B0414.7_Cele    WALLDHIASGSFGSVHRAMDIDSHRVIAAKVMRIQRENHKAIE---SEINIFRQLIHENL
Mekk1_Dmel      WHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHKNL
MAP3K4_Mmus     WQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNL
MAP3K4_Hsap     WQRGNKIGEGQYGKVYTCISVDTGELMAMKEIRFQPNDHKTIKETADELKIFEGIKHPNL
MEKK4_Spur      WQRGFKIGEGQFGTVYSCINMNTGETLAVKEMRFQRNDHQVIRDIADEIKNLEGIRHPNL
AqueK228_Aque   WRRGRKLGEGQFGVVYECINLDRGEVQAVKMISLKEKSHNTVRDILSEVGVFQSINHKNI
                *    ::..* :* *: .:. :  .  * * : ::  . ..:.   .*:  :. : * *:

B0414.7_Cele    VKYYGVQVEDSDVIIFMEYCSQGTLERICHG--KMDLKMVRQYTNSLLRAVQYLHSHKII
Mekk1_Dmel      VRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIV
MAP3K4_Mmus     VRYFGVELHREEMYIFMEYCDEGTLEEVSRL--GLQEHVIRLYTKQITVAINVLHEHGIV
MAP3K4_Hsap     VRYFGVELHREEMYIFMEYCDEGTLEEVSRL--GLQEHVIRLYSKQITIAINVLHEHGIV
MEKK4_Spur      VRYYGVEIHRFKMYHFLQYLTRTTLKFVCHL--GLQEHEISLIIKNMN----DLN-----
AqueK228_Aque   VHFHGVEIHDTDLYLFMEYCNQGTLWGAAKQ--GLEERMIRLYTRDLLRAVDVLHDRGIV
                *::.*:::.  .:  *::   . **    .    :          .:      *:

B0414.7_Cele    HRDIKPANIFLDK-CTVLKLGDFGCSSRLVE-SSTVYGEFQTTAGTPQFMAPEIYSYGEK
Mekk1_Dmel      HRDIKTANIFLVDGSNSLKLGDFGSAVKIQA-HTTVPGELQGYVGTQAYMAPEVFTKTNS
MAP3K4_Mmus     HRDIKGANIFLTS-SGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKG
MAP3K4_Hsap     HRDIKGANIFLTS-SGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKG
MEKK4_Spur      --------------------------------QHFMPYKIYSKMLSAAYMAPEVINQTGK
AqueK228_Aque   HRDIKGANIFLSD--DSVKLGDFGLSVQLHNVNKTAPQEIKHQRGTIPYMSPEVVLM---
                                                      :.     :  :*:**:

B0414.7_Cele    DETTGSYSGYGRSVDIWALGATVVNMMTGKVPFEG-QTR-HQIAFALCFRKQKPTYP-DI
Mekk1_Dmel      -------DGHGRAADIWSVGCVVVEMASGKRPWAQFDSN-FQIMFKVG-MGEKPQAP-ES
MAP3K4_Mmus     -------EGHGRAADIWSLGCVVIEMVTGKRPWHEYEHN-FQIMYKVG-MGHKPPIP-ER
MAP3K4_Hsap     -------EGHGRAADIWSLGCVVIEMVTGKRPWHEYEHN-FQIMYKVG-MGHKPPIP-ER
MEKK4_Spur      -------DGYGRQADIWSLGCVVIEMVTGKRPWHDYDHE-FTIMYKVG-EGAVPHIP-DA
AqueK228_Aque   -------QDMGRPMDIWAVGCVVVEMFTSKRPWIELEDNAMAIMFQLG-NKKSPSYPAEK
                       .. **  ***::*..*::* :.* *:   : .   * : :      *  * :

B0414.7_Cele    ADKRPDVKRFFDNCFEFLPNDRPTAAELLQTTFA
Mekk1_Dmel      --LSQEGHDFIDHCLQHDPKRRLTAVELLEHNFC
MAP3K4_Mmus     --LSPEGKAFLSHCLESDPKIRWTASQLLDHAFV
MAP3K4_Hsap     --LSPEGKDFLSHCLESDPKMRWTASQLLDHSFV
MEKK4_Spur      --MNPEGKEFLSNCLKHDCTKRWTANKLLDHPFL
AqueK228_Aque   --MNDEMIDFLDLCFETDPKQRAVASKLLSHSFV
                     :   *:. *::   . * .* :**.  *