Protein (view, download) , Domain (view, download)
MSK2_Hsap       MGD---------------------------------------------------------
MSK1_Hsap       MEE---------------------------------------------------------
MSK2_Mmus       MGD---------------------------------------------------------
MSK1_Mmus       MEG---------------------------------------------------------
C54G4.1_Cele    ME----------------------------------------------------------
JIL1_Dmel       MSRLQKQNYEILSGTSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKN
MSK_Spur        ------------------------------------------------------------
AqueK023_Aque   ------------------------------------------------------------


MSK2_Hsap       ----------------EDDDE---------------------------------------
MSK1_Hsap       ----------------EGGSSGGA-AGT--------------------------------
MSK2_Mmus       ----------------EDEDE---------------------------------------
MSK1_Mmus       ----------------EGGGSGGA--GT--------------------------------
C54G4.1_Cele    ------------------------------------------------------------
JIL1_Dmel       SNSETMTNGKKSKLNTEGSGSGSGKTLNYNNNNNNNNSISATNGQYTNSSSKTTSASARD
MSK_Spur        ------------------------------------------------------------
AqueK023_Aque   ------------------------------------------------------------


MSK2_Hsap       --------------------------------------------------SCAVELRITE
MSK1_Hsap       ------------------------------SA----------DGGDGGEQLLTVKHELRT
MSK2_Mmus       --------------------------------------------------GCAVELQITE
MSK1_Mmus       ------------------------------SG----------DSGDGGEQLLTVKHELRT
C54G4.1_Cele    --------------------------------------------D---------------
JIL1_Dmel       YTYRETISPPTPPSPPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDEPNGIEIDESS
MSK_Spur        ------------------------------------------------------------
AqueK023_Aque   ------------------------------------------------------------


MSK2_Hsap       ANL---------------------------------------------------------
MSK1_Hsap       ANL---------------------------------------------------------
MSK2_Mmus       ANL---------------------------------------------------------
MSK1_Mmus       ANL---------------------------------------------------------
C54G4.1_Cele    -IL---------------------------------------------------------
JIL1_Dmel       SSLSKAKSNNAAAAAAAAAAAAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEA
MSK_Spur        ------------------------------------------------------------
AqueK023_Aque   ------------------------------------------------------------


MSK2_Hsap       ---------TGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAAL
MSK1_Hsap       ---------TGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATI
MSK2_Mmus       ---------TGHEEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAAL
MSK1_Mmus       ---------TGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATI
C54G4.1_Cele    ---------MPEGEKVSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRV
JIL1_Dmel       VTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITV
MSK_Spur        ------------------------------AYGKVFLVRKVGNHNQGKLYAMKVLKKATI
AqueK023_Aque   -----------HRVAIGPEDFELLTVLGTGGYGKVFLVRKVTGADQKQLYAMKVLKKTSV
                                              .**:******    :   :******.*  :

MSK2_Hsap       VQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQY
MSK1_Hsap       VQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER
MSK2_Mmus       VQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQY
MSK1_Mmus       VQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER
C54G4.1_Cele    LTKQKTLEHTMAERQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGH
JIL1_Dmel       VQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSEN
MSK_Spur        VQKAKTAEHTMTERQVLEAVRSCPFLVTLHYAFQTDSKLNLILDYVNGGELFTHLYQREH
AqueK023_Aque   VRKKKVMEHTLTERSVLEAIRDFPFLVTLHYAFQTETKLHLVMDYLCGGELFTHLHQIGP
                : : *. *** :** *** ::  ****.*.****:.:** :::::  ***:****

MSK2_Hsap       FKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKE
MSK1_Hsap       FTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETE
MSK2_Mmus       FKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKE
MSK1_Mmus       FTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETE
C54G4.1_Cele    FDLEAARFVIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGELD
JIL1_Dmel       FEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEY
MSK_Spur        FRESEVRIYIAEIIIALDCLH---------------------------------------
AqueK023_Aque   FSESGSRLYGAEITLALEHLHSLNILYRDIKLENILLDRDGHIVLTDFGLSKTMKPDQ--
                *     :.  .*: :*:: **

MSK2_Hsap       RTFSFCGTIEYMAPEIIRS-KTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVS
MSK1_Hsap       RAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEIS
MSK2_Mmus       RTFSFCGTIEYMAPEIIRS-KAGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVS
MSK1_Mmus       RAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEIS
C54G4.1_Cele    RANSYCGTIEYMSPEVINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIA
JIL1_Dmel       RAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEIS
MSK_Spur        ------------------------------------------------------------
AqueK023_Aque   VAHSYCGTVEYMAPEIIRGGDDGHNLLVDWWSLGVLLHELLTCESPFAPTGEDNSQKEIS


MSK2_Hsap       RRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAA
MSK1_Hsap       RRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAA
MSK2_Mmus       RRILKCSPPFPLRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVKSHPFFQGLDWVALAA
MSK1_Mmus       RRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKWDDLAA
C54G4.1_Cele    KRIMTKKVPFPKTMDVDARDFIGQLLEKKLEKRLGYN--GVDEIKNHKFMSSIDWDAAVK
JIL1_Dmel       RRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRT
MSK_Spur        -RILTSHPPMPNTFSKEVKDFINKLLVKDPTKRLGCN--GVKDIKSHSFFKGLNWDDVAA
AqueK023_Aque   RRILYEAPPIPHKLSPSCRELLFGLMRKNKDERLGAN--GAHEVKSHRWFSSLNWDDVLA
                 **       *  :.   ::::  :: *.  .*** .  .. :::.* ::. :.*

MSK2_Hsap       RKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQ-GYSFVAPSILFDH
MSK1_Hsap       KKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQ-SSEKLFQ-GYSFVAPSILFKR
MSK2_Mmus       RKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPAGSPPPGDPRIFQ-GYSFVAPSILFDH
MSK1_Mmus       KKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQ-SSERLFQ-GYSFVAPSILFKR
C54G4.1_Cele    RTLKPVIVPRIGHDLDTQFFSAEFTSQPPLYSPAESPL-NANTLFR-GYSYVSPSVIFAN
JIL1_Dmel       KRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPP-SRIRLFR-GYTYVAPEHLEQM
MSK_Spur        KRVSPPFRPHINGELDTSNFAEEFTSLVPADSPADIPKTADARVFRVGYSFIAPSILYSD
AqueK023_Aque   KKVRPPFKPYVSNEMDVGNFADEFTNQDPVDSPALPIS-KHNQVFR-GYSFIGPPVLFTS
                :   .   * :  : *.  *: ***   *  .           :*: **:::.*  :

MSK2_Hsap       NNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYELDLREPA-LGQGSFSVCRRCR
MSK1_Hsap       NAAV-IDPLQFHMGVERPGVTNVARSAMMKDSPFYQHYDLDLKDKP-LGEGSFSICRKCV
MSK2_Mmus       NNAVMADVLQAPGAGYRPGRAAVARSAMMQDSPFFQQYELDLREPA-LGQGSFSVCRRCR
MSK1_Mmus       NAAV-IDPLQFHMGVDRPGVTNVARSAMMKDSPFYQHYDLDLKDKP-LGEGSFSICRKCV
C54G4.1_Cele    DNVI-GEELMAE-----------DVNALLASSSFFAKYKLDKSDAGLLGKGAFSVVRRCE
JIL1_Dmel       RRDN-HCEIQYF-------------NTGLQNIPC-RPDDLELGT-R-TSNGAYGTCHFVV
MSK_Spur        NAI-TQDMLTQPSEHNRPSLASILSIHELKDSPFNKYYELDMKSAP-IGDGSFSICRRCT
AqueK023_Aque   NTVL-SS----------------LPPLLLHDSPFLQKYELS--NTN-LGTGSFSTCRVCI
                                            : . .     .*.       . *::.  :

MSK2_Hsap       QRQSGQEFAVKILSRRLEANTQREVAALRLC----QSHPNVVNLHEVHHDQ---------
MSK1_Hsap       HKKSNQAFAVKIISKRMEANTQKEITALKLC----EGHPNIVKLHEVFHDQ---------
MSK2_Mmus       QRQSGQEFAVKILSRRLEENTQREVAALRLC----QSHPNVVNLHEVLHDQ---------
MSK1_Mmus       HKKTNQAFAVKIISKRMEANTQKEITALKLC----EGHPNIVKLHEVFHDQVAASAQPPG
C54G4.1_Cele    RVVDGAQFAVKIVSQKFASQAQREARILEMV----QGHPNIVQLHDVHSDP---------
JIL1_Dmel       DSSTDLVFLAKIIPLSK--FRPSEVDALISCALDTTNHKNIVSYHGTFREK---------
MSK_Spur        HRKTEKEYAVKIVSRRVA--CTQEITTLQLC----QKHPNIVHLKEEFKDK---------
AqueK023_Aque   EKETKQEFAVKIVSKRH--NPMREISILQLC----QGHPNIVRLHEVLQDQ---------
                       : .**:.         *   *         * *:*  :    :

MSK2_Hsap       --------------------------------------------------------LHTY
MSK1_Hsap       --------------------------------------------------------LHTF
MSK2_Mmus       --------------------------------------------------------LHTY
MSK1_Mmus       QVVLCSLLLLALLFNRSLTRKPVTWTWLVHSTSQLPPLPPPMPEIVLFILLSDNGQLHTF
C54G4.1_Cele    --------------------------------------------------------LHFY
JIL1_Dmel       --------------------------------------------------------CETW
MSK_Spur        --------------------------------------------------------LHTY
AqueK023_Aque   --------------------------------------------------------LHVY
                                                                         . :

MSK2_Hsap       LVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYAD
MSK1_Hsap       LVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHD-VGVVHRDLKPENLLFTD
MSK2_Mmus       LVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYAD
MSK1_Mmus       LVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHD-VGVVHRDLKPENLLFTD
C54G4.1_Cele    LVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHD-KRIVHRDLKPENILFES
JIL1_Dmel       IVMEYLSGPELTASIRM----DEDSCREIFLQLVMAVRHIHS-KHFIHGDLKPENIMFEN
MSK_Spur        IIMELCKGGELLGRIRKKKHFDELEASMIMRKLVSAVDYMHS-RGIVHRDLKPENILFTD
AqueK023_Aque   IIMERLRGGELLDRIRSNNSFTEAQASHLFRQLVSAVHFIHS-KRVVHRDLKPENLIFSN
                :::*   * **   *:      * ..  :: .** ** .:*.   .:* ******::: .

MSK2_Hsap       DTP-GAPVKIIDFGFARLRPQSPGVP---------------------MQTPCFTLQYAAP
MSK1_Hsap       END-NLEIKIIDFGFARLKPPD-NQP---------------------LKTPCFTLHYAAP
MSK2_Mmus       DTP-GAPVKIIDFGFARLRPQSPAEP---------------------MQTPCFTLQYAAP
MSK1_Mmus       END-NLEIKVIDFGFARLKPPD-NQP---------------------LKTPCFTLHYAAP
C54G4.1_Cele    IDS-SARLRLVDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAP
JIL1_Dmel       RE-D-RTVKLIDFGSACYNNRFK-SW---------------------KDKPRYTLDYAPP
MSK_Spur        DSD-DAELKIIDFGFARITN-SN-QP---------------------LKTPCFSLHFAAP
AqueK023_Aque   EDDDTAVLKIIDFGFARLLPEAP-QV---------------------LTTPCYTLPYGAP
                       ::::*** *                                 .* ::* :..*

MSK2_Hsap       ELLAQ-----QGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQA--AEIMCKIREG
MSK1_Hsap       ELLNQ-----NGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSA--VEIMKKIKKG
MSK2_Mmus       ELLAQ-----QGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQA--AEIMCKIREG
MSK1_Mmus       ELLTH-----NGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSA--VEIMKKIKKG
C54G4.1_Cele    EVLDVG-DSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQ---ESA--TEIMQRICRA
JIL1_Dmel       EMLADA-N-LVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRG
MSK_Spur        EVLKRAYEQDGEYDASCDVWSLGVILYTMLSGRVPFQDPSISKS-NSA--SDIMKRIKHG
AqueK023_Aque   EVISH----SNGYTESCDIWSLGVILYTLLSGQAPFHAPTW-----PT--EKIVDCIQHG
                *::         *    *::.**. *: :* *: *::          :   .:   : ..

MSK2_Hsap       RFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVL
MSK1_Hsap       DFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDIL
MSK2_Mmus       RFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRSSSWLQDGSARSSPPLRTPDVL
MSK1_Mmus       DFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDIL
C54G4.1_Cele    EFSFTGDAWTNVSADAKNLITGLLTVDPKKRLSMQELTAHMWLKSSAS-MDTPLQTPSIL
JIL1_Dmel       TFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILDSEWLQYGSNDPDVDIILPQQM
MSK_Spur        NFSFDGEEWNSVSTPAKDLIKGLLTVDPSRRLTTDDLLQNEWIQGQQLSTSTPLMTPDIL
AqueK023_Aque   SVSFDSDEWSSVSSTAKSLIKGLLTVNTSQRLTIDSLSVHPWLMPDSA-PDTPLCTTVSL
                 ..  .  * ..*   : *:   *  :.  * . . :    *:       .  :  .  :

MSK2_Hsap       ESS-----------GPAVRSGLNATFMAFNR-GKREGFFLKS------------------
MSK1_Hsap       GSS-----------GAAVHTCVKATFHAFNK-YKREGFCLQN------------------
MSK2_Mmus       ESS-----------GPAVRSGLNATFMAFNR-GKREGFFLKS------------------
MSK1_Mmus       GSS-----------GAAVHTCVKATFHAFNK-YKREGFCLQN------------------
C54G4.1_Cele    PSS-----------A-D--ETFNETLRAFLH-ANRDGFHLLD------------------
JIL1_Dmel       VVDLSEDTMEQPTGG-MFDDQQQLEFMHDK-SAEDEGITLVSEPMDTTVATHESRRNAAA
MSK_Spur        NSC-----------A-SIQKRVKATMRAFHT-AQREGFLLTD------------------
AqueK023_Aque   KSL-----------G-ATRTAINHTLHAYYQVTSKDGLVLGD------------------
                              .       :  :       . :*: * .

MSK2_Hsap       --------------------------------VENAPL--AK------------------
MSK1_Hsap       --------------------------------VDKAPL--AK------------------
MSK2_Mmus       --------------------------------VENAPL--AK------------------
MSK1_Mmus       --------------------------------VDKAPL--AK------------------
C54G4.1_Cele    --------------------------------VAAAPL--MK------------------
JIL1_Dmel       FSSVVAPTTDDEIVHERFDPAFEVQADFYGFDENAPPLPLPEEYYSELPLPEEDRQYIPP
MSK_Spur        --------------------------------VSNAPL--AK------------------
AqueK023_Aque   --------------------------------PAQNPL--AR------------------
                                                    **   .

MSK2_Hsap       -------------RR---KQKLRSATASRRGSP----APANPG-----------------
MSK1_Hsap       -------------RR---KMKKTSTSTETRSSS----SESSHS-----------------
MSK2_Mmus       -------------RR---KQKLRSAAASRRGSP----VPASSG-----------------
MSK1_Mmus       -------------RR---KMKRTSTSTETRSSS----SESSRS-----------------
C54G4.1_Cele    -------------RR---GIKRQSGDKDASGNS----KNSRVT-----------------
JIL1_Dmel       PPALIPVEPETTFRRPRTRQQRRTESQLVQPVSVATYEDSKASLRVLMQQLPPPGDNVVA
MSK_Spur        -------------RR---KKKKDSST-ETRSSS----SESTHS-----------------
AqueK023_Aque   -------------KR---KLKSERSPQ---------------------------------
                             :*     :

MSK2_Hsap       ------------------------------------------------------------
MSK1_Hsap       ------------------------------------------------------------
MSK2_Mmus       ------------------------------------------------------------
MSK1_Mmus       ------------------------------------------------------------
C54G4.1_Cele    ------------------------------------------------------------
JIL1_Dmel       RIPKRTHRVVRTLPPTFGTTKREENFYGFSKTAISWRKTRASWRHFCLLINGVQQVLKVR
MSK_Spur        ------------------------------------------------------------
AqueK023_Aque   ------------------------------------------------------------


MSK2_Hsap       ----------------------------RAPV-ASKGAPRRANGPL--------------
MSK1_Hsap       ----------------------------SSSHSHGKTTPTKTLQPS--------------
MSK2_Mmus       ----------------------------RLPASAAKGTTRRANGPL--------------
MSK1_Mmus       ----------------------------SSSQSHGKTTPTKTLQPS--------------
C54G4.1_Cele    -----QFECLPEEQEAEMTSSTSRPSNLGMMN------------YR--------------
JIL1_Dmel       FKKARRVYCLPHIKEEKLDHAYEKPLTFPRPKAQLKRTKREPKVPR--------------
MSK_Spur        ----------------------------QSSSSQESTTPTPTANPVLTIPVTTVSCAPRT
AqueK023_Aque   --------------------PGTRPTT---------------------------------


MSK2_Hsap       ------------------------------------------------------------
MSK1_Hsap       --------NPA-------------------------------------------------
MSK2_Mmus       ------------------------------------------------------------
MSK1_Mmus       --------NPT-------------------------------------------------
C54G4.1_Cele    --------EPN-------------------------------------------------
JIL1_Dmel       --------PPT-------------------------------------------------
MSK_Spur        TTATGAPSIPSVQPLPSLSKQTGARLDQYESLESLGFSPILPFSAGGSQELPPLLARQDS
AqueK023_Aque   ------------------------------------------------------------


MSK2_Hsap       ------------------------------------------------------------
MSK1_Hsap       ------------------------------------------------------------
MSK2_Mmus       ------------------------------------------------------------
MSK1_Mmus       ------------------------------------------------------------
C54G4.1_Cele    ------------------------------------------------------------
JIL1_Dmel       ------------------------------------------------------------
MSK_Spur        GYVGQMPSYAQVTPVPRTNVGSHGVTYAPILDPSMYPCGLQQPILDFSSSIPEYLSVQYA
AqueK023_Aque   ------------------------------------------------------------


MSK2_Hsap       ----------------------------------------PPS
MSK1_Hsap       -------DSNNPETL------------------F--QFSDSVA
MSK2_Mmus       ----------------------------------------SPS
MSK1_Mmus       -------EGSNPDTL------------------F--Q---FSD
C54G4.1_Cele    -------SGTI----------------------R-ETRGSDSS
JIL1_Dmel       -------RVQP-ERA------------------RAMRQLYQFQ
MSK_Spur        STEQPSIPMTVPRTLHQPHPHPLPLPHQHLSHLPTISEDPSTT
AqueK023_Aque   --------LEI------------------------TDLKSATN