kin-22_Cele ------------------------------------------------------------
Src42A_Dmel ------------------------------------------------------------
FRK_Mmus ------------------------------------------------------------
FRK_Hsap ------------------------------------------------------------
Frk_Spur ------------------------------------------------------------
AqueK408_Aque ------------------------------------------------------------
AqueK409_Aque ------------------------------------------------------------
AqueK410_Aque ------------------------------------------------------------
AqueK411_Aque MSKARVDDHYLYQWIKDSSLLVNDIHTQSSRQTQASKSSSTSSPNLQSMVTMYLLHAKYL
AqueK412_Aque ------------------------------------------------------------
kin-22_Cele --------------------------------------------------MGSC------
Src42A_Dmel --------------------------------------------------MGNC------
FRK_Mmus --------------------------------------------------MGSVCVRLWA
FRK_Hsap --------------------------------------------------MSNICQRLWE
Frk_Spur ------------------------------------------------------------
AqueK408_Aque --------------------------------------------------MGCK------
AqueK409_Aque --------------------------------------------------MGCC------
AqueK410_Aque --------------------------------------------------M---------
AqueK411_Aque DYSVQSDCSGLDSGSSLKLVECEVQLTVLDWTLRLSIADTTHSFWRIYRAMGCC------
AqueK412_Aque --------------------------------------------------MGCC------
kin-22_Cele ---------IGKEDPPP-GATSPVHT-S-STLG---------------------------
Src42A_Dmel ---------LTTQKGEPDKPADRIKLDDPPTIG--------------------VGVGVPQ
FRK_Mmus YLQPFLPCWSQEADKS-VVI--E-----------------------------NPG-----
FRK_Hsap YLEPYLPCLSTEADKS-TVI--E-----------------------------NPG-----
Frk_Spur ------------------------------------------------------------
AqueK408_Aque ---------GSKTSGD-NAVRAKEVTD-------------------------GKG--IPY
AqueK409_Aque ---------ASKATND-ENTTNKNTTDG-NNVGGGGGGTG-GIVGS----------GVDA
AqueK410_Aque ------------------------------------------------------------
AqueK411_Aque ---------SSNDSATSNKYKAKNSSDG-PGFS-------------------GPGSMGPP
AqueK412_Aque ---------ASAPEQP-RKKSNSMSYT---NQGGGGGGVPVGGANSYQPKPMNPGGYPPS
kin-22_Cele ----RESLPSHP---------------RIPSIGPIAA--SSSGNTIDKNQNISQSANFVA
Src42A_Dmel I--PMPSHA-G----------------QPPEQIR-PV--P--QIP-ESETAGANAKIFVA
FRK_Mmus --------------A-----------FCPPE-----A--P--R---SQEPERSHGQYFVA
FRK_Hsap --------------A-----------LCSP-------------------QSQRHGHYFVA
Frk_Spur ----------------------------------------------------------VA
AqueK408_Aque QTQANQLSPQGHGGF-----------VQDPRFQG-NI--P--QPQPTRIEQEPNYPVYVG
AqueK409_Aque RYHPNPQ----------------------PTVSL-S---G--NNNQNTSSVASSGPKFIA
AqueK410_Aque ------------------------------------------------------------
AqueK411_Aque ----RQSYPAGPPGDF----------SRQGSFGR-THNTG-LGYSGNQTASPPRGPVYIA
AqueK412_Aque AAYPSSAAPRGPPGYNMGGPPQIGGGAMVPQVGG-AV--P--HIGGGTMGGARSALMFIG
kin-22_Cele LFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATG-------RTGYIPSNYVAREK
Src42A_Dmel LYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTR-------SEGYIPSNYVAKLK
FRK_Mmus LFDYQARTAEDLSFRAGDKLQVLDTSHEGWWLARHLEKKGTGLGQQLQGYIPSNYVAEDR
FRK_Hsap LFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDR
Frk_Spur LFDYEARTQDDLGFKKGEELEVQND-SGDWWLARSRLTG-------LEGYIPCNYVAKVQ
AqueK408_Aque KYDYDSRTDDDLSFKKGNLLYIISTDEGDWWFARSKDTG-------KEGYIPSNYVAEYK
AqueK409_Aque RFKYMARTAEDLSFQKGERLVVIGPLEGDWWMARSLATG-------SEGYIPRNYVAPIE
AqueK410_Aque ------------------------------------------------------------
AqueK411_Aque LFDYDQRTSEDLSFRKGERLEILNDQDGDWWQAKSLDTG-------KEGYIPSNYVAEYK
AqueK412_Aque LYRYEARTPEDLSFDKGDQLQIMNNSDGDWWLARSLRTG-------REGYIPSNYVAAME
kin-22_Cele SIESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVRENDSVKHYRIRQ
Src42A_Dmel SIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQ
FRK_Mmus SLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEGVVKHYRIRR
FRK_Hsap SLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKR
Frk_Spur SLESEPWFFGSIKRMDAEKKLLLSQNEHGSFLIRESESRVGDYSLSVRDGDTIKHYRIRQ
AqueK408_Aque SLDAEEWYFGKLKRNEAEKQLMMPYNDYASYLVRDSETTPGDFSLSVRDTNRVRHYKIRR
AqueK409_Aque SYEAEDWYFGDIARAEAEKLLMISTNVQGTFLLRISSSQKDALSLSLRDVDGVKHYRIRK
AqueK410_Aque ---FLMWYFGKIKRVDAEKLLQLPINEVGAYLIRDSETNPGDYSLSIRDLERVRHYKIKR
AqueK411_Aque TIQAEDWYFGPIKRAEAEKL-LRATTMRGTFLVRESESKPGDYSLSIQDIETVKHYRIRK
AqueK412_Aque SVQAQDWFFGKIKRSDAEKKLLQIGNQSGTYLIRESESQPGNYSLSVRDGESVKHYRIRK
*:* : * :*** . .::*:* *.: ***: : ::**:*::
kin-22_Cele LDHGGYFIARRRPFATLHDLIAHYQREADGLCVNLGAPCAKSEAPQTTTFTY--DDQWEV
Src42A_Dmel LDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEI
FRK_Mmus LDEGGFFLTRRKVFSTLNEFVNYYTTTSDGLCVKLEKPCLKIQVPTPFDLSYKTADQWEI
FRK_Hsap LDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQWEI
Frk_Spur LDEGGYFIARRCTFATLVELVQHYQRDADGLCVNLRRPCVLIEKPQTRGLSYNTVDQWEI
AqueK408_Aque LDDGSFFVTRRVQFATIPELIMFYQRQADGLCTILKTPCRAVEKPQTAGLSRQANEEWEI
AqueK409_Aque MDDGGFFITTRAVFNTLQEMVRHYMMEADGLAQRLSVPCPRVNQPSTIGLSY--RDEWEI
AqueK410_Aque LDNGTFFITRKATFNTISELVSYYQRQADGLCSHLVKPCIEPEKPQTAGLSHAANEDWEI
AqueK411_Aque LDEGGFFITRRAVFNTLKELVEYYMKDSDGLCCMLRSACTQIEKPQI-DLSHKVKDMWEI
AqueK412_Aque VDSGGCYIAPRAMCKSLDDLVNHYKREADGLCCRLTVPCPKSDKPVTGGLSYNTKDEWEI
:* * ::: : :: ::: .* :***. * .* : * :: : **:
kin-22_Cele DRRSVRLIRQIGAGQFGEVWEGRWNVNVPVAVKKLKAGTADPTDFLAEAQIMKKLRHPKL
Src42A_Dmel DRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKL
FRK_Mmus DRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKSLRHPKL
FRK_Hsap DRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKL
Frk_Spur PRSSLQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLKxx----------------------
AqueK408_Aque DRQQVKLLRRLGAGQFGEVWEGLWNGTTQVAVKTLKTGTMSPQEFLQEAALMKRLRHPKL
AqueK409_Aque DRSTLQFNKKLGQGNFGEVWSGLWNETTPVAIKTLKPGTMEVNDFVKEAQVMKKIHHPHL
AqueK410_Aque DRRTIQMKRRLGAGQFGEVWEGLWNGTTQVAVKTLKPGTMSPQEFLQEAGLMKKLRHPKL
AqueK411_Aque PRESITLLRLLGTGQFGEVYEGLWNNTTPVAVKTLKTGTMQPQAFLEEAHIMKKLRHPKL
AqueK412_Aque ERTSLRLINRLGAGQFGEVWEGLWNNTTSVAVKTLKIGTMSVEDFLSEAQIMKKLRHEKL
* : : * *:**:*:.* ** .. **:*.**
kin-22_Cele LSLYAVCTRDEPILIVTELMQE-NLLTFLQR---RGRQCQMPQLVEISAQVAAGMAYLEE
Src42A_Dmel IQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLES
FRK_Mmus IQLYAVCTLEDPIYIITELMRHGSLQEYLQN--DGGSKIHLIQQVDMAAQVASGMAYLES
FRK_Hsap IQLYAVCTLEDPIYIITELMRHGSLQEYLQN--DTGSKIHLTQQVDMAAQVASGMAYLES
Frk_Spur ---------------------------------xKGHSLQLRILIDMSAQVAAGMAYLES
AqueK408_Aque IQLYAVCTKQDPIFIITELMKHGSLLDYLRA---DGRSLQQAQLIDMCAQVAAGMAYLEQ
AqueK409_Aque LQLYAVCTLEEPIYIVTELMSHGSLLDYLRN--GKGRYVNVHQMIDMIAQISSGMAYLEE
AqueK410_Aque IQLYAVCTEEEPIYIITELMKHGALLDYLRG---DGRSLQQAQLIDMCAQVAAGMAYLEQ
AqueK411_Aque IQLYAVCTKEDPIYIITELMPKGALLSFLQS--SEGRRLQLPQLIDMAAQIAAGMAYLEM
AqueK412_Aque IQLYAVCTQEEPIYIVTELMKNGSLLDYLQK--GAGRHLKLPELIDIGAQVANGMAYLEA
* : ::: **:: ******
kin-22_Cele MNFIHRDLAARNILINNSLSVKIADFGLARILM--KENEYEARTGARFPIKWTAPEAANY
Src42A_Dmel QNYIHRDLAARNVLVGDGNIVKIADFGLARLIK---EDEYEARVGARFPIKWTAPEAANY
FRK_Mmus QNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRT
FRK_Hsap RNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRS
Frk_Spur QNYIHRDLAARNVLVGENNICKVADFGLARVIK---DEIYESHVGAKFPIKWTAPEAANY
AqueK408_Aque QNYIHRDLAARNILVGEHLICKVADFGLARVID---EDIYEAHTGAKFPIKWTAPEAAMY
AqueK409_Aque HSYIHRDLAARNILVGEGNSCKVADFGLARVIK---EDIYSPKEGAKFPIKWTAPEAALY
AqueK410_Aque QNYIHRDLAARNILVGEHLICKVADFGLARVID---EDIYEAHTGAKFPIKWTAPEAAMY
AqueK411_Aque HNYIHRDLAARNILVGENNICKVADFGLARLIA---DDEYNAHEGAKFPIKWTAPEAALY
AqueK412_Aque QHYIHRDLAARNVLVGEGNIVKIADFGLARLIN---DDEYCAREGAKFPIKWTAPEAALY
:*********:*:.: *:*******:: :: * .: ::*:*******
kin-22_Cele NRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQ
Src42A_Dmel SKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIML
FRK_Mmus NKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIML
FRK_Hsap NKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIML
Frk_Spur HSFTIKSDVWSFGILLTEIITYGRIPYPGMTNKEVLDCVDRGYRMPNPPGCPPELYEIML
AqueK408_Aque NRFTIKADVWSFGIVLYEVITYGRFPYPGMTNAEVLEKLPQGYRMGCPTSCPKELHDVML
AqueK409_Aque SRFTIKSDVWSFGVLVAEVVTKGAMPYPGMTNRQVLESVEAGYRMPKPDTCPDPLYSIMM
AqueK410_Aque NRFTIKADVWSFGIVLYEVITYGRFPYPGMTNAQTLEAIQQGYRMPPPQNCPDKLYSVML
AqueK411_Aque NRFSIKSDVWSFGVLLTELVTYGRIPYPGMSNAEVLQQLERGYRMPCPPNTHESLYQIML
AqueK412_Aque SRFSIKSDVWSFGILLVELITHGRIPYPGMTNGEVLAKVEQGYRMPVPPGCPEPLYQIML
*: *:******::: *::* * :**.**:. :.: : .**: * ::.:*
kin-22_Cele QCWRSDPDKRPTFETLQWKLEDLFNLDSSEYKE-A-SINF
Src42A_Dmel ECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKE-A-Q-AY
FRK_Mmus ECWNVEPKQRPTFETLHWKLEDYFETDCS-YSDTN-NFIN
FRK_Hsap ECWNAEPKERPTFETLRWKLEDYFETDSS-YSDAN-NFIR
Frk_Spur ECWKSKAMERPTFETLQWKLEEFFVMEGEQYRE-A-SSIR
AqueK408_Aque ECWREDPSNRPTFESLQWRLEEFYTSTEGGYRE----PEP
AqueK409_Aque ECWRHEPDDRPTFESLKYRLDDYYVSAAEGSYQ-Q--NVQ
AqueK410_Aque DCWREEPETRPTFETLQWQLEEFYSTDDGGYRDPEQQPFR
AqueK411_Aque DCWKRNPADRPTFEALQWRLEDFFVMDGSQYHH-A--AEL
AqueK412_Aque DCWKQEADERPTFEYLHHTLNDYFVSAADTAY--R--MLT
:**. .. ***** *: *:: :