GCN2_Hsap MAGGRGAPGRG------------------------------------------------R
Gcn2_Dmel MADEKAK-----------------------------------------------------
GCN2_Mmus MAGGRGASGRG------------------------------------------------R
GCN2_Scer MSLSHLT-----------------------------------------------------
Y81G3A.3_Cele MTKENQIV---------------------------------------------------L
DDB0216407_Ddis MPPKPKQKAKQPSQQPPPPPPPAAAQLIEDILSSDEEEGGVKLPTKSSVKNALKKVKKER
IfkB_Ddis ------------------------------------------------------------
11434_Tthe MQLNNGSIA--------------------------------------------------F
18670_Tthe MNLQINI-----------------------------------------------------
21870_Tthe MNSKQTKGI--------------------------------------------------Q
GCN2_Spur MDEEIQR-----------------------------------------------------
CC1G_02807_Ccin MDSTE-------------------------------------------------------
AqueK195_Aque MEDQ--------------------------------------------------------
AqueK194_Aque MEDQ--------------------------------------------------------
AqueK193_Aque MLASS-------------------------------------------------------
PEKc_Smoe LQVYL-------------------------------------------------------
PEKa_Smoe LQVYL-------------------------------------------------------
GK065_Glam MDEET-------------------------------------------------------
GCN2_Hsap D-EP-PE----------------------------------------SYPQRQDHELQAL
Gcn2_Dmel ------E----------------------------------------SFRERQAQELEVI
GCN2_Mmus A-EP-QE----------------------------------------SYSQRQDHELQAL
GCN2_Scer -----LD----------------------------------------QYYEIQCNELEAI
Y81G3A.3_Cele D-ER-VK----------------------------------------ENQHLQEEEKLAL
DDB0216407_Ddis DREL-IR----------------------------------------QLKDQQDMELEAL
IfkB_Ddis ------------------------------------------------------------
11434_Tthe D-NQQLNSQTQ------------------------------------RVEENQGSLLSNL
18670_Tthe --------QIN------------------------------------TLWIDRQTILCFI
21870_Tthe D-QSS-QQQSQSSAPKLSKAQKRIKQKQEEFRARLEKNRPQPIDTLHQLNEALNVEIEKL
GCN2_Spur ------R------------------------------------------QE-AMKELKKK
CC1G_02807_Ccin --------------------------------------------------ELQQLEITAL
AqueK195_Aque -----------------------------------------------SYEERQRDELEFL
AqueK194_Aque -----------------------------------------------SYEERQRDELEFL
AqueK193_Aque ------------------------------------------------IS----------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam ------------------------------------------------WFRDVTDSIEVG
GCN2_Hsap EAIYGADFQ-------------DL-RPDA-----------CG--P-V--KEPPEINLVLY
Gcn2_Dmel KSIFGCDVE-------------DL-RPQA-----------NP--S-L--WKPTDIRIQLT
GCN2_Mmus EAIYGSDFQ-------------DL-RPDA-----------RG--R-V--REPPEINLVLY
GCN2_Scer RSIYMDDFT-------------DL-TKRK-----------SS----W--DKQPQIIFEIT
Y81G3A.3_Cele DAVYLNQIT-------------YI-KA-------------HW--H-V--WVPTNCHILLK
DDB0216407_Ddis QAIFNDEFI-------------TM-DPIIINRNMDTIIEGIK--P-I--RESARFRITIK
IfkB_Ddis ------------------------------------------------------------
11434_Tthe LSIIFSEQNLIALVIFLIGYFVGRRKRNK------------PLKN-D--EVQIQNE--E-
18670_Tthe GS-----YS----TILYIQDNRGSSKKQK------------QIAS-Q--DISAQQN--Q-
21870_Tthe RSIYMENMI-------------GL-PPEH---------------G-Y--YRSFQIN--LF
GCN2_Spur KDLTKQDSD-------------ES-RESR-----------ER--H-N--SDPPGS-QSPT
CC1G_02807_Ccin KSIFGNDFI-------------EC-PPPK-----------AW--KGA--ARLPEFIIQVT
AqueK195_Aque QFVFMSDFE-------------DM-REKD-----------TW--K-I--QRPPEIMIKLT
AqueK194_Aque QFVFMSDFE-------------DM-REKD-----------TW--K-I--QRPPEIMIKLT
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam RSLFQVNLP-------------PL-PKGS-----------SF--YQYSISFSPVFLIVEE
GCN2_Hsap PQG-----LT---G--------EE-VYVKVDLRVKCPPTYPD------V-V-PEIELK-N
Gcn2_Dmel PLR-----DSSNG---------LE-TYVCTKLHVTCPSKYPK------L-P-PKISLE-E
GCN2_Mmus PQG-----LA---G--------EE-VYVQVELRVKCPPTYPD------V-V-PEIDLK-N
GCN2_Scer LRS-----VD---K--------EP-VESSITLHFAMTPMYPY------T-A-PEIEFK-N
Y81G3A.3_Cele ALD--SCFLNGDPL--------GK-SKLSVILHVKCSEDYPQ------R-K-PAVDLL-D
DDB0216407_Ddis PYV--------GDD--------EK-CFVSIYLVVGFPEKYPV------V-L-PSIQVL-V
IfkB_Ddis ------------------------------------------------------------
11434_Tthe ---LQNKIFNSDSSQQGVTSTKQT-FNIE-----QNRSDFTGLNFDQNS-F-SQRGVI-E
18670_Tthe -----NKILQNDS---------------------QYALDYPN------F-P-KTQNKT-K
21870_Tthe PQQLKLKYQDENAS--------DQ-AEFYLFLIFNIPREYPD------Q-M-PKVSVK-S
GCN2_Spur RKR-----VDSGS---------L---------DSS-DSSSPK------T-K-GKWQFD-Q
CC1G_02807_Ccin N--------P---D--------YP-DKISVNLHVKLPKTYPH------L-ACPIFTLQKP
AqueK195_Aque PQK-----SISTSV--------QR-LQISVKLHAKYSSDYPD------T-P-PQLDLI-E
AqueK194_Aque PQK-----SISTSV--------QR-LQISVKLHAKYSSDYPD------T-P-PQLDLI-E
AqueK193_Aque -------------------------------------SS---------------------
PEKc_Smoe -------------------------------LRLACGKKGP-------------------
PEKa_Smoe -------------------------------LRLACGKKGP-------------------
GK065_Glam DD-------P---V--------LQQKAVDAQVHISITSKPSN------VLGEHDISF-RD
GCN2_Hsap AKGL-----------------------------------SNESVNLLKSRLEELAKK---
Gcn2_Dmel SKGM-----------------------------------SDQLLEALRNQLQAQSQE---
GCN2_Mmus AKGL-----------------------------------SNESVNLLKSHLEELAKK---
GCN2_Scer VQNV-----------------------------------MDSQLQMLKSEFKKIHNT---
Y81G3A.3_Cele PQGL-----------------------------------SKEDVQNLLTILRQMADT---
DDB0216407_Ddis NKGL-----------------------------------PQKKAIELEEKLIRESQG---
IfkB_Ddis ------------------------------------------------------------
11434_Tthe SRKYSNQSGGNYNEDISS-ANSDI--SFQNNENQ-------------VKN----------
18670_Tthe ----NKKKKSANGKEINQFNQSQAGLKNYSSEKHNIEYGSNEENILFKDSQSNIIQD---
21870_Tthe FKGF-----------------------------------AKQDEQLLQEKLFDYALK---
GCN2_Spur VEKG-----------------------------------GDTRIR---------------
CC1G_02807_Ccin AKGL-----------------------------------TNDQVSKLQQIINAEAQK---
AqueK195_Aque PHLL-----------------------------------SKDLVKELLTEINDLAKS---
AqueK194_Aque PHLL-----------------------------------SKDLVKELLTEINDLAKS---
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ---------------------------------------LPNSLSELTSQLSQLGVR---
PEKa_Smoe ---------------------------------------LPNSLSELTSQLSQLGVR---
GK065_Glam VVFL-----------------------------------GEARLKLLIQLVDNLKNDSLT
GCN2_Hsap -------------------HC-GEVMIFELAYHVQSFLSEH--NKPP---PK-SFHEEML
Gcn2_Dmel -------------------LR-GEVMIYELAQTVQAFLLEH--NKPP---KG-SFYDQML
GCN2_Mmus -------------------QC-GEVMIFELAHHVQSFLSEH--NKPP---PK-SFHEEML
GCN2_Scer -------------------SR-GQEIIFEITSFTQEKLDEF-QNVVN---TQ-SLEDDRL
Y81G3A.3_Cele -------------------WE-GCVVIAELAHRVREFLTDH--TPRP---AG-SFHDDML
DDB0216407_Ddis -------------------KI-GNIMIFDLCEIAKDFLNEN--NFEP---TQ-SIHHDFR
IfkB_Ddis ------------------------------------------------------------
11434_Tthe -------------------------------THKNSYLEDHFE----DNNLS-SQG----
18670_Tthe -------------------QS-TNPM-----NIKQSFSSLD-Y----KSPSL-EAL----
21870_Tthe -------------------NS-GKEMLFDLILQSRDYVESA-Y-KFHHKCIK-NIDL--K
GCN2_Spur ---------------------------------VRTF-----------------------
CC1G_02807_Ccin -------------------QR-GTEMVFTIANTCQDWLVNN--VTPV---SG-SLAVQMT
AqueK195_Aque -------------------RI-GEVMMLEIAQHVQSFLHKH--DR-P---PV-SLYEEMV
AqueK194_Aque -------------------RI-GEVMMLEIAQHVQSFLHKH--DR-P---PV-SLYEEMV
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe -------------------DVFRENL-------LYKFLFMQ--IMP-------SWAEDLV
PEKa_Smoe -------------------DVFRENL-------LYKFLFMQ--IMP-------SWAEDLV
GK065_Glam LTDFINGVFLLTQNRMCDDKS-DNLLVF--PSGAESFIAPN--RVEL---HSHSAYTSLR
GCN2_Hsap E-RRAQEEQ-QRLLEAKR-----KEEQEQREI-LHEIQ--RRKEEIKEEKKRKEM-----
Gcn2_Dmel Q-DKQKRDQ-EL-QDIQR-----QRESLQRQTLIDEVE--RRKEMFKTEAKRRGE-----
GCN2_Mmus E-RQAQEKQ-QRLLEARR-----KEEQEQREI-LHEIQ--RRKEEIKEEKKRKEM-----
GCN2_Scer Q-RIKETKE-Q-LEKEER-----EKQQETIKK-RSDEQ--RRIDEIVQR-----------
Y81G3A.3_Cele A-NKVRTEA-EK-QRKRL-----DTEQKELEL-LEEEM--RQRNAIEMEKTLNGT-----
DDB0216407_Ddis S-HQQKISI-EISTNEQQQQQLQQLQQLQLQY-NNDTK--KEWESTLEESQLKEDRKNYR
IfkB_Ddis ------------------------------------------------------------
11434_Tthe -------------KSAVKNES--QVS-------NEN-S--KQL--IQQSQQIKF------
18670_Tthe -------------EKL---------S-------KKS-L--KKL--GKEQKVK-P------
21870_Tthe T-YQMKNED-IKQLQLIERKE--KEE-------LEERQ--KKKKELEEKQALKM------
GCN2_Spur ------SGS-NT-S----------RQLI--ETSHHNSH--RKARLVKQLSGGK-------
CC1G_02807_Ccin Q-RALDEERNRKQREAEE-AA-REEERRKR-E-AEELEAQIEQDALRQLMAREQQ-----
AqueK195_Aque K-RREKEAE-EESKKKFQEQEV-ARHQRQEEI-AQELQ--RRQDQLREK-----------
AqueK194_Aque K-RREKEAE-EESKKKFQEQEV-ARHQRQEEI-AQELQ--RRQDQLREK-----------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe S-RQPQMFQ---------------------------------------------------
PEKa_Smoe S-RQPQMFQ---------------------------------------------------
GK065_Glam RSREVHALLQERLNQSDE--A-H--KNTQL-V-IN------------QVLAEH-------
GCN2_Hsap -----AK-Q-----ERLEIASLSNQDHTSKK-------DPGGHRTAAILHGGSPDFVGNG
Gcn2_Dmel -----PR-R----SM-SES----NPRHPSSS-------ESS-------------------
GCN2_Mmus -----AK-Q-----ERLEITSLTNQDYASKR-------DPAGHRAAAILHGGSPDFVGNG
GCN2_Scer ---ELEKRQD--DDDDLLFNRTTQLDLQPP----------------------S-EWVASG
Y81G3A.3_Cele -----RQ-E----NE-TRI----I----------------G-------------------
DDB0216407_Ddis LQKSIQRAQYEKERKKTIVNEFTNGPQ-SKL-------SKQ-----Q-RNIDY-------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe -------GSDNQSSENQ---YKHYQ----G-ELALVPFKQ------N-------------
18670_Tthe -------TEQSDESFNL-IIREIDV----L-KCIFEDQ----------------------
21870_Tthe -------LQQEKQREN--ILRMNENDEQKLRMQWLNERDK------I-------------
GCN2_Spur --------------------------------------KD--------------------
CC1G_02807_Ccin ----FKS-RERANSETTEVPFMSDTPLETF----------------------SQ-DIHLG
AqueK195_Aque ---LLQDFDEESSSDDELVTKNSNKQT-SQK-------DSD-----DITNPPL-------
AqueK194_Aque ---LLQDFDEESSSDDELVTKNSNKPT-GQK-------DSD-----DITNPPL-------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam ---------EYIHTETKLIQHRGMGKIPPT----------------------VQ-NIQN-
GCN2_Hsap KHRANSSGRSRR-----ER-QYSVCNSEDSP-------GSCEIL--YFN-MGSPDQLMVH
Gcn2_Dmel -----------------EN-SSPYYRGHIYPSKCLD-HRNTETL--YFH--K-M-GRQIQ
GCN2_Mmus KARTYSSGRSRR-----ER-QYSVCSGEPSP-------GSCDIL--HFS-VGSPDQLMVH
GCN2_Scer EAIVFSKTIKAKLPNNSMFKFKAVVNPKPIK-------LTSDIF--SFS-----------
Y81G3A.3_Cele -----------------GR-RIV-------------------------------------
DDB0216407_Ddis -----SI------------------------DHSINNNNNNNNNAFNNF-NN-N-NNN--
IfkB_Ddis ------------------------------------------------------------
11434_Tthe --------------------------------------GNSNY--YNNNIHNMQNQLMID
18670_Tthe ------------------------------------------------------------
21870_Tthe ----------------------------------------------IQNV----------
GCN2_Spur ---------------------------------------HVTVI--KFH-TK-G-DRNVH
CC1G_02807_Ccin DVR-----------------------------------FNTVKL--FYP-RQG-P-SPFG
AqueK195_Aque -----P-------------------------PPLEDN---------PIV-GR-G-NGNIL
AqueK194_Aque -----P-------------------------LPLEDS---------PIV-GR-G-NGNIL
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam ----------------------------------------SILP--I-Y-LQG-SKGTHQ
GCN2_Hsap KGKCIGSD-------------------------------------------EQLGKLVYN
Gcn2_Dmel RGCCVGHS-------------------------------------------QR-GCIAYT
GCN2_Mmus KGRCVGSD-------------------------------------------EQLGKVVYN
GCN2_Scer ---------------------------------------------------KQFLVKPYI
Y81G3A.3_Cele ------------------------------------------------------------
DDB0216407_Ddis ------------------------------------------------------------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe NGSCS--DNKSSSQAQQPLQRKLLNDIGSALVKKKARHNKMYGL---SEESEEELL----
18670_Tthe -------MKIIIPHSKKIMGQIQIDLFQSRIP------ENLRTI---IRFK---YT----
21870_Tthe -------QQEGRDHSNSIQSQNQSSNQS--------------NNSERQFNSKEKYILDYY
GCN2_Spur KGILLGSN-------------------------------------------PE-GSSVYA
CC1G_02807_Ccin FGHR-----------------------------------------------VHGADLLIA
AqueK195_Aque RGKLLGDS-------------------------------------------SHGYYSVYC
AqueK194_Aque RGKLLGDS-------------------------------------------SHGYYSVYC
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam RGRI-----------------------------------------------APGMRIVI-
GCN2_Hsap ALETA--TGGFVLLYEWVLQWQKKMGP-----FL------TSQEKE--------------
Gcn2_Dmel GIDMH--CGQLLYITEWNIKYSQLEQP-----CIGGGKCHWSSESKCM------------
GCN2_Mmus ALETA--TGSFVLLHEWVLQWQK-MGP-----CL------TSQEKE--------------
GCN2_Scer PPESP--LADFLMSSEMMENFYYLL-----------SEIELDNSYF--------------
Y81G3A.3_Cele VLSNM--PNTQLLISEWTFRFSSNRNP-------------AEGKRK--------------
DDB0216407_Ddis ----------------------------------------N-------------------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe FEQCTFKNPP------------LR------------KKADFKIEFEQDDAKGVYRKIETH
18670_Tthe YT---IEYPF------------T----------------------------PVHFVVEPK
21870_Tthe ENQCDVQDVLIMNLIDLVVKLLNL------------DQNSIKNL-TSALN----------
GCN2_Spur GMDAH--SGDLLTIREWVIKWKQGKGR-----K------PLPDEEE--------------
CC1G_02807_Ccin GL-------QTVYLAEPVVDDLHTTPPLELHIYT------FESSYY--------------
AqueK195_Aque GMEVD--SGSLVCIYEWIIPCKTQ------------KKADTRRSRQAGGAG---------
AqueK194_Aque GMEVD--TGSLVCVYEWIIPCKTQ------------KKADTRRSRQA-GAG---------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam -------------------DVV--KTNLELVKAL------VESSYV--------------
GCN2_Hsap -------KIDKC-----------------------KK-----------------------
Gcn2_Dmel -------GSHRV-----------------------DE-----------------------
GCN2_Mmus -------KIDKC-----------------------KR-----------------------
GCN2_Scer -------NTSNG-----------------------KK-----------------------
Y81G3A.3_Cele -------DFAPF-----------------------LQ-----------------------
DDB0216407_Ddis ----------NT----------------------NNS-----------------------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe QVITDYVQTKEIHK----------------------------------------------
18670_Tthe QNIPDRIDATKFRSQLIEDIKKVAKKQQEKMEESVFNICSMILDFVKEFDEEWIQQQQAK
21870_Tthe --------------------------NYPNL--FQDD-----------------------
GCN2_Spur -------DAEAC-----------------------LK-----------------------
CC1G_02807_Ccin -------STSQG-----------------------RK-----------------------
AqueK195_Aque -------SVGRS----------------------EGN-----------------------
AqueK194_Aque -------SVGRS----------------------EGN-----------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam -------NETRT------------------------------------------------
GCN2_Hsap -QIQ--GTETE---------------------------FNSLV--KL--SH----P----
Gcn2_Dmel -VMA--SIEKQ---------------------------VSSLS--QL--QH----K----
GCN2_Mmus -QIQ--GAETE---------------------------FSSLV--KL--SH----P----
GCN2_Scer -EIA--NLEKE---------------------------LETVL--KA--KH----D----
Y81G3A.3_Cele -KLD--AVYNE---------------------------IQKLC--EIKGLD----Q----
DDB0216407_Ddis -NVS--SIDNK---------------------------TIDKQ--QTMI------L----
IfkB_Ddis ------------------------------------------------------------
11434_Tthe -EIE--EIKQT---------------------------FSSQF--QI--KE----N----
18670_Tthe GQQQQLQMYKN---------------------------PSTIL--ED--QD----E----
21870_Tthe -MTK--VIRQQ---------------------------YNYVF--STITKNTLKAF----
GCN2_Spur -QCA--SVEQE---------------------------LLSLL--RL--EH----A----
CC1G_02807_Ccin -KLK--QVEQE---------------------------IKDLT--VT--RH----D----
AqueK195_Aque -LVA--SIRQE---------------------------YDSFS--ERFINH----S----
AqueK194_Aque -LVA--SIRQE---------------------------YDSFS--ERFISH----S----
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam -FVA--KSNQTDIAGYTGSRISLPASGGGLKLGEEVPLADSFFEPIF--SH----QEKIQ
GCN2_Hsap ----------N--V--VRYLAM---NLKEQ----DDSIVVDILVEH--------------
Gcn2_Dmel ----------N--L--VSYECV---LCIK---R-KEGLLVYLVQDF--------------
GCN2_Mmus ----------N--I--VRYFAM---NSREE----EDSIVIDILAEH--------------
GCN2_Scer ----------N--V--NRLFGYTVERMGRN-NA-TFVWKIRLLTEY--------------
Y81G3A.3_Cele ----------N--L--VEYAFV---HLQKISVS-PDQILIQLNVAQ--------------
DDB0216407_Ddis ----------H--L--LRLL-----------------------CQ---------------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe ----------Q--N--VNG-----------------------------------------
18670_Tthe ----------NADT--VHT-----------------------------------------
21870_Tthe ----------HKQA--VKN---------IS----NYSQTVQDLIHC--------------
GCN2_Spur ----------N--I--VHYLAM---NYNK---G-KEDINVQLLMEY--------------
CC1G_02807_Ccin ----------H--L--LATLAV---KLKLPH-S-SDPAQLIVLTEQ--------------
AqueK195_Aque ----------S--I--VKYLLM---RHNLT----EHGILVEVTMEY--------------
AqueK194_Aque ----------S--I--VKYLLM---RHNLT----EHGILVEVGMEY--------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam AQGTAMFTLAS--LISIYFL-V---MLSLQR-NIRGGIATNRFYDFLALVTQEECDIRPW
GCN2_Hsap ------------ISGVSLAAHLSHSG---PIPVHQLRRYTAQLLSGLDYLHSNSVVHKVL
Gcn2_Dmel ------------LLGTSVFSI-SSSL---GWCMDGARMVARGVLDALVFLHNKGVSHSHL
GCN2_Mmus ------------VSGISLATHLSHSG---PVPAHQLRKYTAQLLAGLDYLHSNSVVHKVL
GCN2_Scer ------------CNYYPLGDLIQSVG---FVNLATARIWMIRLLEGLEAIHKLGIVHKCI
Y81G3A.3_Cele ------------KIFSS-EENMQDTYELIVQKSNLLRLLAAQAICGLRYLHEASMTHKHL
DDB0216407_Ddis -------------------------NDS-NITNDHIKTLGEQLVQ-------MGI-FNRN
IfkB_Ddis ------------------------------------------------------------
11434_Tthe ------------------------------------------------------------
18670_Tthe ------------------------------------------------------------
21870_Tthe ------------ISGN-----------------------QDRQESLLNRVQQNLVLTKQQ
GCN2_Spur ------------VGGGNLSQKLENSS---LTSFDLLREYAIDLLSGLQYLHSHAVVHKQL
CC1G_02807_Ccin ------------TPHVTLHDVLVDCH---SLREDRATQYLTQILQALNALHNKNLVHRGM
AqueK195_Aque ------------ITGGSLNSLLQGSSSS-PITGKSLQLYSKQLLEAVAYLHSQGIVHNDI
AqueK194_Aque ------------ITGGSLNSLLQGSSSS-PITGKSLQLYSKQLLEAVAYLHSQGIVHNDI
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam LHVYKALRLLPLQPDGAVSAWLSSTA---SVPV-TLRDLREEILQHIEHIYGLGVTNTS-
GCN2_Hsap SASN---VLVD---AEG---TVK----ITD-----YSISKR-----LADICKEDV--F--
Gcn2_Dmel LDTT---VFMD---NTG---NVR----VSD-----FSLVPN-----LLELLSGAG-----
GCN2_Mmus SASS---VLVD---AEG---TVK----ITD-----YSISKR-----LADICKEDV--F--
GCN2_Scer NLET---VILVKDA-DFGSTIPKLVHSTYG-----YTVLNM-----LSRYPNKNGSSV--
Y81G3A.3_Cele TLGS---VWTR---NSTGDCVFR----FSD-----FGSMGP-----LLDLVKMFG-----
DDB0216407_Ddis HLSL---LNMH---NSN---DNQ----IYQHIFQDY-FLKQFNDISLSDLKNNVD-----
IfkB_Ddis ------------------------------------------------------------
11434_Tthe -------------------------------------FKMS-----LVKQNLQ-------
18670_Tthe -------------------------------------LPQN-----VKQSDMS-------
21870_Tthe -SSYS-Q----CS--CQG---QK----INN-----SQIKKS-----QSKNNISSN--Y--
GCN2_Spur RASQ---VYVD---CDG---RLR----VAN-----YSMCKR-----LNELAQAAN-----
CC1G_02807_Ccin DVRCLGLVSSRTNPGQK---VIK----VGK-----AVFHTH-----LLDLHRSNS--FGP
AqueK195_Aque RPSL---VFID---PVQ---GVK----LAG-----HTIIKR-----LSDLTGKVN-----
AqueK194_Aque RPSL---VFID---PVQ---GVK----LAG-----HTIIKR-----LSDLTGKVN-----
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------ATFKRI-FKQTVD-------KDNVS-----
PEKa_Smoe ------------------------------ATFKRI-FKQTVD-------KDNVS-----
GK065_Glam ---SEF------------------------------------------------------
GCN2_Hsap ------------EQT-RVRFSDNA-LPYKTGKKGDVWRLGLLLLSLSQGQ---ECGEY--
Gcn2_Dmel ----------------------------QSSSCGDLPALGALVESLMPT-----------
GCN2_Mmus ------------EQA-RVRFSDSA-LPYKTGKKGDVWRLGLLLLSLSQGQ---ECGEY--
GCN2_Scer ---------ELSPSTWIAPEL-LKFNNAKPQRLTDIWQLGVLFIQIISGS---DIVMNFE
Y81G3A.3_Cele ---------DICSGKYVARDEDKEK--EYDRRRKDLFQLGTLLDGLILAT---RGSTYSR
DDB0216407_Ddis ------------SAA---------------------------------------------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe ---------------------V------IPMLEKM--------KSQSISEINNLNDSA--
18670_Tthe ---------------------C------I---DNS--------MSKNKSSLDQLQSYA--
21870_Tthe -------------EIVMNGFSE------INNIKNN--------LSASSGSAGGNQTSS--
GCN2_Spur ------------EGKQTVRFSDDKTYGGRGGKKGDVLDLGLLLLGLLLGT---SDVQY--
CC1G_02807_Ccin HIPPVADEPQISDGWLSREMKDSA-L--LYTKRRDIHNVGIILLQMLMGL---DVTER--
AqueK195_Aque ------------EEAWPRGF-----FTKLGGKKTDILKLGMVIFCMSVGR---VTVSY--
AqueK194_Aque ------------EEAWPRGF-----FTKLGGKKTDILKLGMVIFCMSVGR---VTVSY--
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------E-----------------------------------------------
PEKa_Smoe ------------E-----------------------------------------------
GK065_Glam -----------------------I-R--LVQQRPETIEQQM-------------------
GCN2_Hsap -P-VTIP--SDLP---------ADFQDFL--KKCVCLDDKE-------------------
Gcn2_Dmel ----------N-S---------YEMRDFV--DKCNS---DR-------------------
GCN2_Mmus -P-VTIP--SDLP---------ADFQDFL--KKCVCLDDKE-------------------
GCN2_Scer TP-QEFLDSTSMD---------ETLYDLL--SKMLNNDPKK-------------------
Y81G3A.3_Cele VP-TPVEGNQNTG----T----NLLGNFI--AKCQE------------------------
DDB0216407_Ddis ----NNS--GHFL---------NKFWDTL--NKTNENS----------------------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe -QRGQFN--S------------YEKE------QQ--------------------------
18670_Tthe -IK-KSF--V------------YEYQ-----DKL--------------------------
21870_Tthe -P-KDSN--Q------------QEMQ-----KKK--------------------------
GCN2_Spur -P-CEVP--QDLP---------LDLQDFL--NRCIDIDERS-------------------
CC1G_02807_Ccin -Y-SDVQ--EAIHSSAISPVLARQATNMLTP--TKKNNISC-------------------
AqueK195_Aque -P-PDVP--EHFS---------EDFKDFL--NKCLNNNEYQ-------------------
AqueK194_Aque -P-PDVP--EHFS---------EDFKDFL--NKCLNNNEYQ-------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam ------------------IIEHYQNTDCLSFAKTSSDNVTVGIRQPSTIEAQLGLESRMM
GCN2_Hsap ---RWSPQQLLKHSFINPQ------PKMPLV-EQSPEDSEGQ-D-----YV---------
Gcn2_Dmel ---TLSASELLEHPFLRFYVDNGQQQVMPLPQQQHPNTV--Q-R-------TGS------
GCN2_Mmus ---RWSPQQLLKHSFINPQ------PKLPLV-EQSPEDSGGQ-D-----YI---------
GCN2_Scer ---RLGTLELLPMKFLRTNIDSTIN-RFNLV-SESVNSNSLELTPGDTITVRGNGGRTLS
Y81G3A.3_Cele ---AKNIDQLVEDPFLKEE-------------------C--Q-S-------ESE------
DDB0216407_Ddis ---GLKK--------------------SPSTFEYSG--EGGG-G-----GV---------
IfkB_Ddis ------------------------------------------------------------
11434_Tthe ------LALYMKSPFEVET------RISPL-YE---Q-----------------------
18670_Tthe ------LGDFR-----EEV------NLSRQSLSSTDQDQ----------Q----------
21870_Tthe --------LRLNNSDNGEK------RLSD-SADSLQSDH----------QI---------
GCN2_Spur ---RANVQSLLDHPFIKPTISDNP--DPPS-VSSSESRA--Q-E-------ESS------
CC1G_02807_Ccin ---MTLLSELAEDS-LK-----------ASL-QQTPMTSRSI-P-----IMNSSGGP---
AqueK195_Aque ---RYPAHELLVHPFITPP------TFIPGSIDHTHRTEAGF-G-----PLRDK------
AqueK194_Aque ---RYPAHELLVHPFITPP------TFIPGSIDHTHRTEAGV-G-----LLRDK------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ---FWNA--------------------SPDL---LG------------------------
PEKa_Smoe ---FWNA--------------------SPDL---LG------------------------
GK065_Glam AALQSF-YVLLKD----------------------PFD-------------ERTGLI---
GCN2_Hsap ETVIP--SN--RLP---SAAFFSETQRQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGC
Gcn2_Dmel -----------AMP--Y---QIPTLALSQSRLRTEFEVLMYLGKGAFGDVLKVRNILDNR
GCN2_Mmus ETVIP--SN--QLP---SAAFFSETQKQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGC
GCN2_Scer QSSIRRRSF--NVG---S-RFSSINPATRSRYASDFEEIAVLGQGAFGQVVKARNALDSR
Y81G3A.3_Cele -------------N---IFTPFGGAMSPDGRMLADNVIIRVLGRGGFGDVVLVRNKMDST
DDB0216407_Ddis -----------GGG---S-SQKTINPHQQSRYHSDFEEIQLLGRGGFGQVVKVRNKLDGR
IfkB_Ddis ----------------------------------------MIGKGGFGVVVKSRNKLDCR
11434_Tthe --------------------SHIKQYLDNGKFNKFFRVIDELGRGGFGRVYKVQSMVEEK
18670_Tthe --------------------EEKVLENLKSAYKTNFEEVEQIGKGGFGQVYKVKNRLDSL
21870_Tthe QTQ----DK--KNN---L-LSFEPANTEKSRYLTDFEEIQVLGQGAFGQVVKVRNKLDGR
GCN2_Spur -----------ALD--FPGVPTADINLGVSRLHSEFEFLAFLGKGGFGNVIKVRNKLDGN
CC1G_02807_Ccin RTPVP--SMYYGSPEVDYVMHRMRQARQSSRWKDDWEELELLGKGAFGSVVKARNKVDNR
AqueK195_Aque -------SA--DSS---L-ADPVSHAGGRSRLEAEFEVLEVLGKGGFGDVIKVRNYLDSR
AqueK194_Aque -------SA--DSG---L-ADPVSHVGGRSRLEAEFEVLEVLGKGGFGDVIKVRNYLDSR
AqueK193_Aque ------------------ASSSYSAHSESSRFTRDFEEIKLLGKGAFGEVYHVKHNLDKK
PEKc_Smoe -------------------ENDGNLAAMNSRYLSDFEELCLLGKGGFGHVVLCKNKLDGR
PEKa_Smoe -------------------ENDGNLAAMNSRYLSDFEELCLLGKGGFGHVVLCKNKLDGR
GK065_Glam ----------------DPFSINGYLKATKSVYLKDFVELYQLGKGGYGEVVCANRLMENQ
:*:*.:* * . ::
GCN2_Hsap CYAVKRIPINPAS------------RQFRRIKGEVTLLSRLHHENIVRYYNAWIERHERP
Gcn2_Dmel EYAIKRIPLPARSR-----------QLYKKMTREVELLSRLNHENVVRYFNSWIESVDDA
GCN2_Mmus CYAVKRIPINPAS------------RHFRRIKGEVTLLSRLHHENIVRYYNAWIERHERP
GCN2_Scer YYAIKKIRHTE--------------EKLSTILSEVMLLASLNHQYVVRYYAAWLEEDSMD
Y81G3A.3_Cele DYAIKRIPLNAKSD-----------KLNRKIAKEAKFFAKLNHPNMVRYYYAWAEDLIPI
DDB0216407_Ddis YYAIKKIKLDSN------------QSLNRRILREVITLSRLHHQHVVRYYQAWIESAESL
IfkB_Ddis YYAIKKIKTKGYTDS-------NQEPLTNKLLREVTTLSRLHHQFVVRYYQAWIEKSCDS
11434_Tthe IYAIKKIAVPYDG---------FSNPKEHKYFREVKSIMSLNHINIVRYHTSWWENCDDE
18670_Tthe NYAVKKIKLDIN-----------QKELTKKTLKEVKLLSILQHNHIVRYYQAWLEKPDEK
21870_Tthe YYAIKKIKIRKG-------------QNIEKLMREVTLLSRLHHRHVLRYYQAWLEESNQS
GCN2_Spur LYAIKKILLNPKSR-----------ELNKKITREVKLLSRLNHENVVRYYNSWIEVAEEP
CC1G_02807_Ccin VYAVKKVRLKAVQ-------------KDDKIMREVNALSRLNHRFIVRYYTTWIETTEAP
AqueK195_Aque LYAIKKVRLTGG------------SKMMTKLTREVELLSQMNHENIVRYYNAWIEKYSEP
AqueK194_Aque LYAIKKVRLTGG------------SKMMTKLTREVELLSQMNHENIVRYYNAWIEKYSEP
AqueK193_Aque EYAMKIIPANK---------------INQKDLREVLALSDFKHSGIVQYYCSFIDDCAKV
PEKc_Smoe RYAMKKVKLKDE-------------NPSDKILREVATLSRLQHQHVVRYYQAWFETAAGG
PEKa_Smoe RYAMKKVKLKDE-------------NPSDKILREVATLSRLQHQHVVRYYQAWFETAAGG
GK065_Glam KYAVKKVVIDRRDFHAKTESVGGFLQYIKSIMNEVRILSRLLHPFIVKYYYSWIETTSDT
**:* : *. : : * :::*. :: :
GCN2_Hsap AGPGTPPP--D----------SGPLAKDD-------------------------------
Gcn2_Dmel DAAEMDKL--L-GGE---------------------------------------------
GCN2_Mmus AVPGTPPP--D----------CTPQAQDS-------------------------------
GCN2_Scer ENVFESTD--E----------ESDL-----------------------------------
Y81G3A.3_Cele VEETSDDD--S-SLGAVPIPGKEKIGKKG-------------------------------
DDB0216407_Ddis SLTNDNSDDDDD-----------D---DD-------------------------------
IfkB_Ddis FQSLEEGNEDLSGDL------ETD---ASEDWFMQSSINSRSIISRDSYSGLSTSNSNVG
11434_Tthe MVNQVNEF--L-QT-------NNNL-----------------------------------
18670_Tthe TLQEFENS----EE-------EDEL-----------------------------------
21870_Tthe EEEES-----M----------GSQM-----------------------------------
GCN2_Spur PTTDTDES--R-TTG---------------------------------------------
CC1G_02807_Ccin STTVSDDS--S-A-E------SSMI-----------------------------------
AqueK195_Aque NHHGNEEE----GEE------FSD------------------------------------
AqueK194_Aque NHHGNEEE----GEE------FSD------------------------------------
AqueK193_Aque AAGWTSY-----H-S------RS-------------------------------------
PEKc_Smoe SSGTPYG-----------------------------------------------------
PEKa_Smoe SSGTPYG-----------------------------------------------------
GK065_Glam VQNATEA-----P-N------SSMI-----------------------------------
GCN2_Hsap ----RAARGQPASD----------------------TDGLD-----------------SV
Gcn2_Dmel -------WSQSQQD----------------------LSVKP---------------AK--
GCN2_Mmus ----PATCGKTSGD----------------------TEELG-----------------SV
GCN2_Scer ------------------------------------------------------------
Y81G3A.3_Cele ----KLKTGKSLEDKE----------------N---KANLGGGDSLMPMNLRGLVKDHSI
DDB0216407_Ddis ----EFESGSESEESQ----------------SESESESSE-----------------SE
IfkB_Ddis GANNTAGGGDSVSNANSNKSMIVGNNNKKLTLSSSNTSSSS-----------------SL
11434_Tthe ------------------------------------------------------------
18670_Tthe ------------------------------------------------------------
21870_Tthe ------------------------------------------------------------
GCN2_Spur -------TGETSPD----------------------TNGVGRGAREVPLAVNSLSLSDNI
CC1G_02807_Ccin ------------------------------------------------------------
AqueK195_Aque ------------------------------------------------------------
AqueK194_Aque ------------------------------------------------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam ------------------------------------------------------------
GCN2_Hsap EAAAPPPIL------SSSVEWSTS------------------------------------
Gcn2_Dmel ------------------------------------------------------------
GCN2_Mmus EAAAPPPIL------SSSVEWSTS------------------------------------
GCN2_Scer ---------------SE-------------------------------------------
Y81G3A.3_Cele G--------------VDAKEWSTP-------------------------FGKPEGPKCAS
DDB0216407_Ddis ES-------------SES------------------------------------------
IfkB_Ddis LSNNKSKILNTSKSTSTN-----TSTSTSTSNTNKNKKISKKKKSKLSPLMKPKNKKNKN
11434_Tthe -Y-------------SDD------------------------------------------
18670_Tthe -R-------------EDS------------------------------------------
21870_Tthe -S-------------DQD------------------------------------------
GCN2_Spur EEQALKLSI------RNSLEWSS-------------------------------------
CC1G_02807_Ccin ---------------TSS-EVTSI------------------------------------
AqueK195_Aque -S-------------SED------------------------------------------
AqueK194_Aque -S-------------SED------------------------------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam ---------------SSG-CTTGT------------------------------------
GCN2_Hsap ----GERSA-SARFPATGPGSSDDE--DDDEDE--HGGV-FSQ-SFLPA-SDSESD-I--
Gcn2_Dmel -------------SPQLGPTLEEDE--D-EED---SSSS-MWN-GYIPNMEDSDSDGI--
GCN2_Mmus ----AERST-STRFPVTGQDSSSDE--E-DEDE--RDGV-FSQ-SFLPA-SDSDSD-I--
GCN2_Scer -------------------SSSDFE--ENDLLD--QSS-IFKN-RTNHDLDNSNWD-F--
Y81G3A.3_Cele RMRQSKRSTPSGGLKHLSECSSDDE--D-DDD---SSEI-DWD-AESEEVEDEESDDSDE
DDB0216407_Ddis -----EES------------SESSE---SEES-----------------EESEYSDDS--
IfkB_Ddis N----GES------------EQSSS---DSENG--ENGM---KSRIIENASDSYSDDD-N
11434_Tthe ------NS------------PSVSEAYQKNKSDYNRSYA-LS-K---QTNQTQ-SYVL-S
18670_Tthe ------KE------------EECSSENDSAPSKASKESS-MC-FEFIESSEES-SLPF-E
21870_Tthe -----DDN------------GELSDD------RYRYRSN-----NFSS-----------R
GCN2_Spur -------------SGNIGLIGDSDD--S-SSD---DEGV-FGR-SFLPRSDDSSSDGI--
CC1G_02807_Ccin ----PDDDS-ERHLPINGGFDLGDL--DD-LDD--ELGS---Q-SS-------FPS-I--
AqueK195_Aque -----EDT------------TEEEE--EEEEER--EEGLSFIEFKLDESTTLNSSDQI-R
AqueK194_Aque -----EDT------------TEEEE---EEEER--EEGLSFIEFKLDESTRLDSSDQI-R
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe -----EES------------EISSS---WVDT-----------------P----------
PEKa_Smoe -----EES------------EISSS---WVDT-----------------A----------
GK065_Glam ----GDDSL-E---------------------G--SLG---------------AV-----
GCN2_Hsap ----------------------IF-DNEDENS--K-------------------------
Gcn2_Dmel ----------------------EF-VDSNG-K--V-------------------------
GCN2_Mmus ----------------------IF-DNEDENS--K-------------------------
GCN2_Scer ISG-------------SGYPDIVF-ENSSRDD----------------------------
Y81G3A.3_Cele EDEDDGERLVQLNTETSTGADSVF-ERSTADE--D----------------------VV-
DDB0216407_Ddis EFE-------------SEENND------FDQS--FSEVFLFQNGNKR-SLEF----DLTD
IfkB_Ddis NNN-------------NDSNNNYHSDN-ESDS--FSGSISMSDGNGS-GYEATDDEDIIN
11434_Tthe YNN-------------DNLSCIEW-EQSE------N------------------------
18670_Tthe FEN-------------YSDNGIVF-EDSDGDEEQKQ------------------------
21870_Tthe YQD-------------NN--SSYY--D--LS--SL-------------------------
GCN2_Spur ----------------------DF-EGSDRGE--E-------------------------
CC1G_02807_Ccin ----------------------HF-EGSKSPA--N-------------------------
AqueK195_Aque DDS-------------YSFSSDVFTDTEDRDV--FKGKVDTPGTNVATLLEA--DLMVTT
AqueK194_Aque DDS-------------YSFSSDVFTDTEDRDV--FKGKVDTPGTNVATLLEA--DLMVTT
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam ------------------------------TR--A-------------------------
GCN2_Hsap -----------------------------------------------------------S
Gcn2_Dmel ------------------------------------------------------------
GCN2_Mmus -----------------------------------------------------------S
GCN2_Scer ---------------------------------------------ENEDLDHDTSSTSSS
Y81G3A.3_Cele ----F----------------------------------T----AES------------E
DDB0216407_Ddis DSYSFLHSDCGFLLEVFDLNNKIGGNNTRSMGSSNQHLQQQQQQNQSQQQKKQPQQNQ-S
IfkB_Ddis NSGSFD---------------------------------D----NEND-------DDD-E
11434_Tthe ---------------------------------------------ENQN----------P
18670_Tthe ---------------------------------------------KNQN----------S
21870_Tthe ------------------------------------------------------------
GCN2_Spur -----------------------------------------------------------S
CC1G_02807_Ccin -----------------------------------------------------------S
AqueK195_Aque PRRGFIHS----------------------------------------------------
AqueK194_Aque PRRGFIHS----------------------------------------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------------------------------------------------------------
PEKa_Smoe ------------------------------------------------------------
GK065_Glam -----------------------------------------------------------L
GCN2_Hsap --QNQ--------D----------------ED----CNEK--------------NGCHE-
Gcn2_Dmel ----------AVYD----D-----------EE---QED----------------STR---
GCN2_Mmus --QNQ--------D----------------ED----CNQK--------------DGSHE-
GCN2_Scer --ESQD-------DT--DK-----------ES---KSIQN--------------VPRRRN
Y81G3A.3_Cele --DLNA----KRRES--IE-----------LM---EINTT--------------TTSKSK
DDB0216407_Ddis --QQQK----KLKNS--NSKSKSKSKSK-SKSKS-KSNSK--------------KSISSS
IfkB_Ddis --EDDD----DEYDE--EDDDY-ETFDFQDKSRVVSNNSK--------------LSTSSS
11434_Tthe NISNNDGIKKKLDDS--QT-----------IN---EYREQ--------------NKSHKT
18670_Tthe STANNKQETHKRKESQIQD-----------ID-ETDFFTK--------------EDKKKH
21870_Tthe ------------RNS--QD-----------S----SVREQ--------------SGKNQE
GCN2_Spur --DISL----SISNR--VK-----------ES---KGNRG--------------KSKEED
CC1G_02807_Ccin --DSSG-------D----------------DS---LFDSM--------------SPTNKN
AqueK195_Aque -------------------ESS-DSVVFQDTSLMAPPGGEGEEGSTAAAGGGGGAGGGRA
AqueK194_Aque -------------------ESS-DSVVFQDTSLMAPPGGEGEEGSTATG---GGGAGGRA
AqueK193_Aque ------------------------------DT---TFSS---------------------
PEKc_Smoe ---------------------------------------------------------GSS
PEKa_Smoe ---------------------------------------------------------GSS
GK065_Glam --DSPS------------------------ST---PFSTP--------------K---PT
GCN2_Hsap -SEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQ-------------GL-------YRDT--
Gcn2_Dmel -GKTNSPKPLMQVMYIQMEFCEKCTLRTAIDD-------------NL-------FNDT--
GCN2_Mmus -IEPSVTAEAVHYLYIQMEYCEKSTLRDTIDQ-------------GL-------FRDT--
GCN2_Scer FVKPMTAVKKKSTLFIQMEYCENRTLYDLIHS-------------ENL------NQQR--
Y81G3A.3_Cele LAIDVVPVRKPRILCIQMEYCDRATLRQYIDE-------------NHC------FNAP--
DDB0216407_Ddis KLKNIKKSTSIPYLYIQMEYCQK-ILRNLTET-------------GM-------NLED--
IfkB_Ddis ---RKKPPKETHTLYIQMEYCSKKTLKTLIDN-------------VG-------GIAE--
11434_Tthe -FNFTKEPSQLLTLYIQLEYCSGKTLRNYLDE-------------QTH------GLDS--
18670_Tthe --HKKKKSKDFRLLHIQMEFCGGSTLREMIDN-------------HFFCAEKEKRISS--
21870_Tthe NQKYPVTNFKLMILFIQLEYCPS-TLSHQIKE-------------LKF------QQDT--
GCN2_Spur ISEDNPVFSPVQYLYIQMEFCEKSTLRTAIDA-------------GM-------YEDK--
CC1G_02807_Ccin -LTFPSNFGPSRTLYIQMEFVERQTLRERVDE-------------GI---------SE--
AqueK195_Aque ---KQKQTGQSQYLYIQMEYCSNQTLKVLIDS-------------GQ-------LVKSPG
AqueK194_Aque ---KQKQTGQSQYLYIQMEYCSNQTLKVLIDS-------------GQ-------LIKSSG
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ---SNDVNTVSTFLYIQMEYCPR-TLREVFDT-------------RS-------VLDK--
PEKa_Smoe ---SNDVNTVSTFLYIQMEYCPR-TLREVFDT-------------RS-------VLDK--
GK065_Glam -RSTERREIEKVIVFVQMEYCSHGCLSGFIQQCSDGAALCPPLAQGL--------TLT--
GCN2_Hsap -VRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDD-----HVKIGDFGLATDHLAF
Gcn2_Dmel -DRLWRLFREIAEGLAHIHQQGIIHRDLKPVNIFLDSHD-----QIKIGDFGLATTSFLA
GCN2_Mmus -SRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDD-----HVKIGDFGLATDHLAF
GCN2_Scer -DEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESR-----NVKIGDFGLAKNVHRS
Y81G3A.3_Cele -TEVWRIFSEVLCGLKYMHDMAMIHRDIKPLNIFLTSQN-----GVKIGDFGLATLEAMS
DDB0216407_Ddis -DDIWKLFRQIVEGMAYVHGQGIIHRDLKPSNIFFDSCG-----DIKIGDFGLAINNKTT
IfkB_Ddis -EEAFRLLRQIVEGLNHIHSQQIIHRDLKPANIFIDNEQ-----NVKIGDFGLATSGAPV
11434_Tthe -KEAFQIFSQMLEGVNYLHKNQIIHRDLKPSNILFEN-K-----IAKIADFGLSIQQELG
18670_Tthe -KQKKSLLAQILEALKYLHEKELIHRDLKPQNILLDQSG-----QIKLVDFGLATTLKKE
21870_Tthe -VQIWQYFRQILEGLNYIHSQNTIHRDLKPENIFIDCLG-----DIKIGDFGLAKSQKQN
GCN2_Spur -RRLWTHFREIIEGLAHIHLQGMIHRDLKPVNIFLDSND-----FVKIGDFGLATSEQMA
CC1G_02807_Ccin -EEGWRLFHQIVDALVHMANLGIIHRDIKLTNIFIALAKIMGLTLFPVGDFGLATSSLAA
AqueK195_Aque FELGWQLFREITEGLAHIHSQGMIHRDLKPVNIFLNSSG-----HCKIGDFGLATTFSKY
AqueK194_Aque FELGWQLFREITEGLAHIHSQGMIHRDLKPVNIFLNSSG-----HCKIGDFGLATTFSKY
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe -ELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRN-----DVKIGDFGLGVCAAKF
PEKa_Smoe -ELTWGIFRQIVEGLSHIHGQGIIHRDLTPSNIFFDTRN-----DVKIGDFGLGVCAAKF
GK065_Glam -ELLWRMTAQLASAVAYIHSKDIVHYDIKPANVFLDESY-----NIKLGDFGTSYTCKGP
GCN2_Hsap SADS---KQD-----D--------------------------------------------
Gcn2_Dmel L--Q---AHD-----A--------------------------------------------
GCN2_Mmus TAEG---KQD-----D--------------------------------------------
GCN2_Scer LDIL---KLD-----S--------------------------------------------
Y81G3A.3_Cele SKGK---IVG-----GAAEKS---T-----------------------------------
DDB0216407_Ddis STLSPTTNIN-----SSTSSAGSLTTSSNSVQSVINTKQQQQQQQPQNYWEDEVEGQQQQ
IfkB_Ddis SKS---DDLN-----SSTSNAANNINL-------SS------------------------
11434_Tthe LI-N---AN---------------------------------------------------
18670_Tthe RQIE---RKAVLNLKRASSVQ-SNF-----------------------------------
21870_Tthe VF-S---KYQ-YVIEKEEN-----------------------------------------
GCN2_Spur GALT---SEV-----SCHNR----------------------------------------
CC1G_02807_Ccin VDPS-----D-----V--------------------------------------------
AqueK195_Aque HTGL---SRQ--------------------------------------------------
AqueK194_Aque HTGL---SRQ--------------------------------------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ADLQ---NPD-----QD-------------------------------------------
PEKa_Smoe ADLQ---NPD-----QD-------------------------------------------
GK065_Glam SDDQ-----D-----L--------------------------------------------
GCN2_Hsap ------QT--------G-DLIKSDPSGHLTGMVGTALYVSPEVQGS--------------
Gcn2_Dmel ------AP-------APVNQITSAEDGTGTGKVGTTLYVAPELTGNA-------------
GCN2_Mmus ------QA--------GDGVIKSDPSGHLTGMVGTALYVSPEVQGS--------------
GCN2_Scer ------QN-------LP------GSSDNLTSAIGTAMYVATEVLDG--------------
Y81G3A.3_Cele -SI-EAML-------SPNGVKSKGSDVHQTRDIGTQLYMAPELFVDE------------L
DDB0216407_Ddis QQQ-QQQQ-------QQQQQQQQQQQQQHTARVGTLFYTSPEQEAGT-------------
IfkB_Ddis STN-STAQ-------QTPMWDLNDENLSMTGGVGTPFYCCPEILEKN-------------
11434_Tthe ----QELP-------SQKNIDGQDISVAHTGNVGTPFYMPPEQQDK--------------
18670_Tthe -YNASSLPGEIDYKDKKSENSNNYFPSEITRGVGTGVYRAPEQEN---------------
21870_Tthe -----ELFNQLV--NKQYLTEKELEAIDQTLNVGTYFYRPPAS-----------------
GCN2_Spur ------LT-------DSSHSGEATPGNHLTGKVGTALYVAPELCKA--------------
CC1G_02807_Ccin ------QH--------K--PVTY--DPEMTLEVGTRLYIAPEVQWTG------------R
AqueK195_Aque ------QS-------IPSN--TS-ILAGDTGLVGTMLYLAPELLKS--------------
AqueK194_Aque ------QS-------IPSN--TS-ILAGDTGLVGTMLYLAPELLKS--------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ------HR-------VPVKFEANVKSLEGTGQVGTYFYRAPEIEQA--------------
PEKa_Smoe ------HR-------VPVKFEANVKSLEGTGQVGTYFYRAPEIEQA--------------
GK065_Glam ----------------------------FASDRSTLSYMAPELSAQHWMQSSLNNAAQSN
GCN2_Hsap -TKSAYNQKVDLFSLG--------------------IIFFEMSYHPMVTASERIFVLNQL
Gcn2_Dmel -SKSVYNQKVDMYTLG--------------------IILFEMCQPPFDTSMERAQTIMAL
GCN2_Mmus -TKSAYNQKVDLFSLG--------------------IIFFEMSYHPMVTASERIFVLNQL
GCN2_Scer --TGHYNEKIDMYSLG--------------------IIFFEMIYP-FSTGMERVNILKKL
Y81G3A.3_Cele VHKAPYTSKIDIYSAG--------------------VVLFEMFYRPLPPSMDRVSTLNNL
DDB0216407_Ddis NGDSAYDDKVDMYSLG--------------------IVFFEMWYV-FSTGHERVIVLRNL
IfkB_Ddis --TKHYGTKVDMYSLG--------------------IIFFEMCFQ-FQTQMERSNILRDL
11434_Tthe --SGKYNEKIDVYSLG--------------------IILLEIIHK-MDTYHEKLEIVKKL
18670_Tthe --TSSYCTKADMFSLGILNQAKQYFNNLIFKINKIGVIIFEMWYP-LPTFMEKYQTLKEI
21870_Tthe --QSMHEERADIYALG--------------------IIFFEMWFY-FQSKYQRFKVLTIL
GCN2_Spur -RIGHYNQKVDLYSLG--------------------IIFFEMCYRSLSTGMERVKILGQI
CC1G_02807_Ccin RAAPKNHNKADMYSLG--------------------IVFFEMNYR-FTTGSERIVVLEDL
AqueK195_Aque --VVKYTQKVDMYSLG--------------------IILYEMSHPPPATVMERVKILTDV
AqueK194_Aque --VVKYTQKVDMYSLG--------------------IILYEMSHPPPATVMERVKILTDV
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe --WPHIDEKVDMYSLG--------------------VILFELWHP-FSTGMERYVTLNEL
PEKa_Smoe --WPHIDEKVDMYSLG--------------------VILFELWHP-FSTGMERYVTLNEL
GK065_Glam LPVTALRKQADMYSLG--------------------ITLLELWFL--PTASDNLSNLRVL
GCN2_Hsap RDPTSPKFPEDFD-DGEHA----KQKSVISWLLNHDPAKRPTATELLKSE--LLPPPQME
Gcn2_Dmel RNVS-INIPDAMLKDPKYE----KTVKMLQWLLNHDPAQRPTAEELLISD--LVPPAQLE
GCN2_Mmus RDPTSPKFPDDFD-DGEHT----KQKSVISWLLNHDPAKRPTAMELLKSE--LLPPPQME
GCN2_Scer RSVS-IEFPPDFD-DNKMK----VEKKIIRLLIDHDPNKRPGARTLLNSG--WLPV-KHQ
Y81G3A.3_Cele RDD--IKIPSDFG-AGLAAPMAGLARRTVEKMLQRNPDERPTADDLLNDE--DLPMHTKE
DDB0216407_Ddis REKF--EFPSDFE-RN-HS----RQATLIRMLIDKDPAKRPSAQQLLQSE--LMPP-KME
IfkB_Ddis RDNL--KFPPGFE-ST-KP----DQTQIIRSLLSRDPTQRPSTKQLLESG--LLPS-KME
11434_Tthe KGSQ--ELPKNLQ-KT-QKYA----CELIIQMTSLKPQNRPSIEQILQG---------K-
18670_Tthe REKN--QLPQDFN-LK-VGNDAKEIRDILTKLLDPDPSKRYSAEELLKT---------LE
21870_Tthe RNNN--LFPDQFE-QF-HPKQ----AKLIAWMLNFSSQKCQKVMEIMQSD--LIPP-KIE
GCN2_Spur RQES-IQLPEDFD-EVRNT----NENAIVHWLLNHDPKERPTSQELLESK--LLPPPQME
CC1G_02807_Ccin RKPG-IFFPTSWE-PH-RT----RQREIITWLLQHDPEKRPSALDLSQSP--LMPP-RVE
AqueK195_Aque RKKE-IVFSERFK-TS-KK----MSKQ---------------------------------
AqueK194_Aque RKKE-IVFSERFK-TS-KK----MSKQ---------------------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe KQQN--ILPSNWA-AK-FP----HQAALVHLLVSPHPQDRPSAREVLQSE--LLPP-RME
PEKa_Smoe KQQN--ILPSNWA-AK-FP----HQAALVHLLVSPHPQDRPSARDVLQSE--LLPP-RME
GK065_Glam VQNK--QLPSEFT-ET-HP----NVSAILYQLCDVHPLKRLTASALIEALSALNLP-VI-
GCN2_Hsap ESELH---------------EVLHHTL----TNV-DGKAYRTMMAQIFSQR---------
Gcn2_Dmel ANELQ---------------EMLRHAL----ANP-QSKAYKNLVARCLQQE---------
GCN2_Mmus ESELH---------------EVLHHTL----ANI-DGKAYRTMMSQIFCQH---------
GCN2_Scer DEVIK---------------EAL-KSL----SNP-SSPWQQQVRESLFNQS---------
Y81G3A.3_Cele DATFR---------------NLCEKVI----KKR-DGRMNAWLLDKQFKEE---------
DDB0216407_Ddis DEYIK---------------NSI-RVI----TNP-TNQFYQTMLNSLFSQN---------
IfkB_Ddis DDILK---------------EAI-KTI----ANP-TISLFSYLMEKLFCLS---------
11434_Tthe ------------------------------------------------------------
18670_Tthe DEQYL---------------EHL-SQI----TNP-NNADHRKLIEYLFKVQ---------
21870_Tthe DDYIV---------------DAI-KAL----NNP-SGPVFKQILEALFKGG---------
GCN2_Spur DARLQ---------------DMLHQTV----ANR-QSKGYHYLMTELFAVE---------
CC1G_02807_Ccin DEYFH---------------QALG-LM----AKP-DTPHYQTVLSLLFNQP---------
AqueK195_Aque ---------------------AVEHTL----QNP-NSSQYKRLMEKLFSQE---------
AqueK194_Aque ---------------------AVEHTL----QNP-NSSQYKRLMEKLFSQE---------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe DEALK---------------DIL-RTI----HSTDNTFVFDQVIAALFDEE---------
PEKa_Smoe DKALK---------------DIL-RTI----HSADNTFVFDQVIAALFDEE---------
GK065_Glam SAVFKNVPYVVTCSPENRLSDILN-LLEHSEDGI-SQEDRHALMNFLIKDSYCAGLSLLS
GCN2_Hsap ISPAIDY----TY------------------------------------DS---DILKGN
Gcn2_Dmel SDEVLEH----TY------------------------------------HL---GSSRAM
GCN2_Mmus ISPAIDY----TY------------------------------------DS---DILKGN
GCN2_Scer YSLTNDI----LF------------------------------------DN---SVP---
Y81G3A.3_Cele VPTSLNY----CY------------------------------------DV---DICLE-
DDB0216407_Ddis HQHLHSH----IY------------------------------------HHQQSSVTSS-
IfkB_Ddis NDEHIMS----RY------------------------------------LYTS-------
11434_Tthe ------------------------------------------------------------
18670_Tthe NLPSAIY----TV---------------------------------------EPYIKLIR
21870_Tthe HKVNEIS----NI--------------------------------------QHFTSHTGQ
GCN2_Spur SRPVADF----TY------------------------------------DI---DMHKG-
CC1G_02807_Ccin TKASRGF----LY------------------------------------DK---DLDR--
AqueK195_Aque NSKLFEM----SF------------------------------------FSEHSSLDLD-
AqueK194_Aque NSKLFEM----SF------------------------------------FSEHSSLDLD-
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe KLA--SK-----T------------------------------------DNEA-NLSIG-
PEKa_Smoe KLA--SK-----T------------------------------------DNEA-NLSIG-
GK065_Glam LRESRDALAELPSPTSLTRPQDYCKPETKSICKQGVLSAKRRCDVLEVPNK---SAQE--
GCN2_Hsap ----------FSIRTAKMQ-QHVCETIIRIFKRHGAVQLCTPL-LLPRNRQIY-------
Gcn2_Dmel KSWNSAIIIDDIVSLNPVI-EFVKAKVVNLFRKHGAIEVDSPL-LSPLSARNST------
GCN2_Mmus ----------FLIRTAKIQ-QLVCETIVRVFKRHGAVQLCTPL-LLPRNRQIY-------
GCN2_Scer --------TS-TPFANILR-SQMTEEVVKIFRKHGGIENNAPPRIFPKAP-IY-------
Y81G3A.3_Cele --------RAKYNNREVLV-ETLRAEFCKILKIHSFEKLHTHT-LMPVSTALAA------
DDB0216407_Ddis -SYSKSLF-C-SLDLLQVK-QLVDDVIITILKKHNANEMLTPQ-MSIIKEWNEQPNLFNN
IfkB_Ddis ---N-PSL---TPMHLICR-EKTFSRLEKIFLNHGSIRIDTPT-LFPKNPTNST------
11434_Tthe ------------------------------------------------------------
18670_Tthe -------F-------TQSY-QLIQDRIKSVFEAHGGINLEANP-LVPLTENIYL------
21870_Tthe -------LE------SQFN-NYFISKIYSFFEHKGVLNYESPL-NVPPPTVQLK------
GCN2_Spur ----------FSLKNSLTQ-QMVYDTVQRIFQKHGAVRINTIM-LLPKTKLYE-------
CC1G_02807_Ccin ------------PEYLSLA-DAVQDRLAALFKLHGAVDIEPPL-LMPVVDRE--------
AqueK195_Aque -KVNKSSF---SPTYFLLQ-QFVWNVTESVFNKHCGLCVNVPF-LEPMTESLV-------
AqueK194_Aque -KVNKSSF---SPTYFLLQ-QFVWNVTESVFNKHCxxxxxxxx-xxxxxxxxx-------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe ---DLDHL---TPKWLTAQ-ELVIGLTKDVLTRHGARKFRSPS-MTVASDVKT-------
PEKa_Smoe ---DLDHL---TPKWLTAQ-ELVIGLTKDVFTRHGARKFRSPS-MTVASDVKT-------
GK065_Glam ------------PFDVCLETSWIEGFIEHVLLLMGTVPITLPS-TVPYASLRP-------
GCN2_Hsap -----------------------------------------------------------E
Gcn2_Dmel ------------------------------------A---------------------NA
GCN2_Mmus -----------------------------------------------------------E
GCN2_Scer -----------------------------------------------------------G
Y81G3A.3_Cele ------------------------------------A---------------------SV
DDB0216407_Ddis SSSSSSTTTTTSTTNTANNTNSVVINKSTSTSNINKV---------------------SN
IfkB_Ddis ------------------------------------H---------------------PG
11434_Tthe ------------------------------------------------------------
18670_Tthe ------------------------------------NKLYLNTKQSRLQFRVKMYHNIIK
21870_Tthe ------------------------------------DDVNIEI-------------EKNK
GCN2_Spur -----------------------------------------------------------H
CC1G_02807_Ccin -----------------------------------------------------------D
AqueK195_Aque -----------------------------------------------------------G
AqueK194_Aque -----------------------------------------------------------x
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe -----------------------------------------------------------S
PEKa_Smoe -----------------------------------------------------------S
GK065_Glam -----------------------------------------------------------D
GCN2_Hsap HNEAALFMDHSGMLVMLPFDLRIPFARYVARN----------------------------
Gcn2_Dmel NANAVHLMTHSGCVVVLPCDLRTQFARHVTMN----------------------------
GCN2_Mmus HNEAALFMDHSGMLVMLPFDLRVPFARYVARN----------------------------
GCN2_Scer TQNVYEVLDKGGTVLQLQYDLTYPMARYLSKN----------------------------
Y81G3A.3_Cele RTKPVEVLDRSGVPVALPMDLRQNFVRFCVRN----------------------------
DDB0216407_Ddis KTGKSILMDDSGQLLELRHDLRVSFKSFIETEF------------LNLGDHYKHHHQQQN
IfkB_Ddis AANVAKFLDESGTVVYLPYDLTIPWARHVVIH----------------------------
11434_Tthe ------------------------------------------------------------
18670_Tthe RQYKSIMLANTGTLVEFSDNLLTPWIQKVKTRHYIQMKKLEKRDNL--------------
21870_Tthe FSNNPTLMTKDGNIIYLRQTLRESFKKHLRKVNKIF------------------------
GCN2_Spur SDMCAHFMDHSGGIVTLPYDLRVPFARYIARN----------------------------
CC1G_02807_Ccin EKNHATFIDRMGTLVSLPNNLLVPFARLAAKG----------------------------
AqueK195_Aque MEGTVQLLESTGKIITLPQHHWLSFSRYVLQH----------------------------
AqueK194_Aque xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx----------------------------
AqueK193_Aque ------------------------------------------------------------
PEKc_Smoe NRSAVKVINSSGTMFELRYDTRLLFARWVVLN----------------------------
PEKa_Smoe NRSAVKVINSSGTMFELRYDTRLLFARWVVLN----------------------------
GK065_Glam AQQYASV---SDCNVFLTARLTQQLL----------------------------------
GCN2_Hsap -----------------------------------------NILNLKRYCIERV-FRPRK
Gcn2_Dmel -----------------------------------------SVNLIRRYCVDRV-YREER
GCN2_Mmus -----------------------------------------NILNLKRYCIERV-FRPRK
GCN2_Scer -----------------------------------------PSLISKQYRMQHV-YRPPD
Y81G3A.3_Cele -----------------------------------------SVQRMKRFNFGRV-YSQTS
DDB0216407_Ddis DVRHDNSSNGNSNNNNSNDRHHDQDKSNTTTRSVDEILELLSKAPIKRYEFGHV-FRKPH
IfkB_Ddis -----------------------------------------NIQQAKRYTFSKV-YRRSQ
11434_Tthe ------------------------------------------------------------
18670_Tthe -------------------------------------LQKELSSMIKRYTFACIQFQDSE
21870_Tthe ----------------------------------------LSNQVFKRYELGQA-FRYQQ
GCN2_Spur ---------<