Protein (view, download) , Domain (view, download)
BIKE_Hsap        MKKFSRMPKSE---GGSGGGAAGGG---AGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLE
AAK1_Hsap        MKKFFDSRREQ---GGSGLGS--GS---SGGGG--STSGLGSGYIG-RVFGIGRQQVTVD
BIKE_Mmus        MKKFSRMPKSE---GSGGG-AAAGG---AAGGG--LGGGFASSSMGVRVFAVGRYQVTLE
AAK1_Mmus        MKKFFDSRREQ---GSSGLGS--GS---SGGGG--SSSGLGSGYIG-RVFGIGRQQVTVD
sel-5_Cele       MPLGLFSSGKA--QVLCD-EKIP-----GGKKK-EPKQLSENKCKG-VTLKLDHTRVTIE
DDB0229347_Ddis  MNRFLEFSNNFLEVAGNTINNISSKSITDNVGN--VWGNITGGRVG-QVYDINGRRVTEV
DDB0229350_Ddis  MG----------------------------------------NNQG-KTLKIGSYHLNFV
Nak_Dmel         MKKILSKFERN---ENSRLEN--PP---NSSSS--SSSNEKNSFVG-KVFTVGRVTVTVE
AKL1_Scer        MSITNGTSRSV---SAM------------------GHPAVERYTPG-HIVCVGTHKVEVV
ARK1_Scer        MNQP----------------------------------QIGTYNVG-TQLTVGSHQVEII
PRK1_Scer        MNTP----------------------------------QISLYEPG-TILTVGSHHAKII
AAK1_Spur        MV----------------------------------------------------------
AqueK170_Aque    MAELVRKRS-S---G---------------------RQRLRQGYVG-KTFTLDGRQYIVE
                 *

BIKE_Hsap        ESLAEGGFSTVFLVRTH---------------GGIRCALKRMYVN-NMPDLNVCKREITI
AAK1_Hsap        EVLAEGGFAIVFLVRTS---------------NGMKCALKRMFVN-NEHDLQVCKREIQI
BIKE_Mmus        ESLAEGGFSTVFLVRTH---------------SGIRCALKRMYVN-NTPDLNICKREITI
AAK1_Mmus        EVLAEGGFALVFLVRTS---------------NGVKCALKRMFVN-NEHDLQVCKREIQI
sel-5_Cele       KQIAEGGFAIVYVASDRK---------------NNKFALKRQFTKDNEKQLEACCREHSF
DDB0229347_Ddis  KLVAEGGFGFVYLVRDDY--------------N-NMYALKRMFIQ-ERERLEAMKNEIDV
DDB0229350_Ddis  KQIAEGGFSYVFLVKDSN--------------TSKHYALKRILIR-DEDELKGVKHEISI
Nak_Dmel         DVLAEGGFAMVFLARGNGGG----------SSSATKYALKRMYVN-NEHDLNVAKREIQI
AKL1_Scer        NYLAEGGFAQIYVVKFLEYLNEFDNTASVPLKIGDVACLKRVLVQ-DENGLNEMRNEVEV
ARK1_Scer        KYLTSGGFAQVYSALINPPD---------PHSNSSVACLKRVIVP-DKPSLNTLRAEVDA
PRK1_Scer        KYLTSGGFAQVYTAEISPPD---------PYSNANIACLKRVIVP-HKQGLNTLRAEVDA
AAK1_Spur        ------------------------------------------------------------
AqueK170_Aque    DVIAEGGYAIVLEVKCTA-------------GTNERLALKRVAVN-SEQDLYLCRQEIAI


BIKE_Hsap        MKELSGHKNIVGYLDCAVNSI-SD--NVWEVLILMEYCRAGQVVNQMNKKLQ--TGFTEP
AAK1_Hsap        MRDLSGHKNIVGYIDSSINNV-SSG-DVWEVLILMDFCRGGQVVNLMNQRLQ--TGFTEN
BIKE_Mmus        MKELSGHKNIVGYLDCAVNSI-SD--NVWEVLILMEYCRAGQVVNQMNKKLQ--TGFTES
AAK1_Mmus        MRDLSGHKNIVGYIDSSINNV-SSG-DVWEVLILMDFCRGGQVVNLMNQRLQ--TGFTEN
sel-5_Cele       LKQCIGHKNIVEFVDSYTNCL-GN--GIWECMLLTEYHQ-KNVLQLMNERISQNQYLTND
DDB0229347_Ddis  MQKLRNNPNIVKLEGFKINEN-RNT-RETEVLMLMEYCSGGSVLDIMNARGEF-TRLEER
DDB0229350_Ddis  MKRLTKHKNIVKILDYHKVS---DK-NNTEMFILMEYCSGGHLVEIMQKRLSSGSKFTDQ
Nak_Dmel         ASNLSGHKNIIGYVDSSITPT-GN--GVCEVLLLMPYCKH-HMLAMMNARLH--VGFTEP
AKL1_Scer        MKKLKGAPNIVQYFDSNASRR-RDGVQGFEVLLLMELCPNKSLLDYMNQRLS--TKLTEA
ARK1_Scer        MRLLKNNRYVVSYIDSHAAKAMLHN-GSYEVFVLMEYCERGGLIDFMNTRLQ--NRLHEF
PRK1_Scer        MKLLRNNKHVVSYIDSHAARS-VNG-IAYEVFVLMEFCERGGLIDFMNTRLQ--NRLQES
AAK1_Spur        --------------------------------------TDGHVVQQMNERLS--VGFTEQ
AqueK170_Aque    LKALSDSPNSVTYLASQINKL-SR--EVYEVLILMQLYGGQTGLQLIRQYHGQGKRLPEA
                                                            :  :.        : :

BIKE_Hsap        EVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLND--GGNYVLCDFGSATNKFLNPQ-
AAK1_Hsap        EVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHD--RGHYVLCDFGSATNKFQNPQ-
BIKE_Mmus        EVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLND--AGNYVLCDFGSATNKFLNPQ-
AAK1_Mmus        EVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHD--RGHYVLCDFGSATNKFQNPQ-
sel-5_Cele       EILSIFTDLCEAVSFIHNRPQPIIHRDLKVENVLISSHKPPHYVLCDFGSATTQILSVE-
DDB0229347_Ddis  EILAIFSDVCNGVLAMHQQQPPIAHRDLKIENVLYCE-HSNRYKLCDFGSSTIKTFNT-A
DDB0229350_Ddis  EILKIFQDICESVAYMHSQQPLIIHRDLKVENVLLDE-ESGIYKLCDFGSATEEITRMKN
Nak_Dmel         EVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTD--AGNFVLCDFGSATAKTLNPQ-
AKL1_Scer        EIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDA--KNNFKLADFGSTSTCFPIVTT
ARK1_Scer        EILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISA--NNEYKLCDFGSVCGIIRPPRN
PRK1_Scer        EILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISH--DGLYKVCDFGSVSGVIRPPRN
AAK1_Spur        EVLRIFCNVCEAVSRLHHCQTPIIHRDLKVENILLHR--SGNYMLCDFGSATGRVLDPK-
AqueK170_Aque    LILKIFTDVCLAVSRLHHRTKPIIHRDLKVTLLQM---------------------DPK-
                  :: *: :   .:  :*     : ***:*:  :

BIKE_Hsap        KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGES-
AAK1_Hsap        TEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-
BIKE_Mmus        KDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGES-
AAK1_Mmus        AEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGES-
sel-5_Cele       KYGVEYVKSEVERNTTMCYRSPEMIDFYSGLEIGLKSDIWALGVLLYRLCFFCVPFEES-
DDB0229347_Ddis  T-ERGKAEDDINMFTTLFYRAPEMVDLYRGQIIDEKVDVWALGCLLFKMAFYVDPFDGG-
DDB0229350_Ddis  KTEMQNAEDDISRHTTLQYRAPEIVDFYRSPVINEKIDIWALGCLLYKLLFYVTPFEDSG
Nak_Dmel         QHGVTVVQEEIQKYTTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPFGES-
AKL1_Scer        HQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTG
ARK1_Scer        SQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGG
PRK1_Scer        TQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSG
AAK1_Spur        VHSINDIKDEIEKYTTVSYRSPEMIDLYSEKTITTKADIWALGCMLYKLCFFTLPFGES-
AqueK170_Aque    EVGVGECQDQLQKFTTLAYRAPEMVDLYSGYTISTKSDIWALGCLLYKFCFFDTPFGEQ-
                          ::   **  **:**::: :    *  * *:**** :*::: ::  **

BIKE_Hsap        QVAICDGNFTIPD-NSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNI
AAK1_Hsap        QVAICDGNFTIPD-NSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNV
BIKE_Mmus        QVAICDGSFTIPD-NSRYSHNVHCLIRFMLEPDPECRPDIFQVSYFAFKFAKKDCPVSNI
AAK1_Mmus        QVAICDGSFTIPD-NSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNV
sel-5_Cele       PLAIQSVNYQFPS-VPNIPDEIKVLIYMLLDIDVNRRPSIYQTSVLAFEANHRKPLSEEI
DDB0229347_Ddis  SLQIINNNYKIPD-NSKYSNNFHKLIQFILVADPTQRPSINDLLNYLNEIRGSSRRGL--
DDB0229350_Ddis  SLGILNSNYTIPP-NHTHSNDLISLIKIMLNPDPINRPNIFEITNQLNLLRNQ-QPLFPS
Nak_Dmel         TLAIQNGQFSIPD-SSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNL
AKL1_Scer        QFAILHSKYEFPV-N-KYSSKLINLIIIMLAENPNLRPNIYQVLYHLCEILNVEVPIEDK
ARK1_Scer        DLAILSGKFEFPL-YPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNVPCPINDI
PRK1_Scer        EAGILHARYQYPS-FPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSRLQNKPCPIRNF
AAK1_Spur        SLAIQSGNFTIPD-NTKYSREMHALIRYMLEVDAEKRPDIFQVSHVAFKAASSETPIQNL
AqueK170_Aque    TLAIMRGTFSFPADASNYSNGLLGLIKYTLNTDPNKRPDIFQVSWVAYKLAGKDCPIVNV
                    *    :  *      .  .  **   *      **.: :

BIKE_Hsap        NNS------------------------------------------------------SIP
AAK1_Hsap        QNS------------------------------------------------------PIP
BIKE_Mmus        NNS------------------------------------------------------FLP
AAK1_Mmus        QNS------------------------------------------------------PIP
sel-5_Cele       QNKKCTDAV---------PSLKSCIQLMRDGSNP---RNKRDSSPRN-------------
DDB0229347_Ddis  ---QT--------------------FSSNNNNSN----NNSNNNSNNNSNNNSVNNSSNS
DDB0229350_Ddis  HKSNI--------------------LLSYNENNN---INNNNNNINNNNNNNIVNGKNIP
Nak_Dmel         HKT------------------------------------------------------PIP
AKL1_Scer        YAEGAYNFSKYTQFQNKLQNVQ--LQMYQLQQKKIMQNNKLSDSEENLLNDMFLSSFEIS
ARK1_Scer        QVV------------------------------------------------------QAP
PRK1_Scer        YLL------------------------------------------------------RAM
AAK1_Spur        HKS------------------------------------------------------PVP
AqueK170_Aque    FNS------------------------------------------------------PIP


BIKE_Hsap        SAL--PEPMTASEAA-ARKSQI-KARITD---TI--GPTE-TSI------------APRQ
AAK1_Hsap        AKL--PEPVKASEAA-AKKTQP-KARLTD---PI--PTTE-TSI------------APRQ
BIKE_Mmus        STL--PEPMTATEAA-ARKSQM-KARITD---TI--GPTE-TSI------------APRQ
AAK1_Mmus        AKL--PEPVKASEAA-VKKTQP-KARLTD---PI--PTTE-TSI------------APRQ
sel-5_Cele       -PE--APPIQSSSKM-ASLSQQ-VPSISNISMPSGSGTVE-TSV------------APRL
DDB0229347_Ddis  IN--RPIRTSS---------------------------------------------SSNS
DDB0229350_Ddis  KP--LPKVVSQTTPT--------------------P--TP-PPP------------APSQ
Nak_Dmel         NFDLLVVPPFESEAKRISAAAS-KAAKAQ-NVSV--VEAG-TSV------------APRS
AKL1_Scer        S--KLPMNA--SDGH-AAVSRIPSQNVGQE-L----EEEK-ESQSDQRKSTLSEDKSSRT
ARK1_Scer        SSH--LNLTELHQLS-A-------TQ------NI--L---SLNS------------P---
PRK1_Scer        NQN--ANTQLAGEPS-STTYV-PTQK----FIPV--QSLQSINQ------------PPNM
AAK1_Spur        DGNKLPLPLTESEQR-QQHSRS-KTNNQN-RTPAGPMEVS-TSV------------TPRQ
AqueK170_Aque    SVL--DMPMQLVKPK-ATKTLS-VSETTD-SNST--------------------------


BIKE_Hsap        RPKA-NS-AT-------------TATP-SVLTIQSSATPVKVLA-P----GEFGN---HR
AAK1_Hsap        RPKA-GQ-T--------------QPNP-GILPIQPALTPRKRAT-VQPPPQAAGS---SN
BIKE_Mmus        RPKA-NS-T--------------AATS-SVLTIQSSATPVKVPA-P----GEFSN---HK
AAK1_Mmus        RPKA-GQ-T--------------QPNP-GILPIQPALTPRKRAT-VQPLPQAAGP---SN
sel-5_Cele       RPKA-TT-V--------------VPNVPSISPVPPVGLPHLRLPSKGSTDETDGS---QV
DDB0229347_Ddis  TPNF-N-SPNTNNNNYNNNNNNS--KN-YGN--TPNST----------------------
DDB0229350_Ddis  SPSP-SPSPTVVNNIENNSNGLEHSNS-NGNISQPSPTPPKRRATPGTTPS-LQP---VS
Nak_Dmel         RPKG-SS-SVH------------GGNP-LGLGLPPSPSPRQNITSPQPQPQPVVEQFQAN
AKL1_Scer        TSNA-NS-SGT------------ANNPQEINTIQSPGIEDK----------SIFE---NK
ARK1_Scer        --TTMEN-T--------------MPN--ATFQISMADNTTTA-Q-M--------------
PRK1_Scer        MPVTHVS-T--------------TPNL-GTFPISINDNNKTEVT-AHAGLQVGSH---SN
AAK1_Spur        RPKA-SQ-QGV------------APAAGGISLPTPSSITRQRSS-KQGQPPTTGP---TV
AqueK170_Aque    ---------P-------------TPSP-SVM---------KRTTS-Q-QPT---------


BIKE_Hsap        PK----------------------------------------------------------
AAK1_Hsap        QP----------------------------------------------------------
BIKE_Mmus        PK----------------------------------------------------------
AAK1_Mmus        QP----------------------------------------------------------
sel-5_Cele       R-----------------------------------------------------------
DDB0229347_Ddis  -PPNAKKNIFDILGDDT-TSSTSNSNNSPSVSRNNINNNSNNFNNNNNNNNNNNNNNNNN
DDB0229350_Ddis  FPPNNSNNSFDDPFRDSPRT---------NLSNNPFNVNSNDNSNSSN-----NNNNNNN
Nak_Dmel         FP----------------------------------------------------------
AKL1_Scer        TP----------------------------------------------------------
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        L-----------------------------------------------------------
AAK1_Spur        AA----------------------------------------------------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ------------------------------------G------AL-----------RPGN
AAK1_Hsap        ------------------------------------G------LL-----------ASVP
BIKE_Mmus        ------------------------------------G------AL-----------RPGN
AAK1_Mmus        ------------------------------------G------LL-----------PSVS
sel-5_Cele       ------------------------------------K------VPIDFHHRQSFSGEEQL
DDB0229347_Ddis  NNNNNNNNTNNNNSNNNN--------YNNNN-----------------------------
DDB0229350_Ddis  NNNNNNNNNGNNITNEEILNIITQLTNNDQTNTFDSGLLLKLKSM-----------KPGK
Nak_Dmel         ------------------------------------A------MP-----------PAVP
AKL1_Scer        ------------------------------------G------EL---------YYPSVS
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        ------------------------------------A------AQ------------RLS
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        GPEILLGQGPPQQP-------------PQQHRVLQ----QL---QQGDWRLQQ---LHL-
AAK1_Hsap        QPK---PQAPPSQPLPQ-TQAKQPQAPPTPQQTPS----TQ---AQGLPAQAQ---ATP-
BIKE_Mmus        GSEVLMVQGPPQQP-------------PQQHRVLQ----QL---QQGDWRLQQ---LHL-
AAK1_Mmus        QPK---AQATPSQPLQS-SQPKQPQAPPTPQQTPA----TQ---TQGLPTQAQ---ATP-
sel-5_Cele       KPA---AEADSAGPLSC-PLIKPTDLGFTDLDKPA-------LPRDRAQTD---GKRRL-
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  GTMHIIVKRPLKEP-------------LVCFKSLLLVHALL---SEGNNIQFK---SD--
Nak_Dmel         PPP---QAVTPAAPAAS-KLFES-SGYPDPFNEPA----AAVIPTEFLPAAEEPNKEEV-
AKL1_Scer        E---------LDTYLDK-ELVKQSSDPTISEQSPR----LN---TQSLPQRQK---STSS
ARK1_Scer        --------------------------------HPN----RK---PSQIAYDAS---FSN-
PRK1_Scer        -----------T--------------------SPL----MK---TKSVPLSDE---FAS-
AAK1_Spur        PPQV-QAQQAIQQQ-------------QQQQQQQQ----QQ---QQQLLQEQQ---LAQ-
AqueK170_Aque    ---ITL---------TSISSRERPRSRPISSISPA----SS---SSY-------------


BIKE_Hsap        ------------------------------------Q---HRH-----------------
AAK1_Hsap        ------------------------------------Q---HQQ-----------------
BIKE_Mmus        ----------------------------------------HRH-----------------
AAK1_Mmus        ------------------------------------Q---HQQ-----------------
sel-5_Cele       ------------------------------------P---HES-----------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------V---HDSKDL--------------
Nak_Dmel         ------------------------------------P---QDL-----------------
AKL1_Scer        YSSGGRSMKSTSYGAATIGSDEALANEKTAGINKMKQ---HKSNNPFPKMNVAYHSTNEL
ARK1_Scer        -------------------------------------SAKGSQ-----------------
PRK1_Scer        ------------------------------------LYYKELH-----------------
AAK1_Spur        -----------------------------------QQ---NKQ-----------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ------PHQQQQQ---------------QQQQQQQQQ-----------------------
AAK1_Hsap        ------QLFLKQQ---------------QQQQQPP---PAQ---------------QQPA
BIKE_Mmus        ------PHHHHQQ---------------QQQQQQQQQ-----------------------
AAK1_Mmus        ------QHLLKQQ---------------QQQQQQPQQPTAP---------------PQPA
sel-5_Cele       ------DIIFQQQ---------------HRRNVSD--TSQI---------------SRSA
DDB0229347_Ddis  ------NKFDEFE-----------------------------------------------
DDB0229350_Ddis  ---FN-NLYLGWS---------------KQKDRYLQ------------------------
Nak_Dmel         ------NVIAGTPTKSMLTPPKPSGGGGHRRNVS--DTSAF---------------NK--
AKL1_Scer        SNDAS-NFFLEEQ---------------QQGQRYQQAQ-NQT------GT---QGNTFPD
ARK1_Scer        ------PL-FDKS-----------------------------------------------
PRK1_Scer        ------P--FQKS---------------QTFK----------------------------
AAK1_Spur        ----RLLALAQQQ---------------QQQQQQQQQQ--QQLAYNNAQAQAAYGPQQPQ
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ----QQQ--QQQQQQQQQQ-----------------------------------------
AAK1_Hsap        GTFYQQQQA------QTQQ-----------------------------------------
BIKE_Mmus        ----QQQ--LQQQQQQQQQ-----------------------------------------
AAK1_Mmus        GTFYQQQQQQQQQQAQTQQ-----------------------------------------
sel-5_Cele       FKPYSSQQT--TSKTSSQV-----------------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         -TFA--------------------------------------------------------
AKL1_Scer        ESQYQSRVEQQQQQQDQPKGPANYSQRNFYTGRDRSNKPMQLGGTIAGDSGNRRVNFQNI
ARK1_Scer        ---------------Q-NM-----------------------------------------
PRK1_Scer        ----SVES------FQSPQ-----------------------------------------
AAK1_Spur        QVAYAGQQG------FQQP-----------------------------------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        --------HHHHH-----------------------------------------------
AAK1_Hsap        --------FQAVHPATQKPAIA----------------------QFPVVSQG--------
BIKE_Mmus        ------------------------------------------------------------
AAK1_Mmus        --------FQAVHPAAQQPVTA----------------------QFPVGSQG--------
sel-5_Cele       --------VRSVEDMSQ-------------------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         ------------------------------------------------------------
AKL1_Scer        SQNYATNSQSGYLPSQNSPAIP---------------------MVRPVISMN--------
ARK1_Scer        --------YHALDPPLVEPLAS----------------------SV--SN----------
PRK1_Scer        --------RKSMPPLSLTPVNN----------------------DI--------------
AAK1_Spur        --------YQQPQPTPQQPAFGQHGAFTRPQQLTYEQQQASIQAQYAQQQAALQQQQQQA
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ---------HHHLLQDAYMQQY----QHA----------TQ-----------QQQML---
AAK1_Hsap        -------GSQQQLMQNFYQQQQ----QQQ----------QQQQQQQLATALHQQQLMTQQ
BIKE_Mmus        ------------LLQNAYLQQY----QHA----------MH-----------QQHIL---
AAK1_Mmus        -------GAQQQLMQNFYHQQQ----QQQ----------QQ-----------QQQLMAQQ
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ---------LGELLSHYSLLL---------------------------------------
Nak_Dmel         ------------------------------------------------------------
AKL1_Scer        -------QQQAQQIQAQQLQAQ----QMQ----------AKQQMQAKQQMQVQQQLQVQQ
ARK1_Scer        ----------------------------NDNELKANSATKL-----------KQAIVSEA
PRK1_Scer        -------------------------------FDRVSAINRP-----------NNYVDSET
AAK1_Spur        ALQQQQQAALQQQQQAAYQQQQQALLQQQ----------QQQQQQQQAAYLSQQAALEQQ
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ---QQQFLM-------------HSVYQPQP--------SASQ--YPTMMPQYQQAFFQQQ
AAK1_Hsap        AALQQKPTM-------------AAGQQPQP--------QPAA--APQPAPAQE--P-AIQ
BIKE_Mmus        ---QQQFLM-------------HSVYQPQP--------PASQ--YPAMMQQYQQAFLQQQ
AAK1_Mmus        AALQQKTAV--------------VVPQSQA--------QPAT--APQAAAAQE--PGQIQ
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ---YKFILFHQKNYMIDGSFAFEEMKWGIPESLDSNNHPISINTIKALFDIMDHLFLVQN
Nak_Dmel         ------------------------------------------------------------
AKL1_Scer        ------------------------------------------------------------
ARK1_Scer        HTFRQNNSI--------------D------------------------------------
PRK1_Scer        QTIDN---M--------------A------------------------------------
AAK1_Spur        AVLQQQQLAYQQQQQLAAQQQQYQASSP-P--------PFSQ--QPQFIPSEQQALYQQQ
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        MLA-Q-------------------------------------------------------
AAK1_Hsap        APV-R-------------------------------------------------------
BIKE_Mmus        MLA-R-------------------------------------------------------
AAK1_Mmus        APV-R-------------------------------------------------------
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  ----------------SWGNTPLQHP----SPSNSNS-N--VIIN---------------
DDB0229350_Ddis  NLSDYCINNICSSNSSGSGNVPISLLQHCVNILNSSSYSIFCFISGSIDVLSKQFSDVDM
Nak_Dmel         ------------------------------------------------------------
AKL1_Scer        ------------------------------------------------------------
ARK1_Scer        --------------------FPL-------------------------------------
PRK1_Scer        --------------------VPN-------------------------------------
AAK1_Spur        QAALQ-------------------------------------------------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        --------HQPSQ---------------QQASPEYLTSPQEF------------------
AAK1_Hsap        --------QQPKV---------------QTTPPP-AVQGQKVG-SLTPPSSPKTQRAGHR
BIKE_Mmus        --------HQQPA---------------QQVSPEYLTSPQEF------------------
AAK1_Mmus        --------QQPKV---------------QTTPPP-TIQGQKVG-SLTPPSSPKTQRAGHR
sel-5_Cele       --------RQNGG---------------S-------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  KLISCVNQFQSMY---------------TRLRE---------Q-YTKLAQ------VP--
Nak_Dmel         ---------------------------------------NET------------------
AKL1_Scer        ---------QMQI---------------QNAN----------------------------
ARK1_Scer        ------------QNIIPQYEDSSSSSDESYS-----------------------------
PRK1_Scer        ------------LKLSPTITSKSLSSTKEIAAPD-NINGSKIVRSL--SSKLKKVITGES
AAK1_Spur        --------QQQQQ---------------AQQQQQFLQAQ-----------A---------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ---SPALVSYTSSLPAQVGT---------------------IMD-SSYS-ANRSVADKEA
AAK1_Hsap        RILSDVTHSAVFGVPASKSTQLLQ--------A-------AAAE-ASLN-KSKSATTTPS
BIKE_Mmus        ---SPALVSYASSLPAQVGT---------------------IVD-SSYG-ANRSVAEKEA
AAK1_Mmus        RILSDVTHSAVFGVPASKSTQLLQ--------A-------AAAE-ASLN-KSKSATTTPS
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  -CFSDI---FFPTLPN----TAPT--------F-------TIVRSNSFNRLNSSLSDLNL
Nak_Dmel         ---SQFLAPFNNNL------AA-MGDGQQTLASAASNPGIYASS-TANS-AAVSIS----
AKL1_Scer        ----------------NNGT---------------------------YV-SDRTNHTTED
ARK1_Scer        -----------GDVDELKKTRSLG--------S---------------------------
PRK1_Scer        RGNSPIKSRQNTGDSIRSAFGKLR--------H-------GFTG-NSVN-NSRSAS----
AAK1_Spur        ----QALA--QAQAAGAVGT---------------------LVE-VDAA-DH--VSPVQD
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        IANFTNQKNISNPPDMSGWNPFGE--D-------------NFSKLTEEELLDREFDLLRS
AAK1_Hsap        GSPRTSQQNVYNPSEGSTWNPFDD--D-------------NFSKLTAEELLNKDFAKLGE
BIKE_Mmus        VANFTNQKTISHPPDMSGWNPFGE--D-------------NFSKLTEEELLDREFDLLRS
AAK1_Mmus        GSPRTSQQNVSNASEGSTWNPFDD--D-------------NFSKLTAEELLNKDFAKLGE
sel-5_Cele       ----------------GEWNPFLV--APFSNNSISRKDGQESAFMMDDSHFGMVFDEIRR
DDB0229347_Ddis  -------NTNS-----SGKNNQNKSNS-------------GNGNF---------------
DDB0229350_Ddis  -NNNNNNNNNS-----NNSNNSNN--S-------------NSGNLSGNASLNSSFDNINS
Nak_Dmel         --ELMKPGQTAVEKRVEAWNPFEE--E------------QPFSQMTEDHIFEAEFDKIRQ
AKL1_Scer        MRNAQ----GGEPPILAG-NSANE--PMHS-------------S-SKNEALLIELSPLKE
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        LA--------------SPTNPFSP--Q-----SAMLA--SQLPAPPDDEDLDSEFDQLRK
AqueK170_Aque    ----VSEQ----------------------------------------------------


BIKE_Hsap        NRLEERASSD---KNVDS-LSAPHNHPPEDPFGSVPFISHSGSPEKKA--EHSSIN----
AAK1_Hsap        GKHPEKLGGS-----AES-LIPGFQSTQGDAFATTSFS--AGTAEKRK--GGQTV-----
BIKE_Mmus        NRLGASTPSD---KTVDL-PPAPHSRPPEEPFASVPFISHSGSPEKKT--TEHSPN----
AAK1_Mmus        GKLPEKLGGS-----AES-LIPGFQPTQGDAFTTPSFS--AGTAEKRK--GGQAV-----
sel-5_Cele       KEIPAELD--SETS----------SIDSRDPFGAAPFDQLTVSTSSSA--QPVSLPPATD
DDB0229347_Ddis  ------FDND---FEFEG-FVSPTTNGSTNFEVNTTNTNVSLNSSTHS--SSSFNN----
DDB0229350_Ddis  SNP---FSTE---PTFNP-FSATTTNTSESGFGNFGLSEPTSNPSPRY--QQSNNN----
Nak_Dmel         RGSQGTAPGAVPPPPIAAAVSPYPSQVSEDPFGSAPFSLPPGLREKAS--SLRKTG----
AKL1_Scer        DAGKQS-FQDT---------NEPQTGGIEDAGGS--------------------------
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        VSPETATN--VAQPQIQGISNPP---HTTDVFGAVPFNLREGRPQSGGAAEMEQIA----
AqueK170_Aque    ---------------------------------------------KKP--P---------


BIKE_Hsap        -----------------------QENGTANPIKNG--K----------------------
AAK1_Hsap        ------------------------------------------------------------
BIKE_Mmus        -----------------------QKSITANLTKNG--G----------------------
AAK1_Mmus        ------------------------------------------------------------
sel-5_Cele       EDDERQLLSETDEEEKYEIDEKEEIQTKKDETINE--E----------------------
DDB0229347_Ddis  -----------------------SSNNNNTNNSSV--S----------------------
DDB0229350_Ddis  -----------------------NNNNNNNNGTPI--S----------------------
Nak_Dmel         -----------------------AKFIGVSSGGTGGGV----------------------
AKL1_Scer        -----------------------------------------------------------G
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        -----------------------SGTGSQQTLVQG--HVMESSPPLVGGEGEARKGGHMD
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ---TSPASKDQR------------------------TGKK-TS-----------------
AAK1_Hsap        ------------------------------------------------------------
BIKE_Mmus        ---SSPLCKDQR------------------------AGKK-TS-----------------
AAK1_Mmus        ------------------------------------------------------------
sel-5_Cele       ---DSEI-DEQR------------------------MNDRRRY-----------------
DDB0229347_Ddis  ---VG--SSI--------------------------------------------------
DDB0229350_Ddis  ---LTPGSLS--------------------------------------------------
Nak_Dmel         ---ATPIG--LVAGGANTATSSNSSKWMLSPTLEVSSEEK-TSLISKLKTDSECGIPGAV
AKL1_Scer        TI----------------------------------KGSN-NN-----------------
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------FDN---------------------------------------------------
AAK1_Spur        VFGATPFG-------------LSGGGQAAQPSQ---------------------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        -----------------------VQGQVQKGNDESE---SDF------------------
AAK1_Hsap        -----------------------------------D---SGLPLL---------------
BIKE_Mmus        -------------------ENPVIRGQVQKGHDDSE---SDF------------------
AAK1_Mmus        -----------------------------------D---SGIPLL---------------
sel-5_Cele       -------------------SYENIDG----VGDDAS---SD-------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         GGAGEGVSGYVKLPVEDRNKYEKLRSKDQPTSDDSD---SEASEFFQQDSDEGGGGIFRQ
AKL1_Scer        -------------------------RNGVLNLSLN-------------------------
ARK1_Scer        ---------------------YSTRGNIKKNQSVKESLTS--------------------
PRK1_Scer        ---------------------NNVNGNGNNT---NRRLVS--------------------
AAK1_Spur        ----------------------TTQQQQQRHMSPQE------------------------
AqueK170_Aque    -------------------------------NNMVQ---SS-------------------


BIKE_Hsap        ------------------------------------------------------------
AAK1_Hsap        ------------------------------------------------------------
BIKE_Mmus        ------------------------------------------------------------
AAK1_Mmus        ------------------------------------------------------------
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         MQMVTSNLPETIHKIQQVAYHKVDKTAHLPIVKKLRDKTKKPTTAAHQAAQQLNLMAAAV
AKL1_Scer        ---------------------------------------------------EMDLS----
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        ----------------------------------------------------ADLLGAMA
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        -----------------------------------------------------------E
AAK1_Hsap        ----------------------------------------------------------SV
BIKE_Mmus        -----------------------------------------------------------E
AAK1_Mmus        ----------------------------------------------------------SV
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         AAQAEEAAK------------------------------------------------AAE
AKL1_Scer        ---------------------------RDDTGAAVSSFSSSSSSAS-------------I
ARK1_Scer        ---------------------------------------SSLPG---------------T
PRK1_Scer        ---------------------------------------SS--T---------------S
AAK1_Spur        TEPQPESASTPRIRVGFEDDFVREGKQEGRSER---LTSTGSSSGGFNLERSIRELDEFG
AqueK170_Aque    -----------------------------------------------------------F


BIKE_Hsap        SDPP----------SPKSS-EEEEQDDEEVLQGEQGD--FNDDD--------T-----EP
AAK1_Hsap        SDPF----------IPLQV-PDAPEK---LIEGL--------------------------
BIKE_Mmus        SDPP----------SPKSS-EEEQEDED--AQGEHGD--FNDDD--------T-----EP
AAK1_Mmus        SDPF----------IPLQV-PDAPEK---LIEGL--------------------------
sel-5_Cele       SRGK----------TDRDD-SEEEEDDDS-RR--GGDTSHDEDS--------QNTVGSED
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         SDGD----------SIGSA-SD--------LRAEDDD-LFDENP--------R-----QT
AKL1_Scer        QQAKLSGRKGSSKR-NNYS-TDELG-DSM-VSSESID--IDLDD--------A-----RR
ARK1_Scer        SFTP----------TSTKVNLK--------------------------------------
PRK1_Scer        SFPK----------FNSDTKRKEESDKNQRL-----------------------------
AAK1_Spur        AKPF--GSVRQHRGSESSS-D----HEGERLSSSLRD--FSYDTFDSDSIDIR-----KD
AqueK170_Aque    KDPL----------P---------------------------------------------


BIKE_Hsap        ENLGHRPLLMDSEDE----------------------EEEEKHSSD-SDY----EQAKAK
AAK1_Hsap        ------------------------------------------------------------
BIKE_Mmus        ENLGHRPLLMDSEDE----------------------EEDDKHSSD-SEC----EQAKTK
AAK1_Mmus        ------------------------------------------------------------
sel-5_Cele       GEGGSRPLLEDDGLE----------------------D-DDDHELI-SSF----SSS---
DDB0229347_Ddis  NNSGTRLMNNSSGSLP------QSRQ--SSFN-----------STP-QQ-Q----QQQFN
DDB0229350_Ddis  PVIGAK-----KPPLPPNIHHLQQQQHPQQQQQQQQQQQQQQQQQQ-QQQQ----QQQQQ
Nak_Dmel         QAKQRRPLPTEMDGI----------------------SESVKTCSS-SAYHAECESVTTH
AKL1_Scer        GKTAERRPLHNERGH----------------------K-DQARSSDASKS----NQFKSK
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        EEHAHRGLLDQEESS----------------------EDESDD-----------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        YSDMSSVYRDR-SGSGPTQDLNTILLTSA--------QLSSDVAVETPK--QEFDV-FGA
AAK1_Hsap        --------------KSP----DTSLLLPDLLPMTDPFGSTSDA--VIEK--ADVAV-ESL
BIKE_Mmus        RGDTSSLRRDK-PGVAP----DTALLTPA--------RSPADA--LTPS--QEFDV-FGA
AAK1_Mmus        --------------KSP----DTSLLLPDLLPMTDPFGSTSDA--VIDK--ADVAV-ESL
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  SSTNSGSYNNL-TSS---------------------------------------------
DDB0229350_Ddis  HPQQQGLRFPH-SASLEDAR----------------------------------------
Nak_Dmel         EDDVRSRVVVKVRMRKKD----RALVTAT-----GDPSAPSEE--LSPTSSDLLHK-FGD
AKL1_Scer        --DFSSV------------------------------------STRQPR--QSLDLNFQE
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        -----------------------------------------------DSDHHDFDE-VGA
AqueK170_Aque    ------------------------------PPPT--------------------------


BIKE_Hsap        VPFFAVRAQQP--QQEKN-EKNLPQHRFPAA-----------GLEQEEFDVFTKAPFSKK
AAK1_Hsap        IPGLEPPV----------------------------------------------------
BIKE_Mmus        VPFFAAPAPQS--LQHRGDGKNLSQHAFP---------------EQEDFDVFTKAPFNKK
AAK1_Mmus        IPGLEPPV----------------------------------------------------
sel-5_Cele       -----------ST-------------NYPPLFIGTST----PHTQNPITNP---------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         RPLLLDDELDYGSGESKS------STESPVAPI----LPTNPDVQESEEDVFALAPFKLP
AKL1_Scer        VNLS--------------------------------------------------------
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------EKRRSMPPSILSDFDQHERNNS-----RTG
AAK1_Spur        QPLIGDDGHGLSDAELASL-NL--HEDLPSQKVRKSEPPVAQLIDMTDDDPFSQAPFKAK
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        VNVQECHAVGP---EAHTIPGYPK------------------------------------
AAK1_Hsap        ------------------------------------------------------------
BIKE_Mmus        VSVQDWPAVGP---DARPLPARPR------------------------------------
AAK1_Mmus        ------------------------------------------------------------
sel-5_Cele       -----------F----LRDELTPKMIITAPLPTAKNNLDDDWDLGDRWTDRRDTVFERP-
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         VGVPLKRKTKP---KAKPKPSEPEMWTSTPVKSAAV--------GDPS-----TNF----
AKL1_Scer        ------------------------------------------------------------
ARK1_Scer        ------H-----------------------------------------------------
PRK1_Scer        SRDY-YR-----------------------------------------------------
AAK1_Spur        TGS-LKRATEPVGMCALTPPISPPMQEEDPFGEAPF--------N-PR-----SGFERET
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ------------------------------------------------------------
AAK1_Hsap        ------------------------------------------------------------
BIKE_Mmus        ------------------------------------------------------------
AAK1_Mmus        ------------------------------------------------------------
sel-5_Cele       -----ASEHQNVFAPATLPRQATPLVCRFKPDLPTAAPVSIIPSMSNT------------
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ------------------------------------------------------------
Nak_Dmel         ----------------------------------ASFPAQ-LTPTNNVGNSA--------
AKL1_Scer        ----------SPTLTQEHR-----------------------------------------
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        SKSSVGSTGS---------------------DVFSKAPFL-VSSKKRQGTGSEVRRAKTQ
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        --SVD--VF--GSTPFQPFL-----TSTSKSES----NEDLFGLVPFDEITG--SQQ---
AAK1_Hsap        ------------------------------------------------------------
BIKE_Mmus        --SVD--IF--GSTPFQPFS-----VSASKSES----KEDVFGLVPFEEITG--SQQ--Q
AAK1_Mmus        ------------------------------------------------------------
sel-5_Cele       ----------------------------SFPEA----VRDS-DTVPCEPII--GTLI--S
DDB0229347_Ddis  ---------------FNNLN-----ISTSS------------------------------
DDB0229350_Ddis  ---------------LYTLI-----LTPSS------------------------------
Nak_Dmel         --QLD--EF--NEPIFNPFQ-----ENAQNTQSGETNQCDLFGLEPFPQVIR--TIE---
AKL1_Scer        ---------NK-------------------------------------------------
ARK1_Scer        -----------ENSPFKSTF-----VNT-IDNS----KDDLN-KPSYEDLDV--SKQNLK
PRK1_Scer        -----------SHSPVKKTQ-----ASA-KTTS----KPTLI--PDNGNVNI--N-QEKK
AAK1_Spur        HVSGEQTALGNPTPPISPTELGAQGVSSKMSKQ----EPDMFGAVPFHAVASHGSDL--E
AqueK170_Aque    ---------------------------------------DL-------------------


BIKE_Hsap        QKVKQRS-------LQK----LSSRQRR-TKQDMSKSNGKRHHGTPTS------------
AAK1_Hsap        --------------PQR----LPSQTE---------------------------------
BIKE_Mmus        QKVKQRS-------LQK----LSSRQRR-TKQDVSKSNGKRHHGTPTS------------
AAK1_Mmus        --------------AQR----LPSQTE---------------------------------
sel-5_Cele       V--GAPTDPPPPPLPKKPTEASPTQET------------------TAT------------
DDB0229347_Ddis  ------------------------------SASIS-SSGGVSNNSDNS------------
DDB0229350_Ddis  ------------------------------SPPLSPSTGPTTAAQQQQQQQQSQHTFDNF
Nak_Dmel         QNPQHHQ-------IHQ----FPSHNNN---NNVIKVPASVSVALPAS------------
AKL1_Scer        -------NDSPAPNSHHSYRVSPHAST---------------------------------
ARK1_Scer        NSIQQRM-------IDK----LNSSEESFN-----------------A------------
PRK1_Scer        ESIQRRV-------HNL----LKSSDDPVTYKSASGYGKYTDIGTETS------------
AAK1_Spur        MSSKEDA----------------------------QQPGPASHKRPHV------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        ---TK-K--TLKPT---------------YRTPERARR------HKK-VGRRDSQSSNE-
AAK1_Hsap        -----------------------------------------------------SVTSNR-
BIKE_Mmus        ---AK-K--TLKPP---------------YRTPERARR------HKK-VGRRDSQSSNE-
AAK1_Mmus        -----------------------------------------------------SVTSNR-
sel-5_Cele       ---IP-VALGKKEK---------------LLKKE-KKK------EKK-DGKKDKLKLEE-
DDB0229347_Ddis  ---WN-V--TLTPS---------------QSNKNSTGNLKPLNNNNNNNNNNNNRF--AN
DDB0229350_Ddis  NINGH-A--PPVPQ---------------STQPSFQPHVSF-APNVNINNNNNSHVSAPH
Nak_Dmel         ---VP-V--SVSVNSSAPQLVTINHSIIINKTPEPPMN------YNN-NNNNQTAKSSG-
AKL1_Scer        -----------------------------------------------------AITENK-
ARK1_Scer        ---RKMS--KVKL-----------------------------------------------
PRK1_Scer        ---NRHS--SVRIT---------------PITEEKFKK----------------------
AAK1_Spur        ---VS-TAVGVRRS---------------SRTSSGGRR-------RR-SGSNSSRSSRR-
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        -FL--------TISDSKEN--ISVA-LTD---GK-DRGNVLQP-EESLLDPFGAKPFHSP
AAK1_Hsap        -TDSL------TGEDSLLD--CSL--LSN-------------P-TTDLLEEFAPTAIS--
BIKE_Mmus        -FL--------TISDSKEN--ISVA-LTD---GK-DRASVLPS-DESLLDPFGAKPFHPP
AAK1_Mmus        -TDSL------TGEDSLLD--CSL--LSN-------------P-TAGLLEEFAPIALS--
sel-5_Cele       -YR--------EKGSSEPETDGSEA-EIW---TN-DGATTFSN-KKKKKSTF--------
DDB0229347_Ddis  NTNSSRDYSFDF----SSP--N--T-SNN----N-DFGSFVQPSSSSSLNT---THFSKP
DDB0229350_Ddis  SLNSSS----------SSI--S--S-ISN----P-NLGGIAQKGSGNSLMP---PPLYKP
Nak_Dmel         -TSSVYVNVPSFSSMSTSS--C--S-INQ---PQSSPAAVIPV-QAPLPVPV-PAPVSVP
AKL1_Scer        -RHST------GHE-------LST--RS--------------------------------
ARK1_Scer        ------------HEKGEID--KPTMLKSSGPISK-DKK----------------------
PRK1_Scer        -----------TLKDGVLD--IKT--KSN---GK-DKS----------------------
AAK1_Spur        -SS-----------SSSAS--NSLK--SS---PGSQP--RLRG-SQDSLDAFGSRPFSLA
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        -------------------------------------DLS------------------WH
AAK1_Hsap        -----------------------------------------------------------A
BIKE_Mmus        -------------------------------------DL-------------------WH
AAK1_Mmus        -----------------------------------------------------------A
sel-5_Cele       ------------------------------------------------------------
DDB0229347_Ddis  -------------------------------------NYNVNLN----------------
DDB0229350_Ddis  -------------------------------------AARGHRRSQSSNGDEVRRRNLLQ
Nak_Dmel         AVPVPIPAVVTHLRPLLPIADNAYVQISQDRCSDFTPDDE------------------EE
AKL1_Scer        ------------------------------------------------NGKHETHRTG--
ARK1_Scer        ------------------------------------------------------------
PRK1_Scer        ------------------------------------------------------------
AAK1_Spur        -------------------------------------DD---------------------
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        PPHQGLSD--IRADH--------------------NTVLPGRPRQNSLHGSFHSADVLKM
AAK1_Hsap        PVHKAAED----------------------------------SNLISGFDVPEGSDKVAE
BIKE_Mmus        QPHQGLSD--ICVDH--------------------TTILPGRPRQNSVHGSFHSAETLRM
AAK1_Mmus        PTHKAAED----------------------------------SNLISGFGVAEGSEKVAE
sel-5_Cele       ----------------GLRSS---------------------------------HPSIVA
DDB0229347_Ddis  ---QTTSMTNNYNNN--------------------NY--------NNNNNSNNNN-----
DDB0229350_Ddis  ---QQLEQNRDFLNH--------------------NRLLNKQSRMNNPNNLFDEGDS---
Nak_Dmel         PVVLRDAD--VVADGIGIPTPAKPKKEKSNLA---VRVLPGKLTQKVKGHSYKKVS---A
AKL1_Scer        ------------------------------------------------------------
ARK1_Scer        --------------------------------------TKPTPPPKPSHL---KPKPP--
PRK1_Scer        --------------------------------------RPPRPPPKPLHL---RTEIQKI
AAK1_Spur        ---------------------GQPKPVDTKLTFEDTFGRKLTPPQS--HKQLVLPLTKAV
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        DD--FG-AVPFTELVVQSITP---------------------------------H---QS
AAK1_Hsap        DE--FD-PIP--VLITKNPQG---------------------------------G---HS
BIKE_Mmus        DD--FG-AVPFTELVVQSVTP---------------------------------------
AAK1_Mmus        DE--FD-PIP--VLITKNTQG---------------------------------G---HS
sel-5_Cele       NDLQFSSPMP--PVVKKSSK--------------------------------------DK
DDB0229347_Ddis  ------------------------------------------------------------
DDB0229350_Ddis  ---------------------------------GFG------------------------
Nak_Dmel         AA--LG-ST--SSLSSGSKQKHQRLQYQSHDDDDDEQDQDE------N-RGAGGGRNFQS
AKL1_Scer        -----------------SKQRHDLERYRHSKDK-------------------------DS
ARK1_Scer        -----------------PKPL---------------------------------L-----
PRK1_Scer        RN--FS-RLQSKKLPIERISS---------------------------------E---AT
AAK1_Spur        DD--FG-AQPFTSPDSPA-AP---PAGFDVDVDPFGAAPFKPPAISGPVKRQG-AR--RA
AqueK170_Aque    ------------------------------------------------------------


BIKE_Hsap        Q---QSQPVELD-----PFG----------------------------------------
AAK1_Hsap        RNSSGSSESSLPN-LARSLL----------------------------------------
BIKE_Mmus        Q---QSQPVELD-----PFG----------------------------------------
AAK1_Mmus        RNSSGSSESSLPN-LARSLL----------------------------------------
sel-5_Cele       KSSLTGKNASFVN-TSFQPE----------------------------------------
DDB0229347_Ddis  -----------------NNS----------------------------------------
DDB0229350_Ddis  -----------------DGE----------------------------------------
Nak_Dmel         NTIQNSAKTGFSN-MSFEDFPSDQEMDRLSRTIPFEVVRNEKMLLEAEKKFGS------L
AKL1_Scer        -NSSITISTSTPSEMRKSF-------ARARQSLDLERVRREAMASSASSSGGSNGKRRSF
ARK1_Scer        ------------------L----------------------------------------A
PRK1_Scer        E---TIVDVNVD-----DL-------------------------------------EADF
AAK1_Spur        RESPGDEKSPEKM-SLASRQ----------------------------------------
AqueK170_Aque    ------------------F-----------------------------------------


BIKE_Hsap        AAPFPSKQ
AAK1_Hsap        LVDQLIDL
BIKE_Mmus        AAPFPSKQ
AAK1_Mmus        LVDQLIDL
sel-5_Cele       DHDDPTDL
DDB0229347_Ddis  KVFDFGIL
DDB0229350_Ddis  EEDEGLLN
Nak_Dmel         KRRNNLFS
AKL1_Scer        FSVFRSEK
ARK1_Scer        GRKLSLDK
PRK1_Scer        RKRFPSKV
AAK1_Spur        RRSFQTDL
AqueK170_Aque    ---GQAPF