PCTAIRE3_Hsap MI----------------------------------------------------------
PCTAIRE2_Hsap ------------------------------------------------------------
PCTAIRE1_Hsap MP--------LYGRARDHVTHPSILGTRPG-RPMAGPITAAVPEKICNGAFCSCSGAFPL
PCTAIRE3_Mmus M-----------------------------------------------------------
PCTAIRE2_Mmus ------------------------------------------------------------
PCTAIRE1_Mmus MWGWCQRNMPFYGHTQDLVTSSSAL-TEPLVPTVAAAVTAATPEDSCCGVLCSHSETITL
ZC123.4_Cele MD----------------------------------------------------------
Pctaire_Spur M-----------------------------------------------------------
AqueK103_Aque ------------------------------------------------------------
PCTAIRE3_Hsap -----------------------MNKMKNFKRRFSLSVPRTET-I---------------
PCTAIRE2_Hsap --------------------------MKKFKRRLSLTLRGSQT-I---------------
PCTAIRE1_Hsap DPNNPSLGPLPSISHLNLRTQIAMDRMKKIKRQLSMTLRGGRG-I---------------
PCTAIRE3_Mmus ------------------------NKMKNFKRRLSLSVPRPET-I---------------
PCTAIRE2_Mmus --------------------------MKKFKRRLSLTLRGSQT-I---------------
PCTAIRE1_Mmus ETNNLMSGPLPSASHSSLSTQVAMDRMKKIKRQLSMTLRGGRG-I---------------
ZC123.4_Cele --------------------------LKSTKKTWKI--PSFNQMWGKITSHIGVWFGLEE
Pctaire_Spur ------------------------------------------------------------
AqueK103_Aque --------------------------MSAVKKRLSLTFGRTKS-R---------------
PCTAIRE3_Hsap -------EESLAE--FTEQF--------------------------NQLHNRRNENLQLG
PCTAIRE2_Hsap -------DESLSE--LAEQM--------------------------TIEENSSKDNEPIV
PCTAIRE1_Hsap -------DKTN-G--APEQI--------------------------GLDESGGGGGSDP-
PCTAIRE3_Mmus -------EESLAE--FTEQF--------------------------NQLHTQTNE-----
PCTAIRE2_Mmus -------DESLSE--LAEQM--------------------------TIEESSSKDNEPIV
PCTAIRE1_Mmus -------DKTN-G--VPEQI--------------------------GLDESGGGGGSDL-
ZC123.4_Cele AERPMRASCSLSMIHHPQLTAVRSSKSSENLH------------RITTMSPQRIQDVDGS
Pctaire_Spur ----------VEE--IPEIN--------------------------KIE-----------
AqueK103_Aque -------DHSYTG--IVDEG-----KTASNCLFVTTGIIAGAQDGFTKVEDEGAEVDAYP
:
PCTAIRE3_Hsap PLGRDPPQECSTF-----------------------------------------------
PCTAIRE2_Hsap KNGRPPTS-HSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLK
PCTAIRE1_Hsap --G-------------------------EAPTRAAPGELRSARG--PLSSAPEIVHEDLK
PCTAIRE3_Mmus ------------------------------------------------------------
PCTAIRE2_Mmus KNGRPPTS-HSVHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLK
PCTAIRE1_Mmus --G-------------------------EAPTRIAPGELRSVRG--PLSSAPEIVHEDMK
ZC123.4_Cele PSTRKPSS--SIFT----LRRSRNKE-KKYKNNGGGGSTKSPISKNGTNEMTQSWHSN--
Pctaire_Spur ------------------------------------------------------------
AqueK103_Aque TDGPLPAA--TLRSKTTRYS------------------------------RADNEHKRFT
PCTAIRE3_Hsap ------SPT-DSGEEPGQLSPGVQ-FQR-------RQNQRRFSMEVRASGALPRQVAGCT
PCTAIRE2_Hsap MGSDGESDQASGTSSDEVQSPTGV-CLR-------NRIHRRISM----------------
PCTAIRE1_Hsap MGSDGESDQASATSSDEVQSPVRV-RMR-------NHPPRKIST----------------
PCTAIRE3_Mmus ----------DGTDEPEQLSPGMQ-YQQ-------RQNQRRFSM----------------
PCTAIRE2_Mmus MGSDGESDQASGTSSDEVQSPTGV-CLR-------NRIHRRISM----------------
PCTAIRE1_Mmus MGSDGESDQASATSSDEVQSPVRV-RMR-------NHPPRKIST----------------
ZC123.4_Cele -HVNGASSGSGSGSTPEHHNKNIFSFLSRQSRSRSNNPSETMST----------------
Pctaire_Spur -------------------SP---------------------GD----------------
AqueK103_Aque LPLFGGSLGRSASSSNVDMSTI--------------SPERSLATS-------SKA-K---
. .
PCTAIRE3_Hsap HKGVHRRAAALQPDFDVSKRLSLPMDIRLPQEFLQKLQMESPDLPKPLS-----------
PCTAIRE2_Hsap --------------EDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMS-----------
PCTAIRE1_Hsap --------------EDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLS-----------
PCTAIRE3_Mmus --------------EDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLT-----------
PCTAIRE2_Mmus --------------EDLNKRLSLPADIRIPDGYLEKLQISSPPFDQPMS-----------
PCTAIRE1_Mmus --------------EDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLS-----------
ZC123.4_Cele --------------VPL--------------------NKNSPSMPPPPSSNTVADFTHLR
Pctaire_Spur --------------RDISKRLSLPVDMRLPEQFIEKYSLS-PPFEK-MS-----------
AqueK103_Aque ---------AK-SSFDL--------TVSPPV----SPTDGKPIFMPFAN-----------
: * : .
PCTAIRE3_Hsap -RMSRRASL----------SDIGF-GKLETYVKLDKLGEGTYATVFKGRSKLTENLVALK
PCTAIRE2_Hsap -RRSRRASL----------SEIGF-GKMETYIKLEKLGEGTYATVYKGRSKLTENLVALK
PCTAIRE1_Hsap -RRLRRVSL----------SEIGF-GKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALK
PCTAIRE3_Mmus -RMSRRASL----------SDIGF-GKLETYVKLDKLGEGTYATVFKGRSKLTENLVALK
PCTAIRE2_Mmus -RRSRRASL----------SEIGF-GKMETYIKLEKLGEGTYATVYKGRSKLTENLVALK
PCTAIRE1_Mmus -RRLRRVSL----------SEIGF-GKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALK
ZC123.4_Cele RRRPRSAHYDPNTITLPAKEEVTPQDVNDLYKRIDKLGEGSYATVYKCESKLDGSIVALK
Pctaire_Spur -RRSRRASL----------SEIGF-GKMETYTKLDKLGEGTYATVFKGRSRLTDNLVALK
AqueK103_Aque -RMQRRASL----------SEIGF-GKLQTYEKLEKLGEGTYATVYKGKSNITGKLVALK
* * . .:: . : * :::*****:****:* .*.: .:****
PCTAIRE3_Hsap EIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC
PCTAIRE2_Hsap EIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDC
PCTAIRE1_Hsap EIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC
PCTAIRE3_Mmus EIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC
PCTAIRE2_Mmus EIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDC
PCTAIRE1_Mmus EIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC
ZC123.4_Cele EIKLQFQEGLPFTAIREASLLRNLRHANIVSLHDIFYQHHQLTFVFEYMKMDLSKYLEQN
Pctaire_Spur EIRLEHEEGAPCTAIREVSLLKGLKHHNIVTLHDIVHTEKALTLVFEYLEKDLKQYMDDC
AqueK103_Aque EIRLEHEEGAPCTAIREVSLLKDLKHANIVFLHDIIHTARSLTLIFEYVEQDLKQYLDQC
**:*:.:** * *****.***:.*:* *** ***:.: : **::***:. **.:*::.
PCTAIRE3_Hsap GNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVP
PCTAIRE2_Hsap GNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVP
PCTAIRE1_Hsap GNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIP
PCTAIRE3_Mmus GNLMNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVP
PCTAIRE2_Mmus GNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINERGELKLADFGLARAKSVP
PCTAIRE1_Mmus GNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIP
ZC123.4_Cele VYGLDSIDIKLLLFQLLRGLDFCHRKKILHRDLKPQNLLLDEDGVLKLADFGLARAKSVP
Pctaire_Spur GSIMNMNNVKLFLFQLLRGLAYCHKRQVLHRDLKPQNLLINEKGELKLADFA--------
AqueK103_Aque SGMMAMPNVKLFLFQLMRGLQYCHSRKILHRDLKPQNLLISEQGDLKLADFGLARAKSVP
: ::*::::*::*** :** :::***********:.* * ******.
PCTAIRE3_Hsap TKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGST------VK
PCTAIRE2_Hsap TKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGST------VE
PCTAIRE1_Hsap TKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGST------VE
PCTAIRE3_Mmus TKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCILYEMATGKPLFPGST------VK
PCTAIRE2_Mmus TKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGST------VE
PCTAIRE1_Mmus TKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGST------VE
ZC123.4_Cele SRTYSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCIFAEICTGAALFPGSKDSHYPGTK
Pctaire_Spur -NVFSPHLVSSLERSRNAVLPNTIFL--FCTRGVGCIFYEMSAGRPLFPGST------VE
AqueK103_Aque TKTYSNEVVTLWYRPPDVLLGSIDYADSIDMWGVGCIFYEMIVGRPMFPGAN------VE
..:* .:*: *. : :: . : : ***** *: * .:***:. .:
PCTAIRE3_Hsap EELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPR---LDTDGIHLLSS
PCTAIRE2_Hsap DELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPR---LDSEGIELITK
PCTAIRE1_Hsap EQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPR---LDSDGADLLTK
PCTAIRE3_Mmus EELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYLPQPLLSHAPR---LDTEGINLLSS
PCTAIRE2_Mmus DELHLIFRLLGTPSQETWPGVSSNDEFKNYNFPKYKPQPLINHAPR---LDSEGIELITK
PCTAIRE1_Mmus EQLHFIFRILGTPTEETWPGILSNEEFRTYNYPKYRAEALLSHAPR---LDSDGADLLTK
ZC123.4_Cele DQLDMIFSIRGTPDEKKWPEVKTLPGYTPELFPRYRELSFIAVNPMFTKILKTGQELLGM
Pctaire_Spur DELHLIFKFLGTPDDKTWPGISANEDFVSYGFPGYPKEPVVTHAPR---LDLQCQDLLED
AqueK103_Aque EELVLIWKSLGTPNEKTWPGITKNKEFISHSFLRYDPQPLGLIVPR---LDKEGINLMSK
::* :*: *** ::.** : : : * .. * : .*:
PCTAIRE3_Hsap LLLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASIFSLKEIQLQKDPGYRGLAF-QQP
PCTAIRE2_Hsap FLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSY-PET
PCTAIRE1_Hsap LLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSM-PDS
PCTAIRE3_Mmus LLLYESKSRMSAEAALNHPYFQSLGDRVHQLHDTASIFSLKEIQLQKDPGYRGLAF-QHP
PCTAIRE2_Mmus FLQYESKKRVPAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSY-PET
PCTAIRE1_Mmus LLQFEGRNRISAEDARKHPFFLSLGERIHKLPDTTSIFALKEVQLQKEANIRSTSM-PDS
ZC123.4_Cele LLQLRPESRVSAASAMLHPYFASFPREVHLLAPSQSIFRLKELKDLR-------------
Pctaire_Spur LLKYEGKNRVSAAKAMRHPCFNCFGSKIHTLRDVQSIMDLPECQLSRDPGIRSSAV-PST
AqueK103_Aque LLSYESQERLLARDGMKHNYFSSLPPQIHDLPHIVSIFTIPGVELVKNPGDRKSQKDTKT
:* . ..*: * . * * .: .:* * **: : : :
PCTAIRE3_Hsap GR----------------------------------------------------------
PCTAIRE2_Hsap GH----------------------------------------------------------
PCTAIRE1_Hsap GR----------------------------------------------------------
PCTAIRE3_Mmus GR----------------------------------------------------------
PCTAIRE2_Mmus GH----------------------------------------------------------
PCTAIRE1_Mmus GR----------------------------------------------------------
ZC123.4_Cele ------------------------------------------------------------
Pctaire_Spur APIHTVIPNPLLAPIHTVRSNPLLAPIHTVIPNPLLAPIHTVIPNPLLAPIHTAPLVGDA
AqueK103_Aque SY----------------------------------------------------------
PCTAIRE3_Hsap -------------------GKNRRQ-SIF
PCTAIRE2_Hsap -------------------GKNRRQSMLF
PCTAIRE1_Hsap -------------------PAFRVVDTEF
PCTAIRE3_Mmus -------------------GKSRRQ-SIF
PCTAIRE2_Mmus -------------------GKNRRQSMLF
PCTAIRE1_Mmus -------------------PAFRVVDTEF
ZC123.4_Cele ---------------------------SL
Pctaire_Spur RACTFNVTTDFKINDCDEASKFAVTDFIM
AqueK103_Aque -------------------DRDRRRSSLY