Gene 88200.m00281 (T.vaginalis)

88200.m00281

Species: T.vaginalis
Alias: 88200.m00281, TvagK0822
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
88200.m00281.AA Protein None 338 None Fasta, JSON
88200.m00281.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of 88200.m00281.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 88200.m00281.AA S_TKc 43-324 24 2.2e-54 187.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 43-324
Range on HMM: 1-231/231
Sequence Identity: 24% (74 aa)

LKFGKCIGDGHFSHVYQGWYRN-QLPCAIKVLERGDKQLINNEISLLQELNGEPNIVQLYDVHRDDVTVLVFELIHS--YPLDDLFAY---------ITV
 .... || | |. ||... .. .  .|||..     . | .||..|..  . ||||.|||| .||   .|.|..      | |.            .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

DEIRKLVYGLLVALQAAHKHGIVHRDLKIANIMASKDLSVVKLIDWGCGGRVIEGKMLVKAGSRLCRSPEMLLEDPNYGF-GCDIWAVGILILDILTNGR
 ..|...| .. ||.  |.|||.||||| .||. ..   ..|..| |   ..         |..  ..||.|     ||.  ||.|..|...   |. |.
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC-GY

IPWKAKTGSEILVLISQFFGKKQIVDIVERAKIPYPRKLNPNDLHENPTKDLLYSLDPANFQLYDSKLLDLMFKLLTIDPELRPTATEALA-------HD
 |.   .  ... .|                                                 .. ..|.. |.|. ||| |||| |||.       | 
PPFP--QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

FF
.|
WF
Kinase 88200.m00281.AA CK2 44-324 28 3.8e-54 159.64 In-house 2-288 (288) Show / Hide 
Range on Protein: 44-324
Range on HMM: 2-288/288
Sequence Identity: 28% (83 aa)

KFGKCIGDGHFSHVYQGWYRNQLP-C--AIKVLERGDKQLINNEISLLQELNGEPNIVQLYDVHRDD---VTVLVFELIHSYPLDDLFAYITVDEIRKLV
. .. || | .| |..|   .    |   ||.|    |. |  ||. |..||| |||..|||. .|    |. |||| .       |.  .|  .||  .
EVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYYM

YGLLVALQAAHKHGIVHRDLKIANIMASKDLSVVKLIDWGCGGRVIEGKM-LVKAGSRLCRSPEMLLEDPNYGFGCDIWAVGILILDILTNGRIPWKAKT
. || ||  .|. ||.||| | .|||      . .|||||       |.   |. .||  . ||.|...  | .  |.|..|...  .. .     . . 
FELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGHD

GSEILVLISQFFGKKQIVDIVERAKIPYPRKLNPNDLHENPTKDLLYSLDPANFQLYDSKLLDLMFKLLTIDPELRPTATEALAHDFF
  . || | . .| . ... ... .|. ... . . ....  | .    .  | .| . . .|.. |.| .|.. | || ||. | .|
NYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFH-DIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 88200.m00281.AA CMGC 43-324 14 1.3e-45 147.25 In-house 1-513 (513) Show / Hide 
Range on Protein: 43-324
Range on HMM: 1-513/513
Sequence Identity: 14% (77 aa)

LKFGKCIGDGHFSHVYQGWY---------------RNQLPCAIKVL----ERGDKQ----------LINNEISLLQELN----------------GEPNI
 .  | || |... ||...                ...  .||| .    .  ...           .. ||..|..||                 ..||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VQLYDVHRDD------------------VTVLVFELIHS--------YP----------LDDLF-------------AYITVDEIRKLVYGLLVALQ--A
|.|||. ...                     ||||..          ..          |..                |...  ||   | .| .|    
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

AHKHG--IVHRDLKIANIMASKDLSV-------------------VKLIDWGCGGRVIEG-----------------------KMLVKAGSRLCRSPEML
 |.|.  |.||||| .||. ...  .                   .|..|.|    . .                         .     .|  |.|| |
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LED---------PNYGFGCDIWAVGILILDILTN-------GRIPWKAKTG-----------SEILVLISQFFG------------------KKQIVDIV
| .          .|. ..|.|.||  .  ..|.       |.. .. ...            . | .| . .|                  .... ...
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

E-------------------RAKIPYPRKLNPNDLHENPTKDLLYSLDPANF------------------------------QLYDSKLLDLMFKLLTID
.                     .  .  . ..|.. . | |..     ....                               . |....||. |.|..|
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

PELRPTATEALAHDFF
|. |.|| .||.|..|
PDKRITAEQALQHPYF
Kinase 88200.m00281.AA CAMK 48-241 19 5e-41 129.46 In-house 1-343 (425) Show / Hide 
Range on Protein: 48-241
Range on HMM: 1-343/425
Sequence Identity: 19% (66 aa)

CIGDGHFSHVYQGWYR-NQ------------LPCAIKVLERG-------------------------------DKQLINNEISLLQELNG------EPNI
 .| | |. |. .  . ..              .|||....                                |.. . .||.... |.|       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYDVHR--------------------DDVTVLVF---ELIHSYPL-DDLFAYITVD---------------------EIRKLVYGLLVALQAAHKHGI
..||.|                      |.  ..|.   |..    | |||| ||.                       | |...  .. |..  |.|.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKIANIMASKDL----------------SVVKLIDWGCGGRVIEGK-------------------------MLVKAGSRLCRS-PEMLLE------
||||||  ||. ...                   .|.||.|   ....|.                         |    |.    . ||.|.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------DPNYGFGCDIWAVGILILDILTNGRIPWKAKTGSEIL
        | ||. ||.|..|. || |.  |. |. .....||.
QNATDEEKPYYGPKCDMWSCGV-ILYIMLCGYPPFYGDCDNEIC
Kinase 88200.m00281.AA Pkinase 43-324 24 8.7e-41 145.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 43-324
Range on HMM: 1-293/293
Sequence Identity: 24% (77 aa)

LKFGKCIGDGHFSHVYQGWYRNQ-LPCAIKVLERGDKQLINN-------EISLLQELNGEPNIVQLYDVHR-DDVTVLVFELI-HS-YPLDDLFAYIT--
...|..|| | |. ||..  ..     |.|.... ..    .       ||.....| . ||||.|||. . .|   .|.|.  .  | . |||.||.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTW

----V----DEIRKLVYGLLVALQAAHKHGIVHRDLKIANIMASKDLSV---VKLIDWGCGG---RVIEGKMLVKAGSRLCRSPEMLLEDPNYGFGCDIW
    .    .|... .| .| .|.  |..||.||||| .||. ...  .   ||..|.|.         . | . .|..  ..|| ..... ||  .|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

AVGILILDILTNGRIPWKAK----TGSEILVLISQFFGKKQIVDIVERAKIPYPRKLNPNDLHENPTKDLLYSLDPANFQLYDSKLLDLMFKLLTIDPEL
..|...   |. || |.. .    .  . ...| .  |..   |. .   |.|   ... . |            .  | . .. ..|.. ..|. ||. 
SCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------F-HWTFHNWSEECKDFIKWCLCKDPKK

RPTATEALAHDFF
||||...| |..|
RPTAEQILQHPWF
Kinase 88200.m00281.AA Ciliate-E2 43-324 18 2e-33 112.12 In-house 1-365 (365) Show / Hide 
Range on Protein: 43-324
Range on HMM: 1-365/365
Sequence Identity: 18% (74 aa)

LKFGKCIGDGHFSHVYQG--WYRNQLP----------------------CAIKVLERGDKQLINNEISLLQELN---------------GEPNIVQLYDV
 || |.|| | |. ||..  |  ...                        |.|...  ... |..||....|.|                 |||...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

HR---DDVTVLVFELIHSYPLDD------LFA--------YITVDEIRKLVYGLLV---------------ALQAAHKHG-IVHRDLKIANIMASKDLSV
     |.   ||.|..    | |      ..         |.|  ||... . .|                ||.  |. . |.|||.|  ||.       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VKLIDWGCGGRVIEG----------KMLVKAG------------------------SRLCRSPEMLLEDPN--------YGFGCDIWAVGILILDILTNG
.|.||.|   .. .           |..   .                        .    .||.|   ..        |.. ||||..|...  ..  |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY-EMLFG

RIPWKAKTGSEILVLISQFFGKKQIVDIVERAKIPYPRKLNPNDLHENPTKDLLYSLDPANFQLYDSKLLDLMFK----LLTIDPELRPT-ATEALAHDF
. |.                      .. .  || .| . . .| .  .   . .     ...  . .  ||. |    .|  ||| |.| . ..| | .
KPPF---------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-QCKW----KSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPW

F
|
F
Kinase 88200.m00281.AA STE 43-324 20 1.3e-28 98.26 In-house 1-359 (359) Show / Hide 
Range on Protein: 43-324
Range on HMM: 1-359/359
Sequence Identity: 20% (80 aa)

LKFGKCIGDGHFSHVYQGWYRN----------------QLPCAIKVLE--------------------RGDKQLINNEISLLQELNG-EPNIVQLYDVHR
... ..|| | |  ||.. ...                .  .|||...                      ..| | .||......|   ||||. |. . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

--------DDVTVLVFELIHSYPLDDLFA-----------------YITVDEIRKLVYGLLVA-LQAAHKHGIVHRDLKIANIMASKDLSVVKLIDWGCG
        ||   .. |..    |||.                   ..  ..|.. .. .| . |.  |.|.|.|||.| |||.       |||.| |. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFGVC

GRVIE------------------GKMLVKAGSRLCRSPEMLLE-----DPNYGFGCDIWAVGILILDILTNGRIPWKAKTGSEILVLISQFFGKK----Q
|....                  .|    .|.    .||...      |. |.. |||| .|..|.  .| |. ||   .  . . .| . ...     |
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMAT-GKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

IVDIVERAKIPYPRKLNPNDLHENPTKDLLYSLDPANFQ--------LYDSKLLDLMFKLLTIDPELRPTATEALA--HDFF
.  ||.    | | .| .|..  .           .  .         . ... | . | |..||. ||||.. |   | |.
L-CIVNGPPPPLPDHLSQNEM-IS-----------Y--GGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 88200.m00281.AA Ciliate-E2-Unclassified 44-324 17 9.7e-24 79.24 In-house 2-352 (352) Show / Hide 
Range on Protein: 44-324
Range on HMM: 2-352/352
Sequence Identity: 17% (66 aa)

KFGKCIGDGHFSHVYQGWYRNQLPC-----AIKVLERGDKQL-----INNEISLLQELN------------------GEPNIVQLYDVHRDD-VTVLVFE
|..|.|| | |. ||.   ..|        ..|. .. .||      |.||.  .....                    |.|| .... .|.    .| |
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVME

LIHSYPLDDLFA--------------------YITVDEIR-----KLVYGLLVALQAAHKHG-IVHRDLKIANIMASKDLS--VVKLIDWGC--------
..    | .                        .|  ...     .. . .|..|.  |. . |.|||.|  ||. ... .   .|.||.|         
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

---------GGRVIEGKMLVKAGSRLCR----SPEMLLEDPNYG---FGCDIWAVGILILDILTNGRIPWKAKTGSEILVLISQFFGK----KQIVDIVE
          .. .. .|  ..|.        .||.| .  ...   . ||||..|...  .|..   | ....  .  .||.|.       ||. ..  
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIK

RAKIPYPRKLNPNDLHENPTKDLLYSLDPANFQLYDSKLLD-LMFKLLTIDPELRPTATEALAHDFF
  .| .|   . .              .| . .     ..  |. |.|  .|. |.|. ..| | .|
QKNIQFPKFPWQQ--------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 88200.m00281.AA CAMKL 43-220 26 2.9e-21 64.47 In-house 1-225 (297) Show / Hide 
Range on Protein: 43-220
Range on HMM: 1-225/297
Sequence Identity: 26% (59 aa)

LKFGKCIGDGHFSHVYQGWY-RN-QLPCAIKVLERGDKQL------------------INNEISLLQELN--GEPNIVQLYDVHRDDV-------TVLVF
 ..|| .| |.|. |  ..  |. .   |||....  ...                  |  ||.... ||  . |||..||.|  ..         .|| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELIHSYPLDDLFAYI----------TVDEIRKLVYGLLVALQAAHKHGIVHRDLKIANIMASKDLS-VVKLIDWGCGGRVIE-----GKMLVKA-GSRLC
|.. .    ||| ||          . .| |..   .. |..  |.|||||||.|  ||. ... . ..|.|| | .   ..     |..|    ||   
EYCSGGE-MDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

RSPEMLLE--DPNYGFGCDIWAVGIL
 .||...   .| .|.  |||. |..
MAPEIFQGNNKPYDGPKVDIWSCGVI
Kinase 88200.m00281.AA CDK 84-175 32 1e-15 46.62 In-house 58-156 (284) Show / Hide 
Range on Protein: 84-175
Range on HMM: 58-156/284
Sequence Identity: 32% (35 aa)

EISLLQELNGEPNIVQLYDVHRDD------------VTVLVFELIHSYPLDDLFAYITVDEIRKLVYGLLVALQAAHKHGIVHRDLKIANIMASKDLS--
|||||.||   ||||.|.||  ..              ..||| ..     ||  |.    |. . . || .|   |...|.||||| .||. ... .  
EISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDH----DLKKYMD---IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK

--VVKLID
  ..|. |
CGRLKIAD
Kinase 88200.m00281.AA CDC2 84-177 32 4.1e-15 42.37 In-house 50-148 (301) Show / Hide 
Range on Protein: 84-177
Range on HMM: 50-148/301
Sequence Identity: 32% (32 aa)

EISLLQELNGEPNIVQLYDVHRDDVTVLVFELIHS---YPLDDLFA---YITVDEIRKLVYGLLVALQAAHKHGIVHRDLKIANIMASKDLSVVKLIDWG
|||.|.||.  ||||.| ||       .||| ..    . .| ..    ..... .... | .| ..   | ..|.|||||. ||  .|. . .|. | |
EISCLKELKDHPNIVKLHDVIHQNKLYMVFEYLDMDLKKYMDMSIPKNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFG
Kinase 88200.m00281.AA TyrKc 43-324 18 2.6e-12 -23.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 43-324
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

LKFGKCIGDGHFSHVYQGWYRNQLPCAIKVLERGDKQLINNEISLLQEL-NGEPNIVQLYDVHRD--------DVTVLVFELIHSYPLDDLF----AYIT
...|| .| |.|  ||.| ..  ...|.|.|  . .. . .|.... .|    ||||.|| | ..        .   .|.|.     |.|        ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

VDEIRKLVYGLLVALQAAHKHGIVHRDLKIANIMASKDLSVVKL------IDWGCG---GRVIEGKMLVKAGSRLCR--------SPEMLLEDPNYGFGC
...  .  .      .  |.....||||   |.. .... .||        |.. .   |   .... .|.... ..        .|| .  .  . .  
MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKS

DIWAVGILILDILTNGRIPWKA-----KTGSEILVLISQFFGKKQIVD---IVERAKIPYPRKLNPNDLHENPTKDLLYSLDPANFQLYDSKLLDLMFKL
|.|. |...  |.|.|  |.       .. .|.. .. | .  .|  .   .                                 |    ... ..| . 
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------FVCCPDEMYQIMKQC

LTIDPELRPTATEALAHDFF
   ||| ||| .|   |..|
WHEDPEDRPTFSEI--HECF
Kinase 88200.m00281.AA CDK 290-324 37 5.3e-10 28.02 In-house 255-284 (284) Show / Hide 
Range on Protein: 290-324
Range on HMM: 255-284/284
Sequence Identity: 37% (13 aa)

FQLYDSKLLDLMFKLLTIDPELRPTATEALAHDFF
...|     ||. |.|. ||. | .|..|| |..|
LPDY-----DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 88200.m00281.AA CDKL 295-324 40 8.1e-10 29.74 In-house 257-286 (286) Show / Hide 
Range on Protein: 295-324
Range on HMM: 257-286/286
Sequence Identity: 40% (12 aa)

SKLLDLMFKLLTIDPELRPTATEALAHDFF
.|.||.| |.| .||  |.|..... |..|
KKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 88200.m00281.AA Pkinase_Tyr 43-101 30 3.1e-09 31.9 Pfam 1-70 (270) Show / Hide 
Range on Protein: 43-101
Range on HMM: 1-70/270
Sequence Identity: 30% (22 aa)

LKFGKCIGDGHFSHVYQGWYR-----NQLPCAIKVL--ERGDKQ-----LINNEISLLQELNGEPNIVQLY
..||| .| |.| .||.| ..     ...|.|.|.|     ..|     ... |.... .|   ||||.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLY
Kinase 88200.m00281.AA CAMK 299-324 42 1.1e-08 23.31 In-house 400-425 (425) Show / Hide 
Range on Protein: 299-324
Range on HMM: 400-425/425
Sequence Identity: 42% (11 aa)

DLMFKLLTIDPELRPTATEALAHDFF
||  |.|. ||| |.|....|.| ..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 88200.m00281.AA CDC2 298-324 44 5.2e-08 20.15 In-house 275-301 (301) Show / Hide 
Range on Protein: 298-324
Range on HMM: 275-301/301
Sequence Identity: 44% (12 aa)

LDLMFKLLTIDPELRPTATEALAHDFF
.||  ..| .||. | .| |||.| .|
IDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 88200.m00281.AA CDKL 197-218 54 2.1e-07 21.35 In-house 166-187 (286) Show / Hide 
Range on Protein: 197-218
Range on HMM: 166-187/286
Sequence Identity: 54% (12 aa)

RSPEMLLEDPNYGFGCDIWAVG
|.|| |. |. ||   ||||.|
RAPELLVGDTQYGKPVDIWAIG
Kinase 88200.m00281.AA CDKL 111-177 38 3e-06 17.27 In-house 75-144 (286) Show / Hide 
Range on Protein: 111-177
Range on HMM: 75-144/286
Sequence Identity: 38% (27 aa)

LVFELIHSYPLDDLFAYIT-VD--EIRKLVYGLLVALQAAHKHGIVHRDLKIANIMASKDLSVVKLIDWG
|||| .    |..|  | . ||   .|| .. .| |..  ||| ..||| |  ||  .   ..||| | |
LVFEYCDHTVLHELEEYPNGVDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFG
Kinase 88200.m00281.AA CAMKL 294-324 32 1.2e-05 13.79 In-house 268-297 (297) Show / Hide 
Range on Protein: 294-324
Range on HMM: 268-297/297
Sequence Identity: 32% (10 aa)

DSKLLDLMFKLLTIDPELRPTATEALAHDFF
.  . ||  |.|. .|| |||. . . | ..
S-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 88200.m00281.AA CDC2 197-218 40 0.000722 7.19 In-house 172-193 (301) Show / Hide 
Range on Protein: 197-218
Range on HMM: 172-193/301
Sequence Identity: 40% (9 aa)

RSPEMLLEDPNYGFGCDIWAVG
|.|| || .  | .. |.|..|
RAPEILLGCKRYSTPVDMWSIG
Kinase 88200.m00281.AA CDK 197-218 41 0.001451 7.09 In-house 186-209 (284) Show / Hide 
Range on Protein: 197-218
Range on HMM: 186-209/284
Sequence Identity: 41% (10 aa)

RSPEMLLEDPNYG--FGCDIWAVG
|.|| || . .|.   . |.|.||
RAPELLLGSKHYSGGTPIDMWSVG