Gene 81840.m00170 (T.vaginalis)

81840.m00170

Species: T.vaginalis
Alias: 81840.m00170, TvagK0712
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
81840.m00170.AA Protein None 328 None Fasta, JSON
81840.m00170.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of 81840.m00170.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81840.m00170.AA CK2 36-320 50 9.40000000001e-145 435.49 In-house 1-288 (288) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-288/288
Sequence Identity: 50% (145 aa)

YELCYRIGRGKYSTVFSGLTNTGQQ-C--VLKVLKPVRASKINREIRILEKLKESPNICNLLDVVKDQESQMVTLVLDWTND-DFRNIYQTLEMNEIAYY
||.  .||||||| ||.|.  . .. |  | |.||||.  || |||.|||.|.  ||| .|.|.|||. |..  || .. |. |||..||||.  .| ||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

MYKVLQALDFAHSRGIMHRDIKPQNIMIDHSTKKVSLIDWGLADFYVPGTAYQVRVATRNYKAPELLFGYTQYTPTVDIWGLGCTFAAMLTKKSPLFRGR
|...|.|||..|| ||||||.||.||||||. .| .|||||||.|| ||. | ||||.|.||.||||  | .| . .|.| ||| ||.|. || |.|.| 
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DNSELILRIADFIGSEEIENYLQKYKITISSHDITSRISGHKRRAHEFLKKDDTKNFITPEAEDLLMKMLTVDHQERISAKDAMMHPFF
|| .  ..|.  .| |.. .||.||.|.. .. . . .  ||..  | . ....|.  .||| |.| |||  ||||||.||.|| ||.|
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQ-FHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 81840.m00170.AA CMGC 36-320 18 6.3e-86 282.22 In-house 1-513 (513) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-513/513
Sequence Identity: 18% (96 aa)

YELCYRIGRGKYSTVFSG---------------LTNTGQQCVLK--------------VLKPVRASKINREIRILEKLK----------------ESPNI
||   .||.| |..|...               ...|.... .|              ..|..  ....|||.||..|.                  .||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

CNLLDVVKDQESQ---------------MVTLVLDWTNDDFRNIYQT------------LEMNE------------IAYYM------YKVLQALD--FAH
 .|.|.... .|.                . || .    |  .. .             |.  .            | |.|      | .|..|.  . |
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

SRG--IMHRDIKPQNIMIDHSTKK-------------------VSLIDWGLADFYVPG----------------------TAYQVRVATRNYKAPELLFG
|..  |.|||.||.||.|.| ..                    . ..|.||| .| |                        .|  .|.|| |.|||.|.|
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

YTQYT---------PTVDIWGLGCTFAAMLTK-------KSPLFRGRDN-----------SELILRIADFIG------------------SEEIENYLQK
...||         ...|.|..|| || |.|.       . ||| |...            . . .| . .|                  .||. |....
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL

YKI--------------TISSHDITSRIS---GHKRRAHEFLKKDDTKNF--------------------------------ITPEAEDLLMKMLTVDHQ
.                ..|..  . . |     ... . . ..   ...                                ..|.| |||.|||. |..
PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD

ERISAKDAMMHPFF
.||.|..|. ||.|
KRITAEQALQHPYF
Kinase 81840.m00170.AA S_TKc 36-320 23 1.2e-68 235.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-231/231
Sequence Identity: 23% (73 aa)

YELCYRIGRGKYSTVFSGLTNT-GQQCVLKVLKPVRASKINREIRILEKLKESPNICNLLDVVKDQESQMVTLVLDWTND---DFRNIYQT---------
||.   ||.| ...|. .  .  |... .|..|     .| |||.||.|    |||..|.||  |   . . .|..  .    | . . .          
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LEMNEIAYYMYKVLQALDFAHSRGIMHRDIKPQNIMIDHSTKKVSLIDWGLADFYVPGTAYQVRVATRNYKAPELLFGYTQYTP-TVDIWGLGCTFAAML
.   ....||| ...||.. ||.||.|||.||.||..|.    . ..| ||| ..         . |..| |||.|    .|..  .|.| .||... ||
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TKKSPLFRGRDNSELILRIADFIGSEEIENYLQKYKITISSHDITSRISGHKRRAHEFLKKDDTKNFITPEAEDLLMKMLTVDHQERISAKDAMM-----
. . |      . ......                                                 .||| |...|.|..| ..|..| .|.      
CGYPPFP----QMQMMFKKIG-----------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--HPFF
  ||.|
KCHPWF
Kinase 81840.m00170.AA Pkinase 36-320 24 3.7e-63 220.94 Pfam 1-293 (293) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-293/293
Sequence Identity: 24% (77 aa)

YELCYRIGRGKYSTVFSG-LTNTGQQCVLKVLKPVRASKINR-------EIRILEKLKESPNICNLLDVVKDQESQMVTLVLDWTND-----DFR-----
|..  .||.| ...|. .   .||.. ..|..| .....  .       ||.|. .|  .|||. |.|.. | .. .  .|... .      |       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIY-MVMEYCEGGLYVMDLFDYIST

NIYQTL--EMNEIAYYMYKVLQALDFAHSRGIMHRDIKPQNIMIDHSTKKV----SLIDWGLADF--YVPGTAYQVRVATRNYKAPELLFGYTQYTPTVD
  . ..  ...|.  ||| .|..|.. ||.||.|||.||.||.|| ..  .     ..|.||| .  | ... ..... |..| |||.. |.. |.| ||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWGLGCTFAAMLTKKSPLFRGR------DNSELILRIADFIGSEEIENYLQKYKITISSHDITSRISGHKRRAHEFLKKDDTKNFITPEAEDLLMKMLTV
.|..||... ||... |.|.|.      |  ..| || . . ......   ..  .  .|   .          . ...  ..  ...|. |.. ..|..
MWSCGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----------F-HWTF-HN--WSEECKDFIKWCLCK

DHQERISAKDAMMHPFF
| ..|..|.... ||.|
DPKKRPTAEQILQHPWF
Kinase 81840.m00170.AA CDK 36-320 26 2.1e-61 195.16 In-house 1-284 (284) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-284/284
Sequence Identity: 26% (88 aa)

YELCYRIGRGKYSTVFSGLTNT-G-----QQCVLKVLKPVR-----A-SKIN----REIRILEKLKESPNICNLLDVVKDQESQ---------MVTLVLD
|| . .||.| | .|. .     |     | . || ..        .   ..    ||| .| .|   ||| .|.||. . ..           ...| .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

WTNDDFRNIYQTLEMNEIAYYMYKVLQALDFAHSRGIMHRDIKPQNIMIDHSTK----KVSLIDWGLADFYV-------PGTAYQVRVATRNYKAPELLF
    |   .        |  ||.  |..|.. ||..|||||.|||||.|..  .    .. . | |||  .        |  .|  .| |. | |||||.
YMDHDLKKYMD------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLL

GYTQYT--PTVDIWGLGCTFAAMLT--KKSPLFRGRDNSELILRIADFIGS---------EEIENYLQKYKITISSHDITSRISGHKRRAHEFLKKDDTK
| ..|.  ...|.|..|| || |.|   . ||| |.   . . .| ...|.         ..  .|                                  
GSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------------------

NFITPEAEDLLMKMLTVDHQERISAKDAMMHPFF
        |||.|||. | . ||||..|. ||.|
--------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 81840.m00170.AA CAMK 41-320 17 1.3e-55 177.3 In-house 1-425 (425) Show / Hide 
Range on Protein: 41-320
Range on HMM: 1-425/425
Sequence Identity: 17% (77 aa)

RIGRGKYSTVFSGLTN-TG------------QQCVLKVLK-------------------------------PVRASKINREIRILEKLKE------SPNI
 .||| ...|. .    |.            |..  |...                               |.   .. |||.|. ||..       |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CNLLDVVKDQE-----------------SQMVTLVL---DWTNDD------FRNIYQT-----------------LEMNEIAYYMYKVLQALDFAHSRGI
..|..|  | .                  ... .|.   .           |  | .                  ..  | ..|.  ...|... ||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDIKPQNIMIDHST----------------KKVSLIDWGLADFYVP------------------------GTAYQVRVATRNYKA-PELLFG------
.|||.|| ||..|..                  .. .||.|.| .. |                        |  .. .. |  | | ||.| |      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------YTQYTPTVDIWGLGCTFAAMLTKKSPLFRGRDNSELILRIADFIGSEEIENYLQKYKITISSHDITSRISGHKRR-AHEFLKK---------D
        . |.| .|.| .|.   .||. ..| |.| ...| .  .    . .          |. . ...  .|   | .  ......         .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP-FYGDCDNEICE-D----E-W----------IGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWW

D------TKNFITPEAEDLLMKMLTVDHQERISAKDAMMHPFF
|      .. |...|. ||. |||.|| ..|....... ||..
DDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81840.m00170.AA Ciliate-E2 36-320 17 1.4e-44 150.99 In-house 1-365 (365) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-365/365
Sequence Identity: 17% (72 aa)

YELCYRIGRGKYSTVFSG---LT---------------------NTGQQCVLKVLKPVRASKINREIRILEKLKE---------------SPNICNLLDV
|..   ||.| ...|. .   ..                     .....  .|..|.     |..||.|. ....               .|||... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VKDQESQMVTLVLDWTNDD--FRNIYQT-------------LEMNEIAYYMYKVLQ---------------ALDFAHSRG-IMHRDIKPQNIMIDHSTKK
 ...  . . ||..  .    |  |..              . ..||.|.|...||               || . ||.. |.||||||.||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VSLIDWGLADFYVP-----------GTAYQVR----------------------VATRNYKAPELLFG--------YTQYTPTVDIWGLGCTFAAMLTKK
. .||.||. .| .           .   . .                      . | .|.||| | |         ..|.  .||| ||...  ||..|
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

SPLFRGRDNSELILRIADFIGSEEIENYLQKYKITISSHDITSRISGHKRRAHEFLKKDDTK------------------NF--ITPEAEDLLMK----M
 |                                                   .  |. . .                  ..  ...|. ||. |    |
PPF-------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRM

LTVDHQERIS-AKDAMMHPFF
| .| ..||. ..... ||.|
LQKDPEKRITGWEQILNHPWF
Kinase 81840.m00170.AA CDK-Unclassified 75-246 30 1.9e-42 137.35 In-house 56-257 (324) Show / Hide 
Range on Protein: 75-246
Range on HMM: 56-257/324
Sequence Identity: 30% (62 aa)

NREIRILEKLKESPNICNLLDVVKDQESQM-----------VTLVLDWTNDDF----RNIYQTLEMNEIAYYMYKVLQALDFAHSRGIMHRDIKPQNIMI
.||| .|  ... ..|  ..|.. |                . .|..   ...     |    |.| .|  .|   |  . . |. .|||||||||||||
QREISCLQNCNHMNII-KFMDMHYDHDRCSKNPYYDNLHPSFYMVMEYMPYTWYNQLHNNRYNLSMCQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMI

DHST----KKVSLIDWGLADFYV-------------PGTAYQVRVATRNYKAPELLFGYTQYTPTVDIWGLGCTFAAMLTKKSPLFRGRDNSELILRIAD
.. .     .. ..| |.| ||              |.  | . |.|| |.|||||||  .|.. ||||..|| .| .. .| |.| ||   | .  | .
TNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGK-PIFQGRTEIEQMHHIFK

FIGS
 .|.
MLGT
Kinase 81840.m00170.AA CDC2 36-230 34 2.7e-42 127.44 In-house 1-211 (301) Show / Hide 
Range on Protein: 36-230
Range on HMM: 1-211/301
Sequence Identity: 34% (75 aa)

YELCYRIGRGKYSTVFSG-LTNTGQQCVLKVLKPVRASKIN-------REIRILEKLKESPNICNLLDVVKDQESQMVTLVLDWTNDDFRNIYQ------
|.   .|| | |  |. .  . |.|...||  .  . . .        ||| .| .||. |||  | ||..    . . .| .  . | ..         
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

-TLEMNEIAYYMYKVLQALDFAHSRGIMHRDIKPQNIMIDHSTKKVSLIDWGLA-DFYVPGTAYQ--VRVATRNYKAPELLFGYTQYTPTVDIWGLGCTF
  .. . .  |||. ||...| |.|.|||||.||||| || . . . . | ||| .| .|  .|     | |. | |||.|.|  .|. .||.| .||.|
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIF

AAM---LTKKSPLFRG
| |    ||| ||| |
AEMFMDVTKK-PLFHG
Kinase 81840.m00170.AA Ciliate-E2-Unclassified 36-320 17 2.8e-38 130.41 In-house 1-352 (352) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-352/352
Sequence Identity: 17% (68 aa)

YELCYRIGRGKYSTVFSGLT-NTG-----------QQCVLKVLKPVRASKINREIRILEK---------------LKESPNICNLLDVVKDQESQMVTLV
|.. . ||.| ...|.     ...           |..  |  . .   ..| .... .|               |. .|... . ..  .|  | . .|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LDW-------------------TNDDFRNIYQ--TLEMNEIA-----YYMYKVLQALDFAHSRG-IMHRDIKPQNIMIDHSTK--KVSLIDWGLADFY--
..                     || |.|..|   .. ....     .|.. .||.|.. |. . | ||||||.||..| . |  .. .||.|.. .|  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

-------------VPGTAYQVRVA-TRNYK----APELLFGYTQYTPT---VDIWGLGCTFAAMLTKKSPLFRGRDNSE--------------LILRIAD
             ..    .  .. | ||.    |||.| |  .....   .|||.||. . .||. . . | ...  .              ..|.   
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQLYQNI

FIGSEEIENYLQKYKITISSHDITSRISGHKRRAHEFLKKDDTKNFITPEAEDLLM----KMLTVDHQERISAKDAMMHPFF
. .  .. .. ..                                 . |||.|..     ||| ..  .||...... ||.|
KQKNIQFPKFPWQQ----------------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81840.m00170.AA CDK5 36-246 33 5.8e-34 104.35 In-house 1-218 (287) Show / Hide 
Range on Protein: 36-246
Range on HMM: 1-218/287
Sequence Identity: 33% (74 aa)

YELCYRIGRGKYSTVFSGLTNTGQQCVLKVLKPVRASKI--------NREIRILEKLKESPNICNLLDVVKDQESQMVTLVLDWTNDD----FRNIYQTL
||   .|| | | ||. ..  . .  |   || ||             ||| .|  ||  .||  | ||.     .  |||  .  .|    . ..   .
YEKMEKIGEGTYGTVYKARNKETHEIV--ALKRVRLDSEDEGVPSTAIREICLLKELKH-KNIVRLHDVIHSE--KKLTLVFEFCDQDLKKYMDSCNGEM

EMNEIAYYMYKVLQALDFAHSRGIMHRDIKPQNIMIDHSTKKVSLIDWGLA-DFYVPGTAYQVRVATRNYKAPELLFGYTQYTPTVDIWGLGCTFAAMLT
.|. | ..||  |. | | |.. ..||| |||| .|     .  | | |||  | .|   |   | |  | .|  |.|  .|.  .|.|  || || |  
DMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNG-ELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMAN

KKSPLFRGRDNSELILRIADFIGS
   ||| | | ..   || . .|.
AGRPLFPGNDVEDQLKRIFKIMGT
Kinase 81840.m00170.AA MAPK 187-246 43 7.2e-19 61.7 In-house 192-253 (328) Show / Hide 
Range on Protein: 187-246
Range on HMM: 192-253/328
Sequence Identity: 43% (27 aa)

VATRNYKAPELLFG--YTQYTPTVDIWGLGCTFAAMLTKKSPLFRGRDNSELILRIADFIGS
|||| | |||....  .. || .||.| .|| || |||   |||.|.|  . . .| ...|.
VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGT
Kinase 81840.m00170.AA CDC2 280-320 51 4.3e-13 36.05 In-house 262-301 (301) Show / Hide 
Range on Protein: 280-320
Range on HMM: 262-301/301
Sequence Identity: 51% (21 aa)

LKKDDTKNFITPEAEDLLMKMLTVDHQERISAKDAMMHPFF
.|| .   ...||. ||||.||  | | |||||.|. ||.|
QKKKNQ-SCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase 81840.m00170.AA CDK5 295-320 57 7.8e-11 29.97 In-house 262-287 (287) Show / Hide 
Range on Protein: 295-320
Range on HMM: 262-287/287
Sequence Identity: 57% (15 aa)

DLLMKMLTVDHQERISAKDAMMHPFF
||| ||| .. ..|||||.|..||.|
DLLQKMLQCNPNQRISAKAALHHPYF
Kinase 81840.m00170.AA MAPK 36-160 27 3.1e-10 31.35 In-house 1-151 (328) Show / Hide 
Range on Protein: 36-160
Range on HMM: 1-151/328
Sequence Identity: 27% (41 aa)

YELCYRIGRGKYSTVFS---GL----TNTGQQCVLKVLK-----PVRASKINREIRILEKLKESPNICNLLDVVKD-----QES----QMVTLVLDWTND
|..  .|| | | .|.|    .    |..|.. ..| .      |. .  . |||..|  ... .|| .|||. .      |.|    . . .| .    
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DFRNIYQ---TLEMNEIAYYMYKVLQA--LDFAHSRGIMHRDIKPQNIMID
| ..| .   .|.   | | || .| .  | . || .. |||.|| || ..
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN
Kinase 81840.m00170.AA MAPK 290-320 48 4.9e-10 30.68 In-house 298-328 (328) Show / Hide 
Range on Protein: 290-320
Range on HMM: 298-328/328
Sequence Identity: 48% (15 aa)

TPEAEDLLMKMLTVDHQERISAKDAMMHPFF
.|.| ||| |||. | ..||....|. ||.|
NPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 81840.m00170.AA TyrKc 36-320 17 2.2e-08 -87.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 36-320
Range on HMM: 1-280/280
Sequence Identity: 17% (57 aa)

YELCYRIGRGKYSTVFSGLTNTGQQCVLKVLKPVRASKINREIRILEKL-KESPNICNLLDVVKD--------QESQMVTLVLDWTN-DDFRNIYQT-LE
 .|   .|.| . .|. |  .  .|.  |.||.     . ||.||. || .. ||| .|. |. .        .   .|.   .. . .|.   ..  | 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

MNEIAYYMYKVLQALDFAHSRGIMHRDIKPQNIMIDHST-KKVSLIDWGLADFYVPG------TAYQVR----VAT--RNYK--APELLFGYTQYTPTVD
| .  .... . .  .. ||... |||.   |.....    |.|  | ||. .   .      . | .      .     ..  ||| .  |  .|.  |
MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKIS--DFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

IWGLGCTFAAMLTKKSPLFRG-----RDNSELILRIADFIGSEEIENYLQKYKITISSHDITSRISGHKRRAHEFLKKDDTKNF--ITPEAEDLLMKMLT
.|  | .   ..|   .   |      .|.|.| .. .    .  .|..      .|                          |   ..|  ..  .   
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MS--------------------------FVCCPDEMYQIMKQCWH

VDHQERISAKDAMMHPFF
 |  .| . ..   | .|
EDPEDRPTFSEI--HECF