Gene 5990 (Tetrahymena)
5990
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 5990.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 5990.AA | Ciliate-E4 | 155-191 | 35 | 3.3e-09 | 27.31 | In-house | 115-150 (150) | Show / Hide |
Range on Protein: 155-191 Range on HMM: 115-150/150 Sequence Identity: 35% (13 aa) QLIEALSLLHERGLYHGGVKASNIFVDENSNQIRIID ..| |.. | ...|| .|.||||.|.. . |.| CCINAMYYLQQVNITHGDLKPSNIFFDQYF-MVKIAD |
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| Kinase | 5990.AA | Ciliate-E2-Unclassified | 149-194 | 27 | 8.3e-08 | 23.19 | In-house | 140-193 (352) | Show / Hide |
Range on Protein: 149-194 Range on HMM: 140-193/352 Sequence Identity: 27% (15 aa) IQ-----KWIDQLIEALSLLHERG-LYHGGVKASNIFVDENSN--QIRIIDYGF .. ... |....|. ||. . | | .||..|.| . .|.|||.|. AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI |
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| Kinase | 5990.AA | VRK | 155-194 | 35 | 3.3e-07 | 19.6 | In-house | 138-179 (284) | Show / Hide |
Range on Protein: 155-194 Range on HMM: 138-179/284 Sequence Identity: 35% (15 aa) QLIEALSLLHERGLYHGGVKASNIFVDE--NSNQIRIIDYGF ... .| ||| . || .||.||.... | .| .|||. RMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGL |
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| Kinase | 5990.AA | CK2 | 149-193 | 35 | 4.1e-07 | 16.47 | In-house | 97-141 (288) | Show / Hide |
Range on Protein: 149-193 Range on HMM: 97-141/288 Sequence Identity: 35% (16 aa) IQKWIDQLIEALSLLHERGLYHGGVKASNIFVDENSNQIRIIDYG |. .. .| || | | | || .|| .| . . |.|| | IRYYMFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWG |
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| Kinase | 5990.AA | Ciliate-C4 | 148-193 | 29 | 4.4e-07 | 18.37 | In-house | 141-194 (361) | Show / Hide |
Range on Protein: 148-193 Range on HMM: 141-194/361 Sequence Identity: 29% (16 aa) LIQKWIDQLIEALSLLHERGLYHGGVKASNIFVDEN--------SNQIRIIDYG | | | .. .||..||. . |. .| .|| |. .|. .||.| LCKKFIQHICHALWHLHQNKWVHCDIKPENILVKYKSDFGGSNNIQQVKLIDFG |
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| Kinase | 5990.AA | Ciliate-E2 | 152-194 | 34 | 6.5e-07 | 19.75 | In-house | 165-202 (365) | Show / Hide |
Range on Protein: 152-194 Range on HMM: 165-202/365 Sequence Identity: 34% (15 aa) WIDQLIEALSLLHERG-LYHGGVKASNIFVDENSNQIRIIDYGF .| ..|.|| ||... | | .||.. | ||| |. YIACIILALEYLHSKNNIIHRDIKPENILF------IKIIDFGL |
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| Kinase | 5990.AA | Ciliate-C3 | 155-192 | 39 | 9.4e-07 | 20.58 | In-house | 104-140 (140) | Show / Hide |
Range on Protein: 155-192 Range on HMM: 104-140/140 Sequence Identity: 39% (15 aa) QLIEALSLLHERGLYHGGVKASNIFVDENSNQIRIIDY |.. |. ||| . || .| ||| . . ..|.|||. QILQAIDYLHEHNIVHGDIKFSNILINSK-DEIKIIDF |
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| Kinase | 5990.AA | PEK | 144-193 | 31 | 9.9e-07 | 18.65 | In-house | 424-477 (655) | Show / Hide |
Range on Protein: 144-193 Range on HMM: 424-477/655 Sequence Identity: 31% (17 aa) NRFDLIQKWIDQLIEALSLLHERGLYHGGVKASNIFVDENSN----QIRIIDYG . |...... |..|.| .|..|. | |.||||.| ... |..| |.| WDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFLDCDGQHHQMQVKIGDFG |
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| Kinase | 5990.AA | Ciliate-E6 | 155-197 | 37 | 1e-06 | 17.32 | In-house | 61-102 (154) | Show / Hide |
Range on Protein: 155-197 Range on HMM: 61-102/154 Sequence Identity: 37% (16 aa) QLIEALSLLHERGLYHGGVKASNIFVDENSNQIRIIDYGFYSS || .|.. || ..... . |||.|.| | | | | || .. QLFHAVEYLHSKNYVLQNITLKNIFLDKNMN-IKICDFGFQQC |
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| Kinase | 5990.AA | CAMKL | 155-194 | 43 | 2e-06 | 16.13 | In-house | 135-175 (297) | Show / Hide |
Range on Protein: 155-194 Range on HMM: 135-175/297 Sequence Identity: 43% (18 aa) QLIEALSLLHERGLYHGGVKASNIFVDENSN-QIRIIDYGF |...|.. .|..| | |. || .||| | .| ||| || QIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGF |
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| S_TKc | 5990.AA | S_TKc | 39-307 | 16 | 2.5e-05 | -98.65 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 39-307
Range on HMM: 1-231/231
Sequence Identity: 16% (46 aa)
IVTNQIIGSSGNSFMLKCNQKTPNGIIIL-TVRAIMVNSYSTLSNAVELYENQVDIKYVSEYIQVYDSFCYNKNDEVMNYVRR--GFYRYTIDEMYKLNS
..||. . . || | . | . .. .. . ... .. . ... .. |... .. || |. | .....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLG-------DLFDYIK
SFKGQGV---LNRFDLIQKWIDQLIEALSLLHERGLYHGGVKASNIFVDENSNQIRIIDYGFYSSHVNLMNQNYSKDVYTPL-----VFNELANSFDQ-K
. ...| .. ..... |...|| .|..| | .| .||..|| .| |.| |. . . || |. ... |
KRGRHGLRFPFPE--HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--------TTFCGTPWYMAPEVL-----GYGKCK
RFNDIYALIILIYQMAFG---FDNSHYQIKQLQKGITFNDEDDGRDHESDDTYEFKLRIIKLVNK--IVCKAALGTEEQRKKITLF
|.... ...| |. | |. |.... | | |.. .| .. . . . . || |. |. |
--CDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 5990.AA | Pkinase | 147-194 | 26 | 0.000378 | 15.75 | Pfam | 108-158 (293) | Show / Hide |
Range on Protein: 147-194 Range on HMM: 108-158/293 Sequence Identity: 26% (14 aa) DLIQKWIDQLIEALSLLHERGLYHGGVKASNIFVDENSNQI----RIIDYGF . ..... |....| .|..| | .| .||..| | ..| .|.| |. WECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGL |
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| MORN | 5990.AA | MORN | 757-779 | 34 | 6.1e-05 | 22.69 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 757-779 Range on HMM: 1-23/23 Sequence Identity: 34% (8 aa) YEGSFKDDFYHGFGMEYYENGQI |||..|... ||.| .. .| YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 5990.AA | MORN | 733-755 | 34 | 8.2e-05 | 22.23 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 733-755 Range on HMM: 1-23/23 Sequence Identity: 34% (8 aa) YEGQIQSGQKNGYGVLYNCNGTK |||. . |...|.||.. .|.. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN_2 | 5990.AA | MORN_2 | 790-811 | 45 | 0.001468 | 16.96 | Pfam | 1-22 (22) | Show / Hide |
Range on Protein: 790-811 Range on HMM: 1-22/22 Sequence Identity: 45% (10 aa) LNGFAKTFYKNGSLCYEGDYVE |.| .|..|.|| | ||. |. LHGEWKWYYENGKLKYEINYKN |
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| MORN | 5990.AA | MORN | 803-824 | 31 | 0.001835 | 14.85 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 803-824 Range on HMM: 1-22/22 Sequence Identity: 31% (7 aa) LCYEGDYVEGICHGNGTKYDES .|||....| .||.|. . . DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 5990.AA | MORN | 731-752 | 36 | 0.002488 | 13.86 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 731-752 Range on HMM: 1-22/22 Sequence Identity: 36% (8 aa) IQYEGQIQSGQKNGYGVLYNCN |||. . |.. |.||.. | DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 5990.AA | MORN | 755-776 | 31 | 0.002858 | 13.41 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 755-776 Range on HMM: 1-22/22 Sequence Identity: 31% (7 aa) KMYEGSFKDDFYHGFGMEYYEN .|||..... ||.| .. | DRYEGEWHNGKRHGHGVYWWAN |
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| MORN_2 | 5990.AA | MORN_2 | 766-787 | 36 | 0.003538 | 15.62 | Pfam | 1-22 (22) | Show / Hide |
Range on Protein: 766-787 Range on HMM: 1-22/22 Sequence Identity: 36% (8 aa) YHGFGMEYYENGQILHQGNFEK || .|||||... ..|... LHGEWKWYYENGKLKYEINYKN |
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| MORN | 5990.AA | MORN | 805-827 | 30 | 0.004243 | 16.01 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 805-827 Range on HMM: 1-23/23 Sequence Identity: 30% (7 aa) YEGDYVEGICHGNGTKYDESSSN |||....| .||.|. . . . YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 5990.AA | MORN | 781-803 | 17 | 0.199425 | 9.94 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 781-803 Range on HMM: 1-23/23 Sequence Identity: 17% (4 aa) HQGNFEKGLLNGFAKTFYKNGSL .|.. .|. .|. . ...|. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN_2 | 5990.AA | MORN_2 | 742-763 | 31 | 1.483707 | 6.42 | Pfam | 1-22 (22) | Show / Hide |
Range on Protein: 742-763 Range on HMM: 1-22/22 Sequence Identity: 31% (7 aa) KNGYGVLYNCNGTKMYEGSFKD ..| |. || .||...|. LHGEWKWYYENGKLKYEINYKN |
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| MORN_2 | 5990.AA | MORN_2 | 815-835 | 28 | 96.715615 | 0.05 | Pfam | 2-22 (22) | Show / Hide |
Range on Protein: 815-835 Range on HMM: 2-22/22 Sequence Identity: 28% (6 aa) HGNGTKYDESSSNFQQGQYQN || ..|.|. ....|.| HGEWKWYYENGKLKYEINYKN |
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| MORN_2 | 5990.AA | MORN_2 | 838-859 | 40 | 0.000835 | 17.82 | Pfam | 1-22 (22) | Show / Hide |
Range on Protein: 838-859 Range on HMM: 1-22/22 Sequence Identity: 40% (9 aa) MIGVHKKYQQNGQIIFETNFKN . |. |.| ||... |.|.|| LHGEWKWYYENGKLKYEINYKN |
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| MORN_2 | 5990.AA | MORN_2 | 862-883 | 31 | 0.001222 | 17.24 | Pfam | 1-22 (22) | Show / Hide |
Range on Protein: 862-883 Range on HMM: 1-22/22 Sequence Identity: 31% (7 aa) RDGKSIEYHQQGGISFEGTYKN ..|....|. | . |..||| LHGEWKWYYENGKLKYEINYKN |
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| MORN | 5990.AA | MORN | 877-898 | 39 | 0.033979 | 12.73 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 877-898 Range on HMM: 1-23/23 Sequence Identity: 39% (9 aa) FEGTYKNGKKM-NGIEYDHDGNK .||..||||. .|. . ||.. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 5990.AA | MORN | 853-875 | 26 | 42.880535 | 1.47 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 853-875 Range on HMM: 1-23/23 Sequence Identity: 26% (6 aa) FETNFKNNKRDGKSIEYHQQGGI .| ..||.|..|. . . |. YEGEWKNGKMHGHGVYTWPDGDR |
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