------
27742_Tthe       ----IKTLGEGAFGKVK-------------------------------------------
AMPK_Spur        ----GETIGMGTFGKVK-------------------------------------------
aak-1_Cele       ----KETIGKGAFGAVK-------------------------------------------
CC1G_10117_Ccin  ----IADIAEGTFGKVK-------------------------------------------
AqueK057_Aque    ----GETLGTGTFGKVK-------------------------------------------
AMPK_f_Smoe      ----ERRIGTGSFSTVV-------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ----GKTLGIGSFGKVK-------------------------------------------
AMPK_d_Smoe      ----GKTLGIGSFGKVK-------------------------------------------
AMPK_b-1_Smoe    ----GKTLGIGSFGKVK-------------------------------------------
AMPK_b-2_Smoe    ----GKTLGIGSFGKVK-------------------------------------------
AMPK_c_Smoe      ----ERRIGTGSFSTVI-------------------------------------------
GK014_Glam       ----GRQLGTGTFGKVR-------------------------------------------
GK013_Glam       ----GKSLGVGTFGDVR-------------------------------------------
GK015_Glam       ----GKTIGEGSFSKVR-------------------------------------------


SNF1A_Dmel       -----IGEHQITR-------------------------------VKVA-----------V
AMPKa2_Mmus      -----IGEHQLTG-------------------------------HKVA-----------V
AMPKa1_Mmus      -----VGKHELTG-------------------------------HKVA-----------V
SNF1_Scer        -----LAYHTTTG-------------------------------QKVA-----------L
AMPKa2_Hsap      -----IGEHQLTG-------------------------------HKVA-----------V
AMPKa1_Hsap      -----VGKHELTG-------------------------------HKVA-----------V
T01C8.1_Cele     -----VGIHETTQ-------------------------------YKVA-----------V
Snf1_Ddis        -----LAEHIRTG-------------------------------VKVA-----------I
1110_Tthe        -----LATHILTG-------------------------------EKVA-----------I
11543_Tthe       -----LGIHKITN-------------------------------EKVA-----------V
20428_Tthe       FCFIIVAKHDITG-------------------------------KEVA-----------I
21336_Tthe       -----VATHILTG-------------------------------EKVA-----------I
26498_Tthe       -----MGLHTYTMENIQLTFFTQVSINISKDNKQTLQLILNNENNKVA-----------I
4451_Tthe        -----LGTHIETR-------------------------------EKVA-----------I
7432_Tthe        -----LGVHTLTN-------------------------------EKVNIFSVNLSTAQTI
27742_Tthe       -----LATHILTG-------------------------------EYVA-----------I
AMPK_Spur        -----MGEHLLTQ-------------------------------HKVA-----------I
aak-1_Cele       -----RGTHIQTG-------------------------------YDVA-----------I
CC1G_10117_Ccin  -----MAIHTVTG-------------------------------HKVA-----------M
AqueK057_Aque    -----IADHDLTG-------------------------------HKVA-----------V
AMPK_f_Smoe      -----LGEHRRSA-------------------------------RRVA-----------I
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      -----VAEHIPTG-------------------------------HKVA-----------I
AMPK_d_Smoe      -----VAEHIPTG-------------------------------HKVA-----------I
AMPK_b-1_Smoe    -----IGEHVLTG-------------------------------HKVA-----------I
AMPK_b-2_Smoe    -----IGEHVLTG-------------------------------HKVA-----------I
AMPK_c_Smoe      -----LGEHRRSA-------------------------------RRVA-----------I
GK014_Glam       -----VATHIPTN-------------------------------CTVA-----------I
GK013_Glam       -----LATHLITG-------------------------------ERVA-----------L
GK015_Glam       -----LGTHVLTN-------------------------------ERIA-----------L


SNF1A_Dmel       KILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQ-----------------------
AMPKa2_Mmus      KILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ-----------------------
AMPKa1_Mmus      KILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ-----------------------
SNF1_Scer        KIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYD-----------------------
AMPKa2_Hsap      KILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQ-----------------------
AMPKa1_Hsap      KILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQ-----------------------
T01C8.1_Cele     KILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLYQ-----------------------
Snf1_Ddis        KILNRTKIKNLKMDEKIRREIQNMKLFRHPHIIKLYE-----------------------
1110_Tthe        KILEKDRIIDVSDVERVSREIHILKLLRHSNIIQLYE-----------------------
11543_Tthe       KVLDKDKLIDSADKKRLQREISILRKIRHPNIIQLYE-----------------------
20428_Tthe       KIINKKKMTVKKMSNKIKREIRLLRFFNHQNIIRLYE-----------------------
21336_Tthe       KILEKEKIQDVSDVERVSREIHILKLLRHQNIIQLYE-----------------------
26498_Tthe       KILDKDKIVDESDKIRVAREIQILRKIRHPNIIQLYEVNFQNLYFGIIQQFEQFIKYQDQ
4451_Tthe        KILEKDKITEQADVERVAREIHILKILRHPNIIQLYE-----------------------
7432_Tthe        KILEKRMIQGDQDMLSVQSEISILKSVNHPNISQLYQ-----------------------
27742_Tthe       KILEKKKIIDVTDVERVQRELHILKMIRHPSLIQLYE-----------------------
AMPK_Spur        KILNRQKIKNLDVVSKIKREIQNMKLFRHPHIVKLYQ-----------------------
aak-1_Cele       KILNRGRMKGLGTVNKTRNEIDNLQKLTHPHITRLFR-----------------------
CC1G_10117_Ccin  KYISKAVIQREKTKTRVRREFEYLRTLRHPHIIKLYE-----------------------
AqueK057_Aque    KILNRNKIQHLDVADKITREIQILKLFRHPHIIKLYE-----------------------
AMPK_f_Smoe      KVMSRRNIIEGGMREKVAREVRTMALLRHPHIVRLYE-----------------------
AMPK_e_Smoe      -ILSRRGASRRTKPG---------------------------------------------
AMPK_a_Smoe      KILNRRKIKAMDMEEKVRREIKILRLFMHPHIIRLYE-----------------------
AMPK_d_Smoe      KILNRRKIKAMDMEEKVRREIKILRLFMHPHIIRLYE-----------------------
AMPK_b-1_Smoe    KILNRRKIRAMDMEEKVRREIKILRLFMHPHIIRLYE-----------------------
AMPK_b-2_Smoe    KILNRRKIRAMDMEEKVRREIKILRLFMHPHIIRLYE-----------------------
AMPK_c_Smoe      KVMSRRNIIEGGMREKVAREVRTMALLRHPHIVRLYE-----------------------
GK014_Glam       KILSKSKITQMNMWSKVEREIMIMKMARHPHIINLYE-----------------------
GK013_Glam       KVLDKSRIQCEDDFKRIVREIQVLKLLDHSNIVRLLE-----------------------
GK015_Glam       KIIEKSKITEAADIERITREIQILKLLNHPNVIKLYE-----------------------
                   :.:

SNF1A_Dmel       ---------VISTPSDIFMIMEYVSGGELFDYIV--K----------HGK----------
AMPKa2_Mmus      ---------VISTPTDFFMVMEYVSGGELFDYIC--K----------HGR----------
AMPKa1_Mmus      ---------VISTPSDIFMVMEYVSGGELFDYIC--K----------NGR----------
SNF1_Scer        ---------VIKSKDEIIMVIEYA-GNELFDYIV--Q----------RDK----------
AMPKa2_Hsap      ---------VISTPTDFFMVMEYVSGGELFDYIC--K----------HGR----------
AMPKa1_Hsap      ---------VISTPSDIFMVMEYVSGGELFDYIC--K----------NGRKSDVPGVVKT
T01C8.1_Cele     ---------VISTPSDIFMIMEHVSGGELFDYIV--K----------HGR----------
Snf1_Ddis        ---------VIETTTDIFMVMEYVTGGELFEYIV--K----------NGK----------
1110_Tthe        ---------IIETPKQLFLIMEYASGGELFDYIV--A----------NQR----------
11543_Tthe       ---------IIETPRQLYLFMEYAPNGELFDYIV--K----------RTR----------
20428_Tthe       ---------VLDTNTDIFVVTEYISGGDLYDVIA--S----------KGK----------
21336_Tthe       ---------IIETEKQLFLITEYASGGELFDYIV--K----------NTK----------
26498_Tthe       IVFNLLLKQIIESQTQLFLITEYAPNNELFDFIV--KRNSQLFIKNKHNR----------
4451_Tthe        ---------IIETQKQLYLIMEYAQGGELFDYIV--K----------NQK----------
7432_Tthe        ---------IIETNDCLYLVLEYAQNGELFDFIV--R----------KRR----------
27742_Tthe       ---------IIETPTHIFLVMEYCSKGEVFGYIQ--Q----------KQR----------
AMPK_Spur        ---------VISTPTDIFMVMEYVAGGELFDYIV--K----------HGK----------
aak-1_Cele       ---------VISTPSDIFLVMELVSGGELFSYIT--R----------KGA----------
CC1G_10117_Ccin  ---------VISTPTDIIFVLEYA-GGELFNYIV--A----------NGR----------
AqueK057_Aque    ---------VITTPKDIFMVMEYVSGGELFEYIV--K----------HGK----------
AMPK_f_Smoe      ---------VFETPRDVLIVMEYAERGDLYEYLLVQR----------NQR----------
AMPK_e_Smoe      ------------VSSSRFVLLRLV------------K----------KTE----------
AMPK_a_Smoe      ---------VVETMNDIFVVMEYVKSGELFDYIV--E----------KGR----------
AMPK_d_Smoe      ---------VVETANDIFVVMEYVKSGELFDYIV--E----------KGR----------
AMPK_b-1_Smoe    ---------VVETSTDIFVVMEFVKSGELFDYIV--E----------NGR----------
AMPK_b-2_Smoe    ---------VVETSTDIFVVMEFVKSGELFDYIV--E----------NGR----------
AMPK_c_Smoe      ---------VFETPRDVLIVMEYAERGDLYEYLLVQR----------NQR----------
GK014_Glam       ---------VIYREDDIYLVMEYAEGGELFSYIV--K----------HKR----------
GK013_Glam       ---------VIDTPRHIYLVTEYVDNGELFNYVV--Q----------KQK----------
GK015_Glam       ---------IVDTPRHVYIVQEYMNNGELFDYIV--A----------KGR----------
                                   .. .                         .

SNF1A_Dmel       -----LQEH-QARRFFQQIISGVDYCHR-HMIVHRDLKPENLLLDH-NMHVKIADFGLSN
AMPKa2_Mmus      -----VEEV-EARRLFQQILSAVDYCHR-HMVVHRDLKPENVLLDA-QMNAKIADFGLSN
AMPKa1_Mmus      -----LDEK-ESRRLFQQILSGVDYCHR-HMVVHRDLKPENVLLDA-HMNAKIADFGLSN
SNF1_Scer        -----MSEQ-EARRFFQQIISAVEYCHR-HKIVHRDLKPENLLLDE-HLNVKIADFGLSN
AMPKa2_Hsap      -----VEEM-EARRLFQQILSAVDYCHR-HMVVHRDLKPENVLLDA-HMNAKIADFGLSN
AMPKa1_Hsap      GSTKELDEK-ESRRLFQQILSGVDYCHR-HMVVHRDLKPENVLLDA-HMNAKIADFGLSN
T01C8.1_Cele     -----LKTA-EARRFFQQIISGVDYCHR-HMVVHRDLKPENLLLDE-QNNVKIADFGLSN
Snf1_Ddis        -----LLED-ESRRLFQQMISGVDYCHH-HMVVHRDLKPENLLLDPINKCIKIADFGLSN
1110_Tthe        -----VKER-EAARFFQQIISGIEYIHK-LNIVHRDMKPENLLLNH-DKSIKIVDFGLSN
11543_Tthe       -----LSER-QASKFLQQIINGIEYMSK-IGVVHRDLKPENLLLDH-NYNIKIVDFGLSN
20428_Tthe       -----LPEQ-EAKRYFKQIVAGVDYCHR-NLVAHRDLKLENILIDD-NNNIKIADFGLSN
21336_Tthe       -----VQER-EASVFFQQIISGVEYIHK-LKIVHRDMKPENLLLSY-NKRIKIVDFGLSN
26498_Tthe       -----LNER-QSARFLLQILSAVEYLHQ-NNIVHRDLKPENLLLDC-NNNIKVVDFGLSN
4451_Tthe        -----INER-ESCKYIQQILSGVEYLHN-LNIAHRDLKPENLLLDH-QKNIKIVDFGLSN
7432_Tthe        -----LTEQ-ETCLVFAQILNALEYLHD-LGISHRDLKPENLLFDY-KYELKLVDFGLSK
27742_Tthe       -----LDEV-EASKFYQEILYGIEYLHK-LQVVHRDLKPENLLLDI-NHNIKIVDFGLSN
AMPK_Spur        -----LKEH-EARRFFQQIISGVDYCHR-HMIVHRDLKPENLLLDP-NLHVKIADFGLSN
aak-1_Cele       -----LPIR-ESRRYFQQIISGVSYCHN-HMIVHRDLKPENLLLDA-NKNIKIADFGLSN
CC1G_10117_Ccin  -----MSEA-QARRFFQQIISGIEYSHR-LKIVHRDLKPENVLLDD-DLNVKIADFGLSN
AqueK057_Aque    -----SSEN-ESRAFFQQIISGVDYCHR-HKVVHRDLKPENLLLDS-NNKVKIADFGLSN
AMPK_f_Smoe      -----LEEA-EARWFFQQLIAGVEYCHG-KSAIHRDIKVENLFLDS-QRHIKIGDFGLCN
AMPK_e_Smoe      -----YNSHTSPDHFWSGIL------SQ-KYGGHRDLKPENLLLDS-RCNVKIADFGLSN
AMPK_a_Smoe      -----LQED-EARRFNINMI----------------------------------------
AMPK_d_Smoe      -----LQED-EARRFFQQIISGVEYCHR-NMVVHRDLKPENLLLDS-RCNVKIADFGLSN
AMPK_b-1_Smoe    -----LQED-EARCFFQQIISGVEYCHR-NMVVHRDLKPENLLLGS-KCSVKIADFGLSN
AMPK_b-2_Smoe    -----LQED-EARCFFQQIISGVEYCHR-NMVVHRDLKPENLLLGS-KCSVKIADFGLSN
AMPK_c_Smoe      -----LEEA-EARWFFQQLITGVEYCHS-KSAIHRDIKVENLFLDS-QRHIKIGDFGLCN
GK014_Glam       -----LDST-TARKFFQQIISALSYLHIKVSVTHRDLKPENILLTK-NKLIKLSDFGLSN
GK013_Glam       -----LSEE-EACKYFHQIVSALSYCHS-RKVCHRDMKLENVLLDS-SYNIKLIDFGLSN
GK015_Glam       -----LSEK-EACRFLCQLLNGLHFLHS-RRIVHRDLKPENLLLTA-NNDIKIIDFGLSN
                            .      ::

SNF1A_Dmel       M-MLDG-EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVP
AMPKa2_Mmus      M-MSDG-EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVP
AMPKa1_Mmus      M-MSDG-EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVP
SNF1_Scer        I-MTDG-NFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIP
AMPKa2_Hsap      M-MSDG-EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVP
AMPKa1_Hsap      M-MSDG-EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVP
T01C8.1_Cele     I-MTDG-DFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEHVP
Snf1_Ddis        M-MQDG-DFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYAFLCAKLPFDDESIP
1110_Tthe        T-YKKN-ELLKTACGSPCYAAPEMITGKRYNGLGVDIWSCGVILFALICGYLPFEDPVTA
11543_Tthe       T-YKDN-EKLKTACGSPCYAAPEMVAGKPYNGLQTDIWSSGVILYAMLCGYLPFEDQNTS
20428_Tthe       I-MNDG-KYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEEVIP
21336_Tthe       T-YKKN-ELLKTACGSPCYAAPEMIAGKRYLGLGVDIWSCGVILFALVCGYLPFEDPNTS
26498_Tthe       M-YEDG-QTLKTACGSPCYAAPEMVSGKRYEGLKTDIWSCGIILYAMLCGYLPFEDSNTT
4451_Tthe        L-YKEG-ELLKTACGSPCYAAPEMIQGKKYEGLCVDIWSTGIIMFALICGYLPFEDQNTS
7432_Tthe        I-CQEADQQLYTCCGSPCYASPETISSQPYVGRYVDLWSCGIILFAMLCGYLPFDDDNQA
27742_Tthe       M-YKKN-ELLKTACGSPCYAAPEMIEGKKYESPQVDIWSSGVILFALLCGYLPFEDEDTR
AMPK_Spur        M-MTDG-EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVP
aak-1_Cele       Y-MTDG-DLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVP
CC1G_10117_Ccin  E-ISDG-DFLTTSCGSPNYAAPEVIRGGVYAGPEIDVWSSGVILYVMLCGRLPFEDDDVQ
AqueK057_Aque    L-MKDG-EFLRTSCGSPNYAAPEVVSGKLYAGPEVDVWSCGIILYALLCGSLPFEDTNIS
AMPK_f_Smoe      T-MQEG-GFLRTSCGSTHYAAPELLLRRPYVGPEVDVWSCGVVLYVLLGGCYPFDDANTT
AMPK_e_Smoe      I-MRDG-HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGSLPFDDENIP
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      I-MRDG-HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGSLPFDDENIP
AMPK_b-1_Smoe    I-MRDG-HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGSLPFDDENIP
AMPK_b-2_Smoe    I-MRDG-HFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGSLPFDDENIP
AMPK_c_Smoe      T-MQEG-GFLRTSCGSTHYAAPELLLRRPYVGPEVDVWSCGVVLYVLLGGCYPFDDANTT
GK014_Glam       V-MSEG-EFLKTSCGSPNYASPEVVAGTLYIGPATDIWSAGCVLYTLLVGRLPFDDHYMP
GK013_Glam       ILMSDE-AKFKTACGSPSYASPEMLSGKKYHGPSIDVWAIGIILFAMICGHLPFDHDNTE
GK015_Glam       I-FHD--TFMKTCCGSPAYAPPEMIQGKLYSGPSADLWSTGIILYAMLCGCLPFEGSTTQ


SNF1A_Dmel       TLFRKIKSGIFPIPEYLNK-QVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAYLFP-
AMPKa2_Mmus      TLFKKIRGGVFYIPDYLNR-SVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFP-
AMPKa1_Mmus      TLFKKICDGIFYTPQYLNP-SVISLLKHMLQVDPMKRAAIKDIREHEWFKQDLPKYLFP-
SNF1_Scer        VLFKNISNGVYTLPKFLSP-GAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLP-
AMPKa2_Hsap      TLFKKIRGGVFYIPEYLNR-SVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFP-
AMPKa1_Hsap      TLFKKICDGIFYTPQYLNP-SVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFP-
T01C8.1_Cele     SLFRKIKSGVFPTPDFLER-PIVNLLHHMLCVDPMKRATIKDVIAHEWFQKDLPNYLFP-
Snf1_Ddis        MLFKKIREGVFSIPDFVSP-SCADLIKKMLVVDPVKRITIHEIRNHPWFQVKLPKYLSS-
1110_Tthe        NLYKKITAGDFTVPKNVSN-EARDLLKSILNTDPQKRFTIEEIRNHPWCNQYKLNK-TP-
11543_Tthe       VLYKKIMNQDPVLPSFLSS-NSKGILSGILTKDPEKRYNIQDIRLHPFCKEREPIL--Q-
20428_Tthe       ALYKKIKA-------FFSP-EAHDIIKRMLRPNPIERIKFHELRLHPWLRENVPFYVEI-
21336_Tthe       NLYKKILAGDYQIPKFVSS-EGRDLIKNILTTDPTKRFTISDIRKHPWFNQVKPNPMCE-
26498_Tthe       DLYKKIINDPVKLPKFLTD-RSKSILNGILEKNPEKRLTIEAIRKHDFCILNSNQPILK-
4451_Tthe        VLYKKIVSGEFSIPRWVST-EAKDLLNCILNTDPVKRYKINDIRNHKWYLLFKQNL----
7432_Tthe        SLFAKIISCEYYIPTDISP-EASYLIRGLLKKDPNQRLSIKDIKNSAFYQNYMQGTQVK-
27742_Tthe       KLYDKILKGKYGIPSHVSP-DAKDLIEKILTVDPEKRMKFDQIKAHKWFNLYKRSYTIP-
AMPK_Spur        TLFRKIKGGHFTIPDHIERSQVKSLIQHMLQVDPLKRATIKDIREHDWFRIDMPQYLFP-
aak-1_Cele       TLFAKIKSGRYTVPYSMEK-QAADLISTMLQVDPVKRADVKRIVNHSWFRIDLPYYLFP-
CC1G_10117_Ccin  MLFHKISQGQFHCPSYLSK-DAQSLINSMLVVDPVKRATITDIINHPFFKVDLPRYLTP-
AqueK057_Aque    MLFRKIKSGQFYIPHYISK-GASDLLTQMLQVNPVKRITLPQIKEHTWFTTELPQYLFP-
AMPK_f_Smoe      TLYTKILSGTFNFPLFVPD-GPRDLISRMLTVDPRARITVAEIKEHAWFRINIPPHLSM-
AMPK_e_Smoe      NLFKKIKTGLYTLPSHLSP-GAKDLIPRMLLVEPMKRMTIPEIRQHPWFQAHLPRYLAV-
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      NLFKKIKTGLYTLPSHLSP-GAKDLIPRMLLVEPMKRMTIPEIRQHPWFQAHLPRYLAV-
AMPK_b-1_Smoe    NLFKKIKGGIYTLPSHLSS-GAKDLIPRMLLVDPMKRMTVAEIREHPWFQVNLPRYLAV-
AMPK_b-2_Smoe    NLFKKIKGGIYTLPSHLSS-GAKDLIPRMLLVDPMKRMTVAEIREHPWFQVNLPRYLAV-
AMPK_c_Smoe      TLYSKILSGTFNFPLFVPD-GPRDLISRMLTVDPRARITVAEIKEHAWFRINIPPHLSM-
GK014_Glam       ALFRKIKTGEYVIPDYVDS-GAADMLRGMMTVDVDKRFTIDIIRAHPWFTVNLPKHLLI-
GK013_Glam       TLYKKIISGVFHIPDHVSP-EAADLISKILVVDPDKRITLDEITKHPWYIQCYTGPEEP-
GK015_Glam       SLYIKILSGEFSTPSYLSQ-GAKDVLKALLTVNPDDRVTIEELITYPWIQKNWALNHDGR


SNF1A_Dmel       ---SSI-E------------------------------QDSN-----VIDTYAVAEVC--
AMPKa2_Mmus      ---EDP-S------------------------------YDAN-----VIDDEAVKEVC--
AMPKa1_Mmus      ---EDP-S------------------------------YSST-----MIDDEALKEVC--
SNF1_Scer        -PDLKP-HPEEENENNDSKKDGS------S--------PDND-----EIDDNLVNILS--
AMPKa2_Hsap      ---EDP-S------------------------------YDAN-----VIDDEAVKEVC--
AMPKa1_Hsap      ---EDP-S------------------------------YSST-----MIDDEALKEVC--
T01C8.1_Cele     ---PIN-E------------------------------SEAS-----IVDIEAVREVT--
Snf1_Ddis        -PHTFL-S------------------------------KSIQ-----TINNSILNEMV--
1110_Tthe        -EGIIV-G------------------------------YNRI-----PVDMDILKQL---
11543_Tthe       --GIIV-G------------------------------VHEI-----PVDQNILKQLE--
20428_Tthe       -FNQNT-R------------------------------MESK-----KLNEDILRKL---
21336_Tthe       --GIIV-G------------------------------YNRI-----PIDFDIIQQL---
26498_Tthe       --GIIF-G------------------------------KDDI-----LVDPLILQIIK--
4451_Tthe        --------------------------------------SNGI-----YVNEAILQKL---
7432_Tthe        -PGIRL-G------------------------------IDFI-----YVDEAIIEKL---
27742_Tthe       -PGVIV-G------------------------------YNHM-----PIDYDIVKEL---
AMPK_Spur        ---QND--------------------------------FDDS-----IVDVDAVKEVC--
aak-1_Cele       ---ECE--------------------------------NESS-----IVDIDVVQSVAEK
CC1G_10117_Ccin  -LPPPP-GPVLGMLT-TLVAPPKQLDYEII--------DGLG-----RIEEDVVEQLAA-
AqueK057_Aque    ---LPG-L------------------------------TEHH-----QIDSAVLSEVC--
AMPK_f_Smoe      -RSYYS--TV--------------LCFRM------------------LIDMDVLARVTQ-
AMPK_e_Smoe      -PPLDT-V------------------------------EQAK-----RIDEDILREVT--
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -PPLDT-V------------------------------EQAK-----RIDEDILREVT--
AMPK_b-1_Smoe    -PPLDS-A------------------------------EQAK-----RIDEDIANEVA--
AMPK_b-2_Smoe    -PPLDS-A------------------------------EQAK-----RIDEDIANEVA--
AMPK_c_Smoe      -RSYYS--TV--------------LCFRMLVLEKESFPFFFS-----QIDMDVLARVTQ-
GK014_Glam       ---SFD--------------------------------SDPSDREEELRTTDQGQRIVDM
GK013_Glam       -NPE---L------------------------------KMSK-----VVDFRIIYTMV--
GK015_Glam       SEPILTELP-----------------------------EISS-----DLNFGILLQM---


SNF1A_Dmel       ---------------TKF------GVKETEVHNSLL---SGD---PHDQLAIAYHLIIDN
AMPKa2_Mmus      ---------------EKF------ECTESEVMNSLY---SGD---PQDQLAVAYHLIIDN
AMPKa1_Mmus      ---------------EKF------ECSEEEVLSCLY---NRN---HQDPLAVAYHLIIDN
SNF1_Scer        ---------------STM------GYEKDEIYESLE---SSEDTPAFNEIRDAYMLIKEN
AMPKa2_Hsap      ---------------EKF------ECTESEVMNSLY---SGD---PQDQLAVAYHLIIDN
AMPKa1_Hsap      ---------------EKF------ECSEEEVLSCLY---NRN---HQDPLAVAYHLIIDN
T01C8.1_Cele     ---------------ERY------HVAEEEVTSALL---GDD---PHHHLSIAYNLIVDN
Snf1_Ddis        ---------------QVY-----APIDRERIIEELQ---KSG---EVNDLIVSYHLLVDS
1110_Tthe        ---------------ESF------SFNLDYAQKCID---A-N---KHNHVTTCYYLLLKK
11543_Tthe       ----------------KY------QINVEQAEDMVK---R-N---KHNNITSVYNLLLLK
20428_Tthe       ---------------AQMKNVNFHNLNEQTIRDAVI---K-R---DDYSFVIAYDLLLDD
21336_Tthe       ---------------EKF------NIDKEFAKNCVE---A-N---KHNHITTSYYLLLRK
26498_Tthe       ---------------NQY------GIDSEQARVMIQ---N-N---KHNQITATYYLLLNS
4451_Tthe        ---------------KDF------NIDLDVARKCIE---S-N---KHNDITTTYYLLLNK
7432_Tthe        ---------------SLF------GIEPSQARQSII---Q-N---HHNSITATYYLLKIK
27742_Tthe       ---------------EQQ------GIDREELIKSLD---A-N---NHNNITTSYYLLLKK
AMPK_Spur        ---------------EKF------NVREGEVQNALM---CGD---PHDQLRIAYYLIIDN
aak-1_Cele       TPPEKIIYFFIFRHFLKF------DVKEEDVTGALL---AED---HHHFLCIAYRLEVNH
CC1G_10117_Ccin  ---------------RMI------GVSKDDIWECLR---RDDGA-QGNAVKVAYMLLRDK
AqueK057_Aque    ---------------QKL------SVKREEVLQALR---SGD---RGHHLAVAYELVQDN
AMPK_f_Smoe      -----------------L------GFERQLLIMDLL---NNESS---E------------
AMPK_e_Smoe      ---------------K-L------GFDRNLLVDSLR---T-R---VANTATVTYYLMLDN
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ---------------K-L------GFDRNLLVDSLR---T-R---VANTATVTYYLMLDN
AMPK_b-1_Smoe    ---------------R-L------GFEKGQLIDSLR---N-R---VQNPATVTYYLMLDN
AMPK_b-2_Smoe    ---------------R-L------GFEKGQLIDSLR---N-R---VQNPATVTYYLMLDN
AMPK_c_Smoe      -----------------L------GFERQLLIMDLL---NNESS---E------------
GK014_Glam       Y----------------N------ALNRQSTIDDIKRKFKAG---QTDSDTVCYQLIHDH
GK013_Glam       ---------------TKI-----SDWSATKIIRSLN---N-N---RHNQMTATYFLLCER
GK015_Glam       ---------------HRM------NLDAVECIRGLF---L-G---KHNASTATYTLLAEK


SNF1A_Dmel       KR------------------------FAD-DAAN--Q-----INEIN-----------NF
AMPKa2_Mmus      RR------------------------IMN-QAS-------------------------EF
AMPKa1_Mmus      RR------------------------IMN-EAK-------------------------DF
SNF1_Scer        KS------------------------LIK-DMKANKS-----VSDEL-----------DT
AMPKa2_Hsap      RR------------------------IMN-QAS-------------------------EF
AMPKa1_Hsap      RR------------------------IMN-EAK-------------------------DF
T01C8.1_Cele     KR------------------------IAD-ETAK---------LSIE-----------EF
Snf1_Ddis        KR------------------------GS-YE-N---E-----I---N-----------SP
1110_Tthe        HI------------------------KNGGKSVA--D-----I-CSD-----------DF
11543_Tthe       FI------------------------REGGKSNA--D-----L-QLM-----------KK
20428_Tthe       YK------------------------KNNYYNKE--------N-NQ--------------
21336_Tthe       HI------------------------RNGGKSIA--D-----I-SSE-----------NF
26498_Tthe       HI------------------------RNGGVSIA--D-----L-SRP-----------PP
4451_Tthe        HV------------------------QQGGS-LE--D-----I-FPQ-----------NQ
7432_Tthe        FQ------------------------RNYKQLKI--SKQKKEN-NQ--------QEQANN
27742_Tthe       HM------------------------KEGGQSKA--D-----I-NSP-----------IF
AMPK_Spur        KR------------------------IMD-EASK---------TQMK-----------DF
aak-1_Cele       KR------------------------NAD-ESSQ---------KAME-----------DF
CC1G_10117_Ccin  NR------------------------LGK-DLAVFAE-----A--ER-----------DA
AqueK057_Aque    RL------------------------MQS-HTQP--------G-D-D-----------SH
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      RR------------------------RMS-HGY---L-----I---D-----------EF
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      RR------------------------RMS-HGY---L-----I---D-----------EF
AMPK_b-1_Smoe    RK------------------------RTGGNGN---E-----L---S-----------EV
AMPK_b-2_Smoe    RK------------------------RTGGNGN---E-----L---S-----------EV
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       IFDEIIARSFGIIGEPESNPAGANRSIFD-SSSL---------SALG-----------NV
GK013_Glam       DI------------------------QVNGYK-W------------------------NF
GK015_Glam       AE------------------------ATKKSN-P--K-----M-SMAAIIGINGYEKADF


SNF1A_Dmel       -------F----------------------------------------------------
AMPKa2_Mmus      -------Y----------------------------------------------------
AMPKa1_Mmus      -------Y----------------------------------------------------
SNF1_Scer        -------F----------------------------------------------------
AMPKa2_Hsap      -------Y----------------------------------------------------
AMPKa1_Hsap      -------Y----------------------------------------------------
T01C8.1_Cele     -------Y----------------------------------------------------
Snf1_Ddis        -------NL---------------------------------------------------
1110_Tthe        -------DSSLLLP---NKRPAKKQYGSDLISTHEEK---ENQN----DTRCK-------
11543_Tthe       -------ARS------DNLNVLKQQN-TTHLSSQQQE---QRQK----PNQIANQIVTPI
20428_Tthe       ------------------------------------------------------------
21336_Tthe       -------DNTLLQP---NKPPQQNKH-ETILEDERQR---QSRK----NQRTK-------
26498_Tthe       -------KKTLSLNQENNQKETNESS-SK-K--IQE------QNTILMENKDKNGLQ-QD
4451_Tthe        --------PRQQQP---I---------QSQVSSRNTTSTTPNSS----AQTAT-------
7432_Tthe        --------------------------DSQKVEQQKQQ---QQ------QQQLQQQ----Q
27742_Tthe       -------DITLIEP---KKNNDQKY-----------------------------------
AMPK_Spur        -------Y----------------------------------------------------
aak-1_Cele       -------WE---------------------------------------------------
CC1G_10117_Ccin  -------Q----------------------------------------------------
AqueK057_Aque    -------L----------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      -------QE---------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -------QE---------------------------------------------------
AMPK_b-1_Smoe    -------Q----------------------------------------------------
AMPK_b-2_Smoe    -------QD---------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ASGGSGDHE---------------------------------------------------
GK013_Glam       -------D--------------------------EQ------------------------
GK015_Glam       -------DN-----------------------LEVK------------------------


SNF1A_Dmel       ----VAG-SPPPPPP---------------------------------------------
AMPKa2_Mmus      ----LAS-SPPS-G----------------------------------------------
AMPKa1_Mmus      ----LAT-SPPD------------------------------------------------
SNF1_Scer        ----LSQ-SPPTFQQ---------------------------------------------
AMPKa2_Hsap      ----LAS-SPPS-G----------------------------------------------
AMPKa1_Hsap      ----LAT-SPPD------------------------------------------------
T01C8.1_Cele     ----QV--TPNKGPG---------------------------------------------
Snf1_Ddis        -------VSPITTPI---------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       LQTVSTA-APPSVAATQSN-----N---------TQGQDNVTKFTIQHNQLYQIFQNYDS
20428_Tthe       --NTFI-FRPVQE-----------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       KQSVNIN-YSERVSAMNKQAPNKSSTPIKKGVDNK--------PPLQNFEQYVALQQ-RI
4451_Tthe        ------------------------------------------------------------
7432_Tthe        QQQIEITSSPKQNII---------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ----LAS-SPPPRE----------------------------------------------
aak-1_Cele       -----IGKTMKMG-----------------------------------------------
CC1G_10117_Ccin  ----LAAQDPLTGLL---------------------------------------------
AqueK057_Aque    ----LAT-SPITS-----------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      -----EMASPQTGPV---------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -----EMASPQTGPV---------------------------------------------
AMPK_b-1_Smoe    ----VSRSRVKNGYH---------------------------------------------
AMPK_b-2_Smoe    ----VARAFPQSFAP---------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       -----EDAMDPSGPV---------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       -------------------PPV-PQSSMDHQAPLATVTVGGGTSASSGTATPV-PPVAGG
AMPKa2_Mmus      -------------------SFM-DDSAM-----------------------HI-PP----
AMPKa1_Mmus      -------------------SFL-DDHHL--------------------------------
SNF1_Scer        -----------------QS------KS--HQKS------------------QV-DH----
AMPKa2_Hsap      -------------------SFM-DDSAM-----------------------HI-PP----
AMPKa1_Hsap      -------------------SFL-DDHHL--------------------------------
T01C8.1_Cele     -------------------P----------------------------------------
Snf1_Ddis        -----------------MSSAQ-KSPIM-----------------------FTTTT----
1110_Tthe        ------------------NSVL-NSRKES-------------------------------
11543_Tthe       LKEKEDIKEFSP---AKNISYI-NPA----------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------ETRI--------------------------------------
26498_Tthe       NKEKQ--KDSTPESKGKNGSYL-NSPLIQ-------------------------------
4451_Tthe        ------------------GSFT-NQYNVN-------------------------------
7432_Tthe        ---------------------------FS-------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        -------------------SYL-EVQGVEN----V----------------HT-LC----
aak-1_Cele       -------------------------------------------------------S----
CC1G_10117_Ccin  -----------------SP------TALSPAAT------------------EI-DS----
AqueK057_Aque    -------------------SFIIVDTLLE-------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      -----------------SAKQL-QSPFM-----------------------HI-QS----
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -----------------SAKQL-QSPFM-----------------------HI-QS----
AMPK_b-1_Smoe    -----------------Q------------------------------------------
AMPK_b-2_Smoe    -----------------QSRQM-G---------------------------RV-HS----
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       -----------------ISQNP-FAPPE-----------------------AV-AP----
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       TPSSTIPI-----------RP--------------------H------------PER---
AMPKa2_Mmus      ------GL-----------KP--------------------H------------PER---
AMPKa1_Mmus      -------T-----------RP--------------------H------------PER---
SNF1_Scer        -----ETA-----------KQ--------------------H------------ARR---
AMPKa2_Hsap      ------GL-----------KP--------------------H------------PER---
AMPKa1_Hsap      -------T-----------RP--------------------H------------PER---
T01C8.1_Cele     -------V-----------HR--------------------H------------PER---
Snf1_Ddis        ------GF-----------NP--------------------S------------NSNSIS
1110_Tthe        -------------------R----------------------------------------
11543_Tthe       --------------------P--------------------Q--------------A---
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       -------------------SP--------------------EQNSKNADARILKEDK---
4451_Tthe        -------------------Q----------------------------------------
7432_Tthe        -------------------NN---------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------AG-----------KP--------------------ES-----------DDR---
aak-1_Cele       ------TS-----------LPVGATTKSE------------K------------SER---
CC1G_10117_Ccin  -----NPFEAELNAEYEEEEEYL------------------S------------EDE---
AqueK057_Aque    -------------------RD--------------------H------------SQK---
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------QR-----------GP--------------------S------------PS----
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------QR-----------GP--------------------S------------PS----
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------TT---------------------------------S------------PL----
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------AK-----------GPLLPSQEHEFSGLVFNTYVRTL------------PPT---
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        NNNNNNNNNNNNTTNNNNNTTNNNNSIINNNNINNNNINNNNNNNNNNINNNNIINNNNN
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        ------------------------------------------------------------
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ---------------------------------IAPMRDR---------Q------LA--
AMPKa2_Mmus      ---------------------------------MPPLIAD-------S-P------KA--
AMPKa1_Mmus      ---------------------------------VPFLVAE-------T-P------RA--
SNF1_Scer        ---------------------------------MASAITQ-QRTYHQS-PFMDQYKEE--
AMPKa2_Hsap      ---------------------------------MPPLIAD-------S-P------KA--
AMPKa1_Hsap      ---------------------------------VPFLVAE-------T-P------RA--
T01C8.1_Cele     ---------------------------------IAASVS----------S------KI--
Snf1_Ddis        NNNNNNNNNNNNNNNNNNNNNNSSISGGTEVFSISPNLNN-------S-Y------NS--
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ---------------------------------KPREYSH-------Q-P------REAE
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ---------------------------------QPFVVVK-------S-P------L---
4451_Tthe        ------------------------------------------------------------
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ---------------------------------VKPALAN-------T-S------MT--
aak-1_Cele       ---------------------------------NVAKVVGKF-----SAN------VG--
CC1G_10117_Ccin  ---------------------------------LDSFIAA-------P-P------AT--
AqueK057_Aque    ---------------------------------DS-LTNA-------S-P------V---
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ---------------------------------LNPEA--SL-----SP-------NA--
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------DHSYSYTNANNLNSKLCSSQ----------------------NSASKDVDNILN
11543_Tthe       QQQNKEKHPNKYHS------------------------------------ASPTREHHIE
20428_Tthe       ------------------------------------------------------------
21336_Tthe       --------SVS---------------------------------------ATKELDNQSQ
26498_Tthe       ------------------------------------------------------KNKQIS
4451_Tthe        ------SNNYPNSSTISQNQQ----VQNSQNSANYQNYNQQQNVSPVSVNPQQQYDPQTQ
7432_Tthe        ---------------------------------------------------SPDQEKLIN
27742_Tthe       --------SHNYLN--K----LIRDV----------------------KNTSEK------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        NNTAQLNQAN-QYKKEN------T---------NNT--------SM--------------
11543_Tthe       ------------E-----------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       Q---------------S------SN---QQTTITQN--------YEIQN----------T
26498_Tthe       ------------YDES-E-----SS---NKSP----------------------------
4451_Tthe        Q---------------S------NDQIEAQKRIQQQ--------YQMQQ----------Q
7432_Tthe        QNNQQNNQKQ-QNQ---NQNQGEQ----------NLNLGVA-HKPIISQQFHASLNQSNQ
27742_Tthe       -KKMIQDQSG-IFDEKI------TN---TEKKGSGQ--------PLLQG----------A
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       -RKYA-EALNFELEE-DGRLIK--------------------------------------
GK015_Glam       -KKIC-EEIGIEIDS-ENNILHAE---------NNTMVTIGKLKLEVSG----------D


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       SM----------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        QQ----------------------------------------------------------
7432_Tthe        DINIQQYSSSSTQNLSESKSQKQNQEKQKQRIKTEPQQNNSKNQFQKVVAKNNQIAFLDL
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------MSV---
AMPKa2_Mmus      ------------------------------------------------------RCP---
AMPKa1_Mmus      ------------------------------------------------------RHT---
SNF1_Scer        ------------------------------------------------------DST---
AMPKa2_Hsap      ------------------------------------------------------RCP---
AMPKa1_Hsap      ------------------------------------------------------RHT---
T01C8.1_Cele     ------------------------------------------------------TPT---
Snf1_Ddis        ------------------------------------------------------NSSGNS
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------DCT---
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        ------------------------------------------------------------
7432_Tthe        YQKQIELNTSNEEYYNGSGVQNMRNAYVSALGNYQNQLLQISTEQESYNLNQVAQIA---
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------MNT---
aak-1_Cele       ------------------------------------------------------RK----
CC1G_10117_Ccin  ------------------------------------------------------DPT---
AqueK057_Aque    ------------------------------------------------------SST---
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------RKV---
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       --------------------------------------------QT--SG----------
AMPKa2_Mmus      --------------------------------------------LD--AL----------
AMPKa1_Mmus      --------------------------------------------LD--EL----------
SNF1_Scer        --------------------------------------------VS--IL----------
AMPKa2_Hsap      --------------------------------------------LD--AL----------
AMPKa1_Hsap      --------------------------------------------LD--EL----------
T01C8.1_Cele     --------------------------------------------LD--------------
Snf1_Ddis        NGSNSNNNSNNNTNNDNNNNNNNNNNNNNNNNNNNNNNNNNNNCID--SV----------
1110_Tthe        ----------------------------------------------------T-------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       --------------------------------------------VE--TNNAY-------
21336_Tthe       ----------------------------------------------------N-------
26498_Tthe       ----------------------------------------------------N-------
4451_Tthe        ----------------------------------------------------QQQQQQQQ
7432_Tthe        --------------------------------------------NL--QAQSP-------
27742_Tthe       ----------------------------------------------------Y-------
AMPK_Spur        --------------------------------------------LE--NF----------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  --------------------------------------------FA--VL----------
AqueK057_Aque    --------------------------------------------GG--GM----------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       --------------------------------------------DGAEAV----------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        YNPNLDQENQEAIKLQIAQFEQQQQQLIEQQQKELLLKQMQMEEEQKQKQIFLQQQQAAE
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        --------------------------------------------------ID--------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       --------------------------------------------------ID--------
21336_Tthe       --------------------------------------------------MN--------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        EQRRKKQQQEEQEMIRLQLLKQQQYEEELARQLQKQREEQLRIQLLEEEQQR--------
7432_Tthe        --------------------------------------------------YNTNLALIKT
27742_Tthe       --------------------------------------------------IS--------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       -----------------------GG----------A------------------------
AMPKa2_Mmus      -----------------------NTT----------------------------------
AMPKa1_Mmus      -----------------------NPQ----------------------------------
SNF1_Scer        -----------------------PTSLP-QIHRANMLAQ-GS------------------
AMPKa2_Hsap      -----------------------NTT----------------------------------
AMPKa1_Hsap      -----------------------NPQ----------------------------------
T01C8.1_Cele     -----------------------NTE----------------------------------
Snf1_Ddis        -----------------------NNS---------LNNE-NDVNNSNINNNNNNNSDDGS
1110_Tthe        ----------------Q-------------------------------------------
11543_Tthe       ----------------------N-------------------------------------
20428_Tthe       -----------------Q----IFNQ----------------------------------
21336_Tthe       ----------------DL-KGTQ-------------------------------------
26498_Tthe       ---------------------IS-------------------------------------
4451_Tthe        ----------------AKAKLEE-------------------------------------
7432_Tthe        VQFQKSNAQNQNQIVANSEN--ITPK----------------------------------
27742_Tthe       ----------------NSYTNKV-------------------------------------
AMPK_Spur        -----------------------NNQ---------S------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  -----------------------NSSLPEQLPEQHHLTS-YV------------------
AqueK057_Aque    -----------------------TKH---------RSTS-LV------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       -----------------------SSN---------TDDGCYN------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ----------------------------------------FP-----------------E
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ----------------------------------------PA----------------AS
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        NNNSYEGGGDVLLLSDLNGNNQLGGNDNGNVVNLNNNFQLLN----------------SL
1110_Tthe        ----------------------------------------------------------KS
11543_Tthe       ----------------------------------------------------------QN
20428_Tthe       -----------------------------------------G----------------KL
21336_Tthe       ----------------------------------------------------------NS
26498_Tthe       ----------------------------------------------------------PN
4451_Tthe        ----------------------------------------------------------QM
7432_Tthe        -----------------------------------------NNNNNNNNNKQKNSENKQL
27742_Tthe       ----------------------------------------------------------YD
AMPK_Spur        ----------------------------------------SE-----------------S
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ----------------------------------------SA----------------KR
AqueK057_Aque    ----------------------------------------IE----------------DS
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ----------------------------------------DQTKVASGGLTLAQFRDGLN
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       KTAR------GGTP----------------------------------------------
AMPKa2_Mmus      --KP------KSLA----------------------------------------------
AMPKa1_Mmus      --KS------KHQG----------------------------------------------
SNF1_Scer        KISP------LVTK----------------------------------------------
AMPKa2_Hsap      --KP------KSLA----------------------------------------------
AMPKa1_Hsap      --KS------KHQG----------------------------------------------
T01C8.1_Cele     --AS------GANR----------------------------------------------
Snf1_Ddis        DLNS------DIQT----------------------------------------------
1110_Tthe        TANS------KYPSYKSSKRNSIQTNKLS-------------------------------
11543_Tthe       QQKQ--------------------------------------------------------
20428_Tthe       EEVT------EEEE----------------------------------------------
21336_Tthe       LILS------QKNNLQRPVTN----QGINNSQLPNILNSNIIPQNVQNRKIGSRNAQN--
26498_Tthe       TNKS------KY------------------------------------------------
4451_Tthe        RQQALIEEQQKKKLLEEQQQFLLRKQKQDEEYEQNL---------------------KQQ
7432_Tthe        EDLQ--------QN----------------------------------------------
27742_Tthe       NESQ------KTIKNRRGRQH---------------------------------------
AMPK_Spur        QRRV------SATP----------------------------------------------
aak-1_Cele       ILEG------LKKE----------------------------------------------
CC1G_10117_Ccin  SARS------GEKK----------------------------------------------
AqueK057_Aque    VPIR------LPRS----------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      --ND------ISRF----------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      --ND------ISRF----------------------------------------------
AMPK_b-1_Smoe    --AR------CWNI----------------------------------------------
AMPK_b-2_Smoe    --LE------VPRL----------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       GSLR------SEKV----------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ----------------KVGKH---------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       -----------------------------------QGKIYEYPK----------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        QYLAQKQAQMQQQQQQYKQQLIQQQQQQQVPVTSNHSQKYQNPSPQQQAVTTYNEAMQIN
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        --------------------------YN-----------------------SENQYP---
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ---PNSNNYFYDSQSP-SPIKPLYIAGN-----------------------QNGNDSNKS
26498_Tthe       ------------------------------------------------------------
4451_Tthe        TYSPSSQ-HNYGQNQPPSFAQPFAYQNSNNLKLPEDNQFRESLSNNNNRQSAAPSFSNQT
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------FYSNAS
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       --------------------------------------------------------KS--
GK015_Glam       ------------------------------------------------------LHSNTS


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ----------------------------------------------------NT---TKP
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       EGYQNA----------------------------------------VNTINNGIFNSAIP
26498_Tthe       ------------------------------------------------------------
4451_Tthe        D---SMIEINENNQAPCLNLEDFDQANSNTSLNANEQCEQVRKSIGENT--------PTP
7432_Tthe        ------------------------------------------------------------
27742_Tthe       D---LA----------------------------------------INDNNTSF---TNP
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       D---AS----------------------------------------TKD-----------


SNF1A_Dmel       ------------------------------IKRAKWHLGIRS------------------
AMPKa2_Mmus      ------------------------------VKKAKWHLGIRS------------------
AMPKa1_Mmus      ------------------------------VRKAKWHLGIRS------------------
SNF1_Scer        ------------------------------KSKTRWHFGIRS------------------
AMPKa2_Hsap      ------------------------------VKKAKWHLGIRS------------------
AMPKa1_Hsap      ------------------------------VRKAKWHLGIRS------------------
T01C8.1_Cele     ------------------------------NKRAKWHLGIRS------------------
Snf1_Ddis        ------------------------------QPHRKWYLGAIS------------------
1110_Tthe        VANNNYVFDGNQI--------------ANPNVHPYPQMNIHS------------------
11543_Tthe       ---------------------------------KTVELGIKD------------------
20428_Tthe       ------------------------------EILGQWTYGKIY------------------
21336_Tthe       ------------NSFKYPTHPSSMTASPRQAAQGRFESRMRQ------------------
26498_Tthe       ---------------------------------QDLQ----SSQKEKQSGEINFIKGYSL
4451_Tthe        ------------KK--------------LEFNNQPNRLSIED------------------
7432_Tthe        ------------------------------NNQNSYQANLQQ------------------
27742_Tthe       ------------NST------------ISHIQNQSYHLSPSS------------------
AMPK_Spur        ------------------------------VKRSKWHLGIRS------------------
aak-1_Cele       ------------------------------QKKLTWNLGIRA------------------
CC1G_10117_Ccin  ------------------------------QHRTKWHFGIRS------------------
AqueK057_Aque    ------------------------------FKKPKWHLGIRS------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------TAERRWALGLQS------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------TAERRWALGLQS------------------
AMPK_b-1_Smoe    ------------------------------GSERRWALGLQS------------------
AMPK_b-2_Smoe    ------------------------------QAERRWALGLQS------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------DKKSMFYFGVTG------------------
GK013_Glam       ----------------------------------------DS------------------
GK015_Glam       ------------------------------------AV-AQD------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        -------------Q----------------------------------------------
11543_Tthe       -------------N----------------------------------------------
20428_Tthe       -------------S----------------------------------------------
21336_Tthe       -------------A----------------------------------------------
26498_Tthe       TESTVRKQNFFQEE----------------------------------------------
4451_Tthe        -------------QQKRSKKNSVSNSQEFKYFQKEQREEIYVANTKKSIDLTQSQRNSIQ
7432_Tthe        -------------Q----------------------------------------------
27742_Tthe       -------------K----------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       -------------CNIA-------------------------------------------
GK013_Glam       -------------G----------------------------------------------
GK015_Glam       -------------P----------------------------------------------


SNF1A_Dmel       ---------QSKPND---------------------------------------------
AMPKa2_Mmus      ---------QSKACD---------------------------------------------
AMPKa1_Mmus      ---------QSRPND---------------------------------------------
SNF1_Scer        ---------RSYPLD---------------------------------------------
AMPKa2_Hsap      ---------QSKPYD---------------------------------------------
AMPKa1_Hsap      ---------QSRPND---------------------------------------------
T01C8.1_Cele     ---------QSRPED---------------------------------------------
Snf1_Ddis        ---------QLPPHE---------------------------------------------
1110_Tthe        ----------TNQQS---------------------------------------------
11543_Tthe       ----------MVPEF---------------------------------------------
20428_Tthe       ----------NSART---------------------------------------------
21336_Tthe       ----------ANPNE---------------------------------------------
26498_Tthe       ----------EQINN---------------------------------------------
4451_Tthe        YNNFMAGEENPRPYD---------------------------------------------
7432_Tthe        ----------ASGNLISNIPLHVYHTNIQSKKTSQVDISTQKYFKYSLKKRNLCINEYSV
27742_Tthe       ----------NQRNG--------------------Y------------------------
AMPK_Spur        ---------QSRPHD---------------------------------------------
aak-1_Cele       ---------CLDPVE---------------------------------------------
CC1G_10117_Ccin  ---------RSPPME---------------------------------------------
AqueK057_Aque    ---------QSHPQN---------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ---------RASPRD---------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ---------RASPRD---------------------------------------------
AMPK_b-1_Smoe    ---------RAHPRE---------------------------------------------
AMPK_b-2_Smoe    ---------RAHPRE---------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ---------VMPPPD---------------------------------------------
GK013_Glam       ----------AKVED---------------------------------------------
GK015_Glam       ----------ASDRG---------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        ------------------------------------------------------------
7432_Tthe        DNAKNYDQTPSPKDPPIFSVSQDTFYQKAQQIQQTKHQKDIQQPKVGNQLKKHSEHIKSN
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        ------------------------------------------------------------
7432_Tthe        VINNNSNHSLQKQIFYLNESDKKIETIKKIIDSVRSTKNSFNPPQQITPRMKIFSKIQNS
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        ------------------------------------------------------------
7432_Tthe        NNNTNQIHDIFSKRKSVPLYLSPQKEDVFSSSQNEAYRNIFQNNQMQSKQQQMIEESKLN
27742_Tthe       -------------------------------------H----------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ---------IMLEV--Y-RAMKAL--SY--------------------------------
AMPKa2_Mmus      ---------IMAEV--Y-RAMKQL--GF--------------------------------
AMPKa1_Mmus      ---------IMAEV--C-RAIKQL--DY--------------------------------
SNF1_Scer        ---------VMGEI--Y-IALKNL--GA--------------------------------
AMPKa2_Hsap      ---------IMAEV--Y-RAMKQL--DF--------------------------------
AMPKa1_Hsap      ---------IMAEV--C-RAIKQL--DY--------------------------------
T01C8.1_Cele     ---------IMFEV--F-RAMKQL--DM--------------------------------
Snf1_Ddis        ---------IMGEI--Y-RALKKV--GF--------------------------------
1110_Tthe        ---------IQQQI--I-YQQQQL--QQ--------------------------------
11543_Tthe       ---------VDITH--I-QKASQA--DQKLASLLDNTQKLGNQG----------------
20428_Tthe       ---------IMKAI--Y-EVASQL--DI--------------------------------
21336_Tthe       ---------IQEPS----R-------HS--------------------------------
26498_Tthe       ---------ISATK--DKQNIQNI--DVEN--------QINNQQAYTSTFGSGFKLSEKG
4451_Tthe        ---------HVLQP--E-PIPQSI--QN--------------------------------
7432_Tthe        QNNMSNQKQLSNKS--V-KTYKTLNPSM--------------------------------
27742_Tthe       ---------SVAPVNYS-QSQKAK--SY--------------------------------
AMPK_Spur        ---------IMGEV--F-RAMKAL--NF--------------------------------
aak-1_Cele       ---------TMKHV--F-LSLKSV--DM--------------------------------
CC1G_10117_Ccin  ---------VMLEI--Y-RTLKTL--GM--------------------------------
AqueK057_Aque    ---------IMQEI--M-KKLKAL--NF--------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ---------IMNEV--L-KVLQDM--EV--------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ---------IMNEV--L-KVLQDM--EV--------------------------------
AMPK_b-1_Smoe    ---------IMNEV--L-KVLQEL--DV--------------------------------
AMPK_b-2_Smoe    ---------IMNEV--L-KVLQEL--DV--------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ---------MMCLI--L-ETMREL--GF--------------------------------
GK013_Glam       ---------TNADV--A-EAIEDS--HS--------------------------------
GK015_Glam       ---------SQEKV--T-MKINEK--DV--------------------------------


SNF1A_Dmel       EWKI--------------------------------------------------------
AMPKa2_Mmus      EWKV--------------------------------------------------------
AMPKa1_Mmus      EWKV--------------------------------------------------------
SNF1_Scer        EWAK--------------------------------------------------------
AMPKa2_Hsap      EWKV--------------------------------------------------------
AMPKa1_Hsap      EWKV--------------------------------------------------------
T01C8.1_Cele     EWKV--------------------------------------------------------
Snf1_Ddis        EWKL--------------------------------------------------------
1110_Tthe        N-----------------------------------------------------------
11543_Tthe       --------------------------------------NTN---IYLNPLQKRIPIDK--
20428_Tthe       VITI--------------------------------------------------------
21336_Tthe       S-----------------------------------------------------------
26498_Tthe       S---------------PIRKVKLNNIQQQQFQQSLQKGDTNIQKCIIDKNEENIKLDKQK
4451_Tthe        N-----------------------------------------------------------
7432_Tthe        VWQA--------------------------------------------------------
27742_Tthe       S-----------------------------------------------------------
AMPK_Spur        EWKV--------------------------------------------------------
aak-1_Cele       EWKV--------------------------------------------------------
CC1G_10117_Ccin  EWKE--------------------------------------------------------
AqueK057_Aque    DWKV--------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      LWKK--------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      LWKK--------------------------------------------------------
AMPK_b-1_Smoe    SWKK--------------------------------------------------------
AMPK_b-2_Smoe    SWKK--------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       KWRI--------------------------------------------------------
GK013_Glam       D-----------------------------------------------------------
GK015_Glam       ELKRETAELAATVPVIPVGQAKI-------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------LKQTSYMLQSSYQKKQNNFVDANY------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       -------------------------------------V----------------------
26498_Tthe       SQESENLLSEKSLSKNNEKSDDEQLAEKSPIKETKMQIEGENKIRNQNVVATETKSASLD
4451_Tthe        ------------------------------------------------------------
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ---------------------------------PGLGL----------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       --------------------ISNT-----QGSVP------------SQSKKQSIAKVNYL
20428_Tthe       ------------------------------------------------------------
21336_Tthe       -------------------------------GNN--------------------------
26498_Tthe       KKQINKTNNQNQQKVNGVNNLYNIQISKLHYNKAGQKARNGQESTSEISANKSDNQVTLQ
4451_Tthe        ------------------------------------------------------------
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       -------------------------------GLN------------LPAG----------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        --------NYFQAN-------------------------SALTSGTQSPYKHSSQQYAPY
11543_Tthe       NNSSMFEDPK--------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       --------TIVNQI-------------------------AGASTGSKQ-RQSKK------
26498_Tthe       NNSDIYQRTDA---------------------------------------NI--------
4451_Tthe        --------WNQHNQDNQNGTMSSNSSNYYKELQVVNQLLRD------------------S
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       --------PN--------------------------------------------------
GK015_Glam       --------PV-----------------------------AGGGAVTT--RN---------


SNF1A_Dmel       -I-NP---------------------------YH--VRV--R------------------
AMPKa2_Mmus      -V-NA---------------------------YH--LRV--R------------------
AMPKa1_Mmus      -V-NP---------------------------YY--LRV--R------------------
SNF1_Scer        -P-SEED------------------------LWT--IKL--R------------------
AMPKa2_Hsap      -V-NA---------------------------YH--LRV--R------------------
AMPKa1_Hsap      -V-NP---------------------------YY--LRV--R------------------
T01C8.1_Cele     -L-NP---------------------------YH--VIV--R------------------
Snf1_Ddis        -T-GP---------------------------YQ--LRC--R------------------
1110_Tthe        AQNNH---------------------------YNYSNTG--A------------------
11543_Tthe       -DSQK---------------------------YK--VNS--S------------------
20428_Tthe       -KNSE---------------------------YR--IKC--H------------------
21336_Tthe       --------------------------------------Q--E------------------
26498_Tthe       -NVQN---------------------------YK--ISSASR------------------
4451_Tthe        QQGNT---------------------------H--HIRE--QSYSQERETKQHAQTNQAH
7432_Tthe        --NEN---------------------------LQ--VKS--T------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        -V-NP---------------------------FY--VRV--R------------------
aak-1_Cele       -L-SM---------------------------YH--IIV--R------------------
CC1G_10117_Ccin  -K-KNLGG-----------------------LGG--LKA--R------------------
AqueK057_Aque    -V-NT---------------------------YH--IRC--R------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      -N-GN---------------------------YN--VKC--R------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -N-GN---------------------------YN--VKC--R------------------
AMPK_b-1_Smoe    -L-GH---------------------------YN--VKC--R------------------
AMPK_b-2_Smoe    -L-GH---------------------------YN--VKC--R------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       -G-GLNASKYYDSNIGRDTVVLKTDTSKKRNNFC--VAF--K------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       -------------------------------------------------------RQ---
AMPKa2_Mmus      -------------------------------------------------------RK---
AMPKa1_Mmus      -------------------------------------------------------RK---
SNF1_Scer        -------------------------------------------------------WK---
AMPKa2_Hsap      -------------------------------------------------------RK---
AMPKa1_Hsap      -------------------------------------------------------RK---
T01C8.1_Cele     -------------------------------------------------------RK---
Snf1_Ddis        -------------------------------------------------------MV---
1110_Tthe        -------------------------------------------------------RN---
11543_Tthe       -------------------------------------------------------FQ---
20428_Tthe       -------------------------------------------------------RK---
21336_Tthe       -------------------------------------------------------AV---
26498_Tthe       -------------------------------------------------------RG---
4451_Tthe        PHNSQQTQAQMLINSTIPKNTVSITSNHSISNNSQANQNNPQVQNGAAAAQQQFTSA---
7432_Tthe        -----------------------------------NS------------------ER---
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        -------------------------------------------------------RT---
aak-1_Cele       -------------------------------------------------------SK---
CC1G_10117_Ccin  -------------------------------------------------------RQHHH
AqueK057_Aque    -------------------------------------------------------YK---
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      -------------------------------------------------------WN---
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -------------------------------------------------------WN---
AMPK_b-1_Smoe    -------------------------------------------------------WT---
AMPK_b-2_Smoe    -------------------------------------------------------WT---
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       -------------------------------------------------------LV---
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       --NV-K------------------------------------------------------
AMPKa2_Mmus      --NP-V------------------------------------------------------
AMPKa1_Mmus      --NP-V------------------------------------------------------
SNF1_Scer        --YDIGNKT---------------------------------------------------
AMPKa2_Hsap      --NP-V------------------------------------------------------
AMPKa1_Hsap      --NP-V------------------------------------------------------
T01C8.1_Cele     --PDAP------------------------------------------------------
Snf1_Ddis        --N---------------------------------------------------------
1110_Tthe        --TPSQN-N------------------------------------------TIQISY---
11543_Tthe       --YANASKY--S----------------------------------------V-------
20428_Tthe       --NPKKIQ---S----------------------------------------A---Y---
21336_Tthe       --QPLTS------------------------------------------------AA---
26498_Tthe       --NSSKE-E--S----------------------------------------V-------
4451_Tthe        --SPVSG-T--HKQNMNSNVAQSFSNNSNVRGSQTIAINNNSNNNGDSSKFISPRQS---
7432_Tthe        --NPIVNL---K----------------------------------------Q-------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        --NP-L------------------------------------------------------
aak-1_Cele       --PTPI------------------------------------------------------
CC1G_10117_Ccin  HQYHHHERGRASIE------------------------------------------RARE
AqueK057_Aque    --KSAD------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      --SPAPCSR--E--------------------------------------------AV--
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      --SPAPCSR--E--------------------------------------------AV--
AMPK_b-1_Smoe    --FAPPSKA--PCS------------------------------------------LP--
AMPK_b-2_Smoe    --FAPPSKA--PCS------------------------------------------LP--
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       --N-PA------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        -----------------------------NT--NE-------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------NNHLETIKSESSSNLSTNYTNNGNLNNSHH
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        ------------------------------------------------------------
7432_Tthe        ------------------------------KNSQQ-------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  YDG----------DGGVDLKAAAGIYCVETR--CR-------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      --GSPMVPGSPIHDNG---L-EKLVEQQQQQ--HK-------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      --GSPMVPGSPIHDNG---L-EKLVEQQQQQ--HK-------------------------
AMPK_b-1_Smoe    --GSPMI-SEPLHERI---AVAAATAAADIV--EQ-------------------------
AMPK_b-2_Smoe    --GSPMI-SEPLHERI---AVAAATAAADIV--EQ-------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       -----------------------T--GKFSKMSLQLY----QVDA----KSY--------
AMPKa2_Mmus      -----------------------T--GNYVKMSLQLY----LVDS----RSY--------
AMPKa1_Mmus      -----------------------T--STFSKMSLQLY----QVDS----RTY--------
SNF1_Scer        ----------------------KI--PDLMKMVIQLF----QIET----NNY--------
AMPKa2_Hsap      -----------------------T--GNYVKMSLQLY----LVDN----RSY--------
AMPKa1_Hsap      -----------------------T--STYSKMSLQLY----QVDS----RTY--------
T01C8.1_Cele     -----------------------A--ADPPKMSLQLY----QVDQ----RSY--------
Snf1_Ddis        --------------------------GKPIKLVLQLF----RVAE----NRY--------
1110_Tthe        -----------------------------LNETL-----------------K--------
11543_Tthe       ------------------------------GDEYEFY----QIQK----QNV--------
20428_Tthe       HHHSYNNHYHHVNPQNQNFTGFQS--GSNVSMTNNFQ----HTQT----NSY--------
21336_Tthe       -----------------------------QNNSL--------------------------
26498_Tthe       ------------------------------TTQLQLQ----IIQQ----SENPQQINQIS
4451_Tthe        -----------------------------MDGAL-----------------K--------
7432_Tthe        ----------------------NT--SQSQSQSLLNQ----QKDN----LLY--------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        -----------------------T--GAQIKLGLQLY----QVDS----KSY--------
aak-1_Cele       -----------------------N--PDPVKVSLQLF----ALDKKENNKGY--------
CC1G_10117_Ccin  ----------------------VQ--DVVVLMNLQLY----MVDS----INY--------
AqueK057_Aque    -----------------------E--SSVVKLDLQLY----QLDQ----RNF--------
AMPK_f_Smoe      -------------------------------------------------VSF--------
AMPK_e_Smoe      ----------------------IG--SSLVKFELQ-------VRE----EKY--------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ----------------------IG--SSLVKFELQLY----KVRE----EKY--------
AMPK_b-1_Smoe    ----------------------GR--RNLVKFEVQLY----KMHE----EKY--------
AMPK_b-2_Smoe    ----------------------GR--RNLVKFELQLY----KMHE----EKY--------
AMPK_c_Smoe      -------------------------------------------------VSF--------
GK014_Glam       -----------------------SAIQNDLIIGLTLYIAIDQSNH----ANY--------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       -----------------LLDFKSLT-NDEV------------------------------
AMPKa2_Mmus      -----------------LLDFKSID-DEVV------------------------------
AMPKa1_Mmus      -----------------LLDFRSID-DEIT------------------------------
SNF1_Scer        -----------------LVDFKFDG-WESS------------------------------
AMPKa2_Hsap      -----------------LLDFKSID-DEVV------------------------------
AMPKa1_Hsap      -----------------LLDFRSID-DEIT------------------------------
T01C8.1_Cele     -----------------LLDFKSLA-DEES------------------------------
Snf1_Ddis        -----------------LLDIKKIE-GE--------------------------------
1110_Tthe        ----------------------SVD--NSILNKI--------------------------
11543_Tthe       -----------------YLNFKLKR-EDKLIMVNSVQTNSNY-NKSGLYQNSKKT--VQD
20428_Tthe       -----------------LMPPQGNQFNNQMS-----------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       NTNQSKIIVKIHQKTKSETGF-----SRKLMNINGINQKENVNNESEEISNM-KSPQLKS
4451_Tthe        -----------------LLSNKQRD--ENVRQSANQSLTATNTPNSMNKKLKNNLNTLSV
7432_Tthe        -----------------YPDFAQNI-NKKSNK----------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        -----------------LLDFKSLT-NPRD------------------------------
aak-1_Cele       -----------------LLDFKGLT-EDEE------------------------------
CC1G_10117_Ccin  -----------------LVDFHHKK-TYKA------------------------------
AqueK057_Aque    -----------------LLDFKGVD-PSEE------------------------------
AMPK_f_Smoe      -----------------LAVFT--------------------------------------
AMPK_e_Smoe      -----------------LLDLQKLE-GP--------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -----------------LLDLQKLE-GP--------------------------------
AMPK_b-1_Smoe    -----------------LLDLQKLE-GP--------------------------------
AMPK_b-2_Smoe    -----------------LLDLQKLE-GP--------------------------------
AMPK_c_Smoe      -----------------LGAFT--------------------------------------
GK014_Glam       -----------------VVDLRMIT-GE--------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ---PQ-------------------------------------------------------
11543_Tthe       SALNTTQDSPKNKQSQNAN-------------------------------NLSMLLQRNY
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       SVAASSAHSQVNSQIKNTNEKIANLIRSANQKGGINAFQKDVSAQSQYKQYLP-VFFNNQ
4451_Tthe        TTSSS-------------------------------------------------------
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ----H-------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------YADSSF---------------------------------------------NNS
11543_Tthe       QFPI----NVGNKNVVNSNNNS-------------QNNFSKTRYLSVQRQQQISKPQNAT
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       QYSSSLNAPNTSNSIINNTINSSNINNNTIETEKQQQNQSSNNYYSKQ--------TLKT
4451_Tthe        ------KQPS-A---------------------------------------------KQS
7432_Tthe        --------------LQLIF-----------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------KTEK-L---------------------------------------------VDT


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        PRA-------------------------------------------NGKDPMEKLRNKIK
11543_Tthe       PTLEEKKNFRI---------------------SSYSIHMRGNSTQYN-------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ---------------------------------------------------------QTQ
26498_Tthe       PCITEPTYHETNSIRQKLKIISQRNSTQGTSAQAFKVRIRKS------------------
4451_Tthe        PSP---------------------------------------------------------
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       PTV-------------------------------------------K-------------


SNF1A_Dmel       -----------------------------------------E------------------
AMPKa2_Mmus      -----------------------------------------E------------------
AMPKa1_Mmus      -----------------------------------------E------------------
SNF1_Scer        -----------------------------------------Y------------------
AMPKa2_Hsap      -----------------------------------------E------------------
AMPKa1_Hsap      -----------------------------------------E------------------
T01C8.1_Cele     -----------------------------------------G------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ETNQKRSIKNGSNNGINSSGNQNDCSFINNS--------------------------NES
11543_Tthe       ---TRNSNDNVLNLSL---------------------------NQAATQNQS-KRASINS
20428_Tthe       -----------------------------------------NV-----------------
21336_Tthe       QTP---------------------------------------------------------
26498_Tthe       ----ATPELNNINSSINNN-----------S------------NQSNIQNTLFVNGSHNL
4451_Tthe        -----------------------------------------------------------K
7432_Tthe        ----------------------------NNSSNKSESNEKKQIN-----NIYFHH-----
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        -----------------------------------------S------------------
aak-1_Cele       -----------------------------------------A------------------
CC1G_10117_Ccin  -----------------------------------------S------------------
AqueK057_Aque    -----------------------------------------K------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        SRQQFNIPGTLGQRMRFANIKKNPNNMNANFT--NNQNMQSGH-------PQ--------
11543_Tthe       IKQQQPIPL-----------QEKLININLNFQGTNNTNT-------------KRLRKKII
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       VSQQQ-----------------KRSNSNNNI--TNNQNSATGNSSNLQTSPEKKFKTKQI
4451_Tthe        ------------------------------------------------------------
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ----------------------STLPSRGY---SQGRESKSHAS---QRQKQQQTGNKVR
11543_Tthe       S-----------------MHDTSYNP----------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       --------------------------TSQFSQNHWANRTRIHMRHISQAGK------RP-
26498_Tthe       SRSSRRFVSAERENNQMIQQSLVDDP----------------------------------
4451_Tthe        --------------------------------------SKSKLQ---QQQQQMQQQNSMH
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       --------------------------------------TS--------------------


SNF1A_Dmel       ---------------------------------QG-------------------------
AMPKa2_Mmus      ---------------------------------QR-------------------------
AMPKa1_Mmus      ---------------------------------AK-------------------------
SNF1_Scer        ---------------------------------GD-------------------------
AMPKa2_Hsap      ---------------------------------QR-------------------------
AMPKa1_Hsap      ---------------------------------AK-------------------------
T01C8.1_Cele     ---------------------------------SA-------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        GVTQERKG-V-S-----------------PIERERGKSTEPF------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       -------GSIQQ-----------------AYEKERGKSTEPQID----------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        --------SSVNNHSNGYHSTLPSHNIKLTNKSQSSGTSNNNNQNSLQNSQLGQSKLVNN
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ---------------------------------GM-------------------------
aak-1_Cele       ---------------------------------V--------------------------
CC1G_10117_Ccin  ---------------------------------TE-------------------------
AqueK057_Aque    ---------------------------------TE-------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       -------------------------------------SEAPEMT----------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        --------------------DDCNTSGYRILGIDNCNTSLNTS-----------------
11543_Tthe       ------------------------------------------TKQNSFNAGKMNKENSVA
20428_Tthe       -------------------------------SN---------------------------
21336_Tthe       --------------------DSANTSGYKILNASILDQSLNGSLNNTFVLNQT-------
26498_Tthe       ------------------------------------------TKNKFFRQ----------
4451_Tthe        TQTQQQNKPVSQSSSINSTQNAISVSNTQ-------------------------------
7432_Tthe        -------------------------------QSNNCSSHIQAS-----------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       --------------------VEYDDGGLRICKDDIT------------------------


SNF1A_Dmel       ------------------------------------DDV---------------------
AMPKa2_Mmus      ------------------------------------SGSSTPQRSCSAA-----------
AMPKa1_Mmus      ------------------------------------SGTATPQRSGSIS-----------
SNF1_Scer        ------------------------------------D-----------------------
AMPKa2_Hsap      ------------------------------------SGSSTPQRSCSAA-----------
AMPKa1_Hsap      ------------------------------------SGTATPQRSGSVS-----------
T01C8.1_Cele     ------------------------------------SASS--SRHASMS-----------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        --------------------GFHNNITINNP----T------------------------
11543_Tthe       SNSGSKQEIRIFNNMEFLSYGSVNN-NLNNH----S------------------------
20428_Tthe       ---------------------DFGQN-MESQSQSYAIGSNFNNMNYS--QSGYQF----D
21336_Tthe       --------------------AFINGHNINNG----G------------------------
26498_Tthe       ----------------------------GSSSIQKN------------------------
4451_Tthe        -----------------------QSIS---------------------------------
7432_Tthe        --------------------NLYQS--IQTKQIQL-NSS--STKACSSSHQLFQSEKKQN
27742_Tthe       ---------------------FHSNN-TNNH----I------------------------
AMPK_Spur        ------------------------------------T-----------------------
aak-1_Cele       ------------------------------------PPSRCRSRAASVS-----------
CC1G_10117_Ccin  ------------------------------------PGAGKFD----MA-----------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ---------------------------KEN------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ----------------------------------------GLHRAR---SSFD-------
AMPKa1_Mmus      ----------------------------------------NYRSCQ---RSDS-------
SNF1_Scer        ---------------------------------------------------TT-------
AMPKa2_Hsap      ----------------------------------------GLHRPR---SSFD-------
AMPKa1_Hsap      ----------------------------------------NYRSCQ---RSDS-------
T01C8.1_Cele     ----------------------------------------MPQKPAGIRGTRT-------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        --L---------G--------------------L--------------------------
11543_Tthe       --LELEI---------------------------------------------------EN
20428_Tthe       SGM---------N--------------------LNNGNTQNPNNSQ---NNALD------
21336_Tthe       --V---------GNKVQKANFNILQGITGFRTTA--------------------------
26498_Tthe       --IQNYLNIIEKNSASNMNNIHNTDKQNINVVIK-------------------KPENIDN
4451_Tthe        --------------------------MSNNNTSS-------------------QQGYSQN
7432_Tthe        QNI---------N--------------------KKKNQISNISKTQ---SSSS-------
27742_Tthe       --I---------G--------------------N--------------------------
AMPK_Spur        ----------------------------------------NFGS-------DD-------
aak-1_Cele       ----------------------------------------VTLAKS---KSDL-------
CC1G_10117_Ccin  ----------------------------------------HFEIPSD---SCS-------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        N-----------------------------------------------------------
11543_Tthe       NQKNLQQNYQTC--------------------------NGTRGNKIDVNNSLVLPKG---
20428_Tthe       ------------------------------------------------------------
21336_Tthe       N-S-GAQ-----------------------------------------------------
26498_Tthe       NGQSFQSEMKKQ--------------------------DQTNNQTPSINKEVK-------
4451_Tthe        NINSNNQQKNSKNNDISENLATEPNYTSKHVQQSSQSSNGQYQNSSNINNGQIKNHSLSI
7432_Tthe        ------------------------------------------------------------
27742_Tthe       NNNNNNQNYNNS------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      ------------------------------------------------------------
AMPKa1_Mmus      ------------------------------------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ------------------------------------------------------------
AMPKa1_Hsap      ------------------------------------------------------------
T01C8.1_Cele     ------------------------------------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------IPRVHTDENDKNN-----------------------------------------
20428_Tthe       ------------------------------------------------------------
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------EPKIRVISESPMCK----------------------------------------
4451_Tthe        SKQNAVSPRI---------ATENSDPYYRQHIYQNNSNSSSSKSYMNSSKISPSTTTNAS
7432_Tthe        ------------------------------------------------------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ------------------------------------------------------------
aak-1_Cele       ------------------------------------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       ------------------------------------------------------------
AMPKa2_Mmus      -------------------------------------------------SSTAEN-----
AMPKa1_Mmus      -------------------------------------------------DAEAQG-----
SNF1_Scer        -------------------------------------------------V----------
AMPKa2_Hsap      -------------------------------------------------STTAES-----
AMPKa1_Hsap      -------------------------------------------------DAEAQG-----
T01C8.1_Cele     -------------------------------------------------SSMPQA-----
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ------------------------------------------------------------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       --------------------------------------------------TNNIP-----
21336_Tthe       ------------------------------------------------------------
26498_Tthe       ------------------------------------------------------------
4451_Tthe        YQNKHLTVQSGIKVHRGPFNLRAITNKDPKYIVSELIKTLESFKMYYKPTSKFDI-----
7432_Tthe        ----------------------------------------------------QLI-----
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        -------------------------------------------------RMEVEE-----
aak-1_Cele       -------------------------------------------------NGNSSKVPMSP
CC1G_10117_Ccin  -------------------------------------------------ESERSV-----
AqueK057_Aque    ------------------------------------------------------------
AMPK_f_Smoe      --------------------------------------------------RYVSI-----
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      --------------------------------------------------RYISI-----
GK014_Glam       ------------------------------------------------------------
GK013_Glam       --------------------------------LENI------------------L-----
GK015_Glam       ---------------------GVVTTVQYEDLVVRLKQVFKELRIKADSEREGSF-----


SNF1A_Dmel       ------------------------------IME---------SL--T---PPP-LS-VS-
AMPKa2_Mmus      ----------------------HS--LSGSLTG---------SL--T---G---ST-LS-
AMPKa1_Mmus      ----------------------KP--SDVSLTS---------SV--T---SLD-SS-PV-
SNF1_Scer        --------------------------------S---------NI--------------S-
AMPKa2_Hsap      ----------------------HS--LSGSLTG---------SL--T---G---ST-LS-
AMPKa1_Hsap      ----------------------KS--SEVSLTS---------SV--T---SLD-SS-PV-
T01C8.1_Cele     ----------------------MS--MEASIEK--------MEV--H---DFS-DM-SC-
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        --------------------------------S-----------SLKN-NTTNS------
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ----------------------KF--SKQDLVF---------TI--QI-YQMPSTS----
21336_Tthe       ---------------------------NNYLNA-----------SLNT-S-IDN------
26498_Tthe       -----------------------------------------------KDQHSNE------
4451_Tthe        ----------------------RV--EKDLVKF---------DISVNI-LHNVE------
7432_Tthe        ----------------------EQQQFQNQEQL---------AQ--NL-IQMTSSQYANP
27742_Tthe       ---------------------------NNIYNN-----------ILQN-DYSSQ------
AMPK_Spur        ----------------------PM--SPRSPT-----------T--P---TLP----QS-
aak-1_Cele       LSPMSPISPSVNIPKVRVDDADAS--LKSSLNSSIYMADIENSM--E---SLDEVS-TQ-
CC1G_10117_Ccin  ----------------------KE--KEGC--F---------GI--------------G-
AqueK057_Aque    ----------------------------VSI--------------------------LG-
AMPK_f_Smoe      ----------------------V-----------------------------------C-
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ----------------------L-----------------------------------C-
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ----------------------KI--QRED---------------------TQS------
GK015_Glam       ----------------------KC--ERMNVQF---------SI--DI-YRIGSA--IS-


SNF1A_Dmel       --------------------------------------------G---------------
AMPKa2_Mmus      --------------------------------------------S---------------
AMPKa1_Mmus      --------------------------------------------D---------------
SNF1_Scer        --------------------------------------------E---------------
AMPKa2_Hsap      --------------------------------------------S---------------
AMPKa1_Hsap      --------------------------------------------D---------------
T01C8.1_Cele     --------------------------------------------D---------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ---------------------------------------NNYSFDLGNYAQLQLSQQQQI
11543_Tthe       ------------------------------------------------------------
20428_Tthe       ------------------------------------IQSDQHIVDV--------------
21336_Tthe       ---------------------------------------RNNQIGF--------IQQNGN
26498_Tthe       ---------------------------------------SKYYLGLKQ--QM-I------
4451_Tthe        ---------------------------------------NLFIIKF--------------
7432_Tthe        EIASKSYSFQKLNILNHTNSTCEDGSVMVIQPNEQLMNSQKYNEDI--------------
27742_Tthe       ---------------------------------------NPYLQQN--------------
AMPK_Spur        --------------------------------------------P---------------
aak-1_Cele       --------------------------------------------S---------------
CC1G_10117_Ccin  --------------------------------------------G---------------
AqueK057_Aque    --------------------------------------------G---------------
AMPK_f_Smoe      --------------------------------------------S---------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      --------------------------------------------S---------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ---------------------------------------DRSLNDL--------------
GK015_Glam       ---------------------------------------PQLGILM--------------


SNF1A_Dmel       -----------------------------------VM-----------------------
AMPKa2_Mmus      -----------------------------------AS-----------------------
AMPKa1_Mmus      -----------------------------------VA-----------------------
SNF1_Scer        -----------------------------------D------------------------
AMPKa2_Hsap      -----------------------------------VS-----------------------
AMPKa1_Hsap      -----------------------------------LT-----------------------
T01C8.1_Cele     -----------------------------------VTPPPS-------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        QITQQL-----------------NSSFQH-------------N-GY--------------
11543_Tthe       ----------------------------Q-------------NKNGNNQN----------
20428_Tthe       ---I---------------------------------L----------------------
21336_Tthe       FKQNNL-----------------NSTAYH-------------NFNLGNKN----------
26498_Tthe       -----Q-----------------KEPLIC-------------NFSINNDS----------
4451_Tthe        ---T--------------------------------------------------------
7432_Tthe        ---RLNTSEEKLVSVSVHKHLNLQESVKRPQTNSQVSINPNKN-G-IDQLNIIQNFEKSS
27742_Tthe       ---QQL-----------------QAALLH-------------Q-----------------
AMPK_Spur        -----------------------------------GS-----------------------
aak-1_Cele       -----------------------------------SE-----------------------
CC1G_10117_Ccin  -----------------------------------R------------------------
AqueK057_Aque    -----------------------------------GS-----------------------
AMPK_f_Smoe      -----------------------------------L------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      -----------------------------------L------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ---A--------------------------------------------------------
GK015_Glam       ---R--------------------------------------------------------


SNF1A_Dmel       ---------------------------PL-------------------------------
AMPKa2_Mmus      ---------------------------PR-------------------------------
AMPKa1_Mmus      ---------------------------PR-------------------------------
SNF1_Scer        ------------------------------------------------------------
AMPKa2_Hsap      ---------------------------PR-------------------------------
AMPKa1_Hsap      ---------------------------PR-------------------------------
T01C8.1_Cele     ---------------------------PG-------------------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ----------SNS------------------NINCN----IVP-----------------
11543_Tthe       --KINAI-QINNSN----------------------NSNAISQRSKK--TDQSKSENIKL
20428_Tthe       ------------------------------------------------------------
21336_Tthe       --KLNNILGVQNSNRVGTAVNYDYNATPSIANTNNN----IYKKNY--------------
26498_Tthe       --NINHH-LTNNDG------------------INSTIDDIVQQKSNQKLTSWPHSQNYYL
4451_Tthe        ------------------------------------------------------------
7432_Tthe        PKNNNYS-QIENSQ-----------------KTNNNSQKILSQKHL--------------
27742_Tthe       ------------------------------------------------------------
AMPK_Spur        ---------------------------PR-------------------------------
aak-1_Cele       ---------------------------PE-------------------------------
CC1G_10117_Ccin  ------------------------------------------------------------
AqueK057_Aque    ---------------------------PQ-------------------------------
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       ------------------------------------------------------------
GK015_Glam       ------------------------------------------------------------


SNF1A_Dmel       --------------------------------Q-----PTG-------------------
AMPKa2_Mmus      --------------------------------------L-G-------------------
AMPKa1_Mmus      --------------------------------------P-G-------------------
SNF1_Scer        --------------------------------E-----MST-------------------
AMPKa2_Hsap      --------------------------------------L-G-------------------
AMPKa1_Hsap      --------------------------------------P-G-------------------
T01C8.1_Cele     --------------------------------G-----AKL-------------------
Snf1_Ddis        ------------------------------------------------------------
1110_Tthe        ---------SSIQSSNTT--------KSSSQSH-----RRG---KSSPLQNILNKLEKNK
11543_Tthe       NKILPFSIQ----TNQIANNSMVAGNINNLQIQQNLNQNSQGGGSSQ-------------
20428_Tthe       ---------------------------------------NK-------------------
21336_Tthe       ----PQ---TTFNSNNVS--------LNSSQIQ-----------S---------------
26498_Tthe       NAPVTHSNNKSY-LNNISNSSRISSQLNEQQLQS-----LQPPT--M-------------
4451_Tthe        --------------------------------------RLI-------------------
7432_Tthe        ---------------------------KVLNNQ-----LQN-------------------
27742_Tthe       -------------NSN-----------NSSSQQ-----RKG---SSY-------------
AMPK_Spur        --------------------------------------CMQ-------------------
aak-1_Cele       --------------------------------A-----PIR-------------------
CC1G_10117_Ccin  --------------------------------E-----DEV-------------------
AqueK057_Aque    --------------------------------L-----PQR-------------------
AMPK_f_Smoe      --------------------------------T-----MQA-------------------
AMPK_e_Smoe      ------------------------------------------------------------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ------------------------------------------------------------
AMPK_b-1_Smoe    ------------------------------------------------------------
AMPK_b-2_Smoe    ------------------------------------------------------------
AMPK_c_Smoe      --------------------------------T-----MQA-------------------
GK014_Glam       ------------------------------------------------------------
GK013_Glam       --------------------------------------SEQ-------------------
GK015_Glam       --------------------------------------RIS-------------------


SNF1A_Dmel       -------------HHTM---------------EFFE-MC-A----ALII-----------
AMPKa2_Mmus      -------------SHTM---------------DFFE-MC-A----SLIT-----------
AMPKa1_Mmus      -------------SHTI---------------EFFE-MC-A----NLIK-----------
SNF1_Scer        -------------FSAY---------------PFLH-LT-T----KLIM-----------
AMPKa2_Hsap      -------------SHTM---------------DFFE-MC-A----SLIT-----------
AMPKa1_Hsap      -------------SHTI---------------EFFE-MC-A----NLIK-----------
T01C8.1_Cele     -------------SQTM---------------QFFE-IC-A----ALIG-----------
Snf1_Ddis        ---------------IF---------------IFFD-IC-S----LMLE-----------
1110_Tthe        NIQQGNNNNNYNLNNSFNLNNTYNGPAAYISSNYTTKNQ-N----QQ-------------
11543_Tthe       --------SS-GRVPSY---------------KFRK-V----------------------
20428_Tthe       -------------GHPI---------------MFLE-FF-N----QFLT-----------
21336_Tthe       --------NNDSLNTSI---------------NFNNTMYGS----VN-------------
26498_Tthe       --------EN-SRSEHL---------------KFKA-VT-N----SLIS-----------
4451_Tthe        -------------GDTH---------------KYNE-IC-N----NILN-----------
7432_Tthe        -------------GMSQ---------------INTQ-LF-K----KYLTLNTNESKMFPQ
27742_Tthe       --------NQYRINLRINNQK----P-------Y--QKK-T----TI-------------
AMPK_Spur        -------------HCTM---------------EFFE-MC-A----SLIA-----------
aak-1_Cele       -------------SQTM---------------EFFA-TC-H----IIMQ-----------
CC1G_10117_Ccin  -------------VSPF---------------VFMD-VA-C----RLIL-----------
AqueK057_Aque    -------------HYTM---------------EFFE-AC-S----RLIC-----------
AMPK_f_Smoe      -------------AVTY---------------YIIL-NC-D----RQIS-----------
AMPK_e_Smoe      ---------------FF---------------IFLD-FC-G----SFLA-----------
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      ---------------FF---------------IFLD-FC-G----SFLA-----------
AMPK_b-1_Smoe    ---------------FF---------------TFLD-FC-T----MFLA-----------
AMPK_b-2_Smoe    ---------------FF---------------TFLD-FC-S----MFLA-----------
AMPK_c_Smoe      -------------AVTY---------------YIIL-NC-D----RQIS-----------
GK014_Glam       ---------------LN---------------LFLH-YA-QRIGQAITE-----------
GK013_Glam       -------------GY-------------------------------GP------------
GK015_Glam       -------------GDGA---------------IYKE-IG-Q----IVF------------


SNF1A_Dmel       -------------------------------------------------------Q----
AMPKa2_Mmus      -------------------------------------------------------A----
AMPKa1_Mmus      -------------------------------------------------------I----
SNF1_Scer        -------------------------------------------------------EL-A-
AMPKa2_Hsap      -------------------------------------------------------T----
AMPKa1_Hsap      -------------------------------------------------------I----
T01C8.1_Cele     -------------------------------------------------------T----
Snf1_Ddis        -------------------------------------------------------E----
1110_Tthe        ----------------------------------------------------------Y-
11543_Tthe       ------------------------KPNQYEDQF---------------------NL-TA-
20428_Tthe       -------------------------------------------------------LVNK-
21336_Tthe       ----------------------------------------------------------P-
26498_Tthe       NSYSLVNVQKYKVRKSKINSGLHNISNSIMSVN---------------------NAISN-
4451_Tthe        ----------------------------YVQSS---------------------TNHES-
7432_Tthe        QLPQSTKSVSGQLQQQQWQNKTQQQSPIHNNFFQEKKPKKQLTAQQKQLLINNKTQVQK-
27742_Tthe       ----------------------------------------------------------L-
AMPK_Spur        -------------------------------------------------------T----
aak-1_Cele       -------------------------------------------------------A----
CC1G_10117_Ccin  -------------------------------------------------------EL-AG
AqueK057_Aque    -------------------------------------------------------S----
AMPK_f_Smoe      ------------------------------------------------------------
AMPK_e_Smoe      -------------------------------------------------------E----
AMPK_a_Smoe      ------------------------------------------------------------
AMPK_d_Smoe      -------------------------------------------------------E----
AMPK_b-1_Smoe    -------------------------------------------------------E----
AMPK_b-2_Smoe    -------------------------------------------------------E----
AMPK_c_Smoe      ------------------------------------------------------------
GK014_Glam       -------------------------------------------------------H----
GK013_Glam       ----------------------------------------------------------G-
GK015_Glam       ----------------------------------------------------------K-


SNF1A_Dmel       --------------------------------LAR
AMPKa2_Mmus      --------------------------------LAR
AMPKa1_Mmus      --------------------------------LAQ
SNF1_Scer        -----------------------------VNSQSN
AMPKa2_Hsap      --------------------------------LAR
AMPKa1_Hsap      --------------------------------LAQ
T01C8.1_Cele     --------------------------------LAR
Snf1_Ddis        --------------------------------LNL
1110_Tthe        -----------------------------NRKQIY
11543_Tthe       -----------------------------SNEVND
20428_Tthe       -----------------------------KLNPIH
21336_Tthe       -----------------------------KKRQIF
26498_Tthe       -----------------------------HTKDKI
4451_Tthe        -----------------------------SSQVFR
7432_Tthe        -----------------------------RFLFDQ
27742_Tthe       -----------------------------PIQQKK
AMPK_Spur        --------------------------------LAR
aak-1_Cele       -------------------------------LLAE
CC1G_10117_Ccin  GGELVEGRGRGVVTEEVGCGGSRREKETGLRGDAM
AqueK057_Aque    --------------------------------LAQ
AMPK_f_Smoe      -------------------------------AGFA
AMPK_e_Smoe      -------------------------------LRVL
AMPK_a_Smoe      -------------------------------FWKH
AMPK_d_Smoe      -------------------------------LRVL
AMPK_b-1_Smoe    -------------------------------LRVL
AMPK_b-2_Smoe    -------------------------------LRVL
AMPK_c_Smoe      -------------------------------AGFA
GK014_Glam       -------------------------------FRAG
GK013_Glam       -----------------------------RSRLQK
GK015_Glam       -----------------------------GLKLKG