CG10673

Species: Fruit Fly
Alias: CG10673, SFO177
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 64C9,

Classification

Group: Other
Family: Bud32

Sequence

Name Sequence Type Origin Length Description Download
CG10673.AA Protein Various 224 None Fasta, JSON
CG10673.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 222 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of CG10673.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG10673.AA Bud32 1-222 44 1.5e-160 517.65 In-house 1-269 (269) Show / Hide
Range on Protein: 1-222
Range on HMM: 1-269/269
Sequence Identity: 44% (121 aa)

MSLEILK--------QGAEGRLYL--------------GDFKGE------ACLIKERFVKKYRHPELNTQITRQRMKAEAKASGRCLAAGILAPKILHSD
||||..|        ||||.|...              ..|.|.      .|.|||||.|.||||.|..|.|..|.|.|..|..||..|||..|.....|
MSLELYKDVDIAPISQGAEARVFYTCYLTVSKQKVYTTCNFQGRAKDSHQQCIIKERFPKAYRHPQLDQQLTKHRTKQEVRAMNRCRKAGICVPYVYFCD

LNTHKLYMEYFDAA------KTAKQFIQETVSTQTEDEAKKCLLEFCTRIGEIIGKMHSNHIIHGDLTTSNILINPKGGDY-----DVILIDFGLSHYNQ
...|..||||....      .|.|..|.....||.||....||.|||...|..|||||.||||||||||||........|.     ...|||||||....
NYNHCIYMEYIEESPGGHGFYTVKNYIWQHQETQKEDQHDQCLREFCKKVGRQIGKMHWNHIIHGDLTTSNMMLRHPYADWTKLYGQMHLIDFGLSYISN

AT-EDKGVDLYVLERALLSTHSEQPY-----IFEHVLAAYR---TACGKDEQAVLTKFEEVRARGRKRTM
.. |||||||||||||.||||.....     ||||....||   |.| |...|||.||.|||.|||||||
SVPEDKGVDLYVLERAFLSTHPKCEQKYNAWIFEHFMENYRKQDTKC-KKFKAVLKKFNEVRLRGRKRTM

Kinase CG10673.AA Ciliate-C3 77-154 32 2.9e-09 29.56 In-house 62-140 (140) Show / Hide
Range on Protein: 77-154
Range on HMM: 62-140/140
Sequence Identity: 32% (27 aa)

KLYMEYFDAAKTAKQFIQETV-STQTEDEAKK----CLLEFCTRIGEIIGKMHSNHIIHGDLTTSNILINPKGGDYDVILIDF
....|||.  .| ..||.|   . . .|  .|      |.    |   |  .|   |.|||.  |||||| |.   .. .|||
QIFLEYFE-GQTLEKFINEIYDNKKYQDQNHKDLKLQKLQISKQILQAIDYLHEHNIVHGDIKFSNILINSKD---EIKIIDF

Kinase CG10673.AA Ciliate-E2 123-157 41 3.2e-09 27.8 In-house 176-203 (365) Show / Hide
Range on Protein: 123-157
Range on HMM: 176-203/365
Sequence Identity: 41% (15 aa)

MHSNH-IIHGDLTTSNILINPKGGDYDVILIDFGLS
.||.. ||| |.  .|||.        . .||||||
LHSKNNIIHRDIKPENILF--------IKIIDFGLS

Kinase CG10673.AA Ciliate-E2-Unclassified 120-161 37 1.8e-08 25.48 In-house 156-198 (352) Show / Hide
Range on Protein: 120-161
Range on HMM: 156-198/352
Sequence Identity: 37% (16 aa)

IGKMHSNH-IIHGDLTTSNILINPKGGDYDVILIDFGLSHYNQ
. ..|... ||| |.. .|||.. .|. | . .||||.| ..|
LEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

Kinase CG10673.AA Ciliate-B3 109-155 37 2e-08 26.93 In-house 2-49 (69) Show / Hide
Range on Protein: 109-155
Range on HMM: 2-49/69
Sequence Identity: 37% (18 aa)

LLEFCTRIGEIIGKMHSNHIIHGDLTTSNILINPKGG-DYDVILIDFG
 |.. ... | | ..|.  | | |.   |||.| ..  .| ||.||||
ALKHFHQVVEKIKILHEKNICHCDIKVDNILVNQQDKENYKVIIIDFG

Kinase CG10673.AA VRK 123-158 37 5.6e-08 22.11 In-house 146-181 (284) Show / Hide
Range on Protein: 123-158
Range on HMM: 146-181/284
Sequence Identity: 37% (14 aa)

MHSNHIIHGDLTTSNILINPKGGDYD-VILIDFGLSH
.|.|   |||.. .||| ..  ...| | |.|.||..
LHENEYVHGDIKAANILLGFE-KNPDQVYLVDYGLAY

Kinase CG10673.AA CMGC 123-157 29 6.4e-08 21.14 In-house 198-251 (513) Show / Hide
Range on Protein: 123-157
Range on HMM: 198-251/513
Sequence Identity: 29% (16 aa)

MHSNH--IIHGDLTTSNILINPKG-----------------GDYDVILIDFGLS
.||.   ||| ||  .|||||...                  .. . ..||||.
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA

Kinase CG10673.AA CAMK 123-159 27 8.2e-08 20.49 In-house 195-245 (425) Show / Hide
Range on Protein: 123-159
Range on HMM: 195-245/425
Sequence Identity: 27% (14 aa)

MHSNHIIHGDLTTSNILINPKGGD--------------YDVILIDFGLSHY
.||..|.| ||   |||.. ...|              ... .||||.. .
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANK

Kinase CG10673.AA STE 124-157 44 2.2e-07 22.29 In-house 169-194 (359) Show / Hide
Range on Protein: 124-157
Range on HMM: 169-194/359
Sequence Identity: 44% (15 aa)

HSNHIIHGDLTTSNILINPKGGDYDVILIDFGLS
||.|||| |.  .|||.        | |.|||..
HSHHIIHRDIKPANILL--------VKLCDFGVC

Kinase CG10673.AA TKL 123-166 25 3.4e-07 21.95 In-house 148-210 (364) Show / Hide
Range on Protein: 123-166
Range on HMM: 148-210/364
Sequence Identity: 25% (16 aa)

MHSNH--------IIHGDLTTSNILINPKG-----------GDYDVILIDFGLSHYNQATEDK
.||..        ||| ||...|||.. ..            |... . |||||  .. ....
LHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNM

Kinase CG10673.AA S_TKc 3-223 14 3.2e-05 -100.35 SMART 4-231 (231) Show / Hide
Range on Protein: 3-223
Range on HMM: 4-231/231
Sequence Identity: 14% (38 aa)

LEILKQGAEGRLYLGDFKG--EACLIKERFVKKYRHPELNTQITRQRMKAEAKASGRCLAAGILAPKILHSDLNTHKLYMEYFDA-AKTAKQFIQETVS-
|... .|| |. |..  |.  . . ||.                 .... | .   .     |   .    | .   . ||| |  . . ...|..  . 
LRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

----TQTEDEAKKCLLEFCTRIGEIIGKMHSNHIIHGDLTTSNILINPKGGDYDVILIDFGLSHYNQATE--------------DK-GVDLY--------
      .| .|.. . .    | . .  .||..||| ||  .|||..       . ..||||.     |               .|  .| .        
GLRFPFPE-HARFYMYQ----ICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYE

-VLERALLSTHSEQPYIFEHVLAAYRTACGKDEQAVLTKFEEVRAR------GRK-------RTMI
 .  . . .   ..  .|....        ..    . |  ..  .        .          .
MLCGYPPFP---QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF