PFTAIRE2_Hsap   YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIRE-----ASLLKGLK
PFTAIRE1_Hsap   YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIRE-----ASLLKGLK
Eip63E_Dmel     YVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIRE-----ASLLKELK
PFTAIRE2_Mmus   YLNLEKLGEGSYAKVYKGISRINGQLVALKVISMNAEEGVPFTAIRE-----ASLLKGLK
PFTAIRE1_Mmus   YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIRE-----ASLLKGLK
pct-1_Cele      YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQEEGAPCTAIRE-----VSLLRNLR
Pftaire_Spur    YKKICPLGEGSYAKVYKAVSCINQQVVALKEIRLQQDEGTPFTAIRE-----ASLLKDLK
AqueK104_Aque   YKKLEALGEGSYATVYKGISIANGHYVALKEIRLNSEEGTPFTAIREGIMTFASLLKGLK
                * ::  ****:**.*::. *  . : **** * :: :**.* *****     .***: *:

PFTAIRE2_Hsap   HANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHH
PFTAIRE1_Hsap   HANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQ
Eip63E_Dmel     HSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHK
PFTAIRE2_Mmus   HANIVLLHDIVHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHH
PFTAIRE1_Mmus   HANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQ
pct-1_Cele      HANVVTLHDIIHTDRLLTLVFEYVDRDLKQYMDSCNNAMQMNNIRLFLYQLLRGLAYCHQ
Pftaire_Spur    HANIVCLHDIIHTKTTLSFVFEYVHTDLSTYLERHPGGLNPNNVRLFLFQLIRGLSFCHK
AqueK104_Aque   HANIVILHDIIHTSNNLTFVFEYVDTDLSRYMEKHPGPLDPRNVKILLIQLLRGLNFCHR
                *:*:* ****:**   *::****:. **  *:.   . :.  *::::: **:*** : *:

PFTAIRE2_Hsap   QHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEY
PFTAIRE1_Hsap   RYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEY
Eip63E_Dmel     RRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEY
PFTAIRE2_Mmus   QRVLHRDLKPQNLLLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEY
PFTAIRE1_Mmus   RYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEY
pct-1_Cele      RRVLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDY
Pftaire_Spur    RKILHRDLKPQNLLISEAGELKLADFGLARAKSIPSRTYSHEVVTLWYRPPDVLMGSTDY
AqueK104_Aque   RKILHRDLKPQNILLNHNGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDY
                : :****:****:*:.  ***************:*::*** ***********.*:*:*:*

PFTAIRE2_Hsap   SSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPE
PFTAIRE1_Hsap   STCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPE
Eip63E_Dmel     STSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPH
PFTAIRE2_Mmus   SSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPE
PFTAIRE1_Mmus   STCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPE
pct-1_Cele      STHIDMWGVGCILFEMIAGRALFPGGTP-TEQLGLIFRTLGSPRPDRHPTICEKPTFYPY
Pftaire_Spur    STQLDIWGVGCIFLEMMWGQPAFPGLKDATDQLEKIFKVLGTPTEQTWHGVSRLPNYGKV
AqueK104_Aque   FTSLDMWGVGCIFVEMLTGKPLFPGLKGVYDQLNRIWSILGTPNNTTWPGVTDLPEYRPE
                 : :*:**.***:.**. * . ***     :**  *:  ** *       :   * :

PFTAIRE2_Hsap   W--FPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYF
PFTAIRE1_Hsap   R--FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
Eip63E_Dmel     K--LGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYF
PFTAIRE2_Mmus   W--FPPPKPQSLQIVWDRLGGVPEAEDLASQMLKGFPRDRVSAQEALVHDYF
PFTAIRE1_Mmus   R--FTVYSSKSLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
pct-1_Cele      A--NRHYNPDPLCRQIPRID--AHGFELLMKFLQYEGKDRVSAAEAVKHPFL
Pftaire_Spur    AAAGRFHKPKLLCEILPSILLIPGAESLMTDMLQLEPRKRISTVQAMTCQYF
AqueK104_Aque   Q--YEQCPPLGLEVVAPILHPKTKVGDLAMKLLQLIPSNRITADDALAHEYF
                        .  *      :        :   :*:    .*: :  *:   ::